CA3176556A1 - Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules - Google Patents
Anti-betacellulin antibodies, fragments thereof, and multi-specific binding moleculesInfo
- Publication number
- CA3176556A1 CA3176556A1 CA3176556A CA3176556A CA3176556A1 CA 3176556 A1 CA3176556 A1 CA 3176556A1 CA 3176556 A CA3176556 A CA 3176556A CA 3176556 A CA3176556 A CA 3176556A CA 3176556 A1 CA3176556 A1 CA 3176556A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063052789P | 2020-07-16 | 2020-07-16 | |
| US63/052,789 | 2020-07-16 | ||
| US202163156709P | 2021-03-04 | 2021-03-04 | |
| US63/156,709 | 2021-03-04 | ||
| PCT/IB2021/056363 WO2022013787A1 (en) | 2020-07-16 | 2021-07-14 | Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3176556A1 true CA3176556A1 (en) | 2022-01-20 |
Family
ID=76971949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3176556A Pending CA3176556A1 (en) | 2020-07-16 | 2021-07-14 | Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US11524998B2 (enExample) |
| EP (1) | EP4182025A1 (enExample) |
| JP (1) | JP2023534214A (enExample) |
| CN (1) | CN116323664A (enExample) |
| AU (1) | AU2021308712B2 (enExample) |
| BR (1) | BR112023000482A2 (enExample) |
| CA (1) | CA3176556A1 (enExample) |
| CL (2) | CL2023000084A1 (enExample) |
| CO (1) | CO2023000112A2 (enExample) |
| CR (1) | CR20230009A (enExample) |
| DO (1) | DOP2023000005A (enExample) |
| EC (1) | ECSP23001118A (enExample) |
| IL (1) | IL299586A (enExample) |
| MX (1) | MX2023000547A (enExample) |
| PE (1) | PE20231093A1 (enExample) |
| PH (1) | PH12023550015A1 (enExample) |
| TW (1) | TW202216761A (enExample) |
| UY (1) | UY39324A (enExample) |
| WO (1) | WO2022013787A1 (enExample) |
| ZA (1) | ZA202304787B (enExample) |
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| NZ770284A (en) | 2018-05-10 | 2025-11-28 | Regeneron Pharma | High concentration vegf receptor fusion protein containing formulations |
| PH12023550015A1 (en) * | 2020-07-16 | 2024-03-11 | Novartis Ag | Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules |
| WO2025119329A1 (zh) * | 2023-12-07 | 2025-06-12 | 信达生物制药(苏州)有限公司 | 抗c5和htra1双特异性抗体及其用途 |
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| US20220356236A1 (en) | 2022-11-10 |
| CL2024003614A1 (es) | 2025-04-21 |
| AU2021308712A1 (en) | 2023-02-02 |
| ECSP23001118A (es) | 2023-03-31 |
| US11524998B2 (en) | 2022-12-13 |
| BR112023000482A2 (pt) | 2023-01-31 |
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| US20220025032A1 (en) | 2022-01-27 |
| ZA202304787B (en) | 2025-10-29 |
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