CA3022830A1 - Bioresorbable ocular drug delivery device - Google Patents
Bioresorbable ocular drug delivery device Download PDFInfo
- Publication number
- CA3022830A1 CA3022830A1 CA3022830A CA3022830A CA3022830A1 CA 3022830 A1 CA3022830 A1 CA 3022830A1 CA 3022830 A CA3022830 A CA 3022830A CA 3022830 A CA3022830 A CA 3022830A CA 3022830 A1 CA3022830 A1 CA 3022830A1
- Authority
- CA
- Canada
- Prior art keywords
- implant
- drug
- outer shell
- eye
- ocular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts or implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
- A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Prostheses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662325378P | 2016-04-20 | 2016-04-20 | |
| US62/325,378 | 2016-04-20 | ||
| PCT/US2017/028665 WO2017184881A1 (en) | 2016-04-20 | 2017-04-20 | Bioresorbable ocular drug delivery device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3022830A1 true CA3022830A1 (en) | 2017-10-26 |
Family
ID=58672714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3022830A Pending CA3022830A1 (en) | 2016-04-20 | 2017-04-20 | Bioresorbable ocular drug delivery device |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US11318043B2 (enExample) |
| EP (1) | EP3442479B1 (enExample) |
| JP (3) | JP7003110B2 (enExample) |
| CN (2) | CN109937025B (enExample) |
| AU (2) | AU2017252294B2 (enExample) |
| CA (1) | CA3022830A1 (enExample) |
| WO (1) | WO2017184881A1 (enExample) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8663303B2 (en) | 2010-11-15 | 2014-03-04 | Aquesys, Inc. | Methods for deploying an intraocular shunt from a deployment device and into an eye |
| AU2007319383A1 (en) | 2006-11-10 | 2008-05-22 | Glaukos Corporation | Uveoscleral shunt and methods for implanting same |
| US9011361B2 (en) * | 2007-09-07 | 2015-04-21 | Mati Therapeutics Inc. | Lacrimal implant detection |
| JP5937004B2 (ja) | 2009-05-18 | 2016-06-22 | ドーズ メディカル コーポレーションDose Medical Corporation | 薬剤溶出眼内インプラント |
| US12478503B2 (en) | 2009-05-18 | 2025-11-25 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| US9668915B2 (en) | 2010-11-24 | 2017-06-06 | Dose Medical Corporation | Drug eluting ocular implant |
| US9808373B2 (en) | 2013-06-28 | 2017-11-07 | Aquesys, Inc. | Intraocular shunt implantation |
| US9554940B2 (en) | 2012-03-26 | 2017-01-31 | Glaukos Corporation | System and method for delivering multiple ocular implants |
| US10517759B2 (en) | 2013-03-15 | 2019-12-31 | Glaukos Corporation | Glaucoma stent and methods thereof for glaucoma treatment |
| US9592151B2 (en) | 2013-03-15 | 2017-03-14 | Glaukos Corporation | Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye |
| MX2016006297A (es) | 2013-11-14 | 2016-07-26 | Aquesys Inc | Insertador de derivacion intraocular. |
| AU2015266850B2 (en) | 2014-05-29 | 2019-12-05 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| CA2980289C (en) | 2015-03-20 | 2024-05-14 | Glaukos Corporation | Gonioscopic devices |
| WO2017040853A1 (en) | 2015-09-02 | 2017-03-09 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
| US11564833B2 (en) | 2015-09-25 | 2023-01-31 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
| CA3022830A1 (en) | 2016-04-20 | 2017-10-26 | Harold Alexander Heitzmann | Bioresorbable ocular drug delivery device |
| WO2017201255A1 (en) * | 2016-05-20 | 2017-11-23 | The Regents Of The University Of Colorado, A Body Corporate | Lacrimal drug delivery device |
| WO2018067882A1 (en) * | 2016-10-05 | 2018-04-12 | Titan Pharmaceuticals, Inc. | Implantable devices for drug delivery with reduced burst release |
| US10674906B2 (en) | 2017-02-24 | 2020-06-09 | Glaukos Corporation | Gonioscopes |
| US11116625B2 (en) | 2017-09-28 | 2021-09-14 | Glaukos Corporation | Apparatus and method for controlling placement of intraocular implants |
| CN113893085B (zh) | 2017-10-06 | 2024-05-24 | 格劳科斯公司 | 用于递送多个眼部植入物的系统和方法 |
| USD846738S1 (en) | 2017-10-27 | 2019-04-23 | Glaukos Corporation | Implant delivery apparatus |
| AU2017439185B2 (en) * | 2017-11-08 | 2021-05-13 | Aquesys, Inc. | Manually adjustable intraocular flow regulation |
| US11246753B2 (en) | 2017-11-08 | 2022-02-15 | Aquesys, Inc. | Manually adjustable intraocular flow regulation |
| US10952898B2 (en) | 2018-03-09 | 2021-03-23 | Aquesys, Inc. | Intraocular shunt inserter |
| US11135089B2 (en) | 2018-03-09 | 2021-10-05 | Aquesys, Inc. | Intraocular shunt inserter |
| CA3095730A1 (en) * | 2018-03-30 | 2019-10-03 | Aerie Pharmaceuticals, Inc. | Mono-(acid) salts of 6-aminoisoquinolines and uses thereof |
| US20200375891A1 (en) * | 2019-05-31 | 2020-12-03 | Dose Medical Corporation | Bioerodible cross-linked hydrogel implants and related methods of use |
| CA3144406A1 (en) | 2019-06-27 | 2020-12-30 | Layerbio, Inc. | Ocular device delivery methods and systems |
| CN111150545A (zh) * | 2020-01-02 | 2020-05-15 | 首都医科大学附属北京同仁医院 | 一种相变降温支架及其制备方法和相变降温组合支架 |
| KR102154490B1 (ko) * | 2020-01-03 | 2020-09-10 | 최만규 | 모델 하우스의 전시용 실내벽체 및 그 설치방법 |
| CN111228034A (zh) * | 2020-01-16 | 2020-06-05 | 贵州省人民医院 | 一种载药控释型泪道栓子及其制备方法 |
| WO2021158013A1 (en) * | 2020-02-04 | 2021-08-12 | Korea Atomic Energy Research Institute | Hydrogel and method for preparing the same |
| EP4161410A4 (en) * | 2020-06-03 | 2024-07-17 | Northeastern University | Biodegradable implant for sustained trans-nasal delivery of therapeutic agents to the brain |
| WO2021247690A1 (en) * | 2020-06-03 | 2021-12-09 | Glaukos Corporation | Rho kinase inhibitor releasing implants and related methods of use |
| CN111772920B (zh) * | 2020-07-22 | 2025-01-07 | 苏州朗目医疗科技有限公司 | 青光眼引流装置及其引流植入物 |
| US12268633B2 (en) * | 2020-11-04 | 2025-04-08 | Alcon Inc. | Medical implant |
| JP2024522285A (ja) * | 2021-05-27 | 2024-06-13 | ダブリュ.エル.ゴア アンド アソシエイツ,インコーポレイティド | 薬物療法送達システム及び方法 |
| WO2022251710A2 (en) * | 2021-05-28 | 2022-12-01 | Sight Sciences, Inc. | Intraocular devices, systems, and methods |
| WO2023059933A1 (en) * | 2021-10-08 | 2023-04-13 | Purdue Research Foundation | Ocular drug delivery device and related methods |
| US20240024093A1 (en) | 2022-07-22 | 2024-01-25 | SpyGlass Pharma, Inc. | Intraocular drug delivery systems and methods of use |
| CN115969612A (zh) * | 2022-12-20 | 2023-04-18 | 重庆医科大学附属第三医院(捷尔医院) | 可生物降解的用于治疗青光眼的房水引流装置及其制备方法 |
| CN121263156A (zh) * | 2023-06-08 | 2026-01-02 | W.L.戈尔及同仁股份有限公司 | 脉络膜上可植入装置及用于治疗眼内高血压的方法 |
| USD1137672S1 (en) | 2024-08-27 | 2026-07-28 | Glaukos Corporation | Drug eluting ocular implant |
| KR20260119037A (ko) * | 2025-01-24 | 2026-07-31 | 주식회사 위더스비전 | 녹내장 치료를 위한 미세다공성 약물 전달 매트릭스 및 이의 제조방법 |
Family Cites Families (647)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US663670A (en) | 1900-07-30 | 1900-12-11 | Marion W Wiswall | Apparel dusting-cap. |
| US2031754A (en) | 1932-11-04 | 1936-02-25 | Ernest J Sweetland | Extensible coupling |
| US3416530A (en) | 1966-03-02 | 1968-12-17 | Richard A. Ness | Eyeball medication dispensing tablet |
| US3710795A (en) | 1970-09-29 | 1973-01-16 | Alza Corp | Drug-delivery device with stretched, rate-controlling membrane |
| US4034756A (en) | 1971-01-13 | 1977-07-12 | Alza Corporation | Osmotically driven fluid dispenser |
| US4450150A (en) | 1973-05-17 | 1984-05-22 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery depots, and method for preparing and using the same |
| JPS5323011B2 (enExample) | 1973-09-12 | 1978-07-12 | ||
| US3961628A (en) | 1974-04-10 | 1976-06-08 | Alza Corporation | Ocular drug dispensing system |
| US3949750A (en) | 1974-10-07 | 1976-04-13 | Freeman Jerre M | Punctum plug and method for treating keratoconjunctivitis sicca (dry eye) and other ophthalmic aliments using same |
| US4093708A (en) | 1974-12-23 | 1978-06-06 | Alza Corporation | Osmotic releasing device having a plurality of release rate patterns |
| GB1508631A (en) | 1975-01-20 | 1978-04-26 | In Da Te Ag | Re-usable containers |
| US4207890A (en) | 1977-01-04 | 1980-06-17 | Mcneilab, Inc. | Drug-dispensing device and method |
| US4113088A (en) | 1977-06-06 | 1978-09-12 | Binkhorst Richard D | Sterile package |
| US4328803B1 (en) | 1980-10-20 | 1994-01-11 | Opthalmic Systems, Inc. | Opthalmological procedures |
| DK90883A (da) | 1982-03-18 | 1983-09-19 | Merck & Co Inc | Beholder til osmotisk afgivelse af et stof eller en stofblanding |
| US4468216A (en) | 1982-05-20 | 1984-08-28 | Rudolph Muto | Irrigation suction catheter |
| US4521210A (en) | 1982-12-27 | 1985-06-04 | Wong Vernon G | Eye implant for relieving glaucoma, and device and method for use therewith |
| US4955881A (en) | 1985-08-16 | 1990-09-11 | Alza Corporation | Ruminant dispensing device |
| US4883864A (en) | 1985-09-06 | 1989-11-28 | Minnesota Mining And Manufacturing Company | Modified collagen compound and method of preparation |
| GB8603099D0 (en) | 1986-02-07 | 1986-03-12 | Blass K G | Gastrointestinal module |
| US4743248A (en) | 1986-08-11 | 1988-05-10 | Alza Corporation | Dosage form for delivering acid sensitive beneficial agent |
| US4863457A (en) | 1986-11-24 | 1989-09-05 | Lee David A | Drug delivery device |
| US4736836A (en) | 1987-02-02 | 1988-04-12 | Alongi Salvatore A | Intraocular lens package |
| US4846793A (en) | 1987-03-18 | 1989-07-11 | Endocon, Inc. | Injector for implanting multiple pellet medicaments |
| US4828439A (en) | 1987-05-15 | 1989-05-09 | Giannuzzi Louis | Screw anchor |
| US4997652A (en) | 1987-12-22 | 1991-03-05 | Visionex | Biodegradable ocular implants |
| US4853224A (en) | 1987-12-22 | 1989-08-01 | Visionex | Biodegradable ocular implants |
| CA1334168C (en) | 1988-04-26 | 1995-01-31 | Louis M. De Santis | Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers |
| US5202128A (en) | 1989-01-06 | 1993-04-13 | F. H. Faulding & Co. Limited | Sustained release pharmaceutical composition |
| FR2644058B1 (fr) | 1989-03-10 | 1994-06-03 | France Chirurgie Instr | Bouchon meatique pour pathologie lacrymale |
| US5098443A (en) | 1989-03-23 | 1992-03-24 | University Of Miami | Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents |
| US5164188A (en) | 1989-11-22 | 1992-11-17 | Visionex, Inc. | Biodegradable ocular implants |
| US5324280A (en) | 1990-04-02 | 1994-06-28 | Alza Corporation | Osmotic dosage system for delivering a formulation comprising liquid carrier and drug |
| US5017381A (en) | 1990-05-02 | 1991-05-21 | Alza Corporation | Multi-unit pulsatile delivery system |
| US5128145A (en) | 1990-06-13 | 1992-07-07 | Alza Corporation | Dosage form for Parkinson's disease, spasticity and muscle spasms |
| US5725529A (en) | 1990-09-25 | 1998-03-10 | Innovasive Devices, Inc. | Bone fastener |
| US5378475A (en) | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
| US6007511A (en) | 1991-05-08 | 1999-12-28 | Prywes; Arnold S. | Shunt valve and therapeutic delivery system for treatment of glaucoma and methods and apparatus for its installation |
| CA2071137A1 (en) | 1991-07-10 | 1993-01-11 | Clarence C. Lee | Composition and method for revitalizing scar tissue |
| DK0601055T3 (da) | 1991-08-16 | 2000-10-02 | Joseph C Salamone | Medikamentovertrukket brydende okulært forkammerimplantat |
| US5464450A (en) | 1991-10-04 | 1995-11-07 | Scimed Lifesystems Inc. | Biodegradable drug delivery vascular stent |
| GB2260585A (en) | 1991-10-09 | 1993-04-21 | Avdel Systems Ltd | Self-plugging blind rivet |
| US5318780A (en) | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
| IL100112A (en) | 1991-11-21 | 1996-01-31 | Yeda Res & Dev | Microdelivery device for enhanced drug administration to the eye |
| US5384333A (en) | 1992-03-17 | 1995-01-24 | University Of Miami | Biodegradable injectable drug delivery polymer |
| AU4282793A (en) | 1992-04-10 | 1993-11-18 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University | A microneedle for injection of ocular blood vessels |
| US5380290A (en) | 1992-04-16 | 1995-01-10 | Pfizer Hospital Products Group, Inc. | Body access device |
| BR9306399A (pt) | 1992-05-22 | 1998-09-15 | Senju Pharma Co | Composição farmacéutica para uso no tratamento de glaucoma |
| US5629008A (en) | 1992-06-02 | 1997-05-13 | C.R. Bard, Inc. | Method and device for long-term delivery of drugs |
| US5767079A (en) | 1992-07-08 | 1998-06-16 | Celtrix Pharmaceuticals, Inc. | Method of treating ophthalmic disorders using TGF -β |
| WO1994002081A1 (en) | 1992-07-16 | 1994-02-03 | Wong Vernon G | Eye implant suitable for relief of glaucoma |
| US5709854A (en) | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
| US20030203976A1 (en) | 1993-07-19 | 2003-10-30 | William L. Hunter | Anti-angiogenic compositions and methods of use |
| DE69403966T3 (de) | 1993-07-19 | 2008-04-17 | Angiotech Pharmaceuticals, Inc., Vancouver | Anti-angiogene mittel und verfahren zu deren verwendung |
| US5731294A (en) | 1993-07-27 | 1998-03-24 | Hybridon, Inc. | Inhibition of neovasularization using VEGF-specific oligonucleotides |
| US5443505A (en) | 1993-11-15 | 1995-08-22 | Oculex Pharmaceuticals, Inc. | Biocompatible ocular implants |
| US5500465A (en) | 1994-03-10 | 1996-03-19 | Board Of Trustees Operating Michigan State University | Biodegradable multi-component polymeric materials based on unmodified starch-like polysaccharides |
| US5516522A (en) | 1994-03-14 | 1996-05-14 | Board Of Supervisors Of Louisiana State University | Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same |
| US6551618B2 (en) | 1994-03-15 | 2003-04-22 | University Of Birmingham | Compositions and methods for delivery of agents for neuronal regeneration and survival |
| GB9405304D0 (en) | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
| EP0754046A1 (en) | 1994-04-04 | 1997-01-22 | FREEMAN, William R. | Use of phosphonylmethoxyalkyl nucleosides for the treatment of raised intraocular pressure |
| US5466233A (en) | 1994-04-25 | 1995-11-14 | Escalon Ophthalmics, Inc. | Tack for intraocular drug delivery and method for inserting and removing same |
| WO1995030429A1 (en) | 1994-05-04 | 1995-11-16 | Board Of Trustees Of The University Of Arkansas | Novel ophthalmologic uses of protein c |
| US5599534A (en) | 1994-08-09 | 1997-02-04 | University Of Nebraska | Reversible gel-forming composition for sustained delivery of bio-affecting substances, and method of use |
| US5665114A (en) | 1994-08-12 | 1997-09-09 | Meadox Medicals, Inc. | Tubular expanded polytetrafluoroethylene implantable prostheses |
| SE9402816D0 (sv) | 1994-08-24 | 1994-08-24 | Pharmacia Ab | Method and meams for drug administration |
| GB9417399D0 (en) | 1994-08-30 | 1994-10-19 | Scherer Corp R P | Ocular treatment device |
| AU699821B2 (en) | 1994-10-17 | 1998-12-17 | Kabushikikaisha Igaki Iryo Sekkei | Stent for liberating drug |
| US6063396A (en) | 1994-10-26 | 2000-05-16 | Houston Biotechnology Incorporated | Methods and compositions for the modulation of cell proliferation and wound healing |
| US6063116A (en) | 1994-10-26 | 2000-05-16 | Medarex, Inc. | Modulation of cell proliferation and wound healing |
| US5643321A (en) | 1994-11-10 | 1997-07-01 | Innovasive Devices | Suture anchor assembly and methods |
| US5602143A (en) | 1994-12-08 | 1997-02-11 | Allergan | Method for reducing intraocular pressure in the mammalian eye by administration of guanylate cyclase inhibitors |
| US6228873B1 (en) | 1994-12-09 | 2001-05-08 | The Regents Of The University Of California | Method for enhancing outflow of aqueous humor in treatment of glaucoma |
| US5725493A (en) | 1994-12-12 | 1998-03-10 | Avery; Robert Logan | Intravitreal medicine delivery |
| US5891084A (en) | 1994-12-27 | 1999-04-06 | Lee; Vincent W. | Multiple chamber catheter delivery system |
| WO1996020742A1 (en) | 1995-01-06 | 1996-07-11 | Wong Vernon G | Improve eye implant for relief of glaucoma |
| EP0808160A1 (en) | 1995-02-10 | 1997-11-26 | The University Of Toronto Innovations Foundation | Deprenyl compounds for treatment of glaucoma |
| US6231600B1 (en) | 1995-02-22 | 2001-05-15 | Scimed Life Systems, Inc. | Stents with hybrid coating for medical devices |
| US5869079A (en) | 1995-06-02 | 1999-02-09 | Oculex Pharmaceuticals, Inc. | Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents |
| US6369116B1 (en) | 1995-06-02 | 2002-04-09 | Oculex Pharmaceuticals, Inc. | Composition and method for treating glaucoma |
| US6129761A (en) | 1995-06-07 | 2000-10-10 | Reprogenesis, Inc. | Injectable hydrogel compositions |
| US5773019A (en) | 1995-09-27 | 1998-06-30 | The University Of Kentucky Research Foundation | Implantable controlled release device to deliver drugs directly to an internal portion of the body |
| US5547993A (en) | 1995-10-24 | 1996-08-20 | Mitsubishi Chemical Corporation | Therapeutic agent for glaucoma |
| AU1201297A (en) | 1995-12-21 | 1997-07-17 | Pharmacia & Upjohn Ab | Ophthalmic treatment |
| US5798380A (en) | 1996-02-21 | 1998-08-25 | Wisconsin Alumni Research Foundation | Cytoskeletal active agents for glaucoma therapy |
| US6299895B1 (en) | 1997-03-24 | 2001-10-09 | Neurotech S.A. | Device and method for treating ophthalmic diseases |
| CA2249228A1 (en) | 1996-03-26 | 1997-10-02 | Cyril Hadyn Saunders | Composite closure, method for assembling it and method for closing a container with it |
| US5670161A (en) | 1996-05-28 | 1997-09-23 | Healy; Kevin E. | Biodegradable stent |
| US6120460A (en) | 1996-09-04 | 2000-09-19 | Abreu; Marcio Marc | Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions |
| US6544193B2 (en) | 1996-09-04 | 2003-04-08 | Marcio Marc Abreu | Noninvasive measurement of chemical substances |
| US5925342A (en) | 1996-11-13 | 1999-07-20 | Allergan | Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers |
| US20020111603A1 (en) | 1996-12-02 | 2002-08-15 | Societe De Conseils De Recherches Et D'application | Device for local administration of solid or semi-solid formulations and delayed-release formulations for proposal parental administration and preparation process |
| GB9700390D0 (en) | 1997-01-10 | 1997-02-26 | Biocompatibles Ltd | Device for use in the eye |
| FR2759577B1 (fr) | 1997-02-17 | 1999-08-06 | Corneal Ind | Implant de sclerectomie profonde |
| US5893837A (en) | 1997-02-28 | 1999-04-13 | Staar Surgical Company, Inc. | Glaucoma drain implanting device and method |
| US6059812A (en) | 1997-03-21 | 2000-05-09 | Schneider (Usa) Inc. | Self-expanding medical device for centering radioactive treatment sources in body vessels |
| DE19728069C1 (de) | 1997-07-01 | 1999-02-11 | Acritec Gmbh | Vorrichtung zur Messung des Augeninnendrucks |
| US5980928A (en) | 1997-07-29 | 1999-11-09 | Terry; Paul B. | Implant for preventing conjunctivitis in cattle |
| US6306426B1 (en) | 1997-08-11 | 2001-10-23 | Allergan Sales, Inc. | Implant device with a retinoid for improved biocompatibility |
| US6004302A (en) | 1997-08-28 | 1999-12-21 | Brierley; Lawrence A. | Cannula |
| US5902598A (en) | 1997-08-28 | 1999-05-11 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
| US6274138B1 (en) | 1997-09-03 | 2001-08-14 | Incyte Genomics, Inc. | Human mitochondrial malate dehydrogenase |
| US7985415B2 (en) | 1997-09-10 | 2011-07-26 | Rutgers, The State University Of New Jersey | Medical devices employing novel polymers |
| US20020164374A1 (en) | 1997-10-29 | 2002-11-07 | John Jackson | Polymeric systems for drug delivery and uses thereof |
| US6159458A (en) | 1997-11-04 | 2000-12-12 | Insite Vision | Sustained release ophthalmic compositions containing water soluble medicaments |
| US8313454B2 (en) | 1997-11-20 | 2012-11-20 | Optonol Ltd. | Fluid drainage device, delivery device, and associated methods of use and manufacture |
| US6203513B1 (en) | 1997-11-20 | 2001-03-20 | Optonol Ltd. | Flow regulating implant, method of manufacture, and delivery device |
| US7780623B2 (en) | 1998-01-29 | 2010-08-24 | Soltanpour David P | Implantable pump apparatuses |
| US6682500B2 (en) | 1998-01-29 | 2004-01-27 | David Soltanpour | Synthetic muscle based diaphragm pump apparatuses |
| US6589198B1 (en) | 1998-01-29 | 2003-07-08 | David Soltanpour | Implantable micro-pump assembly |
| US6290684B1 (en) | 1998-03-02 | 2001-09-18 | Herrick Family Limited Partnership | Punctum plug having a collapsible expanded section and distal tip extending substantially perpendicular thereto and method of inserting same |
| US6196993B1 (en) | 1998-04-20 | 2001-03-06 | Eyelab Group, Llc | Ophthalmic insert and method for sustained release of medication to the eye |
| FR2777442B1 (fr) | 1998-04-21 | 2000-07-28 | Tornier Sa | Ancre de suture a expansion reversible |
| US6268398B1 (en) | 1998-04-24 | 2001-07-31 | Mitokor | Compounds and methods for treating mitochondria-associated diseases |
| US5997498A (en) | 1998-05-07 | 1999-12-07 | Johns Hopkins University | Inline air humidifier, a system for humidifying air and methods related thereto |
| TW586944B (en) | 1998-05-29 | 2004-05-11 | Sumitomo Pharma | Controlled release agent having a multi-layer structure |
| US6231853B1 (en) | 1998-06-01 | 2001-05-15 | Incyte Pharmaceuticals, Inc. | Human glutathione peroxidase-6 |
| US6503231B1 (en) | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
| US6378526B1 (en) | 1998-08-03 | 2002-04-30 | Insite Vision, Incorporated | Methods of ophthalmic administration |
| KR100300527B1 (ko) | 1998-09-03 | 2001-10-27 | 윤덕용 | 밀봉형무선압력측정소자및그제조방법 |
| KR100274842B1 (ko) | 1998-10-01 | 2001-03-02 | 김효근 | 미립구를 이용한 레티노익산의 서방형 약물방출 시스템 |
| US6454787B1 (en) | 1998-12-11 | 2002-09-24 | C. R. Bard, Inc. | Collagen hemostatic foam |
| US6348042B1 (en) | 1999-02-02 | 2002-02-19 | W. Lee Warren, Jr. | Bioactive shunt |
| US6193656B1 (en) | 1999-02-08 | 2001-02-27 | Robert E. Jeffries | Intraocular pressure monitoring/measuring apparatus and method |
| US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US6477410B1 (en) | 2000-05-31 | 2002-11-05 | Biophoretic Therapeutic Systems, Llc | Electrokinetic delivery of medicaments |
| US6217895B1 (en) | 1999-03-22 | 2001-04-17 | Control Delivery Systems | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
| MXPA01010829A (es) | 1999-04-26 | 2003-06-30 | Gmp Vision Solutions Inc | Dispositivo de trabe culotomia y metodo para el tratamiento del glaucoma. |
| US20050119601A9 (en) | 1999-04-26 | 2005-06-02 | Lynch Mary G. | Shunt device and method for treating glaucoma |
| US6558342B1 (en) | 1999-06-02 | 2003-05-06 | Optonol Ltd. | Flow control device, introducer and method of implanting |
| US6306120B1 (en) | 1999-06-07 | 2001-10-23 | Ben Gee Tan | Applicator and method for delivery of mitomycin to eye tissues during glaucoma filtering surgery |
| US6899137B2 (en) | 1999-06-28 | 2005-05-31 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| US20080277007A1 (en) | 1999-06-28 | 2008-11-13 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| US8550119B2 (en) | 1999-06-28 | 2013-10-08 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| CN100402850C (zh) | 1999-06-28 | 2008-07-16 | 加利福尼亚技术学院 | 微型制造的弹性体的阀和泵系统 |
| JP2003508185A (ja) | 1999-08-03 | 2003-03-04 | スミス アンド ネフュー インコーポレーテッド | 埋め込み型制御放出装置 |
| CA2379909C (en) | 1999-08-06 | 2011-01-04 | Board Of Regents, The University Of Texas System | Drug releasing biodegradable fiber implant |
| US7033603B2 (en) | 1999-08-06 | 2006-04-25 | Board Of Regents The University Of Texas | Drug releasing biodegradable fiber for delivery of therapeutics |
| TR200201047T2 (tr) | 1999-10-21 | 2002-07-22 | Alcon, Inc. | İlaç verme vasıtası. |
| US6416777B1 (en) | 1999-10-21 | 2002-07-09 | Alcon Universal Ltd. | Ophthalmic drug delivery device |
| US7943162B2 (en) | 1999-10-21 | 2011-05-17 | Alcon, Inc. | Drug delivery device |
| AU775149B2 (en) | 1999-10-21 | 2004-07-22 | Alcon Inc. | Sub-tenon drug delivery |
| US6331313B1 (en) | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| US6436091B1 (en) | 1999-11-16 | 2002-08-20 | Microsolutions, Inc. | Methods and implantable devices and systems for long term delivery of a pharmaceutical agent |
| KR100855740B1 (ko) | 1999-12-10 | 2008-09-03 | 아이싸이언스 인터벤셔날 코포레이션 | 안 질환의 치료방법 |
| US6939299B1 (en) | 1999-12-13 | 2005-09-06 | Kurt Petersen | Implantable continuous intraocular pressure sensor |
| CA2394968A1 (en) | 1999-12-16 | 2001-06-21 | Alza Corporation | Dosage forms having a barrier layer to laser ablation |
| AU773354B2 (en) | 1999-12-21 | 2004-05-20 | Intarcia Therapeutics, Inc. | Valve for osmotic devices |
| US20050119737A1 (en) | 2000-01-12 | 2005-06-02 | Bene Eric A. | Ocular implant and methods for making and using same |
| WO2001050943A2 (en) | 2000-01-12 | 2001-07-19 | Becton, Dickinson And Company | Systems and methods for reducing intraocular pressure |
| US6589203B1 (en) | 2000-01-26 | 2003-07-08 | Peter Mitrev | Glaucoma drainage device implant |
| US6471666B1 (en) | 2000-02-24 | 2002-10-29 | Steven A. Odrich | Injectable glaucoma device |
| WO2001070705A1 (en) | 2000-03-17 | 2001-09-27 | Alcon, Inc. | 2-acylaminobenzimidazole derivatives for treating glaucoma |
| US20070031473A1 (en) | 2005-08-05 | 2007-02-08 | Peyman Gholam A | Drug delivery system and method |
| US6998137B2 (en) | 2000-04-07 | 2006-02-14 | Macromed, Inc. | Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix |
| US20030060752A1 (en) | 2000-04-14 | 2003-03-27 | Olav Bergheim | Glaucoma device and methods thereof |
| US20040111050A1 (en) | 2000-04-14 | 2004-06-10 | Gregory Smedley | Implantable ocular pump to reduce intraocular pressure |
| US7867186B2 (en) | 2002-04-08 | 2011-01-11 | Glaukos Corporation | Devices and methods for treatment of ocular disorders |
| US7708711B2 (en) | 2000-04-14 | 2010-05-04 | Glaukos Corporation | Ocular implant with therapeutic agents and methods thereof |
| US6638239B1 (en) | 2000-04-14 | 2003-10-28 | Glaukos Corporation | Apparatus and method for treating glaucoma |
| US20050049578A1 (en) | 2000-04-14 | 2005-03-03 | Hosheng Tu | Implantable ocular pump to reduce intraocular pressure |
| US20020143284A1 (en) | 2001-04-03 | 2002-10-03 | Hosheng Tu | Drug-releasing trabecular implant for glaucoma treatment |
| US20050277864A1 (en) | 2000-04-14 | 2005-12-15 | David Haffner | Injectable gel implant for glaucoma treatment |
| US20040175410A1 (en) | 2000-04-26 | 2004-09-09 | Control Delivery Systems, Inc. | Sustained release device and method for ocular delivery of carbonic anhydrase inhibitors |
| US20040115268A1 (en) | 2000-04-26 | 2004-06-17 | Control Delivery Systems, Inc. | Systemic delivery of antiviral agents |
| US20040208910A1 (en) | 2000-04-26 | 2004-10-21 | Control Delivery Systems, Inc. | Sustained release device and method for ocular delivery of adrenergic agents |
| US6375972B1 (en) | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
| CA2408323C (en) | 2000-05-08 | 2012-06-12 | The University Of British Columbia | Drug delivery systems for photodynamic therapy |
| ATE377404T1 (de) | 2000-05-19 | 2007-11-15 | Michael S Berlin | Laserapplikationssystem und methode zur verwendung im auge |
| US9603741B2 (en) | 2000-05-19 | 2017-03-28 | Michael S. Berlin | Delivery system and method of use for the eye |
| JP2003535646A (ja) | 2000-06-19 | 2003-12-02 | グローコス コーポレーション | ステントが装着された小柱シャント及びその方法 |
| KR100355563B1 (ko) | 2000-06-23 | 2002-10-11 | 주식회사 바이오메드랩 | 비등성 혼합물을 이용한 조직공학용 생분해성의 다공성고분자 지지체 및 그의 제조방법 |
| US6692759B1 (en) | 2000-06-28 | 2004-02-17 | The Regents Of The University Of California | Methods for preparing and using implantable substance delivery devices |
| EP1637126B1 (en) | 2000-07-05 | 2016-12-14 | Allergan, Inc. | Methods for treating inflammation of the eye |
| US6726918B1 (en) | 2000-07-05 | 2004-04-27 | Oculex Pharmaceuticals, Inc. | Methods for treating inflammation-mediated conditions of the eye |
| US6629992B2 (en) | 2000-08-04 | 2003-10-07 | Advanced Cardiovascular Systems, Inc. | Sheath for self-expanding stent |
| US7056533B2 (en) | 2000-08-15 | 2006-06-06 | Surmodics, Inc. | Medicament incorporation matrix |
| US6749568B2 (en) | 2000-08-21 | 2004-06-15 | Cleveland Clinic Foundation | Intraocular pressure measurement system including a sensor mounted in a contact lens |
| US6730056B1 (en) | 2000-09-21 | 2004-05-04 | Motorola, Inc. | Eye implant for treating glaucoma and method for manufacturing same |
| AU2001261262A1 (en) | 2000-11-01 | 2002-05-15 | Glaukos Corporation | Glaucoma treatment device |
| EP1550471A1 (en) | 2000-11-29 | 2005-07-06 | Allergan Inc. | Intraocular implants for preventing transplant rejection in the eye |
| US6699493B2 (en) | 2000-11-29 | 2004-03-02 | Oculex Pharmaceuticals, Inc. | Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor |
| US7077859B2 (en) | 2000-12-22 | 2006-07-18 | Avantec Vascular Corporation | Apparatus and methods for variably controlled substance delivery from implanted prostheses |
| WO2002056863A2 (en) | 2000-12-29 | 2002-07-25 | Bausch & Lomb Incorporated | Sustained release drug delivery devices |
| DE60137542D1 (de) | 2001-01-03 | 2009-03-12 | Bausch & Lomb | Wirkstoffabgabevorrichtungen mit verzögerter freisetzung mehrere stoffe enthaltend |
| JP2004522730A (ja) | 2001-01-03 | 2004-07-29 | ボシュ・アンド・ロム・インコーポレイテッド | コーティングされた薬剤コアを備えた徐放薬剤送達装置 |
| EP1347742A1 (en) | 2001-01-03 | 2003-10-01 | Bausch & Lomb Incorporated | Sustained release drug delivery devices with prefabricated permeable plugs |
| DE60219607T2 (de) | 2001-01-09 | 2007-12-27 | Microchips, Inc., Bedford | Flexible mikrochip-vorrichtungen zur ophthalmologischen und anderen applikation |
| US6824521B2 (en) | 2001-01-22 | 2004-11-30 | Integrated Sensing Systems, Inc. | Sensing catheter system and method of fabrication |
| US6991808B2 (en) | 2001-01-26 | 2006-01-31 | Bausch & Lomb Inc. | Process for the production of sustained release drug delivery devices |
| US6758837B2 (en) | 2001-02-08 | 2004-07-06 | Pharmacia Ab | Liquid delivery device and method of use thereof |
| US6571125B2 (en) | 2001-02-12 | 2003-05-27 | Medtronic, Inc. | Drug delivery device |
| US7181287B2 (en) | 2001-02-13 | 2007-02-20 | Second Sight Medical Products, Inc. | Implantable drug delivery device |
| US8060211B2 (en) | 2001-02-13 | 2011-11-15 | Second Sight Medical Products, Inc. | Method of reducing retinal stress caused by an implantable retinal electrode array |
| US6989007B2 (en) | 2001-02-21 | 2006-01-24 | Solx, Inc. | Devices and techniques for treating glaucoma |
| US20040018238A1 (en) | 2001-02-26 | 2004-01-29 | Shukla Atul J | Biodegradable vehicles and delivery systems of biolgically active substances |
| US20050278014A9 (en) | 2001-03-07 | 2005-12-15 | Wolfgang Daum | Stent and method for drug delivery from stents |
| US6713081B2 (en) | 2001-03-15 | 2004-03-30 | The United States Of America As Represented By The Department Of Health And Human Services | Ocular therapeutic agent delivery devices and methods for making and using such devices |
| EP1367968A4 (en) | 2001-03-16 | 2006-12-13 | Glaukos Corp | APPLICATOR AND METHOD FOR SETTING A TRABECULAR SHUNT FOR GLUCKOM TREATMENT |
| ES2304438T3 (es) | 2001-04-07 | 2008-10-16 | Glaukos Corporation | Stent de glaucoma para el tratamiento del glaucoma. |
| US6981958B1 (en) | 2001-05-02 | 2006-01-03 | Glaukos Corporation | Implant with pressure sensor for glaucoma treatment |
| US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
| US6666841B2 (en) | 2001-05-02 | 2003-12-23 | Glaukos Corporation | Bifurcatable trabecular shunt for glaucoma treatment |
| US7488303B1 (en) | 2002-09-21 | 2009-02-10 | Glaukos Corporation | Ocular implant with anchor and multiple openings |
| US20040022853A1 (en) | 2001-04-26 | 2004-02-05 | Control Delivery Systems, Inc. | Polymer-based, sustained release drug delivery system |
| US7678065B2 (en) | 2001-05-02 | 2010-03-16 | Glaukos Corporation | Implant with intraocular pressure sensor for glaucoma treatment |
| WO2002089767A1 (en) | 2001-05-03 | 2002-11-14 | Massachusetts Eye And Ear Infirmary | Implantable drug delivery device and use thereof |
| US6533769B2 (en) | 2001-05-03 | 2003-03-18 | Holmen Joergen | Method for use in cataract surgery |
| US7094225B2 (en) | 2001-05-03 | 2006-08-22 | Glaukos Corporation | Medical device and methods of use of glaucoma treatment |
| US20020176844A1 (en) | 2001-05-11 | 2002-11-28 | Ng Steven Y. | Bioerodible polyorthoesters containing hydrogen bonding groups |
| EP2316394B1 (en) | 2001-06-12 | 2016-11-23 | The Johns Hopkins University | Reservoir device for intraocular drug delivery |
| WO2002103210A1 (en) | 2001-06-15 | 2002-12-27 | Hansford Derek J | Nanopump devices and methods |
| US7592016B2 (en) | 2001-06-28 | 2009-09-22 | Regents Of The University Of California | Methods for preparing and using implantable substance delivery devices |
| DE60217679T2 (de) | 2001-07-23 | 2007-10-25 | Alcon Inc. | Vorrichtung zur freisetzung eines ophthalmischen arzneimittels |
| PT1385452E (pt) | 2001-07-23 | 2006-12-29 | Alcon Inc | Dispositivo de administração de fármacos oftálmicos |
| US7331984B2 (en) | 2001-08-28 | 2008-02-19 | Glaukos Corporation | Glaucoma stent for treating glaucoma and methods of use |
| RU2311892C2 (ru) | 2001-08-29 | 2007-12-10 | КАРВАЛХО Рикардо А. П. ДЕ | Имплантируемая и герметизируемая система для однонаправленной доставки терапевтических препаратов в ткани |
| US7749528B2 (en) | 2001-08-29 | 2010-07-06 | Ricardo Azevedo Pontes De Carvalho | Implantable and sealable medical device for unidirectional delivery of therapeutic agents to tissues |
| IN2014DN10834A (enExample) | 2001-09-17 | 2015-09-04 | Psivida Inc | |
| US20030060873A1 (en) | 2001-09-19 | 2003-03-27 | Nanomedical Technologies, Inc. | Metallic structures incorporating bioactive materials and methods for creating the same |
| AU2002337788A1 (en) | 2001-09-28 | 2003-04-07 | Biovalve Technologies, Inc. | Microneedle with membrane |
| FR2830766B1 (fr) | 2001-10-12 | 2004-03-12 | Optis France Sa | Dispositif de delivrance de medicaments par iontophorese transpalpebrale |
| US20030097151A1 (en) | 2001-10-25 | 2003-05-22 | Smedley Gregory T. | Apparatus and mitochondrial treatment for glaucoma |
| US8425892B2 (en) | 2001-10-29 | 2013-04-23 | Columbia Laboratories, Inc. | Extended, controlled-release pharmaceutical compositions using charged polymers |
| US20030119000A1 (en) | 2001-11-05 | 2003-06-26 | Jon Polansky | Methods to screen and treat individuals with glaucoma or the propensity to develop glaucoma |
| US20080039769A1 (en) | 2001-11-07 | 2008-02-14 | Minu Llc | Method of medical treatment using controlled heat delivery |
| US7163543B2 (en) | 2001-11-08 | 2007-01-16 | Glaukos Corporation | Combined treatment for cataract and glaucoma treatment |
| US6802829B2 (en) | 2001-11-16 | 2004-10-12 | Infinite Vision, Llc | Spray device |
| DE50210569D1 (de) | 2001-11-22 | 2007-09-06 | Eduard Anton Haefliger | Vorrichtung zur durchführung ophtalmologischer eingriffe |
| US7348055B2 (en) | 2001-12-21 | 2008-03-25 | Surmodics, Inc. | Reagent and method for providing coatings on surfaces |
| US20060034929A1 (en) | 2001-12-27 | 2006-02-16 | Brubaker Michael J | Sustained release drug delivery devices with prefabricated permeable plugs |
| GB2399753B (en) | 2002-01-18 | 2006-04-19 | Michael E Snyder | Method of making a sustained release ophthalmological device |
| JP2003210513A (ja) | 2002-01-23 | 2003-07-29 | Nidek Co Ltd | 眼科用治療装置 |
| US6939298B2 (en) | 2002-02-28 | 2005-09-06 | Gmp Vision Solutions, Inc | Device and method for monitoring aqueous flow within the eye |
| US20050069893A1 (en) | 2002-03-01 | 2005-03-31 | Josef Flammer | Diagnostic method for glaucoma |
| US7186232B1 (en) | 2002-03-07 | 2007-03-06 | Glaukoa Corporation | Fluid infusion methods for glaucoma treatment |
| US20060200113A1 (en) | 2002-03-07 | 2006-09-07 | David Haffner | Liquid jet for glaucoma treatment |
| US20060100408A1 (en) | 2002-03-11 | 2006-05-11 | Powell P M | Method for forming contact lenses comprising therapeutic agents |
| EP1482914B1 (en) | 2002-03-11 | 2015-04-22 | Novartis AG | Implantable drug delivery device for the eye |
| TW200304385A (en) | 2002-03-13 | 2003-10-01 | Novartis Ag | Materials containing multiple layers of vesicles |
| US7951155B2 (en) | 2002-03-15 | 2011-05-31 | Glaukos Corporation | Combined treatment for cataract and glaucoma treatment |
| US20030229303A1 (en) | 2002-03-22 | 2003-12-11 | Haffner David S. | Expandable glaucoma implant and methods of use |
| JP4026745B2 (ja) | 2002-03-26 | 2007-12-26 | 財団法人大阪産業振興機構 | 医療用システムおよびその製造方法 |
| JP2003290362A (ja) | 2002-04-02 | 2003-10-14 | Koji Karasawa | 側注管 |
| US20040147870A1 (en) | 2002-04-08 | 2004-07-29 | Burns Thomas W. | Glaucoma treatment kit |
| US9301875B2 (en) | 2002-04-08 | 2016-04-05 | Glaukos Corporation | Ocular disorder treatment implants with multiple opening |
| US20030195438A1 (en) | 2002-04-12 | 2003-10-16 | Petillo Phillip J. | Method and apparatus to treat glaucoma |
| US20040024345A1 (en) | 2002-04-19 | 2004-02-05 | Morteza Gharib | Glaucoma implant with valveless flow bias |
| AU2003217531A1 (en) | 2002-05-02 | 2003-11-17 | Massachusetts Eye And Ear Infirmary | Ocular drug delivery systems and use thereof |
| US8871241B2 (en) | 2002-05-07 | 2014-10-28 | Psivida Us, Inc. | Injectable sustained release delivery devices |
| US20070123767A1 (en) | 2002-05-31 | 2007-05-31 | Valentino Montegrande | Intraocular pressure sensor and method of use |
| US20050159660A1 (en) | 2002-05-31 | 2005-07-21 | Valentino Montegrande | Intraocular pressure sensor |
| US8273366B2 (en) | 2002-06-05 | 2012-09-25 | University Of Florida Research Foundation, Incorporated | Ophthalmic drug delivery system |
| DE60326597D1 (de) | 2002-06-05 | 2009-04-23 | Univ Florida | Ophthalmisches arzneimittelabgabesystem |
| US6945952B2 (en) | 2002-06-25 | 2005-09-20 | Theraject, Inc. | Solid solution perforator for drug delivery and other applications |
| MXPA05000632A (es) | 2002-07-15 | 2005-03-31 | Alcon Inc | Composiciones para implante farmaceuticas, lipofilas, no polimericas para uso intraocular. |
| US20040013702A1 (en) | 2002-07-16 | 2004-01-22 | Glover Eugene G. | Implantable devices for the controlled release of cytotoxic agents |
| DE60325606D1 (de) | 2002-07-19 | 2009-02-12 | Univ Yale | Uveosklerale drainagevorrichtung |
| CA2488393C (en) | 2002-08-08 | 2011-02-01 | Glaukos Corporation | Implantable ocular pump to reduce intraocular pressure |
| WO2004019773A1 (en) | 2002-08-27 | 2004-03-11 | Michigan State University | Implantable microscale pressure sensor system |
| JP4353510B2 (ja) | 2002-09-09 | 2009-10-28 | 株式会社カネカ | 組織再生用支持体及びその製造方法 |
| US7192412B1 (en) | 2002-09-14 | 2007-03-20 | Glaukos Corporation | Targeted stent placement and multi-stent therapy |
| EP1539066B1 (en) | 2002-09-17 | 2012-11-07 | Iscience Surgical Corporation | Apparatus surgical bypass of aqueous humor |
| US20050261641A1 (en) | 2002-09-26 | 2005-11-24 | Warchol Mark P | Method for ophthalmic administration of medicament |
| USRE40722E1 (en) | 2002-09-27 | 2009-06-09 | Surmodics, Inc. | Method and apparatus for coating of substrates |
| US7615010B1 (en) | 2002-10-03 | 2009-11-10 | Integrated Sensing Systems, Inc. | System for monitoring the physiologic parameters of patients with congestive heart failure |
| US7025744B2 (en) | 2002-10-04 | 2006-04-11 | Dsu Medical Corporation | Injection site for male luer or other tubular connector |
| US7131945B2 (en) | 2002-10-16 | 2006-11-07 | California Institute Of Technology | Optically powered and optically data-transmitting wireless intraocular pressure sensor device |
| AU2003291377A1 (en) | 2002-11-06 | 2004-06-03 | Gmp Vision Solutions, Inc. | Storage apparatus for surgical implant device |
| AU2003287666A1 (en) | 2002-11-13 | 2004-06-03 | Control Delivery Systems, Inc. | Systemic delivery of antiviral agents |
| CA2508303C (en) | 2002-12-04 | 2012-10-23 | Santen Pharmaceutical Co., Ltd. | Drug delivery system using subconjunctival depot |
| CA2509382A1 (en) | 2002-12-17 | 2004-07-08 | Todd C. Zion | Stimuli-responsive systems for controlled drug delivery |
| US20050048099A1 (en) | 2003-01-09 | 2005-03-03 | Allergan, Inc. | Ocular implant made by a double extrusion process |
| US20040137059A1 (en) | 2003-01-09 | 2004-07-15 | Thierry Nivaggioli | Biodegradable ocular implant |
| US20040216749A1 (en) | 2003-01-23 | 2004-11-04 | Hosheng Tu | Vasomodulation during glaucoma surgery |
| DK1592407T3 (da) | 2003-01-24 | 2010-04-19 | Psivida Inc | Indretning med depotvirkning og fremgangsmåde til okulær indgivelse af carbonanhydraseinhibitorer |
| WO2004066871A2 (en) | 2003-01-24 | 2004-08-12 | Doheny Retina Institute | Reservoirs with subretinal cannula for subretinal drug delivery |
| US6969514B2 (en) | 2003-02-05 | 2005-11-29 | Soll David B | Method for treating elevated intraocular pressure, including glaucoma |
| US8012115B2 (en) | 2003-02-18 | 2011-09-06 | S.K. Pharmaceuticals, Inc. | Optic nerve implants |
| CA2515568A1 (en) | 2003-02-18 | 2004-09-02 | Hampar Karageozian | Methods and devices for draining fluids and lowering intraocular pressure |
| WO2004073551A2 (en) | 2003-02-18 | 2004-09-02 | Massachusetts Eye And Ear Infirmary | Transscleral drug delivery device and related methods |
| US20040163652A1 (en) | 2003-02-25 | 2004-08-26 | Colin Watson | Condom with restriction band |
| USD490152S1 (en) | 2003-02-28 | 2004-05-18 | Glaukos Corporation | Surgical handpiece |
| WO2005105197A2 (en) | 2003-02-28 | 2005-11-10 | Gmp Vision Solutions, Inc. | Indwelling shunt device and methods for treating glaucoma |
| US7483750B2 (en) | 2003-03-21 | 2009-01-27 | Second Sight Medical Products, Inc. | Transretinal implant and method of implantation |
| US20050208102A1 (en) | 2003-04-09 | 2005-09-22 | Schultz Clyde L | Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases |
| US9216106B2 (en) | 2003-04-09 | 2015-12-22 | Directcontact Llc | Device and method for the delivery of drugs for the treatment of posterior segment disease |
| US8404269B2 (en) | 2003-04-11 | 2013-03-26 | Michael Snyder | Sustained release implantable eye device |
| US8021680B2 (en) | 2003-05-02 | 2011-09-20 | Surmodics, Inc. | Controlled release bioactive agent delivery device |
| US20040225250A1 (en) | 2003-05-05 | 2004-11-11 | Michael Yablonski | Internal shunt and method for treating glaucoma |
| US8012136B2 (en) | 2003-05-20 | 2011-09-06 | Optimyst Systems, Inc. | Ophthalmic fluid delivery device and method of operation |
| ES2523454T3 (es) | 2003-06-16 | 2014-11-26 | Solx, Inc. | Derivación para el tratamiento del glaucoma |
| US20060069340A1 (en) | 2003-06-16 | 2006-03-30 | Solx, Inc. | Shunt for the treatment of glaucoma |
| US20040265356A1 (en) | 2003-06-30 | 2004-12-30 | Bausch & Lomb Incorporated | Drug delivery device |
| WO2005009297A1 (en) | 2003-07-10 | 2005-02-03 | Alcon, Inc. | Ophthalmic drug delivery device |
| US7083802B2 (en) | 2003-07-31 | 2006-08-01 | Advanced Ocular Systems Limited | Treatment of ocular disease |
| WO2005020907A2 (en) | 2003-08-26 | 2005-03-10 | Vista Scientific | Ocular drug delivery device |
| NZ592039A (en) | 2003-08-27 | 2013-03-28 | Ophthotech Corp | Combination therapy for the treatment of ocular neovascular disorders |
| US20050055075A1 (en) | 2003-09-08 | 2005-03-10 | Leonard Pinchuk | Methods for the manufacture of porous prostheses |
| JP2007505932A (ja) | 2003-09-18 | 2007-03-15 | マクサイト, インコーポレイテッド | 経強膜送達 |
| US20050181018A1 (en) | 2003-09-19 | 2005-08-18 | Peyman Gholam A. | Ocular drug delivery |
| US20050196455A1 (en) | 2003-10-27 | 2005-09-08 | Jianbing Chen | Suspension delivery system for the sustained and controlled local release of pharmaceuticals |
| US7291125B2 (en) | 2003-11-14 | 2007-11-06 | Transcend Medical, Inc. | Ocular pressure regulation |
| EP1708780A4 (en) | 2003-11-14 | 2010-10-13 | Medical Instill Tech Inc | DISTRIBUTION DEVICE AND DISTRIBUTION METHOD |
| US20050158356A1 (en) | 2003-11-20 | 2005-07-21 | Angiotech International Ag | Implantable sensors and implantable pumps and anti-scarring agents |
| US20110112352A1 (en) | 2003-12-05 | 2011-05-12 | Pilla Arthur A | Apparatus and method for electromagnetic treatment |
| US20050137538A1 (en) | 2003-12-22 | 2005-06-23 | Bausch & Lomb Incorporated | Drug delivery device |
| CN101912325A (zh) | 2004-01-12 | 2010-12-15 | i科学外科公司 | 一种输送粘性材料的注射器 |
| US7976520B2 (en) | 2004-01-12 | 2011-07-12 | Nulens Ltd. | Eye wall anchored fixtures |
| US9933079B2 (en) | 2004-01-29 | 2018-04-03 | Angiodynamics, Inc. | Stacked membrane for pressure actuated valve |
| US20050250788A1 (en) | 2004-01-30 | 2005-11-10 | Hosheng Tu | Aqueous outflow enhancement with vasodilated aqueous cavity |
| US20060004422A1 (en) | 2004-03-11 | 2006-01-05 | Dirk De Ridder | Electrical stimulation system and method for stimulating tissue in the brain to treat a neurological condition |
| US7513893B2 (en) | 2004-03-12 | 2009-04-07 | Abraham Ebbie Soroudi | Device and method for treatment of eyelid diseases |
| CN100448417C (zh) | 2004-03-26 | 2009-01-07 | 莫尔蒂诺眼科有限公司 | 用于治疗青光眼的眼科植入体 |
| US7654985B2 (en) | 2004-03-30 | 2010-02-02 | Given Imaging Ltd. | Controlled detachment of intra-luminal medical device |
| US20060083772A1 (en) | 2004-04-06 | 2006-04-20 | Dewitt David M | Coating compositions for bioactive agents |
| US20050232972A1 (en) | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
| EP1740239A4 (en) | 2004-04-29 | 2008-12-03 | Iscience Interventional Corp | DEVICE AND METHOD FOR THE SURGICAL REINFORCEMENT OF THE DRAINAGE OF AQUEOUS HUMOR |
| US20100173866A1 (en) | 2004-04-29 | 2010-07-08 | Iscience Interventional Corporation | Apparatus and method for ocular treatment |
| US20080058704A1 (en) | 2004-04-29 | 2008-03-06 | Michael Hee | Apparatus and Method for Ocular Treatment |
| US8722097B2 (en) | 2004-04-30 | 2014-05-13 | Allergan, Inc. | Oil-in-water method for making polymeric implants containing a hypotensive lipid |
| US8147865B2 (en) | 2004-04-30 | 2012-04-03 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
| US8455656B2 (en) | 2004-04-30 | 2013-06-04 | Allergan, Inc. | Kinase inhibitors |
| US20050244500A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Intravitreal implants in conjuction with photodynamic therapy to improve vision |
| US20050244469A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Extended therapeutic effect ocular implant treatments |
| US8425929B2 (en) | 2004-04-30 | 2013-04-23 | Allergan, Inc. | Sustained release intraocular implants and methods for preventing retinal dysfunction |
| US7771742B2 (en) | 2004-04-30 | 2010-08-10 | Allergan, Inc. | Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods |
| AU2005240078A1 (en) | 2004-04-30 | 2005-11-17 | Allergan, Inc. | Retinoid-containing sustained release intraocular drug delivery systems and related methods of manufacturing |
| US20070212395A1 (en) | 2006-03-08 | 2007-09-13 | Allergan, Inc. | Ocular therapy using sirtuin-activating agents |
| US20050244465A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Drug delivery systems and methods for treatment of an eye |
| US8673341B2 (en) | 2004-04-30 | 2014-03-18 | Allergan, Inc. | Intraocular pressure reduction with intracameral bimatoprost implants |
| BRPI0510485A (pt) | 2004-04-30 | 2007-11-13 | Allergan Inc | implantes inibidores de tirosina cinase intravìtreos biodegradáveis |
| US20050244472A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Intraocular drug delivery systems containing excipients with reduced toxicity and related methods |
| US8685435B2 (en) | 2004-04-30 | 2014-04-01 | Allergan, Inc. | Extended release biodegradable ocular implants |
| AU2005247122C1 (en) | 2004-04-30 | 2012-02-02 | Eyegate Pharma S.A. | Irritation-reducing ocular iontophoretic device |
| US20050244458A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Sustained release intraocular implants and methods for treating ocular neuropathies |
| US20070059336A1 (en) | 2004-04-30 | 2007-03-15 | Allergan, Inc. | Anti-angiogenic sustained release intraocular implants and related methods |
| US8119154B2 (en) | 2004-04-30 | 2012-02-21 | Allergan, Inc. | Sustained release intraocular implants and related methods |
| US7799336B2 (en) | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
| US20050244461A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Controlled release drug delivery systems and methods for treatment of an eye |
| WO2005121735A2 (en) | 2004-06-07 | 2005-12-22 | California Institute Of Technology | Implantable mechanical pressure sensor and method of manufacturing the same |
| US8128954B2 (en) | 2004-06-07 | 2012-03-06 | California Institute Of Technology | Biodegradable drug-polymer delivery system |
| EP1604697A1 (en) | 2004-06-09 | 2005-12-14 | J.A.C.C. GmbH | Implantable device |
| WO2006002366A2 (en) | 2004-06-24 | 2006-01-05 | Surmodics, Inc. | Biodegradable ocular devices, methods and systems |
| WO2006014484A2 (en) | 2004-07-02 | 2006-02-09 | Surmodics, Inc. | Methods and devices for the treatment of ocular conditions |
| AU2005269988B2 (en) | 2004-07-02 | 2012-02-02 | Mati Therapeutics Inc. | Treatment medium delivery device and methods for delivery |
| AU2005271700B2 (en) | 2004-07-12 | 2010-11-11 | Allergan, Inc. | Opthalmic compositions and methods for treating ophthalmic conditions |
| US20060020253A1 (en) | 2004-07-26 | 2006-01-26 | Prescott Anthony D | Implantable device having reservoir with controlled release of medication and method of manufacturing the same |
| US7117870B2 (en) | 2004-07-26 | 2006-10-10 | Clarity Corporation | Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same |
| WO2006015016A2 (en) | 2004-07-30 | 2006-02-09 | Massachusetts Eye And Ear Infirmary | Photodynamic therapy and compositions for treating ocular glaucoma |
| US20060032507A1 (en) | 2004-08-11 | 2006-02-16 | Hosheng Tu | Contrast-enhanced ocular imaging |
| US7402156B2 (en) | 2004-09-01 | 2008-07-22 | Alcon, Inc. | Counter pressure device for ophthalmic drug delivery |
| US20060084952A1 (en) | 2004-09-03 | 2006-04-20 | Pallikaris Ioannis G | Device for the irradiation of the ciliary body of the eye |
| US7709049B2 (en) | 2004-09-10 | 2010-05-04 | Surmodics, Inc. | Methods, devices, and coatings for controlled active agent release |
| US20070292523A1 (en) | 2004-09-27 | 2007-12-20 | Joey Moodley | Dihydropyrimidine Formulations |
| US20060067978A1 (en) | 2004-09-29 | 2006-03-30 | Bausch & Lomb Incorporated | Process for preparing poly(vinyl alcohol) drug delivery devices |
| US20060067980A1 (en) | 2004-09-30 | 2006-03-30 | Bausch & Lomb Incorporated | Capsule for encasing tablets for surgical insertion into the human body |
| US20080038316A1 (en) | 2004-10-01 | 2008-02-14 | Wong Vernon G | Conveniently implantable sustained release drug compositions |
| CA2582374A1 (en) | 2004-10-04 | 2006-04-20 | Qlt Usa, Inc. | Ocular delivery of polymeric delivery formulations |
| GB0422525D0 (en) | 2004-10-11 | 2004-11-10 | Luebcke Peter | Dermatological compositions and methods |
| US7226435B2 (en) | 2004-10-14 | 2007-06-05 | Alcon, Inc. | Drug delivery device |
| US20060089590A1 (en) | 2004-10-27 | 2006-04-27 | John Higuchi | Methods and devices for sustained in-vivo release of an active agent |
| US7958840B2 (en) | 2004-10-27 | 2011-06-14 | Surmodics, Inc. | Method and apparatus for coating of substrates |
| EP1814519A1 (en) | 2004-11-16 | 2007-08-08 | Université de Liège | Active substance delivery system comprising a hydrogel atrix and microcarriers |
| US20060173397A1 (en) | 2004-11-23 | 2006-08-03 | Hosheng Tu | Ophthalmology implants and methods of manufacture |
| DE602005026978D1 (de) | 2004-11-23 | 2011-04-28 | Timothy L Lee | Medizinische vorrichtung zur temperaturregelung und behandlung des auges sowie des umgebenden gewebes |
| CA2588449A1 (en) | 2004-11-24 | 2006-06-01 | Therakine Corporation | An implant for intraocular drug delivery |
| US7837644B2 (en) | 2004-12-03 | 2010-11-23 | Innfocus, Llc | Glaucoma implant device |
| US20070118065A1 (en) | 2004-12-03 | 2007-05-24 | Leonard Pinchuk | Glaucoma Implant Device |
| US20060135918A1 (en) | 2004-12-22 | 2006-06-22 | Bausch & Lomb Incorporated | Reusable drug delivery device |
| MX2007006735A (es) | 2004-12-22 | 2007-07-25 | Alcon Inc | Dispositivo para entregar farmaco oftalmico. |
| MX2007009417A (es) | 2005-02-04 | 2007-08-17 | Univ Auburn | Sistema de suministro de farmaco de contacto. |
| US8663639B2 (en) | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
| CA2597590A1 (en) | 2005-02-09 | 2006-08-17 | Macusight, Inc. | Formulations for ocular treatment |
| CA2602525A1 (en) | 2005-03-21 | 2006-09-28 | Macusight, Inc. | Drug delivery systems for treatment of diseases or conditions |
| CA2601864A1 (en) | 2005-04-08 | 2006-10-19 | Surmodics, Inc. | Sustained release implants and methods for subretinal delivery of bioactive agents to treat or prevent retinal disease |
| ES2367921T3 (es) | 2005-04-18 | 2011-11-10 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Procedimiento y dispositivos para el suministro de un producto terapéutico a la esfera ocular de un paciente. |
| US7931909B2 (en) | 2005-05-10 | 2011-04-26 | Allergan, Inc. | Ocular therapy using alpha-2 adrenergic receptor compounds having enhanced anterior clearance rates |
| US20060258994A1 (en) | 2005-05-12 | 2006-11-16 | Avery Robert L | Implantable delivery device for administering pharmacological agents to an internal portion of a body |
| US20060292222A1 (en) | 2005-06-21 | 2006-12-28 | Matthew Jonasse | Drug delivery device having zero or near zero-order release kinetics |
| US20070021653A1 (en) | 2005-06-27 | 2007-01-25 | Lars-Olof Hattenbach | Device for the injection of drugs into microvessels |
| ES2691646T3 (es) | 2005-07-15 | 2018-11-28 | Micell Technologies, Inc. | Revestimientos poliméricos que contienen polvo de fármaco de morfología controlada |
| BRPI0615974A2 (pt) | 2005-07-27 | 2011-05-31 | University Of Florida Research Foundation, Inc., | uso de choque térmico para tratar uma doença ocular em um indivìduo, método para recrutar uma célula-tronco para um tecido ocular de um indivìduo com necessidade da mesma, uso de choque térmico para tratar uma doença ou um distúrbio ocular em um indivìduo com necessidade do mesmo, uso de choque térmico para regenerar a retina em um indivìduo com necessidade do mesmo, uso de choque térmico para reparar os danos ao epitélio pgmentar da retina em um indivìduo com necessidade do mesmo, uso de choque térmico para tratar a degeneração macular em um indivìduo com necessidade do mesmo, composição farmacêutica para o recrutamento de células-tronco, composição farmacêutica para recrutamento de células-tronco em um tecido ocular, kit e método para identificar um agente que aumenta o recrutamento de células-tronco em um tecido ocular |
| US8663673B2 (en) | 2005-07-29 | 2014-03-04 | Surmodics, Inc. | Devices, articles, coatings, and methods for controlled active agent release or hemocompatibility |
| US20070038174A1 (en) | 2005-08-09 | 2007-02-15 | Hopkins Mark A | Ophthalmic injector system |
| US7261529B2 (en) | 2005-09-07 | 2007-08-28 | Southwest Research Institute | Apparatus for preparing biodegradable microparticle formulations containing pharmaceutically active agents |
| US20070212397A1 (en) | 2005-09-15 | 2007-09-13 | Roth Daniel B | Pharmaceutical delivery device and method for providing ocular treatment |
| CA2621595A1 (en) | 2005-09-21 | 2007-04-12 | Surmodics, Inc. | Coatings and articles including natural biodegradable polysaccharides |
| EP1928407B1 (en) | 2005-09-21 | 2009-03-18 | Aston University | Chronotherapeutic ocular delivery system comprising a combination of prostaglandin and a beta-blocker for treating primary glaucoma |
| US20080167600A1 (en) | 2005-09-26 | 2008-07-10 | Peyman Gholam A | Device for delivery of an agent to the eye and other sites |
| WO2007041584A2 (en) | 2005-10-03 | 2007-04-12 | Combinatorx, Incorporated | Implantable sensors, implantable pumps, and anti-scarring drug combinations |
| US8168584B2 (en) | 2005-10-08 | 2012-05-01 | Potentia Pharmaceuticals, Inc. | Methods of treating age-related macular degeneration by compstatin and analogs thereof |
| US20090082321A1 (en) | 2007-09-21 | 2009-03-26 | Allergan, Inc. | Steroid containing drug delivery systems |
| MX339797B (es) | 2005-10-18 | 2016-06-10 | Allergan Inc | Terapia ocular que usa derivados glucocorticoides que penetran selectivamente los tejidos del segmento posterior. |
| TW200733993A (en) | 2005-11-03 | 2007-09-16 | Reseal Internat Ltd Partnership | Continuously sealing one way valve assembly and fluid delivery system and formulations for use therein |
| US8099162B2 (en) | 2005-11-29 | 2012-01-17 | Eyegate Pharma, S.A.S. | Ocular iontophoresis device |
| US20080177220A1 (en) | 2006-01-06 | 2008-07-24 | The Curators Of The University Of Missouri | Ultrasound-Mediated Transcleral Drug Delivery |
| EP1973493A2 (en) | 2006-01-12 | 2008-10-01 | Massachusetts Institute of Technology | Biodegradable elastomers |
| JP5388582B2 (ja) | 2006-01-17 | 2014-01-15 | トランセンド・メディカル・インコーポレイテッド | 薬剤投与処置装置 |
| PT2526910E (pt) | 2006-01-17 | 2015-11-18 | Transcend Medical Inc | Dispositivo para tratamento de glaucoma |
| US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
| EP2316505B1 (en) | 2006-03-14 | 2017-01-18 | University Of Southern California | Mems device for delivery of therapeutic agents |
| KR20090006153A (ko) | 2006-03-31 | 2009-01-14 | 큐엘티 플러그 딜리버리, 인코포레이티드 | 비루관계에 대한 약물 전달 방법, 구조, 및 조성물 |
| EP2012654A2 (en) | 2006-04-18 | 2009-01-14 | Cascade Ophthalmics | Intraocular pressure attenuation device |
| AU2007243306B2 (en) | 2006-04-26 | 2013-03-21 | Eastern Virginia Medical School | Systems and methods for monitoring and controlling internal pressure of an eye or body part |
| US20070293807A1 (en) | 2006-05-01 | 2007-12-20 | Lynch Mary G | Dual drainage pathway shunt device and method for treating glaucoma |
| US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
| US8216603B2 (en) | 2006-05-04 | 2012-07-10 | Herbert Edward Kaufman | Method, device, and system for delivery of therapeutic agents to the eye |
| US20070260203A1 (en) | 2006-05-04 | 2007-11-08 | Allergan, Inc. | Vasoactive agent intraocular implant |
| US20070270768A1 (en) | 2006-05-17 | 2007-11-22 | Bruno Dacquay | Mechanical Linkage Mechanism For Ophthalmic Injection Device |
| US7674243B2 (en) | 2006-05-17 | 2010-03-09 | Alcon Inc. | Ophthalmic injection device using piezoelectric array |
| US7862540B2 (en) | 2006-05-17 | 2011-01-04 | Alcon Research, Ltd. | Ophthalmic injection device using shape memory alloy |
| US20070270750A1 (en) | 2006-05-17 | 2007-11-22 | Alcon, Inc. | Drug delivery device |
| US20070268340A1 (en) | 2006-05-17 | 2007-11-22 | Bruno Dacquay | Ophthalmic Injection System and Method Using Piezoelectric Array |
| US7815603B2 (en) | 2006-05-17 | 2010-10-19 | Alcon Research, Ltd. | Ophthalmic injection method |
| US7811252B2 (en) | 2006-05-17 | 2010-10-12 | Alcon Research, Ltd. | Dosage control device |
| US7887521B2 (en) | 2006-05-17 | 2011-02-15 | Alcon Research, Ltd. | Ophthalmic injection system |
| WO2007146342A2 (en) | 2006-06-12 | 2007-12-21 | Ivivi Technologies, Inc. | Electromagnetism for prophylaxis and opthalmic tissue repair |
| US20070293873A1 (en) | 2006-06-19 | 2007-12-20 | Allergan, Inc. | Apparatus and methods for implanting particulate ocular implants |
| US7458953B2 (en) | 2006-06-20 | 2008-12-02 | Gholam A. Peyman | Ocular drainage device |
| US9474645B2 (en) | 2006-06-21 | 2016-10-25 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
| US20080045911A1 (en) | 2006-06-21 | 2008-02-21 | Borgia Maureen J | Punctal plugs for the delivery of active agents |
| US20070298073A1 (en) | 2006-06-23 | 2007-12-27 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
| US8802128B2 (en) | 2006-06-23 | 2014-08-12 | Allergan, Inc. | Steroid-containing sustained release intraocular implants and related methods |
| AU2007269259B2 (en) | 2006-06-30 | 2012-05-31 | Aquesys Inc. | Methods, systems and apparatus for relieving pressure in an organ |
| US20080152694A1 (en) | 2006-07-20 | 2008-06-26 | Neurosystec Corporation | Devices, Systems and Methods for Ophthalmic Drug Delivery |
| US20080057103A1 (en) | 2006-08-21 | 2008-03-06 | Wouter Roorda | Methods of using medical devices for controlled drug release |
| US20080086101A1 (en) | 2006-08-25 | 2008-04-10 | David Freilich | Ophthalmic insert |
| EP2063872B2 (en) | 2006-08-30 | 2019-12-04 | Jagotec AG | Controlled release oral dosage formulations comprising a core and one or more barrier layers |
| WO2008030958A2 (en) | 2006-09-06 | 2008-03-13 | Innfocus, Llc | Apparatus, methods and devices for treatment of ocular disorders |
| US20080075753A1 (en) | 2006-09-25 | 2008-03-27 | Chappa Ralph A | Multi-layered coatings and methods for controlling elution of active agents |
| US20080125712A1 (en) | 2006-09-26 | 2008-05-29 | Alcon Manufacturing, Ltd. | Ophthalmic injection system |
| US20080097379A1 (en) | 2006-09-26 | 2008-04-24 | Alcon Manufacturing, Ltd. | Ophthalmic injection method |
| US20080097390A1 (en) | 2006-09-27 | 2008-04-24 | Alcon Manufacturing, Ltd. | Spring actuated delivery system |
| US20080081064A1 (en) | 2006-09-28 | 2008-04-03 | Surmodics, Inc. | Implantable Medical Device with Apertures for Delivery of Bioactive Agents |
| US20080089923A1 (en) | 2006-09-29 | 2008-04-17 | Burkstrand Michael J | Biodegradable ocular implants and methods for treating ocular conditions |
| US20100098735A1 (en) | 2006-10-05 | 2010-04-22 | Rajesh Jain | Injectable depot compositions and its process of preparation |
| US7535991B2 (en) | 2006-10-16 | 2009-05-19 | Oraya Therapeutics, Inc. | Portable orthovoltage radiotherapy |
| US20080281292A1 (en) | 2006-10-16 | 2008-11-13 | Hickingbotham Dyson W | Retractable Injection Port |
| US7620147B2 (en) | 2006-12-13 | 2009-11-17 | Oraya Therapeutics, Inc. | Orthovoltage radiotherapy |
| US9022970B2 (en) | 2006-10-16 | 2015-05-05 | Alcon Research, Ltd. | Ophthalmic injection device including dosage control device |
| JP2010506679A (ja) | 2006-10-16 | 2010-03-04 | アルコン リサーチ, リミテッド | 眼科用医療デバイスのために一体化された温度制御デバイスを備えるセラミック・チャンバ |
| US8039010B2 (en) | 2006-11-03 | 2011-10-18 | Allergan, Inc. | Sustained release intraocular drug delivery systems comprising a water soluble therapeutic agent and a release modifier |
| US7494487B2 (en) | 2006-11-03 | 2009-02-24 | Mobius Therapeutics, Llc | Apparatus and method for application of a pharmaceutical to the tympanic membrane for photodynamic laser myringotomy |
| US20080114076A1 (en) | 2006-11-09 | 2008-05-15 | Alcon Manufacturing Ltd. | Punctal plug comprising a water-insoluble polymeric matrix |
| AU2007319383A1 (en) | 2006-11-10 | 2008-05-22 | Glaukos Corporation | Uveoscleral shunt and methods for implanting same |
| US20080138408A1 (en) | 2006-11-13 | 2008-06-12 | Siddharth Venkatesh | Drug delivery system and method |
| US8143410B2 (en) | 2006-11-16 | 2012-03-27 | Allergan, Inc. | Kinase inhibitors |
| US20090036768A1 (en) | 2006-11-17 | 2009-02-05 | Boston Scientific Scimed, Inc. | Medical devices |
| WO2008070479A2 (en) | 2006-12-01 | 2008-06-12 | Allergan, Inc. | Method for determining optimum intraocular locations for drug delivery systems |
| US8969415B2 (en) | 2006-12-01 | 2015-03-03 | Allergan, Inc. | Intraocular drug delivery systems |
| US8617143B2 (en) | 2006-12-07 | 2013-12-31 | The Regents Of The University Of California | Therapeutic agent delivery systems and devices |
| US20080140024A1 (en) | 2006-12-08 | 2008-06-12 | Yoseph Yaacobi | Drug delivery device |
| US20080145405A1 (en) | 2006-12-15 | 2008-06-19 | Kunzler Jay F | Drug delivery devices |
| US20080147021A1 (en) | 2006-12-15 | 2008-06-19 | Jani Dharmendra M | Drug delivery devices |
| CA2670944A1 (en) | 2006-12-18 | 2008-06-26 | Alcon Research, Ltd. | Devices and methods for ophthalmic drug delivery |
| US20080181928A1 (en) | 2006-12-22 | 2008-07-31 | Miv Therapeutics, Inc. | Coatings for implantable medical devices for liposome delivery |
| CA2674076A1 (en) | 2006-12-26 | 2008-07-10 | Qlt Plug Delivery, Inc. | Drug delivery implants for inhibition of optical defects |
| DE102007004906A1 (de) | 2007-01-25 | 2008-07-31 | Universität Rostock | Augenimplantat |
| UY30883A1 (es) | 2007-01-31 | 2008-05-31 | Alcon Res | Tapones punctales y metodos de liberacion de agentes terapeuticos |
| US9144516B2 (en) | 2007-02-08 | 2015-09-29 | Sharpsight B.V. | Device for intraocular administration of a substance, for example a medication, into a human or animal eye by means of a hypodermic needle |
| JP4799444B2 (ja) | 2007-02-26 | 2011-10-26 | パナソニック株式会社 | シミュレーションシステム |
| TW200840554A (en) | 2007-02-28 | 2008-10-16 | Alcon Inc | Coated medical implants and lenses |
| US7561085B2 (en) | 2007-03-21 | 2009-07-14 | Honeywell International Inc. | Systems and methods for improving data converters |
| US8580789B2 (en) | 2007-04-02 | 2013-11-12 | The Cleveland Clinic Foundation | Treating glaucoma |
| US20090148498A1 (en) | 2007-05-14 | 2009-06-11 | Sustained Nano Systems Llc | Controlled release implantable dispensing device and method |
| US8071119B2 (en) | 2007-05-14 | 2011-12-06 | Sustained Nano Systems Llc | Controlled release implantable dispensing device and method |
| US20080286338A1 (en) | 2007-05-15 | 2008-11-20 | Boston Foundation For Sight | Drug delivery system with scleral lens |
| US8231892B2 (en) | 2007-05-24 | 2012-07-31 | Allergan, Inc. | Biodegradable drug delivery system |
| US20080306429A1 (en) | 2007-06-07 | 2008-12-11 | Shields Milton B | Uveoscleral drainage device |
| EP2178502A2 (en) | 2007-06-21 | 2010-04-28 | Yale University | Sustained delivery of drugs from biodegradable polymeric microparticles |
| WO2009009688A1 (en) | 2007-07-10 | 2009-01-15 | Osteotech, Inc. | Delivery system |
| JP5328788B2 (ja) | 2007-07-17 | 2013-10-30 | トランセンド・メディカル・インコーポレイテッド | ヒドロゲルの拡張能力を備えた眼内植込み体 |
| US20090036827A1 (en) | 2007-07-31 | 2009-02-05 | Karl Cazzini | Juxtascleral Drug Delivery and Ocular Implant System |
| US8366652B2 (en) | 2007-08-17 | 2013-02-05 | The Invention Science Fund I, Llc | Systems, devices, and methods including infection-fighting and monitoring shunts |
| US8475374B2 (en) | 2007-08-23 | 2013-07-02 | Purdue Research Foundation | Intra-occular pressure sensor |
| US8303536B2 (en) | 2007-08-30 | 2012-11-06 | Sunstorm Research Corp. | Implantable delivery device |
| US8075909B2 (en) | 2007-09-04 | 2011-12-13 | University Of Florida Research Foundation, Incorporated | Contact lens based bioactive agent delivery system |
| AU2008300013A1 (en) | 2007-09-07 | 2009-03-19 | Qlt Inc. | Drug cores for sustained release of therapeutic agents |
| BRPI0817082A2 (pt) | 2007-09-07 | 2015-03-31 | Qlt Plug Delivery Inc | Implantes lacrimais e métodos relacionados |
| US9011361B2 (en) | 2007-09-07 | 2015-04-21 | Mati Therapeutics Inc. | Lacrimal implant detection |
| US7740604B2 (en) | 2007-09-24 | 2010-06-22 | Ivantis, Inc. | Ocular implants for placement in schlemm's canal |
| US8480638B2 (en) | 2007-10-04 | 2013-07-09 | Aciont, Inc. | Intraocular iontophoretic device and associated methods |
| TWI451862B (zh) * | 2007-10-09 | 2014-09-11 | Alcon Res Ltd | 用於眼睛注射的熱係數驅動藥丸尺寸 |
| US8109920B2 (en) | 2007-10-31 | 2012-02-07 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| GB0722484D0 (en) | 2007-11-15 | 2007-12-27 | Ucl Business Plc | Solid compositions |
| US20090130017A1 (en) | 2007-11-19 | 2009-05-21 | Searete Llc | Targeted short-lived drug delivery |
| US20090143752A1 (en) | 2007-12-03 | 2009-06-04 | Higuchi John W | Passive intraocular drug delivery devices and associated methods |
| EP2242464B2 (en) | 2007-12-20 | 2017-03-01 | University Of Southern California | Apparatus for delivering therapeutic agents |
| US20090162417A1 (en) | 2007-12-21 | 2009-06-25 | Cook Incorporated | Drug eluting ocular conformer |
| EP2676701B1 (en) | 2008-01-07 | 2016-03-30 | Salutaris Medical Devices, Inc. | Devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye |
| US20090177182A1 (en) | 2008-01-09 | 2009-07-09 | Hickingbotham Dyson W | Glass Drug Chamber For Automated Ophthalmic Injection Device |
| WO2009092067A2 (en) | 2008-01-18 | 2009-07-23 | Neurosystec Corporation | Valveless impedance pump drug delivery systems |
| WO2009097468A2 (en) | 2008-01-29 | 2009-08-06 | Kliman Gilbert H | Drug delivery devices, kits and methods therefor |
| EP2254536A2 (en) | 2008-02-18 | 2010-12-01 | QLT Plug Delivery, Inc. | Lacrimal implants and related methods |
| US20090274877A1 (en) | 2008-03-11 | 2009-11-05 | Edwin Chan | Stimuli-responsive surfaces |
| TNSN08110A1 (en) | 2008-03-11 | 2009-07-14 | Rekik Raouf Dr | Drug delivery to the anterior and posterior segment of the eye from drops |
| WO2009120361A2 (en) | 2008-03-28 | 2009-10-01 | Surmodics, Inc. | Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery |
| WO2009128944A2 (en) | 2008-04-18 | 2009-10-22 | Surmodics, Inc. | Coating systems for the controlled delivery of hydrophilic bioactive agents |
| TWI542338B (zh) | 2008-05-07 | 2016-07-21 | 壯生和壯生視覺關懷公司 | 用於活性劑之控制釋放的眼用裝置 |
| MX2010012212A (es) | 2008-05-08 | 2011-09-27 | Minipumps Llc | Dispositivos implantables para suministro de fármacos, y áparato y métodos para llenar los dispositivos. |
| US9162024B2 (en) | 2008-05-08 | 2015-10-20 | Minipumps, Llc | Drug-delivery pumps and methods of manufacture |
| CN104353150A (zh) | 2008-05-08 | 2015-02-18 | 迷你泵有限责任公司 | 可植入泵和用于可植入泵的插管 |
| EP2276492A2 (en) | 2008-05-09 | 2011-01-26 | QLT Plug Delivery, Inc. | Sustained release delivery of active agents to treat glaucoma and ocular hypertension |
| US9095404B2 (en) | 2008-05-12 | 2015-08-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| US8702995B2 (en) | 2008-05-27 | 2014-04-22 | Dober Chemical Corp. | Controlled release of microbiocides |
| US8894602B2 (en) | 2010-09-17 | 2014-11-25 | Johnson & Johnson Vision Care, Inc. | Punctal plugs with directional release |
| US20100274224A1 (en) | 2008-07-08 | 2010-10-28 | Qlt Plug Delivery, Inc. | Lacrimal implant body including comforting agent |
| WO2010036966A1 (en) | 2008-09-26 | 2010-04-01 | The Cleveland Clinic Foundation | Apparatus and method for delivering a therapeutic agent to ocular tissue |
| US8221353B2 (en) | 2008-10-21 | 2012-07-17 | KMG Pharma, Inc | Intravitreal injection device and system |
| US7678078B1 (en) | 2008-10-21 | 2010-03-16 | KMG Pharma LLC | Intravitreal injection device, system and method |
| US20110125090A1 (en) | 2008-11-13 | 2011-05-26 | Peyman Gholam A | Ophthalmic drug delivery system and method |
| US20100119519A1 (en) | 2008-11-13 | 2010-05-13 | Peyman Gholam A | Ophthalmic drug delivery system and method |
| CA2743772C (en) | 2008-11-14 | 2015-06-30 | The Board Of Regents Of The University Of Texas System | Nanochanneled device and related methods |
| US9095506B2 (en) | 2008-11-17 | 2015-08-04 | Allergan, Inc. | Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof |
| JP2012509737A (ja) | 2008-11-26 | 2012-04-26 | サーモディクス,インコーポレイティド | 埋め込み式の眼薬送達器具および眼薬送達方法 |
| WO2010065970A1 (en) | 2008-12-05 | 2010-06-10 | Ivantis, Inc. | Methods and apparatus for delivering ocular implants into the eye |
| EP2962682B1 (en) | 2008-12-11 | 2018-03-28 | Massachusetts Institute Of Technology | Method of making a contact lens drug delivery device |
| US20100152676A1 (en) | 2008-12-16 | 2010-06-17 | Alcon Research, Ltd. | Drug Loading Through Plunger |
| US8070290B2 (en) | 2008-12-17 | 2011-12-06 | Glaukos Corporation | Gonioscope for improved viewing |
| US20120257167A1 (en) | 2008-12-17 | 2012-10-11 | Glaukos Corporation | Gonioscope for improved viewing |
| US20100158980A1 (en) | 2008-12-18 | 2010-06-24 | Casey Kopczynski | Drug delivery devices for delivery of therapeutic agents |
| US20100160870A1 (en) | 2008-12-18 | 2010-06-24 | Alcon Research, Ltd. | Two Piece Housing For Drug Loading |
| WO2010078428A1 (en) | 2008-12-30 | 2010-07-08 | Optimyst Systems, Inc. | Ophthalmic fluid delivery system |
| WO2010078063A1 (en) | 2009-01-02 | 2010-07-08 | Alcon Research, Ltd. | In-situ refillable ophthalmic implant |
| EP2548538B1 (en) | 2009-01-28 | 2020-04-01 | Alcon Inc. | Implantation systems for ocular implants with stiffness qualities |
| CA2757037C (en) | 2009-01-29 | 2019-08-06 | Forsight Vision4, Inc. | Posterior segment drug delivery |
| US9282891B2 (en) | 2009-01-30 | 2016-03-15 | Sundaraja Sitaram Iyengar | Monitoring intra ocular pressure using pattern and color changes |
| WO2010093662A2 (en) | 2009-02-10 | 2010-08-19 | Psivida Us, Inc. | Ocular trocar assembly |
| US20100204325A1 (en) | 2009-02-11 | 2010-08-12 | Allergan, Inc. | Valproic acid drug delivery systems and intraocular therapeutic uses thereof |
| WO2010093950A1 (en) | 2009-02-12 | 2010-08-19 | Osteotech, Inc. | Delivery system cartridge |
| US9636255B2 (en) | 2009-02-13 | 2017-05-02 | Dose Medical Corporation | Uveoscleral drug delivery implant and methods for implanting the same |
| US8603051B2 (en) | 2009-02-17 | 2013-12-10 | Kuvio, Inc. | Implantable drug delivery devices |
| US20100225061A1 (en) | 2009-03-09 | 2010-09-09 | Bath David L | System and method for gaming with an engagable projectile |
| CA2792484C (en) | 2009-03-12 | 2017-10-31 | Delpor, Inc. | Implantable device for long-term delivery of drugs |
| WO2010105130A2 (en) | 2009-03-13 | 2010-09-16 | Vista Scientific Llc | Opthalmic drug delivery system and applications |
| US20100239635A1 (en) | 2009-03-23 | 2010-09-23 | Micell Technologies, Inc. | Drug delivery medical device |
| US20100247606A1 (en) | 2009-03-25 | 2010-09-30 | Allergan, Inc. | Intraocular sustained release drug delivery systems and methods for treating ocular conditions |
| TWI495459B (zh) | 2009-03-31 | 2015-08-11 | Johnson & Johnson Vision Care | 淚管塞(二) |
| US8337393B2 (en) | 2009-04-03 | 2012-12-25 | Transcend Medical, Inc. | Ocular implant delivery systems and methods |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| JP5937004B2 (ja) | 2009-05-18 | 2016-06-22 | ドーズ メディカル コーポレーションDose Medical Corporation | 薬剤溶出眼内インプラント |
| WO2015073571A1 (en) | 2013-11-15 | 2015-05-21 | Dose Medical Corporation | Ocular implants configured to store and release stable drug formulations |
| US12478503B2 (en) | 2009-05-18 | 2025-11-25 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| EP2437684B1 (en) | 2009-06-03 | 2022-06-15 | ForSight Vision5, Inc. | Anterior segment drug delivery |
| WO2011010310A1 (en) | 2009-07-22 | 2011-01-27 | Advanced Ophthalmic Pharma Ltd. | Device for applying an ophthalmic medicament mist |
| CN102573813B (zh) | 2009-08-18 | 2013-11-06 | 国立大学法人东北大学 | 持续药物传递系统 |
| US8808257B2 (en) | 2009-08-31 | 2014-08-19 | Johnson & Johnson Vision Care, Inc. | Methods and apparatus for pulsatile release of medicaments from a punctal plug |
| MX2012002591A (es) | 2009-09-03 | 2012-04-02 | Allergan Inc | Compuestos como moduladores de tirosina cinasas. |
| US9174065B2 (en) | 2009-10-12 | 2015-11-03 | Kona Medical, Inc. | Energetic modulation of nerves |
| WO2011050250A1 (en) | 2009-10-22 | 2011-04-28 | On Demand Therapeutics, Inc. | Visual indication of rupture of drug reservoir |
| US20110129516A1 (en) | 2009-10-30 | 2011-06-02 | Aton Pharma, Inc. | Ocular drug delivery devices |
| EP2496304A4 (en) | 2009-11-02 | 2013-04-17 | Salutaris Medical Devices Inc | METHOD AND DEVICES FOR THE ADMINISTRATION OF MINIMALLY INVASIVE EXTRACOLAR RADIATION |
| DE102009052552A1 (de) | 2009-11-10 | 2011-05-26 | Fluoron Gmbh | Spritze |
| USD645489S1 (en) | 2009-12-16 | 2011-09-20 | Glaukos Corporation | Gonioscopic system including an optical element attachment |
| USD645490S1 (en) | 2009-12-16 | 2011-09-20 | Glaukos Corporation | Gonioscopic system including an optical element attachment |
| US20120245505A1 (en) | 2009-12-16 | 2012-09-27 | Robinson Michael R | Intracameral devices for sustained delivery |
| US8177747B2 (en) | 2009-12-22 | 2012-05-15 | Alcon Research, Ltd. | Method and apparatus for drug delivery |
| US20110238036A1 (en) | 2009-12-23 | 2011-09-29 | Psivida Us, Inc. | Sustained release delivery devices |
| US8529492B2 (en) | 2009-12-23 | 2013-09-10 | Trascend Medical, Inc. | Drug delivery devices and methods |
| KR102337046B1 (ko) | 2010-01-22 | 2021-12-08 | 알러간, 인코포레이티드 | 전방내 서방성 치료제 이식물 |
| US10166142B2 (en) | 2010-01-29 | 2019-01-01 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
| WO2011097634A1 (en) | 2010-02-08 | 2011-08-11 | On Demand Therapeutics, Inc. | Low-permeability, laser-activated drug delivery device |
| US8889193B2 (en) | 2010-02-25 | 2014-11-18 | The Johns Hopkins University | Sustained delivery of therapeutic agents to an eye compartment |
| US20130071349A1 (en) | 2010-03-02 | 2013-03-21 | Allergan, Inc. | Biodegradable polymers for lowering intraocular pressure |
| GB201003731D0 (en) | 2010-03-05 | 2010-04-21 | Univ Strathclyde | Immediate/delayed drug delivery |
| US9408746B2 (en) | 2010-03-31 | 2016-08-09 | Ocuject, Llc | Device and method for intraocular drug delivery |
| US9320647B2 (en) | 2010-03-31 | 2016-04-26 | Ocuject, Llc | Device and method for intraocular drug delivery |
| JP2013524275A (ja) | 2010-04-03 | 2013-06-17 | ドシ,プラフル | 薬剤を含む医療機器、その製造方法とその使用方法 |
| EP2555749B1 (en) | 2010-04-06 | 2016-10-26 | Allergan, Inc. | Sustained-release reservoir implants for intracameral drug delivery |
| US20110251568A1 (en) | 2010-04-08 | 2011-10-13 | Beeley Nathan R F | Punctal plugs for controlled release of therapeutic agents |
| JP2013526572A (ja) | 2010-05-17 | 2013-06-24 | アエリエ・ファーマシューティカルズ・インコーポレーテッド | 眼治療薬の送達のための薬物送達装置 |
| US8444589B2 (en) | 2010-06-09 | 2013-05-21 | Transcend Medical, Inc. | Ocular implant with fluid outflow pathways having microporous membranes |
| KR101180032B1 (ko) | 2010-07-12 | 2012-09-05 | 인싸이토(주) | 외형 조절이 가능한 중공형 마이크로니들의 제조방법 |
| US20120022505A1 (en) | 2010-07-20 | 2012-01-26 | Bruno Dacquay | Closed loop glaucoma drug delivery system |
| WO2012019136A2 (en) | 2010-08-05 | 2012-02-09 | Forsight Vision 4, Inc. | Injector apparatus and method for drug delivery |
| PT2600812T (pt) * | 2010-08-05 | 2021-11-09 | Forsight Vision4 Inc | Aparelho para tratar um olho |
| US8235053B2 (en) | 2010-09-08 | 2012-08-07 | Alcon Research, Ltd. | Implantable punctal plug |
| US8864703B2 (en) | 2010-10-05 | 2014-10-21 | Alcon Research, Ltd. | Drug introduction and placement system |
| US9022967B2 (en) | 2010-10-08 | 2015-05-05 | Sinopsys Surgical, Inc. | Implant device, tool, and methods relating to treatment of paranasal sinuses |
| US8915877B2 (en) | 2010-10-12 | 2014-12-23 | Emmett T. Cunningham, JR. | Glaucoma drainage device and uses thereof |
| US9370444B2 (en) | 2010-10-12 | 2016-06-21 | Emmett T. Cunningham, JR. | Subconjunctival conformer device and uses thereof |
| US20120100187A1 (en) | 2010-10-26 | 2012-04-26 | Surmodics, Inc. | Coatings and methods for controlled elution of hydrophilic active agents |
| US9668915B2 (en) | 2010-11-24 | 2017-06-06 | Dose Medical Corporation | Drug eluting ocular implant |
| CA2822039C (en) | 2010-12-16 | 2019-05-28 | Allergan, Inc. | Sulfur derivatives as chemokine receptor modulators |
| WO2012088306A2 (en) | 2010-12-22 | 2012-06-28 | Psivida Us, Inc. | Two-piece injectable drug delivery device with heat-cured seal |
| ES2686020T3 (es) | 2011-01-24 | 2018-10-16 | Emd Millipore Corporation | Prueba acelerada de integridad de gases mezclados de materiales porosos |
| JP2012198134A (ja) | 2011-03-22 | 2012-10-18 | Chugoku Electric Power Co Inc:The | 事故点標定装置、プログラム |
| US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
| US20130004651A1 (en) | 2011-07-01 | 2013-01-03 | Patty Fu-Giles | Sustained drug release from body implants using nanoparticle-embedded polymeric coating materials |
| US20130018360A1 (en) | 2011-07-13 | 2013-01-17 | Marissa Dockendorf | Method for delivering ophthalmic drugs |
| US8486031B2 (en) | 2011-07-29 | 2013-07-16 | Allan J. Bogdan | Eye treatment apparatus |
| US20130053794A1 (en) | 2011-08-29 | 2013-02-28 | Suzanne Cadden | Sustained release delivery of active agents to treat glaucoma and ocular hypertension |
| WO2013040238A2 (en) | 2011-09-13 | 2013-03-21 | Vista Scientific Llc | Sustained release ocular drug delivery devices and methods of manufacture |
| EP2755549A1 (en) | 2011-09-13 | 2014-07-23 | Dose Medical Corporation | Intraocular physiological sensor |
| CA2848397C (en) | 2011-09-14 | 2022-04-26 | Forsight Vision5, Inc. | Ocular insert apparatus and methods |
| US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
| US8771220B2 (en) | 2011-12-07 | 2014-07-08 | Alcon Research, Ltd. | Glaucoma active pressure regulation shunt |
| US8852136B2 (en) | 2011-12-08 | 2014-10-07 | Aquesys, Inc. | Methods for placing a shunt into the intra-scleral space |
| US8579848B2 (en) | 2011-12-09 | 2013-11-12 | Alcon Research, Ltd. | Active drainage systems with pressure-driven valves and electronically-driven pump |
| US8945214B2 (en) | 2011-12-19 | 2015-02-03 | Allergan, Inc. | Intravitreal applicator |
| US9241829B2 (en) | 2011-12-20 | 2016-01-26 | Abbott Medical Optics Inc. | Implantable intraocular drug delivery apparatus, system and method |
| EP2811952A1 (en) | 2012-02-07 | 2014-12-17 | On Demand Therapeutics, Inc. | Drug delivery devices and methods of use thereof |
| US9095412B2 (en) | 2012-03-20 | 2015-08-04 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| US9554940B2 (en) | 2012-03-26 | 2017-01-31 | Glaukos Corporation | System and method for delivering multiple ocular implants |
| US9504603B2 (en) | 2012-04-02 | 2016-11-29 | Ocuject, Llc | Intraocular delivery devices and methods therefor |
| ES3014183T3 (en) | 2012-04-19 | 2025-04-21 | Alcon Inc | Delivery system for ocular implant |
| US9241832B2 (en) | 2012-04-24 | 2016-01-26 | Transcend Medical, Inc. | Delivery system for ocular implant |
| EP2956096A1 (en) | 2013-02-15 | 2015-12-23 | Allergan, Inc. | Sustained drug delivery implant |
| US9730638B2 (en) | 2013-03-13 | 2017-08-15 | Glaukos Corporation | Intraocular physiological sensor |
| US9592151B2 (en) | 2013-03-15 | 2017-03-14 | Glaukos Corporation | Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye |
| US10517759B2 (en) | 2013-03-15 | 2019-12-31 | Glaukos Corporation | Glaucoma stent and methods thereof for glaucoma treatment |
| WO2014165308A2 (en) | 2013-04-01 | 2014-10-09 | Allergan, Inc. | Microsphere drug delivery system for sustained intraocular release |
| CA2830555A1 (en) | 2013-10-18 | 2015-04-18 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| EP4046628A1 (en) | 2013-10-31 | 2022-08-24 | Allergan, Inc. | Prostamide-containing intraocular implants and methods of use thereof |
| CN106029019B (zh) | 2014-02-26 | 2020-07-03 | 阿勒根公司 | 眼内植入体递送设备及其使用方法 |
| AU2015266850B2 (en) | 2014-05-29 | 2019-12-05 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| WO2016023116A1 (en) | 2014-08-12 | 2016-02-18 | Patrick Gooi | Device, delivery system, and method for ocular therapy |
| CN107405306A (zh) | 2014-09-19 | 2017-11-28 | 奥叙拉尔有限公司 | 眼部药物组合物 |
| CA2980289C (en) | 2015-03-20 | 2024-05-14 | Glaukos Corporation | Gonioscopic devices |
| WO2016187355A1 (en) | 2015-05-20 | 2016-11-24 | Glaukos Corporation | Therapeutic drug compositions and implants for delivery of same |
| JP6916742B2 (ja) | 2015-06-03 | 2021-08-11 | アクエシス, インコーポレイテッド | Ab externo(眼外から眼内へ)の眼内シャント配置 |
| WO2017015633A1 (en) | 2015-07-22 | 2017-01-26 | Glaukos Corporation | Ocular implants for reduction of intraocular pressure |
| WO2017040853A1 (en) | 2015-09-02 | 2017-03-09 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
| US20180333296A1 (en) | 2015-09-02 | 2018-11-22 | Dose Medical Corporation | Drug delivery implants as intraocular drug depots and methods of using same |
| GB2543645B (en) | 2015-09-17 | 2019-01-02 | Oxular Ltd | Ophthalmic Injection device |
| US11564833B2 (en) | 2015-09-25 | 2023-01-31 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
| KR20170058811A (ko) | 2015-11-19 | 2017-05-29 | 글라우코스 코포레이션 | 전달 장치 시스템 및 녹내장 치료용 임플란트 |
| CA3022830A1 (en) | 2016-04-20 | 2017-10-26 | Harold Alexander Heitzmann | Bioresorbable ocular drug delivery device |
| US10674906B2 (en) | 2017-02-24 | 2020-06-09 | Glaukos Corporation | Gonioscopes |
| USD833008S1 (en) | 2017-02-27 | 2018-11-06 | Glaukos Corporation | Gonioscope |
| US11116625B2 (en) | 2017-09-28 | 2021-09-14 | Glaukos Corporation | Apparatus and method for controlling placement of intraocular implants |
| WO2019068026A1 (en) | 2017-09-29 | 2019-04-04 | Glaukos Corporation | INTRAOCULAR PHYSIOLOGICAL SENSOR |
| CN113893085B (zh) | 2017-10-06 | 2024-05-24 | 格劳科斯公司 | 用于递送多个眼部植入物的系统和方法 |
| USD846738S1 (en) | 2017-10-27 | 2019-04-23 | Glaukos Corporation | Implant delivery apparatus |
| EP3773375B1 (en) | 2018-04-12 | 2023-04-12 | New World Medical, Inc. | Device for intraocular fluid injection |
| JP2021532853A (ja) | 2018-07-23 | 2021-12-02 | ザ リージェンツ オブ ザ ユニヴァーシティ オブ コロラド,ア ボディ コーポレイト | 薬物送達のための眼科用装置 |
| WO2020172615A1 (en) | 2019-02-22 | 2020-08-27 | Glaukos Corporation | Compounds for the treatment of ocular disease |
| WO2021173662A1 (en) | 2020-02-24 | 2021-09-02 | SpyGlass Ophthalmics, Inc. | Intraocular drug delivery platform |
| US11399977B2 (en) | 2020-06-04 | 2022-08-02 | SpyGlass Pharma, Inc. | Ophthalmic implant system for drug delivery |
| US20220104936A1 (en) | 2020-10-05 | 2022-04-07 | SpyGlass Pharma, Inc. | IOL with Drug Delivery Devices and Uninterrupted PCO Barrier Edge |
| EP4236868B1 (en) | 2020-10-28 | 2026-07-22 | Spyglass Pharma, Inc. | Sulcus implant with deformable haptics |
| CA3227200A1 (en) | 2021-07-28 | 2023-02-02 | SpyGlass Pharma, Inc. | Stabilized intraocular drug delivery systems and methods of use |
| JP2024528129A (ja) | 2021-07-30 | 2024-07-26 | スパイグラス ファーマ インコーポレイテッド | 眼内レンズアセンブリにデバイスを取り付けるためのシステム及び関連する方法 |
| AU2023273823A1 (en) | 2022-05-18 | 2024-12-05 | Glaukos Corporation | Novel applications of zwitterions in ophthalmic topical cream compositions and preparations |
| US20240024093A1 (en) | 2022-07-22 | 2024-01-25 | SpyGlass Pharma, Inc. | Intraocular drug delivery systems and methods of use |
| WO2025170932A1 (en) | 2024-02-05 | 2025-08-14 | Glaukos Corporation | Systems, devices and methods for delivering an implant |
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2017
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- 2017-04-20 US US16/095,680 patent/US11318043B2/en active Active
- 2017-04-20 CN CN201780038262.9A patent/CN109937025B/zh active Active
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| AU2017252294B2 (en) | 2021-12-02 |
| AU2022201392B2 (en) | 2024-02-29 |
| US12667486B2 (en) | 2026-06-30 |
| AU2022201392A1 (en) | 2022-03-24 |
| US20220313486A1 (en) | 2022-10-06 |
| JP2022024060A (ja) | 2022-02-08 |
| CN109937025A (zh) | 2019-06-25 |
| JP7003110B2 (ja) | 2022-01-20 |
| AU2017252294A1 (en) | 2018-12-06 |
| WO2017184881A1 (en) | 2017-10-26 |
| CN109937025B (zh) | 2022-07-29 |
| US20190125581A1 (en) | 2019-05-02 |
| JP2024161525A (ja) | 2024-11-19 |
| US11318043B2 (en) | 2022-05-03 |
| CN115120405B (zh) | 2026-03-10 |
| EP3442479A1 (en) | 2019-02-20 |
| EP3442479B1 (en) | 2026-03-04 |
| JP2019514640A (ja) | 2019-06-06 |
| US20250161110A1 (en) | 2025-05-22 |
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