CA2888993A1 - Assessment and improvement of treatment using imaging of physiological responses to radiation therapy - Google Patents
Assessment and improvement of treatment using imaging of physiological responses to radiation therapy Download PDFInfo
- Publication number
- CA2888993A1 CA2888993A1 CA2888993A CA2888993A CA2888993A1 CA 2888993 A1 CA2888993 A1 CA 2888993A1 CA 2888993 A CA2888993 A CA 2888993A CA 2888993 A CA2888993 A CA 2888993A CA 2888993 A1 CA2888993 A1 CA 2888993A1
- Authority
- CA
- Canada
- Prior art keywords
- edema
- radiation
- delivered
- treatment
- analysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000011282 treatment Methods 0.000 title claims abstract description 111
- 238000001959 radiotherapy Methods 0.000 title claims abstract description 59
- 238000003384 imaging method Methods 0.000 title description 15
- 230000006872 improvement Effects 0.000 title description 4
- 230000006461 physiological response Effects 0.000 title description 2
- 230000005855 radiation Effects 0.000 claims abstract description 159
- 206010030113 Oedema Diseases 0.000 claims abstract description 150
- 238000000034 method Methods 0.000 claims abstract description 54
- 230000009471 action Effects 0.000 claims abstract description 16
- 238000002595 magnetic resonance imaging Methods 0.000 claims description 94
- 238000004458 analytical method Methods 0.000 claims description 57
- 230000008859 change Effects 0.000 claims description 34
- 230000001965 increasing effect Effects 0.000 claims description 30
- 238000012384 transportation and delivery Methods 0.000 claims description 27
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 23
- 239000001257 hydrogen Substances 0.000 claims description 23
- 229910052739 hydrogen Inorganic materials 0.000 claims description 23
- 230000005865 ionizing radiation Effects 0.000 claims description 23
- 230000004044 response Effects 0.000 claims description 22
- 238000013459 approach Methods 0.000 claims description 16
- 230000033001 locomotion Effects 0.000 claims description 14
- 238000004590 computer program Methods 0.000 claims description 10
- 238000004364 calculation method Methods 0.000 claims description 6
- 230000002596 correlated effect Effects 0.000 claims description 6
- 238000004891 communication Methods 0.000 claims description 3
- 238000010884 ion-beam technique Methods 0.000 claims description 2
- 239000012530 fluid Substances 0.000 abstract description 31
- 238000005259 measurement Methods 0.000 abstract description 5
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 210000001519 tissue Anatomy 0.000 description 127
- 210000004027 cell Anatomy 0.000 description 71
- 206010028980 Neoplasm Diseases 0.000 description 61
- 230000000694 effects Effects 0.000 description 38
- 230000006378 damage Effects 0.000 description 37
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 36
- 230000004054 inflammatory process Effects 0.000 description 35
- 206010061218 Inflammation Diseases 0.000 description 34
- 201000011510 cancer Diseases 0.000 description 28
- 230000005291 magnetic effect Effects 0.000 description 17
- 230000008961 swelling Effects 0.000 description 17
- 230000006870 function Effects 0.000 description 14
- 210000000056 organ Anatomy 0.000 description 13
- 210000004204 blood vessel Anatomy 0.000 description 12
- 201000010099 disease Diseases 0.000 description 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 12
- 230000003993 interaction Effects 0.000 description 12
- 230000008569 process Effects 0.000 description 12
- 208000038016 acute inflammation Diseases 0.000 description 11
- 230000006022 acute inflammation Effects 0.000 description 11
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 11
- 238000009826 distribution Methods 0.000 description 11
- 210000000130 stem cell Anatomy 0.000 description 11
- 230000001154 acute effect Effects 0.000 description 10
- 210000004369 blood Anatomy 0.000 description 10
- 239000008280 blood Substances 0.000 description 10
- 230000007246 mechanism Effects 0.000 description 10
- 230000035699 permeability Effects 0.000 description 10
- 102000004169 proteins and genes Human genes 0.000 description 10
- 108090000623 proteins and genes Proteins 0.000 description 10
- 108020004414 DNA Proteins 0.000 description 9
- 230000030833 cell death Effects 0.000 description 9
- 238000009792 diffusion process Methods 0.000 description 9
- 230000005415 magnetization Effects 0.000 description 9
- 230000036407 pain Effects 0.000 description 9
- 210000003491 skin Anatomy 0.000 description 9
- 238000001356 surgical procedure Methods 0.000 description 9
- 210000004556 brain Anatomy 0.000 description 8
- 230000005779 cell damage Effects 0.000 description 8
- 230000001537 neural effect Effects 0.000 description 8
- 238000012546 transfer Methods 0.000 description 8
- 238000010586 diagram Methods 0.000 description 7
- 230000002757 inflammatory effect Effects 0.000 description 7
- 230000007775 late Effects 0.000 description 7
- 239000012071 phase Substances 0.000 description 7
- 238000013439 planning Methods 0.000 description 7
- 210000002381 plasma Anatomy 0.000 description 7
- 230000008439 repair process Effects 0.000 description 7
- 206010025282 Lymphoedema Diseases 0.000 description 6
- 238000009825 accumulation Methods 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 6
- 208000037976 chronic inflammation Diseases 0.000 description 6
- 230000006020 chronic inflammation Effects 0.000 description 6
- 230000001186 cumulative effect Effects 0.000 description 6
- 230000002706 hydrostatic effect Effects 0.000 description 6
- 208000014674 injury Diseases 0.000 description 6
- 208000002502 lymphedema Diseases 0.000 description 6
- 239000001301 oxygen Substances 0.000 description 6
- 229910052760 oxygen Inorganic materials 0.000 description 6
- 210000004881 tumor cell Anatomy 0.000 description 6
- 208000027418 Wounds and injury Diseases 0.000 description 5
- 230000002159 abnormal effect Effects 0.000 description 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 5
- 230000001413 cellular effect Effects 0.000 description 5
- 238000005194 fractionation Methods 0.000 description 5
- 208000014829 head and neck neoplasm Diseases 0.000 description 5
- 230000028709 inflammatory response Effects 0.000 description 5
- 230000000266 injurious effect Effects 0.000 description 5
- 230000003902 lesion Effects 0.000 description 5
- 210000000265 leukocyte Anatomy 0.000 description 5
- 201000006417 multiple sclerosis Diseases 0.000 description 5
- 230000002829 reductive effect Effects 0.000 description 5
- 230000003068 static effect Effects 0.000 description 5
- 102000004506 Blood Proteins Human genes 0.000 description 4
- 108010017384 Blood Proteins Proteins 0.000 description 4
- 230000005778 DNA damage Effects 0.000 description 4
- 231100000277 DNA damage Toxicity 0.000 description 4
- 206010016654 Fibrosis Diseases 0.000 description 4
- 206010021143 Hypoxia Diseases 0.000 description 4
- 206010028665 Myxoedema Diseases 0.000 description 4
- 239000002671 adjuvant Substances 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 210000000481 breast Anatomy 0.000 description 4
- 230000022131 cell cycle Effects 0.000 description 4
- 208000037887 cell injury Diseases 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 238000002512 chemotherapy Methods 0.000 description 4
- 230000007423 decrease Effects 0.000 description 4
- 238000002597 diffusion-weighted imaging Methods 0.000 description 4
- 210000003722 extracellular fluid Anatomy 0.000 description 4
- 210000001508 eye Anatomy 0.000 description 4
- 230000004761 fibrosis Effects 0.000 description 4
- 210000003128 head Anatomy 0.000 description 4
- 208000015181 infectious disease Diseases 0.000 description 4
- 238000002075 inversion recovery Methods 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 4
- 210000004185 liver Anatomy 0.000 description 4
- 230000007774 longterm Effects 0.000 description 4
- 210000001165 lymph node Anatomy 0.000 description 4
- 210000004324 lymphatic system Anatomy 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 208000003786 myxedema Diseases 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 238000001228 spectrum Methods 0.000 description 4
- 230000001052 transient effect Effects 0.000 description 4
- 230000002792 vascular Effects 0.000 description 4
- 230000024883 vasodilation Effects 0.000 description 4
- 201000004384 Alopecia Diseases 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 3
- 206010006187 Breast cancer Diseases 0.000 description 3
- 208000026310 Breast neoplasm Diseases 0.000 description 3
- 102000001554 Hemoglobins Human genes 0.000 description 3
- 108010054147 Hemoglobins Proteins 0.000 description 3
- 206010028813 Nausea Diseases 0.000 description 3
- 206010037423 Pulmonary oedema Diseases 0.000 description 3
- 241000287181 Sturnus vulgaris Species 0.000 description 3
- 210000000577 adipose tissue Anatomy 0.000 description 3
- 238000002583 angiography Methods 0.000 description 3
- 230000032823 cell division Effects 0.000 description 3
- 230000003727 cerebral blood flow Effects 0.000 description 3
- 230000006999 cognitive decline Effects 0.000 description 3
- 208000010877 cognitive disease Diseases 0.000 description 3
- 230000001419 dependent effect Effects 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 238000002599 functional magnetic resonance imaging Methods 0.000 description 3
- 230000002068 genetic effect Effects 0.000 description 3
- 210000002149 gonad Anatomy 0.000 description 3
- 208000024963 hair loss Diseases 0.000 description 3
- 230000003676 hair loss Effects 0.000 description 3
- 230000009931 harmful effect Effects 0.000 description 3
- 230000035876 healing Effects 0.000 description 3
- 230000036571 hydration Effects 0.000 description 3
- 238000006703 hydration reaction Methods 0.000 description 3
- 230000001146 hypoxic effect Effects 0.000 description 3
- 238000007917 intracranial administration Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 210000002751 lymph Anatomy 0.000 description 3
- 210000002540 macrophage Anatomy 0.000 description 3
- 230000005012 migration Effects 0.000 description 3
- 238000013508 migration Methods 0.000 description 3
- 230000004660 morphological change Effects 0.000 description 3
- 230000008693 nausea Effects 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 244000052769 pathogen Species 0.000 description 3
- 230000037361 pathway Effects 0.000 description 3
- 102000007863 pattern recognition receptors Human genes 0.000 description 3
- 108010089193 pattern recognition receptors Proteins 0.000 description 3
- 230000035935 pregnancy Effects 0.000 description 3
- 208000005333 pulmonary edema Diseases 0.000 description 3
- 108020003175 receptors Proteins 0.000 description 3
- 102000005962 receptors Human genes 0.000 description 3
- 230000037390 scarring Effects 0.000 description 3
- 208000011571 secondary malignant neoplasm Diseases 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 238000004611 spectroscopical analysis Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000002459 sustained effect Effects 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 230000008733 trauma Effects 0.000 description 3
- 208000003174 Brain Neoplasms Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 206010017912 Gastroenteritis radiation Diseases 0.000 description 2
- 206010019280 Heart failures Diseases 0.000 description 2
- 206010025323 Lymphomas Diseases 0.000 description 2
- 239000002616 MRI contrast agent Substances 0.000 description 2
- 206010029164 Nephrotic syndrome Diseases 0.000 description 2
- 208000002151 Pleural effusion Diseases 0.000 description 2
- 230000018199 S phase Effects 0.000 description 2
- 208000006011 Stroke Diseases 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 206010052428 Wound Diseases 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 210000003484 anatomy Anatomy 0.000 description 2
- 238000003491 array Methods 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 125000004429 atom Chemical group 0.000 description 2
- 230000002238 attenuated effect Effects 0.000 description 2
- 210000003050 axon Anatomy 0.000 description 2
- 231100000504 carcinogenesis Toxicity 0.000 description 2
- 230000002490 cerebral effect Effects 0.000 description 2
- 238000000701 chemical imaging Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 239000002872 contrast media Substances 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 230000002498 deadly effect Effects 0.000 description 2
- 210000004443 dendritic cell Anatomy 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000004980 dosimetry Methods 0.000 description 2
- 230000005782 double-strand break Effects 0.000 description 2
- 206010013781 dry mouth Diseases 0.000 description 2
- 230000002900 effect on cell Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 238000011010 flushing procedure Methods 0.000 description 2
- 208000019622 heart disease Diseases 0.000 description 2
- 210000003630 histaminocyte Anatomy 0.000 description 2
- 210000003701 histiocyte Anatomy 0.000 description 2
- 210000000987 immune system Anatomy 0.000 description 2
- 230000001771 impaired effect Effects 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
- 238000007373 indentation Methods 0.000 description 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 description 2
- 208000000509 infertility Diseases 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 231100000535 infertility Toxicity 0.000 description 2
- 230000008595 infiltration Effects 0.000 description 2
- 238000001764 infiltration Methods 0.000 description 2
- 210000001865 kupffer cell Anatomy 0.000 description 2
- 231100000518 lethal Toxicity 0.000 description 2
- 230000001665 lethal effect Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- 238000013182 magnetic resonance venography Methods 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 210000004379 membrane Anatomy 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 239000002207 metabolite Substances 0.000 description 2
- 210000004877 mucosa Anatomy 0.000 description 2
- 210000001640 nerve ending Anatomy 0.000 description 2
- 210000002569 neuron Anatomy 0.000 description 2
- 210000000440 neutrophil Anatomy 0.000 description 2
- 238000011275 oncology therapy Methods 0.000 description 2
- 210000004738 parenchymal cell Anatomy 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 230000007170 pathology Effects 0.000 description 2
- 230000035755 proliferation Effects 0.000 description 2
- 230000000541 pulsatile effect Effects 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 238000011002 quantification Methods 0.000 description 2
- 208000020624 radiation proctitis Diseases 0.000 description 2
- 238000003608 radiolysis reaction Methods 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000011514 reflex Effects 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 231100000241 scar Toxicity 0.000 description 2
- 230000000392 somatic effect Effects 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- 239000003270 steroid hormone Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 230000008685 targeting Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 210000003932 urinary bladder Anatomy 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- 210000005166 vasculature Anatomy 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 210000004885 white matter Anatomy 0.000 description 2
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 description 1
- 206010061424 Anal cancer Diseases 0.000 description 1
- 206010002329 Aneurysm Diseases 0.000 description 1
- 208000007860 Anus Neoplasms Diseases 0.000 description 1
- 206010003399 Arthropod bite Diseases 0.000 description 1
- 206010003402 Arthropod sting Diseases 0.000 description 1
- 206010003445 Ascites Diseases 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 238000012935 Averaging Methods 0.000 description 1
- 102400000967 Bradykinin Human genes 0.000 description 1
- 101800004538 Bradykinin Proteins 0.000 description 1
- 206010048962 Brain oedema Diseases 0.000 description 1
- 230000005653 Brownian motion process Effects 0.000 description 1
- 208000005623 Carcinogenesis Diseases 0.000 description 1
- 201000009030 Carcinoma Diseases 0.000 description 1
- 102000019034 Chemokines Human genes 0.000 description 1
- 108010012236 Chemokines Proteins 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 206010067276 Cytotoxic oedema Diseases 0.000 description 1
- 230000009946 DNA mutation Effects 0.000 description 1
- 208000016192 Demyelinating disease Diseases 0.000 description 1
- 206010012305 Demyelination Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010012442 Dermatitis contact Diseases 0.000 description 1
- 208000018672 Dilatation Diseases 0.000 description 1
- 208000003556 Dry Eye Syndromes Diseases 0.000 description 1
- 206010013774 Dry eye Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010015866 Extravasation Diseases 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 201000006353 Filariasis Diseases 0.000 description 1
- 230000010337 G2 phase Effects 0.000 description 1
- 229910052688 Gadolinium Inorganic materials 0.000 description 1
- 206010018092 Generalised oedema Diseases 0.000 description 1
- 208000010412 Glaucoma Diseases 0.000 description 1
- QXZGBUJJYSLZLT-UHFFFAOYSA-N H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH Natural products NC(N)=NCCCC(N)C(=O)N1CCCC1C(=O)N1C(C(=O)NCC(=O)NC(CC=2C=CC=CC=2)C(=O)NC(CO)C(=O)N2C(CCC2)C(=O)NC(CC=2C=CC=CC=2)C(=O)NC(CCCN=C(N)N)C(O)=O)CCC1 QXZGBUJJYSLZLT-UHFFFAOYSA-N 0.000 description 1
- 206010066476 Haematological malignancy Diseases 0.000 description 1
- 208000004454 Hyperalgesia Diseases 0.000 description 1
- 208000035154 Hyperesthesia Diseases 0.000 description 1
- 206010020843 Hyperthermia Diseases 0.000 description 1
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 108060003951 Immunoglobulin Proteins 0.000 description 1
- 206010061216 Infarction Diseases 0.000 description 1
- 208000006877 Insect Bites and Stings Diseases 0.000 description 1
- 208000032382 Ischaemic stroke Diseases 0.000 description 1
- 206010024558 Lip oedema Diseases 0.000 description 1
- 208000007021 Lipedema Diseases 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 230000027311 M phase Effects 0.000 description 1
- 238000012307 MRI technique Methods 0.000 description 1
- 206010027476 Metastases Diseases 0.000 description 1
- 206010027452 Metastases to bone Diseases 0.000 description 1
- 206010059282 Metastases to central nervous system Diseases 0.000 description 1
- 102000006386 Myelin Proteins Human genes 0.000 description 1
- 108010083674 Myelin Proteins Proteins 0.000 description 1
- 206010028851 Necrosis Diseases 0.000 description 1
- 208000034176 Neoplasms, Germ Cell and Embryonal Diseases 0.000 description 1
- 208000012902 Nervous system disease Diseases 0.000 description 1
- 208000025966 Neurological disease Diseases 0.000 description 1
- 206010030124 Oedema peripheral Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 206010033645 Pancreatitis Diseases 0.000 description 1
- 206010033892 Paraplegia Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 206010034545 Periorbital oedema Diseases 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 102400001018 Proadrenomedullin N-20 terminal peptide Human genes 0.000 description 1
- 101800000795 Proadrenomedullin N-20 terminal peptide Proteins 0.000 description 1
- 208000015634 Rectal Neoplasms Diseases 0.000 description 1
- 208000006265 Renal cell carcinoma Diseases 0.000 description 1
- 102000003800 Selectins Human genes 0.000 description 1
- 108090000184 Selectins Proteins 0.000 description 1
- 206010040844 Skin exfoliation Diseases 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 206010040914 Skin reaction Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 208000003589 Spider Bites Diseases 0.000 description 1
- 208000033809 Suppuration Diseases 0.000 description 1
- 208000000491 Tendinopathy Diseases 0.000 description 1
- 206010043255 Tendonitis Diseases 0.000 description 1
- 241000858129 Toxicodendron diversilobum Species 0.000 description 1
- 102000040945 Transcription factor Human genes 0.000 description 1
- 108091023040 Transcription factor Proteins 0.000 description 1
- 206010064390 Tumour invasion Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 208000024780 Urticaria Diseases 0.000 description 1
- 206010046996 Varicose vein Diseases 0.000 description 1
- 241000244005 Wuchereria bancrofti Species 0.000 description 1
- 208000005946 Xerostomia Diseases 0.000 description 1
- 238000010317 ablation therapy Methods 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000010398 acute inflammatory response Effects 0.000 description 1
- 210000005006 adaptive immune system Anatomy 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 208000008445 altitude sickness Diseases 0.000 description 1
- 208000024783 anasarca Diseases 0.000 description 1
- 230000003474 anti-emetic effect Effects 0.000 description 1
- 229940125683 antiemetic agent Drugs 0.000 description 1
- 239000002111 antiemetic agent Substances 0.000 description 1
- 201000011165 anus cancer Diseases 0.000 description 1
- 210000000702 aorta abdominal Anatomy 0.000 description 1
- 210000002376 aorta thoracic Anatomy 0.000 description 1
- 210000002565 arteriole Anatomy 0.000 description 1
- 230000002917 arthritic effect Effects 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 230000017047 asymmetric cell division Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 210000002469 basement membrane Anatomy 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000008512 biological response Effects 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 238000002725 brachytherapy Methods 0.000 description 1
- QXZGBUJJYSLZLT-FDISYFBBSA-N bradykinin Chemical compound NC(=N)NCCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1[C@H](C(=O)NCC(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CO)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)CCC1 QXZGBUJJYSLZLT-FDISYFBBSA-N 0.000 description 1
- 208000006752 brain edema Diseases 0.000 description 1
- 210000000621 bronchi Anatomy 0.000 description 1
- 238000005537 brownian motion Methods 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 230000035571 calor Effects 0.000 description 1
- 230000036952 cancer formation Effects 0.000 description 1
- 230000009400 cancer invasion Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000023715 cellular developmental process Effects 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 230000003788 cerebral perfusion Effects 0.000 description 1
- 201000006612 cervical squamous cell carcinoma Diseases 0.000 description 1
- 229960005395 cetuximab Drugs 0.000 description 1
- 238000012824 chemical production Methods 0.000 description 1
- 231100000481 chemical toxicant Toxicity 0.000 description 1
- 230000003399 chemotactic effect Effects 0.000 description 1
- 239000012829 chemotherapy agent Substances 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 description 1
- 229960004316 cisplatin Drugs 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000004154 complement system Effects 0.000 description 1
- 238000002591 computed tomography Methods 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 210000001608 connective tissue cell Anatomy 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 208000010247 contact dermatitis Diseases 0.000 description 1
- 210000004087 cornea Anatomy 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000002681 cryosurgery Methods 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 238000002716 delivery method Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000035618 desquamation Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 238000002598 diffusion tensor imaging Methods 0.000 description 1
- 230000010339 dilation Effects 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 230000035620 dolor Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 210000003027 ear inner Anatomy 0.000 description 1
- 208000006036 elephantiasis Diseases 0.000 description 1
- 210000003038 endothelium Anatomy 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000002514 epidermal stem cell Anatomy 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 229940011871 estrogen Drugs 0.000 description 1
- 239000000262 estrogen Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 210000001723 extracellular space Anatomy 0.000 description 1
- 230000036251 extravasation Effects 0.000 description 1
- 210000005002 female reproductive tract Anatomy 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 230000020764 fibrinolysis Effects 0.000 description 1
- 230000003176 fibrotic effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000011404 fractionated radiotherapy Methods 0.000 description 1
- 230000009760 functional impairment Effects 0.000 description 1
- UIWYJDYFSGRHKR-UHFFFAOYSA-N gadolinium atom Chemical compound [Gd] UIWYJDYFSGRHKR-UHFFFAOYSA-N 0.000 description 1
- 201000010175 gallbladder cancer Diseases 0.000 description 1
- 201000007487 gallbladder carcinoma Diseases 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 231100000722 genetic damage Toxicity 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 210000003714 granulocyte Anatomy 0.000 description 1
- 210000004884 grey matter Anatomy 0.000 description 1
- 210000004013 groin Anatomy 0.000 description 1
- 125000005843 halogen group Chemical group 0.000 description 1
- 201000010536 head and neck cancer Diseases 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000003284 homeostatic effect Effects 0.000 description 1
- 230000013632 homeostatic process Effects 0.000 description 1
- KIUKXJAPPMFGSW-MNSSHETKSA-N hyaluronan Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H](C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-MNSSHETKSA-N 0.000 description 1
- 229940099552 hyaluronan Drugs 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 230000036031 hyperthermia Effects 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 229960001680 ibuprofen Drugs 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
- 229940072221 immunoglobulins Drugs 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 229960000905 indomethacin Drugs 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000007574 infarction Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 239000003999 initiator Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000015788 innate immune response Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 201000009941 intracranial hypertension Diseases 0.000 description 1
- 230000002601 intratumoral effect Effects 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 238000002665 ion therapy Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 230000000622 irritating effect Effects 0.000 description 1
- 230000000155 isotopic effect Effects 0.000 description 1
- 206010023332 keratitis Diseases 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 210000005240 left ventricle Anatomy 0.000 description 1
- 231100000225 lethality Toxicity 0.000 description 1
- 208000032839 leukemia Diseases 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 239000004973 liquid crystal related substance Substances 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 208000020816 lung neoplasm Diseases 0.000 description 1
- 206010025135 lupus erythematosus Diseases 0.000 description 1
- 230000001926 lymphatic effect Effects 0.000 description 1
- 210000001365 lymphatic vessel Anatomy 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 210000004962 mammalian cell Anatomy 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 201000001441 melanoma Diseases 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000003607 modifier Substances 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 208000018962 mouth sore Diseases 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000005012 myelin Anatomy 0.000 description 1
- 210000001087 myotubule Anatomy 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 238000011227 neoadjuvant chemotherapy Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 238000002610 neuroimaging Methods 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 238000009203 neutron therapy Methods 0.000 description 1
- MDJFHRLTPRPZLY-UHFFFAOYSA-N nimorazole Chemical compound [O-][N+](=O)C1=CN=CN1CCN1CCOCC1 MDJFHRLTPRPZLY-UHFFFAOYSA-N 0.000 description 1
- 229960004918 nimorazole Drugs 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 201000003077 normal pressure hydrocephalus Diseases 0.000 description 1
- 238000010606 normalization Methods 0.000 description 1
- 210000003924 normoblast Anatomy 0.000 description 1
- 238000001208 nuclear magnetic resonance pulse sequence Methods 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000000414 obstructive effect Effects 0.000 description 1
- 210000000287 oocyte Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- 238000002638 palliative care Methods 0.000 description 1
- PIRWNASAJNPKHT-SHZATDIYSA-N pamp Chemical compound C([C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)N)C(C)C)C1=CC=CC=C1 PIRWNASAJNPKHT-SHZATDIYSA-N 0.000 description 1
- 230000005298 paramagnetic effect Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 210000004224 pleura Anatomy 0.000 description 1
- 210000003281 pleural cavity Anatomy 0.000 description 1
- 230000002250 progressing effect Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000002599 prostaglandin synthase inhibitor Substances 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 108020001580 protein domains Proteins 0.000 description 1
- 239000012460 protein solution Substances 0.000 description 1
- 201000001474 proteinuria Diseases 0.000 description 1
- 238000002661 proton therapy Methods 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 210000003492 pulmonary vein Anatomy 0.000 description 1
- 201000007608 radiation cystitis Diseases 0.000 description 1
- 239000002534 radiation-sensitizing agent Substances 0.000 description 1
- 238000002601 radiography Methods 0.000 description 1
- 230000000637 radiosensitizating effect Effects 0.000 description 1
- 239000003642 reactive oxygen metabolite Substances 0.000 description 1
- 230000007115 recruitment Effects 0.000 description 1
- 206010038038 rectal cancer Diseases 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 201000001275 rectum cancer Diseases 0.000 description 1
- 210000002254 renal artery Anatomy 0.000 description 1
- 208000015347 renal cell adenocarcinoma Diseases 0.000 description 1
- 230000010410 reperfusion Effects 0.000 description 1
- 230000002629 repopulating effect Effects 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000002271 resection Methods 0.000 description 1
- 230000008458 response to injury Effects 0.000 description 1
- 230000026416 response to pain Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 230000036185 rubor Effects 0.000 description 1
- 210000003079 salivary gland Anatomy 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 210000001044 sensory neuron Anatomy 0.000 description 1
- 208000018196 severe conjunctivitis Diseases 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 230000019491 signal transduction Effects 0.000 description 1
- 230000003007 single stranded DNA break Effects 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 230000035483 skin reaction Effects 0.000 description 1
- 231100000430 skin reaction Toxicity 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000000264 spin echo pulse sequence Methods 0.000 description 1
- 230000024642 stem cell division Effects 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 108020003113 steroid hormone receptors Proteins 0.000 description 1
- 102000005969 steroid hormone receptors Human genes 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000011477 surgical intervention Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 210000000106 sweat gland Anatomy 0.000 description 1
- 201000004415 tendinitis Diseases 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 230000033912 thigmotaxis Effects 0.000 description 1
- 201000005060 thrombophlebitis Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 230000036269 ulceration Effects 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 210000000626 ureter Anatomy 0.000 description 1
- 208000027185 varicose disease Diseases 0.000 description 1
- 230000004865 vascular response Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 210000000264 venule Anatomy 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
- 208000005494 xerophthalmia Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1064—Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
- A61B5/0036—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room including treatment, e.g., using an implantable medical device, ablating, ventilating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4869—Determining body composition
- A61B5/4875—Hydration status, fluid retention of the body
- A61B5/4878—Evaluating oedema
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/50—NMR imaging systems based on the determination of relaxation times, e.g. T1 measurement by IR sequences; T2 measurement by multiple-echo sequences
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
- A61N2005/1055—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using magnetic resonance imaging [MRI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1071—Monitoring, verifying, controlling systems and methods for verifying the dose delivered by the treatment plan
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- High Energy & Nuclear Physics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261719337P | 2012-10-26 | 2012-10-26 | |
| US61/719,337 | 2012-10-26 | ||
| PCT/US2013/066963 WO2014066853A1 (en) | 2012-10-26 | 2013-10-25 | Assessment and improvement of treatment using imaging of physiological responses to radiation therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2888993A1 true CA2888993A1 (en) | 2014-05-01 |
Family
ID=49578561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2888993A Abandoned CA2888993A1 (en) | 2012-10-26 | 2013-10-25 | Assessment and improvement of treatment using imaging of physiological responses to radiation therapy |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US9889318B2 (enExample) |
| EP (2) | EP2911745B1 (enExample) |
| JP (2) | JP6382208B2 (enExample) |
| KR (1) | KR20150080527A (enExample) |
| CN (2) | CN104902956B (enExample) |
| AU (2) | AU2013334064A1 (enExample) |
| CA (1) | CA2888993A1 (enExample) |
| WO (1) | WO2014066853A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5110881B2 (ja) | 2004-02-20 | 2012-12-26 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイティド | 軟組織を同時に画像化しながら等角放射線治療を送達するためのシステム |
| AU2010262843B2 (en) * | 2009-06-19 | 2015-07-16 | Viewray Technologies, Inc. | System and method for performing tomographic image acquisition and reconstruction |
| CN102472830B (zh) | 2009-07-15 | 2016-03-30 | 微雷公司 | 用于使直线性加速器和磁共振成像设备彼此屏蔽的方法和装置 |
| US8803524B2 (en) | 2010-02-24 | 2014-08-12 | Viewray Incorporated | Split magnetic resonance imaging system |
| US8981779B2 (en) | 2011-12-13 | 2015-03-17 | Viewray Incorporated | Active resistive shimming fro MRI devices |
| US10561861B2 (en) | 2012-05-02 | 2020-02-18 | Viewray Technologies, Inc. | Videographic display of real-time medical treatment |
| US9889318B2 (en) | 2012-10-26 | 2018-02-13 | Viewray Technologies, Inc. | Assessment and improvement of treatment using imaging of physiological responses to radiation therapy |
| US9675271B2 (en) * | 2013-03-13 | 2017-06-13 | Viewray Technologies, Inc. | Systems and methods for radiotherapy with magnetic resonance imaging |
| US9446263B2 (en) | 2013-03-15 | 2016-09-20 | Viewray Technologies, Inc. | Systems and methods for linear accelerator radiotherapy with magnetic resonance imaging |
| JP6422637B2 (ja) * | 2013-08-20 | 2018-11-14 | 国立大学法人京都大学 | 磁気共鳴イメージング装置及び画像処理装置 |
| CN106659907A (zh) | 2014-06-20 | 2017-05-10 | 皇家飞利浦有限公司 | 热消融系统 |
| DE102014217283B4 (de) * | 2014-08-29 | 2016-03-31 | Siemens Aktiengesellschaft | Überwachung einer Strahlentherapie eines Patienten mittels einer MR-Fingerprinting-Methode |
| EP3209202B1 (en) * | 2014-10-20 | 2024-01-24 | New York University | Apparatus to select radiation dosage for tumor treatment based on cellular imaging |
| CN115337557B (zh) | 2015-02-11 | 2024-11-12 | 优瑞系统公司 | 用于辐射疗法的系统 |
| US10980478B2 (en) * | 2015-12-21 | 2021-04-20 | Koninklijke Philips N.V. | Device for tissue condition measurement |
| US10534054B2 (en) * | 2016-01-04 | 2020-01-14 | Canon Medical Systems Corporation | Magnetic resonance imaging apparatus and magnetic resonance imaging method |
| US20200002662A1 (en) * | 2016-02-18 | 2020-01-02 | University Health Network | Device, system and process for robotic radiobiology |
| US10172517B2 (en) * | 2016-02-25 | 2019-01-08 | Samsung Electronics Co., Ltd | Image-analysis for assessing heart failure |
| CN118750795A (zh) | 2016-03-02 | 2024-10-11 | 优瑞技术公司 | 放射疗法系统和相关的非暂时性计算机程序产品 |
| JP6278483B2 (ja) * | 2016-03-18 | 2018-02-14 | 国立大学法人広島大学 | 治療支援システム、治療支援システムの動作方法及び治療支援プログラム |
| KR101817423B1 (ko) * | 2016-04-29 | 2018-01-10 | 주식회사 한빔테크놀로지 | 호흡 연동 시스템 |
| KR101740464B1 (ko) * | 2016-10-20 | 2017-06-08 | (주)제이엘케이인스펙션 | 뇌졸중 진단 및 예후 예측 방법 및 시스템 |
| EP3554635B1 (en) | 2016-12-13 | 2021-01-20 | ViewRay Technologies, Inc. | Radiation therapy systems |
| WO2019099902A1 (en) | 2017-11-17 | 2019-05-23 | The Research Foundation for State University of New York | A method for treating damaged peripheral nerves using x-ray microbeam irradiation |
| JP7127126B2 (ja) | 2017-12-06 | 2022-08-29 | ビューレイ・テクノロジーズ・インコーポレイテッド | 放射線治療のシステム、方法およびソフトウェア |
| US11209509B2 (en) | 2018-05-16 | 2021-12-28 | Viewray Technologies, Inc. | Resistive electromagnet systems and methods |
| CN109009037B (zh) * | 2018-06-20 | 2021-11-19 | 博动医学影像科技(上海)有限公司 | 基于个体性别获取血管压力差的计算方法及装置 |
| WO2020075749A1 (ja) | 2018-10-11 | 2020-04-16 | 富士フイルム株式会社 | 固体電解質組成物、全固体二次電池用シート、全固体二次電池用電極シート及び全固体二次電池 |
| CN109394200B (zh) * | 2018-12-16 | 2021-10-19 | 冯兴怀 | 用于液体治疗、容量管理的微循环脉冲血流监测系统和方法 |
| US11786755B2 (en) | 2019-02-07 | 2023-10-17 | Canon Medical Systems Corporation | Radiotherapy support apparatus, radiotherapy system, and radiotherapy support method |
| KR102277779B1 (ko) * | 2019-08-22 | 2021-07-15 | (주)에스원바이오 | 림프부종 진단을 위한 정보제공 방법 |
| US12207939B2 (en) | 2019-11-27 | 2025-01-28 | University Of Cincinnati | Assessing treatment response with estimated number of tumor cells |
| KR102384083B1 (ko) | 2020-10-07 | 2022-04-07 | 단국대학교 산학협력단 | 자기공명영상을 이용한 천장관절염 진단 및 염증 정도를 평가하기 위한 장치 및 방법 |
| CN113262390B (zh) * | 2021-06-28 | 2022-06-21 | 真实维度科技控股(珠海)有限公司 | 一种基于放射性粒子植入的肿瘤放疗效果评价方法 |
| JP2025024854A (ja) * | 2023-08-08 | 2025-02-21 | 株式会社日立製作所 | 治療支援システム及び治療支援方法 |
| WO2025080849A1 (en) * | 2023-10-10 | 2025-04-17 | The Methodist Hospital | Non-contrast computer tomography with ai-denoiser and dynamic range correction for net water uptake assessment |
| KR20250125489A (ko) * | 2024-02-14 | 2025-08-22 | 재단법인 아산사회복지재단 | 림프 수축의 정규성 판별을 통한 림프부종 발생 조기 평가장치 및 방법 |
Family Cites Families (438)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1014630A (en) | 1964-11-06 | 1965-12-31 | Mullard Ltd | Improvements in and relating to adjustable couches |
| US3569823A (en) | 1968-10-18 | 1971-03-09 | Perkin Elmer Corp | Nuclear magnetic resonance apparatus |
| US3735306A (en) | 1970-10-22 | 1973-05-22 | Varian Associates | Magnetic field shim coil structure utilizing laminated printed circuit sheets |
| US4233662A (en) | 1973-04-25 | 1980-11-11 | Emi Limited | Radiography |
| DE2455447C3 (de) | 1974-11-22 | 1981-02-05 | Siemens Ag, 1000 Berlin Und 8000 Muenchen | Patientenlagerungsvorrichtung eines Röntgengerätes |
| DE3121728A1 (de) | 1981-06-01 | 1982-12-16 | Siemens AG, 1000 Berlin und 8000 München | Patienten-lagerungsvorrichtung mit einer drehbaren lagerstatt |
| US4581580A (en) | 1983-12-14 | 1986-04-08 | General Electric Company | Intentionally non-orthogonal correction coils for high-homogeneity magnets |
| US4642569A (en) | 1983-12-16 | 1987-02-10 | General Electric Company | Shield for decoupling RF and gradient coils in an NMR apparatus |
| SE462013B (sv) | 1984-01-26 | 1990-04-30 | Kjell Olov Torgny Lindstroem | Behandlingsbord foer radioterapi av patienter |
| JPS60189905A (ja) | 1984-03-09 | 1985-09-27 | Mitsubishi Electric Corp | 高均一磁界発生装置 |
| JPS6224020U (enExample) | 1985-07-26 | 1987-02-13 | ||
| US4694837A (en) | 1985-08-09 | 1987-09-22 | Picker International, Inc. | Cardiac and respiratory gated magnetic resonance imaging |
| US4740753A (en) | 1986-01-03 | 1988-04-26 | General Electric Company | Magnet shimming using information derived from chemical shift imaging |
| US4771785A (en) | 1986-07-25 | 1988-09-20 | Resonex, Inc. | Magnetic resonance imaging apparatus and three-axis patient positioning assembly for use therewith |
| JPS63294839A (ja) | 1987-05-27 | 1988-12-01 | Nec Corp | 放射線治療用ctシミュレ−タ |
| DE3828639C2 (de) | 1987-08-24 | 1994-08-18 | Mitsubishi Electric Corp | Strahlentherapiegerät |
| US5027818A (en) | 1987-12-03 | 1991-07-02 | University Of Florida | Dosimetric technique for stereotactic radiosurgery same |
| EP0371303B1 (de) | 1988-11-29 | 1994-04-27 | Varian International AG. | Strahlentherapiegerät |
| US4851778A (en) | 1988-12-15 | 1989-07-25 | The Regents Of The University Of California | Enhanced S/N MRI for short TR nutation sequences |
| US5117829A (en) | 1989-03-31 | 1992-06-02 | Loma Linda University Medical Center | Patient alignment system and procedure for radiation treatment |
| US5006804A (en) | 1989-12-04 | 1991-04-09 | General Electric Company | Method of optimizing shim coil current selection in magnetic resonance magnets |
| US5094837A (en) * | 1990-01-22 | 1992-03-10 | Wayne State University | Method for use of magnetic resonance imaging to image pancreas using secretin |
| ES2131067T5 (es) | 1991-01-19 | 2004-10-16 | Meito Sangyo Kabushiki Kaisha | Composicion que contiene particulas ultrafinas de oxido metalico magnetico. |
| US6405072B1 (en) | 1991-01-28 | 2002-06-11 | Sherwood Services Ag | Apparatus and method for determining a location of an anatomical target with reference to a medical apparatus |
| JP2735747B2 (ja) | 1991-09-03 | 1998-04-02 | ゼネラル・エレクトリック・カンパニイ | 追跡及びイメージング・システム |
| US5734384A (en) | 1991-11-29 | 1998-03-31 | Picker International, Inc. | Cross-referenced sectioning and reprojection of diagnostic image volumes |
| EP0591542B1 (en) | 1992-03-18 | 2003-01-02 | Sumitomo Special Metals Company Limited | Magnetic field generator for mri |
| US5317616A (en) | 1992-03-19 | 1994-05-31 | Wisconsin Alumni Research Foundation | Method and apparatus for radiation therapy |
| US5394452A (en) | 1992-03-19 | 1995-02-28 | Wisconsin Alumni Research Foundation | Verification system for radiation therapy |
| US5216255A (en) | 1992-03-31 | 1993-06-01 | Siemens Medical Laboratories | Beam profile generator for photon radiation |
| US5332908A (en) | 1992-03-31 | 1994-07-26 | Siemens Medical Laboratories, Inc. | Method for dynamic beam profile generation |
| US5382904A (en) | 1992-04-15 | 1995-01-17 | Houston Advanced Research Center | Structured coil electromagnets for magnetic resonance imaging and method for fabricating the same |
| DE4217496C2 (de) | 1992-05-27 | 1994-06-16 | Bruker Analytische Messtechnik | Shim-Verfahren |
| US5280428A (en) | 1992-07-14 | 1994-01-18 | General Electric Company | Method and apparatus for projecting diagnostic images from volumed diagnostic data accessed in data tubes |
| US5331552A (en) | 1992-07-14 | 1994-07-19 | General Electric Company | Method and apparatus for projecting diagnostic images from non-isotropic volumed diagnostic data |
| US5295488A (en) | 1992-08-05 | 1994-03-22 | General Electric Company | Method and apparatus for projecting diagnostic images from volumed diagnostic data |
| US5760582A (en) | 1992-07-23 | 1998-06-02 | Fonar Corporation | Optimized gradient coils and shim coils for magnetic resonance scanning systems |
| JPH0654916A (ja) | 1992-08-06 | 1994-03-01 | Mitsubishi Electric Corp | 呼吸モニタ治療方式 |
| US5596619A (en) | 1992-08-21 | 1997-01-21 | Nomos Corporation | Method and apparatus for conformal radiation therapy |
| US5391139A (en) | 1992-09-03 | 1995-02-21 | William Beaumont Hospital | Real time radiation treatment planning system |
| US5647361A (en) | 1992-09-28 | 1997-07-15 | Fonar Corporation | Magnetic resonance imaging method and apparatus for guiding invasive therapy |
| US6005916A (en) | 1992-10-14 | 1999-12-21 | Techniscan, Inc. | Apparatus and method for imaging with wavefields using inverse scattering techniques |
| IT1266276B1 (it) | 1993-02-26 | 1996-12-27 | C A T Di Corsini Giuseppe E C | Tavolo porta-paziente per l'effettuazione di esami medici. |
| US5361763A (en) | 1993-03-02 | 1994-11-08 | Wisconsin Alumni Research Foundation | Method for segmenting features in an image |
| JPH06315541A (ja) * | 1993-03-12 | 1994-11-15 | Toshiba Corp | 画像診断装置を用いた治療装置 |
| DE69431741T2 (de) | 1993-03-12 | 2003-09-11 | Kabushiki Kaisha Toshiba, Kawasaki | Vorrichtung zur medizinischen Behandlung mit Ultraschall |
| US5307812A (en) | 1993-03-26 | 1994-05-03 | General Electric Company | Heat surgery system monitored by real-time magnetic resonance profiling |
| EP0703805B1 (en) | 1993-06-09 | 1998-03-25 | Wisconsin Alumni Research Foundation | Radiation therapy system |
| US5373844A (en) | 1993-06-14 | 1994-12-20 | The Regents Of The University Of California | Inverse treatment planning method and apparatus for stereotactic radiosurgery |
| DE4333440C1 (de) | 1993-09-30 | 1995-04-06 | Siemens Ag | Verfahren zur Shimmung eines Magnetfeldes in einem Untersuchungsraum eines Kernspinresonanzgerätes |
| US5547454A (en) | 1993-11-02 | 1996-08-20 | Sandia Corporation | Ion-induced nuclear radiotherapy |
| US5365927A (en) | 1993-11-02 | 1994-11-22 | General Electric Company | Magnetic resonance imaging system with pointing device |
| US5378989A (en) | 1993-11-02 | 1995-01-03 | General Electric Company | Open gradient coils for magnetic resonance imaging |
| JPH07308302A (ja) * | 1993-11-26 | 1995-11-28 | Siemens Medical Syst Inc | 磁気共鳴を用いての、組織または流体の選択された領域の像の形成およびバックグランドの抑圧方法 |
| US5458125A (en) | 1994-01-28 | 1995-10-17 | Board Of Directors Of The Leland Standford Jr. University | Treatment planning method and apparatus for radiosurgery and radiation therapy |
| US5538494A (en) | 1994-03-17 | 1996-07-23 | Hitachi, Ltd. | Radioactive beam irradiation method and apparatus taking movement of the irradiation area into consideration |
| US5537452A (en) | 1994-05-10 | 1996-07-16 | Shepherd; Joseph S. | Radiation therapy and radiation surgery treatment system and methods of use of same |
| US5602982A (en) | 1994-09-23 | 1997-02-11 | Kelly Properties, Inc. | Universal automated training and testing software system |
| US5443068A (en) | 1994-09-26 | 1995-08-22 | General Electric Company | Mechanical positioner for magnetic resonance guided ultrasound therapy |
| US5513238A (en) | 1994-10-11 | 1996-04-30 | Radionics, Inc. | Automatic planning for radiation dosimetry |
| DE4437443C2 (de) | 1994-10-19 | 1996-09-12 | Siemens Ag | Verfahren zum Betrieb eines Kernspintomographiegerätes mit dynamisch lokalisierter Shimmung des Grundmagnetfeldes |
| US5511549A (en) | 1995-02-13 | 1996-04-30 | Loma Linda Medical Center | Normalizing and calibrating therapeutic radiation delivery systems |
| US5555283A (en) | 1995-06-07 | 1996-09-10 | Board Of Regents Of The University Of Texas System | Computer-controlled miniature multileaf collimator |
| US5585724A (en) | 1995-06-12 | 1996-12-17 | Picker International, Inc. | Magnetic resonance gradient coils with interstitial gap |
| US6351659B1 (en) | 1995-09-28 | 2002-02-26 | Brainlab Med. Computersysteme Gmbh | Neuro-navigation system |
| GB9520564D0 (en) | 1995-10-07 | 1995-12-13 | Philips Electronics Nv | Apparatus for treating a patient |
| JPH09154961A (ja) | 1995-12-07 | 1997-06-17 | Toshiba Medical Eng Co Ltd | 放射線治療計画法 |
| US6260005B1 (en) | 1996-03-05 | 2001-07-10 | The Regents Of The University Of California | Falcon: automated optimization method for arbitrary assessment criteria |
| US5602892A (en) | 1996-03-21 | 1997-02-11 | Llacer; Jorge | Method for optimization of radiation therapy planning |
| US5675305A (en) | 1996-07-17 | 1997-10-07 | Picker International, Inc. | Multiple driven C magnet |
| US5851182A (en) | 1996-09-11 | 1998-12-22 | Sahadevan; Velayudhan | Megavoltage radiation therapy machine combined to diagnostic imaging devices for cost efficient conventional and 3D conformal radiation therapy with on-line Isodose port and diagnostic radiology |
| SE9603535D0 (sv) | 1996-09-27 | 1996-09-27 | Siemens Elema Ab | Undersökningsbord |
| AU5194698A (en) | 1996-10-24 | 1998-05-15 | Nomos Corporation | Planning method and apparatus for radiation dosimetry |
| US5757881A (en) | 1997-01-06 | 1998-05-26 | Siemens Business Communication Systems, Inc. | Redundant field-defining arrays for a radiation system |
| JP4040742B2 (ja) | 1997-03-28 | 2008-01-30 | 株式会社東芝 | Mri装置 |
| DE19715202B4 (de) | 1997-04-11 | 2006-02-02 | Brainlab Ag | Referenzierungsvorrichtung mit einem Mundstück |
| SE512603C2 (sv) | 1997-06-19 | 2000-04-10 | Elekta Ab | Metod och anordning för automatiserad dosplanering |
| US6157278A (en) | 1997-07-23 | 2000-12-05 | Odin Technologies Ltd. | Hybrid magnetic apparatus for use in medical applications |
| BE1012534A3 (fr) | 1997-08-04 | 2000-12-05 | Sumitomo Heavy Industries | Systeme de lit pour therapie par irradiation. |
| JP3519248B2 (ja) | 1997-08-08 | 2004-04-12 | 住友重機械工業株式会社 | 放射線治療用回転照射室 |
| JP3203211B2 (ja) | 1997-08-11 | 2001-08-27 | 住友重機械工業株式会社 | 水ファントム型線量分布測定装置及び放射線治療装置 |
| US6052430A (en) | 1997-09-25 | 2000-04-18 | Siemens Medical Systems, Inc. | Dynamic sub-space intensity modulation |
| US6526123B2 (en) | 1997-09-29 | 2003-02-25 | Moshe Ein-Gal | Multiple layer multileaf collimator |
| US6129670A (en) | 1997-11-24 | 2000-10-10 | Burdette Medical Systems | Real time brachytherapy spatial registration and visualization system |
| US6198957B1 (en) | 1997-12-19 | 2001-03-06 | Varian, Inc. | Radiotherapy machine including magnetic resonance imaging system |
| US5952830A (en) | 1997-12-22 | 1999-09-14 | Picker International, Inc. | Octapole magnetic resonance gradient coil system with elongate azimuthal gap |
| US6240162B1 (en) | 1998-01-15 | 2001-05-29 | Siemens Medical Systems, Inc. | Precision dosimetry in an intensity modulated radiation treatment system |
| US6083167A (en) | 1998-02-10 | 2000-07-04 | Emory University | Systems and methods for providing radiation therapy and catheter guides |
| US6327490B1 (en) | 1998-02-27 | 2001-12-04 | Varian Medical Systems, Inc. | Brachytherapy system for prostate cancer treatment with computer implemented systems and processes to facilitate pre-implantation planning and post-implantation evaluations with storage of multiple plan variations for a single patient |
| US6125335A (en) | 1998-04-10 | 2000-09-26 | Sun Nuclear Corporation | Wide field calibration of a multi-sensor array |
| US6487435B2 (en) | 1998-04-10 | 2002-11-26 | Wisconsin Alumni Research Foundation | Magnetic resonance angiography using undersampled 3D projection imaging |
| US6381486B1 (en) | 1999-01-08 | 2002-04-30 | Wisconsin Alumni Research Foundation | Magnetic resonance angiography with vessel segmentation |
| US6175761B1 (en) | 1998-04-21 | 2001-01-16 | Bechtel Bwxt Idaho, Llc | Methods and computer executable instructions for rapidly calculating simulated particle transport through geometrically modeled treatment volumes having uniform volume elements for use in radiotherapy |
| US6393096B1 (en) | 1998-05-27 | 2002-05-21 | Nomos Corporation | Planning method and apparatus for radiation dosimetry |
| US7096055B1 (en) | 1998-06-24 | 2006-08-22 | Achim Schweikard | Method to control delivery of radiation therapy |
| DE19829224B4 (de) | 1998-06-30 | 2005-12-15 | Brainlab Ag | Verfahren zur Lokalisation von Behandlungszielen im Bereich weicher Körperteile |
| US6311389B1 (en) | 1998-07-01 | 2001-11-06 | Kabushiki Kaisha Toshiba | Gradient magnetic coil apparatus and method of manufacturing the same |
| US6560311B1 (en) | 1998-08-06 | 2003-05-06 | Wisconsin Alumni Research Foundation | Method for preparing a radiation therapy plan |
| CA2339497C (en) | 1998-08-06 | 2003-10-07 | Wisconsin Alumni Research Foundation | Delivery modification system for radiation therapy |
| US6600810B1 (en) | 1998-08-10 | 2003-07-29 | Siemens Medical Solutions Usa, Inc. | Multiple layer multileaf collimator design to improve resolution and reduce leakage |
| US6112112A (en) | 1998-09-18 | 2000-08-29 | Arch Development Corporation | Method and system for the assessment of tumor extent in magnetic resonance images |
| DE19848765C2 (de) | 1998-10-22 | 2000-12-21 | Brainlab Med Computersyst Gmbh | Positionsverifizierung in Kamerabildern |
| US6980679B2 (en) | 1998-10-23 | 2005-12-27 | Varian Medical System Technologies, Inc. | Method and system for monitoring breathing activity of a subject |
| US6937696B1 (en) | 1998-10-23 | 2005-08-30 | Varian Medical Systems Technologies, Inc. | Method and system for predictive physiological gating |
| US6621889B1 (en) | 1998-10-23 | 2003-09-16 | Varian Medical Systems, Inc. | Method and system for predictive physiological gating of radiation therapy |
| US6241671B1 (en) | 1998-11-03 | 2001-06-05 | Stereotaxis, Inc. | Open field system for magnetic surgery |
| US6591127B1 (en) | 1999-03-15 | 2003-07-08 | General Electric Company | Integrated multi-modality imaging system and method |
| US6778850B1 (en) | 1999-03-16 | 2004-08-17 | Accuray, Inc. | Frameless radiosurgery treatment system and method |
| US6501981B1 (en) | 1999-03-16 | 2002-12-31 | Accuray, Inc. | Apparatus and method for compensating for respiratory and patient motions during treatment |
| US6144875A (en) | 1999-03-16 | 2000-11-07 | Accuray Incorporated | Apparatus and method for compensating for respiratory and patient motion during treatment |
| WO2000059576A1 (en) | 1999-04-02 | 2000-10-12 | Wisconsin Alumni Research Foundation | Megavoltage computed tomography during radiotherapy |
| DE19917867B4 (de) | 1999-04-20 | 2005-04-21 | Brainlab Ag | Verfahren und Vorrichtung zur Bildunterstützung bei der Behandlung von Behandlungszielen mit Integration von Röntgenerfassung und Navigationssystem |
| WO2000066223A1 (en) | 1999-05-03 | 2000-11-09 | Franz Krispel | Rotating stereotactic treatment system |
| US6459769B1 (en) | 1999-05-03 | 2002-10-01 | Sherwood Services Ag | Movable miniature multi-leaf collimator |
| JP3530072B2 (ja) | 1999-05-13 | 2004-05-24 | 三菱電機株式会社 | 放射線治療用の放射線照射装置の制御装置 |
| US6278891B1 (en) * | 1999-08-25 | 2001-08-21 | Echo Medical Systems, Llc | Nuclear magnetic resonance method and apparatus for bone analysis and imaging |
| DE19944516B4 (de) | 1999-09-16 | 2006-08-17 | Brainlab Ag | Dreidimensionale Formerfassung mit Kamerabildern |
| DE19953177A1 (de) | 1999-11-04 | 2001-06-21 | Brainlab Ag | Exakte Patientenpositionierung durch Vergleich von rekonstruierten und Linac-Röntgenbildern |
| US6546073B1 (en) | 1999-11-05 | 2003-04-08 | Georgia Tech Research Corporation | Systems and methods for global optimization of treatment planning for external beam radiation therapy |
| US7046762B2 (en) | 1999-11-05 | 2006-05-16 | Georgia Tech Research Corporation | Systems and methods for global optimization of treatment planning for external beam radiation therapy |
| US6542767B1 (en) | 1999-11-09 | 2003-04-01 | Biotex, Inc. | Method and system for controlling heat delivery to a target |
| US6349129B1 (en) | 1999-12-08 | 2002-02-19 | Siemens Medical Solutions Usa, Inc. | System and method for defining radiation treatment intensity maps |
| US6314159B1 (en) | 1999-12-08 | 2001-11-06 | Siemens Medical Systems, Inc. | System and method for optimizing radiation treatment with an intensity modulating multi-leaf collimator |
| DE19959720B4 (de) | 1999-12-10 | 2005-02-24 | Siemens Ag | Verfahren zum Betrieb eines Magnetresonanztomographiegeräts |
| DE19964016B4 (de) | 1999-12-30 | 2005-06-23 | Brainlab Ag | Verfahren und Vorrichtung zur Positionierung eines Körpers mit einem Lagesensor zur Bestrahlung |
| DE10000937B4 (de) | 2000-01-12 | 2006-02-23 | Brainlab Ag | Intraoperative Navigationsaktualisierung |
| US20030155530A1 (en) | 2000-01-14 | 2003-08-21 | Nabil Adnani | Linac neutron therapy and imaging |
| US6567685B2 (en) | 2000-01-21 | 2003-05-20 | Kabushiki Kaisha Toshiba | Magnetic resonance imaging apparatus |
| US6954068B1 (en) | 2000-01-21 | 2005-10-11 | Kabushiki Kaisha Toshiba | Magnetic resonance imaging apparatus |
| US6556012B2 (en) | 2000-01-21 | 2003-04-29 | Kabushiki Kaisha Toshiba | Magnetic resonance imaging apparatus |
| US6725078B2 (en) | 2000-01-31 | 2004-04-20 | St. Louis University | System combining proton beam irradiation and magnetic resonance imaging |
| DE10006317C1 (de) | 2000-02-12 | 2001-08-16 | Bruker Ag Faellanden | Gekühlter NMR-Probenkopf mit thermischer Isolation der Meßprobe |
| AU2001247704A1 (en) | 2000-03-21 | 2001-10-15 | Bechtel Bwxt Idaho, Llc | Methods and computer readable medium for improved radiotherapy dosimetry planning |
| GB0007018D0 (en) | 2000-03-22 | 2000-05-10 | Akguen Ali | Magnetic resonance imaging apparatus and method |
| US6751495B2 (en) * | 2000-03-31 | 2004-06-15 | Brigham & Womens' Hospital | Method of fast and reliable tissue differentiation using diffusion-weighted magnetic resonance imaging |
| ATE377381T1 (de) * | 2000-03-31 | 2007-11-15 | Gen Hospital Corp | Diffusionsbildgebung von gewebe |
| ATE221344T1 (de) | 2000-04-05 | 2002-08-15 | Brainlab Ag | Referenzierung eines patienten in einem medizinischen navigationssystem mittels aufgestrahlter lichtpunkte |
| US6373250B1 (en) * | 2000-05-19 | 2002-04-16 | Ramot University Authority For Applied Research And Industrial Development Ltd. | Method of magnetic resonance imaging |
| US6636645B1 (en) | 2000-06-29 | 2003-10-21 | Eastman Kodak Company | Image processing method for reducing noise and blocking artifact in a digital image |
| DE10033063A1 (de) | 2000-07-07 | 2002-01-24 | Brainlab Ag | Verfahren zur atmungskompensierten Strahlenbehandlung |
| US6594516B1 (en) | 2000-07-18 | 2003-07-15 | Koninklijke Philips Electronics, N.V. | External patient contouring |
| US6466813B1 (en) | 2000-07-22 | 2002-10-15 | Koninklijke Philips Electronics N.V. | Method and apparatus for MR-based volumetric frameless 3-D interactive localization, virtual simulation, and dosimetric radiation therapy planning |
| US6757355B1 (en) | 2000-08-17 | 2004-06-29 | Siemens Medical Solutions Usa, Inc. | High definition radiation treatment with an intensity modulating multi-leaf collimator |
| US8565860B2 (en) | 2000-08-21 | 2013-10-22 | Biosensors International Group, Ltd. | Radioactive emission detector equipped with a position tracking system |
| US20030011451A1 (en) | 2000-08-22 | 2003-01-16 | Ehud Katznelson | Permanent magnet assemblies for use in medical applications |
| US6330300B1 (en) | 2000-08-23 | 2001-12-11 | Siemens Medical Solutions Usa, Inc. | High definition intensity modulating radiation therapy system and method |
| ES2180492T3 (es) | 2000-09-01 | 2003-02-16 | Brainlab Ag | Representacion antisolapamiento de datos en dos o tres dimensiones con desplazamiento de valores de pixels, minimizando la curvatura. |
| US6885886B2 (en) | 2000-09-11 | 2005-04-26 | Brainlab Ag | Method and system for visualizing a body volume and computer program product |
| US6504899B2 (en) | 2000-09-25 | 2003-01-07 | The Board Of Trustees Of The Leland Stanford Junior University | Method for selecting beam orientations in intensity modulated radiation therapy |
| US6719683B2 (en) | 2000-09-30 | 2004-04-13 | Brainlab Ag | Radiotherapy treatment planning with multiple inverse planning results |
| DE10051370A1 (de) | 2000-10-17 | 2002-05-02 | Brainlab Ag | Verfahren und Vorrichtung zur exakten Patientenpositionierung in der Strahlentherapie und Radiochirurgie |
| ES2325878T3 (es) | 2000-11-03 | 2009-09-23 | Eleme Medical Inc. | Sistema para el tratamiento de tejidos. |
| US6411675B1 (en) | 2000-11-13 | 2002-06-25 | Jorge Llacer | Stochastic method for optimization of radiation therapy planning |
| US6570475B1 (en) | 2000-11-20 | 2003-05-27 | Intermagnetics General Corp. | Split type magnetic resonance imaging magnet |
| EP1208796B1 (de) | 2000-11-22 | 2003-03-05 | BrainLAB AG | Verfahren zur Bestimmung der Lungenfüllung |
| US6414487B1 (en) | 2000-11-22 | 2002-07-02 | Philips Medical Systems (Cleveland), Inc. | Time and memory optimized method of acquiring and reconstructing multi-shot 3D MRI data |
| EP1208808B1 (de) | 2000-11-24 | 2003-06-18 | BrainLAB AG | Vorrichtung und Verfahren zur Navigation |
| US20030028090A1 (en) | 2000-12-20 | 2003-02-06 | Image-Guided Neurologics, Inc. | Method for dynamic characterization of density fields in a compound structure |
| US7308298B2 (en) | 2000-12-22 | 2007-12-11 | Kabushiki Kaisha Toshiba | Magnetic resonance imaging using MT pulse of which duration is shorter |
| JP2002186676A (ja) | 2000-12-22 | 2002-07-02 | Hitachi Medical Corp | 絞り装置および該絞り装置を用いた放射線治療装置 |
| US6564084B2 (en) | 2001-03-02 | 2003-05-13 | Draeger Medical, Inc. | Magnetic field shielding and detecting device and method thereof |
| ES2215813T3 (es) | 2001-03-05 | 2004-10-16 | Brainlab Ag | Metodo para crear o actualizar un plan de tratamiento de radiaciones. |
| EP1238684B1 (de) | 2001-03-05 | 2004-03-17 | BrainLAB AG | Verfahren zur Erstellung bzw. Aktualisierung eines Bestrahlungsplans |
| US7046831B2 (en) | 2001-03-09 | 2006-05-16 | Tomotherapy Incorporated | System and method for fusion-aligned reprojection of incomplete data |
| US6661870B2 (en) | 2001-03-09 | 2003-12-09 | Tomotherapy Incorporated | Fluence adjustment for improving delivery to voxels without reoptimization |
| US7054413B2 (en) | 2001-03-15 | 2006-05-30 | Siemens Medical Solutions Usa, Inc. | Rotatable multi-element beam shaping device |
| US6708054B2 (en) | 2001-04-12 | 2004-03-16 | Koninklijke Philips Electronics, N.V. | MR-based real-time radiation therapy oncology simulator |
| EP1260179B1 (de) | 2001-05-22 | 2003-03-26 | BrainLAB AG | Röntgenbildregistrierungseinrichtung mit einem medizinischen Navigationssystem |
| US20020193685A1 (en) | 2001-06-08 | 2002-12-19 | Calypso Medical, Inc. | Guided Radiation Therapy System |
| WO2002103580A2 (en) | 2001-06-15 | 2002-12-27 | Massachusetts Institute Of Technology | Adaptive mean estimation and normalization of data |
| US20020196965A1 (en) * | 2001-06-22 | 2002-12-26 | Wallace Edward S. | Image transformation and analysis system and method |
| US20030083901A1 (en) * | 2001-06-22 | 2003-05-01 | Bosch Juan P. | Process for providing dialysis and other treatments |
| JP2003024296A (ja) | 2001-07-04 | 2003-01-28 | Ge Medical Systems Global Technology Co Llc | 静磁界調整方法およびmri装置 |
| GB2382512A (en) | 2001-07-20 | 2003-05-28 | Elekta Oncology Syst Ltd | MRI in guided radiotherapy and position verification |
| US6690166B2 (en) * | 2001-09-26 | 2004-02-10 | Southwest Research Institute | Nuclear magnetic resonance technology for non-invasive characterization of bone porosity and pore size distributions |
| US6626264B1 (en) | 2001-10-30 | 2003-09-30 | Igt | Radio frequency shielded and acoustically insulated enclosure |
| US6810108B2 (en) | 2001-11-02 | 2004-10-26 | Siemens Medical Solutions Usa, Inc. | System and method for positioning an electronic portal imaging device |
| WO2003039370A1 (en) | 2001-11-05 | 2003-05-15 | Computerized Medical Systems, Inc. | Apparatus and method for registration, guidance, and targeting of external beam radiation therapy |
| US6664879B2 (en) | 2001-12-04 | 2003-12-16 | Nmr Holdings No. 2 Pty Limited | Asymmetric tesseral shim coils for magnetic resonance |
| US7092573B2 (en) | 2001-12-10 | 2006-08-15 | Eastman Kodak Company | Method and system for selectively applying enhancement to an image |
| DE50101677D1 (de) | 2001-12-18 | 2004-04-15 | Brainlab Ag | Projektion von Patientenbilddaten aus Durchleuchtungs- bzw. Schichtbilderfassungsverfahren auf Videobilder |
| US7221733B1 (en) | 2002-01-02 | 2007-05-22 | Varian Medical Systems Technologies, Inc. | Method and apparatus for irradiating a target |
| US6657391B2 (en) | 2002-02-07 | 2003-12-02 | Siemens Medical Solutions Usa, Inc. | Apparatus and method for establishing a Q-factor of a cavity for an accelerator |
| AU2003213771A1 (en) | 2002-03-06 | 2003-09-22 | Tomotherapy Incorporated | Method for modification of radiotherapy treatment delivery |
| DE10211244A1 (de) | 2002-03-13 | 2003-10-23 | Lactec Ges Fuer Moderne Lackte | Lackieranlage zum Aufbringen von flüssigem Beschichtungsmaterial |
| US20030181804A1 (en) | 2002-03-20 | 2003-09-25 | Koninklijke Philips Electronics N.V. | Distributed diagnostic imaging systems |
| US6630829B1 (en) | 2002-04-22 | 2003-10-07 | Ge Medical Systems Global Technology Co., Llc | Gradient coil set capable of producing a variable field of view |
| JP3920140B2 (ja) * | 2002-05-13 | 2007-05-30 | 株式会社東芝 | Mri装置及びフロー定量化装置 |
| FR2839894A1 (fr) | 2002-05-21 | 2003-11-28 | Chabunda Christophe Mwanza | Procedes, appareils de cyclotherapie image-guidee et mode d'obtention d'images scanographiques diagnostiques instantanees pour la planification et la dosimetrie en ligne |
| US6735277B2 (en) | 2002-05-23 | 2004-05-11 | Koninklijke Philips Electronics N.V. | Inverse planning for intensity-modulated radiotherapy |
| US6728336B2 (en) | 2002-07-12 | 2004-04-27 | General Hospital Corporation | Arrangements and methods for treating a subject |
| US7162005B2 (en) | 2002-07-19 | 2007-01-09 | Varian Medical Systems Technologies, Inc. | Radiation sources and compact radiation scanning systems |
| GB2393373A (en) | 2002-09-13 | 2004-03-24 | Elekta Ab | MRI in guided radiotherapy and position verification |
| US6853704B2 (en) | 2002-09-23 | 2005-02-08 | Siemens Medical Solutions Usa, Inc. | System providing multiple focused radiation beams |
| US7227925B1 (en) | 2002-10-02 | 2007-06-05 | Varian Medical Systems Technologies, Inc. | Gantry mounted stereoscopic imaging system |
| US7289599B2 (en) | 2002-10-04 | 2007-10-30 | Varian Medical Systems Technologies, Inc. | Radiation process and apparatus |
| US7657304B2 (en) | 2002-10-05 | 2010-02-02 | Varian Medical Systems, Inc. | Imaging device for radiation treatment applications |
| KR20050059245A (ko) | 2002-10-07 | 2005-06-17 | 노모스 코포레이션 | 타겟 위치 확인 방법 및 장치 |
| WO2004036738A2 (en) | 2002-10-16 | 2004-04-29 | Varian Medical Systems Technologies, Inc. | Method and apparatus for excess signal correction in an imager |
| US7260426B2 (en) | 2002-11-12 | 2007-08-21 | Accuray Incorporated | Method and apparatus for tracking an internal target region without an implanted fiducial |
| EP1565760A1 (en) | 2002-11-20 | 2005-08-24 | Koninklijke Philips Electronics N.V. | Self-shielded gradient field coil for magnetic resonance imaging |
| US20040106869A1 (en) | 2002-11-29 | 2004-06-03 | Ron-Tech Medical Ltd. | Ultrasound tracking device, system and method for intrabody guiding procedures |
| US7317782B2 (en) | 2003-01-31 | 2008-01-08 | Varian Medical Systems Technologies, Inc. | Radiation scanning of cargo conveyances at seaports and the like |
| US20050143965A1 (en) | 2003-03-14 | 2005-06-30 | Failla Gregory A. | Deterministic computation of radiation doses delivered to tissues and organs of a living organism |
| US20040254448A1 (en) | 2003-03-24 | 2004-12-16 | Amies Christopher Jude | Active therapy redefinition |
| CN100507593C (zh) | 2003-03-25 | 2009-07-01 | 西门子公司 | 磁场发生器及带有该磁场发生器的磁共振设备 |
| US7570987B2 (en) | 2003-04-04 | 2009-08-04 | Brainlab Ag | Perspective registration and visualization of internal areas of the body |
| US20110142887A1 (en) * | 2009-12-15 | 2011-06-16 | Immunovative Therapies Ltd. | Methods and compositions for liquidation of tumors |
| US6788060B1 (en) | 2003-05-28 | 2004-09-07 | Ge Medical Systems Global Technology Co., Inc. | Imaging system with homogeneous magnetic field |
| US7542622B1 (en) | 2003-06-02 | 2009-06-02 | The Trustees Of Columbia University In The City Of New York | Spatio-temporal treatment of noisy images using brushlets |
| US7171257B2 (en) | 2003-06-11 | 2007-01-30 | Accuray Incorporated | Apparatus and method for radiosurgery |
| US7778691B2 (en) | 2003-06-13 | 2010-08-17 | Wisconsin Alumni Research Foundation | Apparatus and method using synchronized breathing to treat tissue subject to respiratory motion |
| US7412029B2 (en) | 2003-06-25 | 2008-08-12 | Varian Medical Systems Technologies, Inc. | Treatment planning, simulation, and verification system |
| GB2403884B (en) | 2003-07-08 | 2006-03-01 | Elekta Ab | Multi-leaf collimator |
| US7266175B1 (en) | 2003-07-11 | 2007-09-04 | Nomos Corporation | Planning method for radiation therapy |
| WO2005010711A2 (en) | 2003-07-21 | 2005-02-03 | Johns Hopkins University | Robotic 5-dimensional ultrasound |
| US7463823B2 (en) | 2003-07-24 | 2008-12-09 | Brainlab Ag | Stereoscopic visualization device for patient image data and video images |
| US7015692B2 (en) | 2003-08-07 | 2006-03-21 | Ge Electric Company | Apparatus for active cooling of an MRI patient bore in cylindrical MRI systems |
| US7204640B2 (en) | 2003-08-29 | 2007-04-17 | Accuray, Inc. | Apparatus and method for registering 2D radiographic images with images reconstructed from 3D scan data |
| US8571639B2 (en) | 2003-09-05 | 2013-10-29 | Varian Medical Systems, Inc. | Systems and methods for gating medical procedures |
| US20050053267A1 (en) | 2003-09-05 | 2005-03-10 | Varian Medical Systems Technologies, Inc. | Systems and methods for tracking moving targets and monitoring object positions |
| US6999555B2 (en) | 2003-09-15 | 2006-02-14 | Varian Medical Systems Imaging Laboratory Gmbh | Systems and methods for processing data |
| US7315636B2 (en) | 2003-09-18 | 2008-01-01 | Accuray, Inc. | Generation of reconstructed images |
| US7343192B2 (en) * | 2003-09-23 | 2008-03-11 | Echo Medical Systems, Llc | Magnetic resonance imaging method and apparatus for body composition analysis |
| EP1673146B1 (en) | 2003-09-30 | 2012-11-14 | Koninklijke Philips Electronics N.V. | Target tracking apparatus for radiation treatment planning and delivery |
| US7053617B2 (en) | 2003-10-01 | 2006-05-30 | General Electric Co. | Integrated electronic RF shielding apparatus for an MRI magnet |
| EA010207B1 (ru) * | 2003-10-07 | 2008-06-30 | Номос Корпорейшн | Система планирования, способ и устройство для конформной радиотерапии |
| US6906606B2 (en) | 2003-10-10 | 2005-06-14 | General Electric Company | Magnetic materials, passive shims and magnetic resonance imaging systems |
| US7002408B2 (en) | 2003-10-15 | 2006-02-21 | Varian Medical Systems Technologies, Inc. | Data signal amplifier and processor with multiple signal gains for increased dynamic signal range |
| US7589326B2 (en) | 2003-10-15 | 2009-09-15 | Varian Medical Systems Technologies, Inc. | Systems and methods for image acquisition |
| US7154991B2 (en) | 2003-10-17 | 2006-12-26 | Accuray, Inc. | Patient positioning assembly for therapeutic radiation system |
| US20070197908A1 (en) | 2003-10-29 | 2007-08-23 | Ruchala Kenneth J | System and method for calibrating and positioning a radiation therapy treatment table |
| WO2005047919A1 (en) | 2003-11-12 | 2005-05-26 | Invivo Corporation | Method for generating fast magnetic resonance images |
| CA2552976A1 (en) | 2003-12-12 | 2005-06-30 | Philometron, Inc. | Multiple section parenteral drug delivery apparatus |
| GB2409521B (en) | 2003-12-22 | 2007-04-18 | Ge Med Sys Global Tech Co Llc | Gradient coil apparatus and method of assembly thereof |
| WO2005072825A1 (en) | 2004-01-20 | 2005-08-11 | University Of Florida Research Foundation, Inc. | Radiation therapy system using interior-point methods and convex models for intensity modulated fluence map optimization |
| US7230429B1 (en) | 2004-01-23 | 2007-06-12 | Invivo Corporation | Method for applying an in-painting technique to correct images in parallel imaging |
| WO2005077263A2 (en) * | 2004-02-06 | 2005-08-25 | Wake Forest University Health Services | Non-invasive imaging for determining global tissue characteristics |
| EP1563799B2 (de) | 2004-02-11 | 2012-11-28 | BrainLAB AG | Verstellbare Markeranordnung |
| US7853308B2 (en) | 2004-02-17 | 2010-12-14 | Siemens Medical Solutions Usa, Inc. | System and method for patient positioning for radiotherapy in the presence of respiratory motion |
| JP5110881B2 (ja) | 2004-02-20 | 2012-12-26 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイティド | 軟組織を同時に画像化しながら等角放射線治療を送達するためのシステム |
| US8263938B2 (en) | 2004-03-01 | 2012-09-11 | Varian Medical Systems, Inc. | Dual energy radiation scanning of objects |
| US7477776B2 (en) | 2004-03-01 | 2009-01-13 | Brainlab Ag | Method and apparatus for determining a plane of symmetry of a three-dimensional object |
| CN1669599A (zh) | 2004-03-16 | 2005-09-21 | 上海英迈吉东影图像设备有限公司 | 三维适形放射治疗剂量计划方法 |
| JP4392280B2 (ja) | 2004-03-26 | 2009-12-24 | 株式会社日立製作所 | 放射性同位元素製造装置および放射性薬剤製造装置 |
| US7046765B2 (en) | 2004-03-31 | 2006-05-16 | Accuray, Inc. | Radiosurgery x-ray system with collision avoidance subsystem |
| US7166852B2 (en) | 2004-04-06 | 2007-01-23 | Accuray, Inc. | Treatment target positioning system |
| WO2005096788A2 (en) | 2004-04-08 | 2005-10-20 | University Of Florida Research Foundation, Inc. | Field splitting for intensity modulated fields of large size |
| ITSV20040016A1 (it) | 2004-04-13 | 2004-07-13 | Esaote Spa | Macchina per risonanza magnetico nucleare |
| WO2005115544A1 (en) | 2004-05-24 | 2005-12-08 | University Of Virginia Patent Foundation | System and method for temporally precise intensity modulated radiation therapy (imrt) |
| US7130372B2 (en) | 2004-06-08 | 2006-10-31 | Siemens Medical Solutions Usa, Inc. | Linear accelerator with X-ray imaging elements mounted on curved support |
| US20060017411A1 (en) | 2004-06-17 | 2006-01-26 | Accsys Technology, Inc. | Mobile/transportable PET radioisotope system with omnidirectional self-shielding |
| US7327865B2 (en) | 2004-06-30 | 2008-02-05 | Accuray, Inc. | Fiducial-less tracking with non-rigid image registration |
| US7366278B2 (en) | 2004-06-30 | 2008-04-29 | Accuray, Inc. | DRR generation using a non-linear attenuation model |
| US7426318B2 (en) | 2004-06-30 | 2008-09-16 | Accuray, Inc. | Motion field generation for non-rigid image registration |
| US7231076B2 (en) | 2004-06-30 | 2007-06-12 | Accuray, Inc. | ROI selection in image registration |
| US7522779B2 (en) | 2004-06-30 | 2009-04-21 | Accuray, Inc. | Image enhancement method and system for fiducial-less tracking of treatment targets |
| EP1623738B1 (de) | 2004-08-06 | 2007-09-12 | BrainLAB AG | Volumetrische Bildgebung an einem Strahlentherapiegerät |
| US7634122B2 (en) | 2004-08-25 | 2009-12-15 | Brainlab Ag | Registering intraoperative scans |
| US20060058636A1 (en) | 2004-09-13 | 2006-03-16 | Wemple Charles A | Method for tracking the movement of a particle through a geometric model for use in radiotherapy |
| US7012385B1 (en) | 2004-09-24 | 2006-03-14 | Viara Research, Llc | Multi-channel induction accelerator with external channels |
| US7302038B2 (en) | 2004-09-24 | 2007-11-27 | Wisconsin Alumni Research Foundation | Correction of patient rotation errors in radiotherapy using couch translation |
| US8989349B2 (en) | 2004-09-30 | 2015-03-24 | Accuray, Inc. | Dynamic tracking of moving targets |
| US7298819B2 (en) | 2004-09-30 | 2007-11-20 | Accuray Incorporated | Flexible treatment planning |
| US7471813B2 (en) | 2004-10-01 | 2008-12-30 | Varian Medical Systems International Ag | Systems and methods for correction of scatter in images |
| US7415095B2 (en) | 2004-10-01 | 2008-08-19 | Siemens Aktiengesellschaft | System and method utilizing adaptive radiation therapy framework |
| US7505037B2 (en) | 2004-10-02 | 2009-03-17 | Accuray, Inc. | Direct volume rendering of 4D deformable volume images |
| EP1645241B1 (de) | 2004-10-05 | 2011-12-28 | BrainLAB AG | Positionsmarkersystem mit Punktlichtquellen |
| WO2006047580A2 (en) | 2004-10-26 | 2006-05-04 | Univ California | System and method for providing a rotating magnetic field |
| US8014625B2 (en) | 2004-11-10 | 2011-09-06 | Agfa Healthcare | Method of performing measurements on digital images |
| US20080108894A1 (en) * | 2004-11-15 | 2008-05-08 | Elgavish Gabriel A | Methods and Systems of Analyzing Clinical Parameters and Methods of Producing Visual Images |
| JP3983759B2 (ja) | 2004-11-26 | 2007-09-26 | 株式会社日立メディコ | 核磁気共鳴撮像装置 |
| DE102004061509B4 (de) | 2004-12-21 | 2007-02-08 | Siemens Ag | Verfahren und Gerät zur beschleunigten Spiral-kodierten Bildgebung in der Magnetresonanztomographie |
| US20060170679A1 (en) | 2005-02-01 | 2006-08-03 | Hongwu Wang | Representing a volume of interest as boolean combinations of multiple simple contour sets |
| US7957507B2 (en) | 2005-02-28 | 2011-06-07 | Cadman Patrick F | Method and apparatus for modulating a radiation beam |
| US20080164878A1 (en) | 2005-03-17 | 2008-07-10 | Koninklijke Philips Electronics N. V. | Minimum Energy Shim Coils For Magnetic Resonance |
| GB2424281A (en) | 2005-03-17 | 2006-09-20 | Elekta Ab | Radiotherapeutic Apparatus with MRI |
| US8295577B2 (en) | 2005-03-31 | 2012-10-23 | Michael Zarkh | Method and apparatus for guiding a device in a totally occluded or partly occluded tubular organ |
| WO2006114003A1 (en) * | 2005-04-27 | 2006-11-02 | The Governors Of The University Of Alberta | A method and system for automatic detection and segmentation of tumors and associated edema (swelling) in magnetic resonance (mri) images |
| WO2007018646A1 (en) | 2005-04-29 | 2007-02-15 | Varian Medical Systems Technologies, Inc. | Radiation treatment systems and components thereof |
| US7379531B2 (en) | 2005-06-13 | 2008-05-27 | Siemens Medical Solutions Health Services Corporation | Beam therapy treatment user interface monitoring and recording system |
| US20070016014A1 (en) | 2005-06-15 | 2007-01-18 | Kenji Hara | Radio therapy apparatus and operating method of the same |
| US7349522B2 (en) | 2005-06-22 | 2008-03-25 | Board Of Trustees Of The University Of Arkansas | Dynamic radiation therapy simulation system |
| WO2007007276A2 (en) | 2005-07-14 | 2007-01-18 | Koninklijke Philips Electronics | Method of accounting for tumor motion in radiotherapy treatment |
| KR20080039925A (ko) | 2005-07-22 | 2008-05-07 | 토모테라피 인코포레이티드 | 생물학적 모델에 기초하여 방사선 요법 치료 계획을적합화시키는 방법 및 시스템 |
| CA2616301A1 (en) | 2005-07-22 | 2007-02-01 | Tomotherapy Incorporated | Method and system for evaluating delivered dose |
| US8406851B2 (en) | 2005-08-11 | 2013-03-26 | Accuray Inc. | Patient tracking using a virtual image |
| US20070083114A1 (en) | 2005-08-26 | 2007-04-12 | The University Of Connecticut | Systems and methods for image resolution enhancement |
| JP4386288B2 (ja) | 2005-08-31 | 2009-12-16 | 株式会社日立製作所 | 放射線治療装置の位置決めシステム及び位置決め方法 |
| EP1760481B1 (en) | 2005-09-03 | 2010-05-19 | Bruker BioSpin AG | Matrix shim system with grouped coils |
| US7266176B2 (en) | 2005-09-28 | 2007-09-04 | Accuray Incorporated | Workspace optimization for radiation treatment delivery system |
| US7295649B2 (en) | 2005-10-13 | 2007-11-13 | Varian Medical Systems Technologies, Inc. | Radiation therapy system and method of using the same |
| CN101378805B (zh) | 2005-10-17 | 2013-03-27 | 艾伯塔健康服务中心 | 集成的体外射束放射治疗和mri系统 |
| US8073102B2 (en) | 2005-10-17 | 2011-12-06 | Alberta Health Services | Real-time dose reconstruction using dynamic simulation and image guided adaptive radiotherapy |
| US7977942B2 (en) | 2005-11-16 | 2011-07-12 | Board Of Regents, The University Of Texas System | Apparatus and method for tracking movement of a target |
| EP1949404B1 (en) | 2005-11-18 | 2016-06-29 | Mevion Medical Systems, Inc. | Charged particle radiation therapy |
| US8041103B2 (en) | 2005-11-18 | 2011-10-18 | Kla-Tencor Technologies Corp. | Methods and systems for determining a position of inspection data in design data space |
| EP1818078A1 (en) | 2006-02-09 | 2007-08-15 | DKFZ Deutsches Krebsforschungszentrum | Inverse treatment planning method |
| CA2646363C (en) | 2006-03-14 | 2015-07-21 | The Johns Hopkins University | Apparatus for insertion of a medical device within a body during a medical imaging process and devices and methods related thereto |
| DE112007000801T5 (de) | 2006-03-28 | 2009-02-12 | Hampton University | Hadronen-Behandlungsplanung mit adäquater biologischer Gewichtung |
| US7907772B2 (en) | 2006-03-30 | 2011-03-15 | Accuray Incorporated | Delineation on three-dimensional medical image |
| US7902530B1 (en) | 2006-04-06 | 2011-03-08 | Velayudhan Sahadevan | Multiple medical accelerators and a kV-CT incorporated radiation therapy device and semi-automated custom reshapeable blocks for all field synchronous image guided 3-D-conformal-intensity modulated radiation therapy |
| US7532705B2 (en) | 2006-04-10 | 2009-05-12 | Duke University | Systems and methods for localizing a target for radiotherapy based on digital tomosynthesis |
| US7605589B2 (en) | 2006-04-10 | 2009-10-20 | Bruker Biospin Ag | Method for automatic shimming for nuclear magnetic resonance spectroscopy |
| US7840045B2 (en) | 2006-04-21 | 2010-11-23 | The University Of Utah Research Foundation | Method and system for parallel reconstruction in the K-space domain for application in imaging systems |
| US8073104B2 (en) | 2006-05-25 | 2011-12-06 | William Beaumont Hospital | Portal and real time imaging for treatment verification |
| CA2905989C (en) | 2006-05-25 | 2017-01-24 | Di Yan | Real-time, on-line and offline treatment dose tracking and feedback process for volumetric image guided adaptive radiotherapy |
| US7610079B2 (en) | 2006-07-25 | 2009-10-27 | Ast Gmbh | Shock wave imaging system |
| US7505559B2 (en) | 2006-08-25 | 2009-03-17 | Accuray Incorporated | Determining a target-to-surface distance and using it for real time absorbed dose calculation and compensation |
| EP2081494B1 (en) | 2006-11-16 | 2018-07-11 | Vanderbilt University | System and method of compensating for organ deformation |
| CN100380406C (zh) | 2006-12-29 | 2008-04-09 | 四川大学 | 放射治疗计划系统中获得三维解剖结构投影轮廓线的方法 |
| JP5209277B2 (ja) | 2007-01-17 | 2013-06-12 | 株式会社東芝 | 傾斜磁場コイルユニット、mri装置用ガントリ、及びmri装置 |
| US8460195B2 (en) | 2007-01-19 | 2013-06-11 | Sunnybrook Health Sciences Centre | Scanning mechanisms for imaging probe |
| KR101517252B1 (ko) | 2007-01-19 | 2015-05-04 | 써니브룩 헬스 사이언시즈 센터 | 영상 탐침 장치의 스캐닝 메카니즘 |
| US7602183B2 (en) | 2007-02-13 | 2009-10-13 | The Board Of Trustees Of The Leland Stanford Junior University | K-T sparse: high frame-rate dynamic magnetic resonance imaging exploiting spatio-temporal sparsity |
| DE102008007245B4 (de) | 2007-02-28 | 2010-10-14 | Siemens Aktiengesellschaft | Kombiniertes Strahlentherapie- und Magnetresonanzgerät |
| US20080235052A1 (en) | 2007-03-19 | 2008-09-25 | General Electric Company | System and method for sharing medical information between image-guided surgery systems |
| US8155417B2 (en) | 2007-03-27 | 2012-04-10 | Hologic, Inc. | Post-acquisition adaptive reconstruction of MRI data |
| CN101688908B (zh) | 2007-04-04 | 2014-02-12 | 皇家飞利浦电子股份有限公司 | 分离式梯度线圈及使用该梯度线圈的pet/mri混合系统 |
| JP2010158258A (ja) * | 2007-04-11 | 2010-07-22 | Konica Minolta Medical & Graphic Inc | 軟部組織評価システム |
| US7489131B2 (en) | 2007-04-23 | 2009-02-10 | General Electric Co. | System and apparatus for direct cooling of gradient coils |
| US7898192B2 (en) | 2007-06-06 | 2011-03-01 | Siemens Medical Solutions Usa, Inc. | Modular linac and systems to support same |
| WO2009004521A2 (en) | 2007-07-02 | 2009-01-08 | Koninklijke Philips Electronics N.V. | Thermally stabilized pet detector for hybrid pet-mr system |
| AU2008274922B2 (en) * | 2007-07-11 | 2014-04-03 | Board Of Regents, The University Of Texas System | Seeds and markers for use in imaging |
| US8570042B2 (en) | 2007-08-31 | 2013-10-29 | The Regents Of The University Of California | Adjustable permanent magnet assembly for NMR and MRI |
| US7791338B2 (en) | 2007-09-07 | 2010-09-07 | The Board Of Trustees Of The Leland Stanford Junior University | MRI method of determining time-optimal gradient waveforms with gradient amplitude as a function of arc-length in k-space |
| US8315689B2 (en) | 2007-09-24 | 2012-11-20 | MRI Interventions, Inc. | MRI surgical systems for real-time visualizations using MRI image data and predefined data of surgical tools |
| EP2050395A1 (en) | 2007-10-18 | 2009-04-22 | Paracelsus Medizinische Privatuniversität | Methods for improving image quality of image detectors, and systems therefor |
| CN101820948A (zh) * | 2007-10-25 | 2010-09-01 | 断层放疗公司 | 用于放疗实施的运动适应性优化的系统和方法 |
| CN101452065B (zh) | 2007-12-04 | 2011-10-19 | 西门子(中国)有限公司 | 磁共振设备中的局部线圈、磁共振设备以及成像方法 |
| US7801271B2 (en) | 2007-12-23 | 2010-09-21 | Oraya Therapeutics, Inc. | Methods and devices for orthovoltage ocular radiotherapy and treatment planning |
| US8238516B2 (en) | 2008-01-09 | 2012-08-07 | Kabushiki Kaisha Toshiba | Radiotherapy support apparatus |
| JP5197025B2 (ja) | 2008-01-09 | 2013-05-15 | 株式会社東芝 | 放射線治療システム、放射線治療支援装置及び放射線治療支援プログラム |
| JP5197026B2 (ja) | 2008-01-09 | 2013-05-15 | 株式会社東芝 | 放射線治療システム、放射線治療支援装置及び放射線治療支援プログラム |
| JP5390539B2 (ja) | 2008-02-25 | 2014-01-15 | コーニンクレッカ フィリップス エヌ ヴェ | 放射線検出器に対する等角面のバックボーン |
| EP2262570A1 (en) | 2008-03-12 | 2010-12-22 | Navotek Medical Ltd. | Combination mri and radiotherapy systems and methods of use |
| US7741624B1 (en) | 2008-05-03 | 2010-06-22 | Velayudhan Sahadevan | Single session interactive ultra-short duration super-high biological dose rate radiation therapy and radiosurgery |
| CN102036712B (zh) | 2008-05-08 | 2015-02-25 | 约翰霍普金斯大学 | 用于放射治疗的系统和确定放射治疗参数的方法 |
| JP5497750B2 (ja) | 2008-05-22 | 2014-05-21 | エゴロヴィチ バラキン、ウラジミール | 荷電粒子癌治療システムと併用されるx線方法及び装置 |
| CA2728111C (en) | 2008-06-24 | 2017-09-19 | Alberta Health Services | Radiation therapy system |
| US7659718B1 (en) | 2008-07-31 | 2010-02-09 | The Board Of Trustees Of The Leland Stanford Junior University | Blip design for random sampling compressed sensing of flyback 3D-MRSI |
| US8295906B2 (en) | 2008-08-20 | 2012-10-23 | Imris Inc | MRI guided radiation therapy |
| EP2196240A1 (en) | 2008-12-12 | 2010-06-16 | Koninklijke Philips Electronics N.V. | Therapeutic apparatus |
| US8350234B2 (en) | 2008-12-24 | 2013-01-08 | Mitsubishi Electric Corporation | Particle beam therapy system |
| JP2010148833A (ja) * | 2008-12-26 | 2010-07-08 | Hitachi Ltd | 粒子線照射装置及び粒子線照射方法 |
| US8310233B2 (en) | 2009-02-18 | 2012-11-13 | Mayo Foundation For Medical Education And Research | Method for image reconstruction from undersampled medical imaging data |
| WO2010103644A1 (ja) | 2009-03-12 | 2010-09-16 | 独立行政法人放射線医学総合研究所 | オープンpet/mri複合機 |
| US8331531B2 (en) | 2009-03-13 | 2012-12-11 | The Board Of Trustees Of The Leland Stanford Junior University | Configurations for integrated MRI-linear accelerators |
| EP2230530A1 (en) | 2009-03-20 | 2010-09-22 | Koninklijke Philips Electronics N.V. | A tesseral shim coil for a magnetic resonance system |
| RU2541887C2 (ru) | 2009-04-02 | 2015-02-20 | Конинклейке Филипс Электроникс Н.В. | Автоматизированное оконтуривание анатомии для планирования терапии с управлением по изображениям |
| WO2010125486A1 (en) | 2009-04-28 | 2010-11-04 | Koninklijke Philips Electronics N.V. | Interventional mr imaging with motion compensation |
| JP2010269067A (ja) | 2009-05-25 | 2010-12-02 | Hitachi Medical Corp | 治療支援装置 |
| WO2010138659A1 (en) * | 2009-05-27 | 2010-12-02 | Ptc Therapeutics, Inc. | Methods for treating brain tumors |
| WO2010144405A2 (en) | 2009-06-08 | 2010-12-16 | Surgivision, Inc. | Mri-guided surgical systems with proximity alerts |
| AU2010262843B2 (en) | 2009-06-19 | 2015-07-16 | Viewray Technologies, Inc. | System and method for performing tomographic image acquisition and reconstruction |
| US8139714B1 (en) | 2009-06-25 | 2012-03-20 | Velayudhan Sahadevan | Few seconds beam on time, breathing synchronized image guided all fields simultaneous radiation therapy combined with hyperthermia |
| CN102472830B (zh) | 2009-07-15 | 2016-03-30 | 微雷公司 | 用于使直线性加速器和磁共振成像设备彼此屏蔽的方法和装置 |
| DE102009035951B4 (de) | 2009-08-03 | 2018-02-22 | Siemens Healthcare Gmbh | Bestimmung von Strahlparametern für asymmetrische Photonenstrahlen |
| EP2502096A4 (en) | 2009-11-20 | 2013-09-04 | Viewray Inc | SELF-SCREENING GRADIENT COIL |
| US8427148B2 (en) | 2009-12-31 | 2013-04-23 | Analogic Corporation | System for combining magnetic resonance imaging with particle-based radiation systems for image guided radiation therapy |
| US8173983B1 (en) | 2010-01-07 | 2012-05-08 | Velayudhan Sahadevan | All field simultaneous radiation therapy |
| US9694205B2 (en) | 2010-02-12 | 2017-07-04 | Elekta Ab (Publ) | Radiotherapy and imaging apparatus |
| US8803524B2 (en) | 2010-02-24 | 2014-08-12 | Viewray Incorporated | Split magnetic resonance imaging system |
| EP2569054A4 (en) | 2010-05-11 | 2013-10-02 | Hampton University Office Of General Counsel | DEVICE, METHOD AND SYSTEM FOR MEASURING PROMPT GAMMA OR OTHER RADIATION-INDUCED RADIATION DURING HADRONTHERAPY TREATMENTS FOR DOSAGE AND RANGE TESTING USES BY IONIZATION RADIATION RECOGNITION |
| EP2580698A1 (en) | 2010-06-11 | 2013-04-17 | Koninklijke Philips Electronics N.V. | Simultaneous multi-modality inverse optimization for radiotherapy treatment planning |
| EP2400314A1 (en) | 2010-06-14 | 2011-12-28 | Agilent Technologies U.K. Limited | Superconducting magnet arrangement and method of mounting thereof |
| DE102010032080B4 (de) | 2010-07-23 | 2012-09-27 | Siemens Aktiengesellschaft | Getriggerte Magnetresonanzbildgebung auf der Grundlage einer partiellen parallelen Akquisition (PPA) |
| US8637841B2 (en) | 2010-08-23 | 2014-01-28 | Varian Medical Systems, Inc. | Multi level multileaf collimators |
| JP2013543403A (ja) | 2010-10-05 | 2013-12-05 | サトヤパル ラティ、 | 画像誘導放射線治療システム及びそれに用いる遮蔽された高周波検出コイル |
| JP5700880B2 (ja) * | 2010-10-14 | 2015-04-15 | シンセティックエムアール・エイビイ | 複数の磁気共鳴物理的パラメータを脳内のミエリン含量に関連付けるための方法及び装置 |
| CN103210318B (zh) | 2010-11-09 | 2019-04-23 | 皇家飞利浦电子股份有限公司 | 具有至少两个发射和接收信道的磁共振成像以及放射治疗设备 |
| US9151815B2 (en) | 2010-11-15 | 2015-10-06 | Kabushiki Kaisha Toshiba | Magnetic resonance imaging apparatus and magnetic resonance imaging method |
| WO2012080894A2 (en) | 2010-12-13 | 2012-06-21 | Koninklijke Philips Electronics N.V. | Therapeutic apparatus comprising a radiotherapy apparatus, a mechanical positioning system, and a magnetic resonance imaging system |
| WO2012088321A1 (en) | 2010-12-22 | 2012-06-28 | Viewray Incorporated | System and method for image guidance during medical procedures |
| US8565377B2 (en) | 2011-03-07 | 2013-10-22 | Dalhousie University | Methods and apparatus for imaging in conjunction with radiotherapy |
| EP2500909A1 (en) | 2011-03-16 | 2012-09-19 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Position sensoring method and system for a multi-leaf collimator |
| US9254112B2 (en) | 2011-03-23 | 2016-02-09 | Siemens Corporation | Respiratory interval-based correlation and processing of dynamic imaging data |
| DE102011006582A1 (de) | 2011-03-31 | 2012-10-04 | Siemens Aktiengesellschaft | Strahlentherapieanlage mit Hochfrequenzschirmung |
| JP5701671B2 (ja) | 2011-04-27 | 2015-04-15 | 住友重機械工業株式会社 | 荷電粒子線照射装置 |
| JP6018185B2 (ja) | 2011-05-31 | 2016-11-02 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | Mri放射線治療装置の静磁場補正 |
| US20130066135A1 (en) | 2011-08-29 | 2013-03-14 | Louis Rosa | Neutron irradiation therapy device |
| US20130086163A1 (en) | 2011-10-04 | 2013-04-04 | Siemens Medical Solutions Usa, Inc. | Healthcare Information System Interface Supporting Social Media and Related Applications |
| US9789337B2 (en) | 2011-10-07 | 2017-10-17 | Siemens Medical Solutions Usa, Inc. | Combined imaging modalities for radiation treatment planning |
| US8981779B2 (en) | 2011-12-13 | 2015-03-17 | Viewray Incorporated | Active resistive shimming fro MRI devices |
| BR112014019362A8 (pt) | 2012-02-09 | 2017-07-11 | Koninklijke Philips Nv | Dispositivo de detecção de dados para utilização em combinação com um equipamento de geração de imagens por ressonância magnética (irm), equipamento de geração de imagens, dispositivo de detecção de dados para utilização em combinação com um método de geração de imagens por ressonância magnética (irm), método de geração de imagens, programa de computador de detecção de dados, e programa de computador de geração de imagens |
| US9119550B2 (en) | 2012-03-30 | 2015-09-01 | Siemens Medical Solutions Usa, Inc. | Magnetic resonance and ultrasound parametric image fusion |
| US10561861B2 (en) | 2012-05-02 | 2020-02-18 | Viewray Technologies, Inc. | Videographic display of real-time medical treatment |
| EP2664359A1 (en) | 2012-05-14 | 2013-11-20 | Koninklijke Philips N.V. | Magnetic resonance guided therapy with interleaved scanning |
| US20130345545A1 (en) | 2012-06-21 | 2013-12-26 | Siemens Medical Solutions Usa, Inc. | Ultrasound Enhanced Magnetic Resonance Imaging |
| US8993898B2 (en) | 2012-06-26 | 2015-03-31 | ETS-Lindgren Inc. | Movable EMF shield, method for facilitating rapid imaging and treatment of patient |
| US9889318B2 (en) | 2012-10-26 | 2018-02-13 | Viewray Technologies, Inc. | Assessment and improvement of treatment using imaging of physiological responses to radiation therapy |
| EP2914172A4 (en) | 2012-11-02 | 2017-05-17 | The Regents Of The University Of California | Improved cardiac late gadolinium enhancement mri for patients with implanted cardiac devices |
| GB2507585B (en) | 2012-11-06 | 2015-04-22 | Siemens Plc | MRI magnet for radiation and particle therapy |
| GB2507792B (en) | 2012-11-12 | 2015-07-01 | Siemens Plc | Combined MRI and radiation therapy system |
| US10324148B2 (en) | 2013-02-06 | 2019-06-18 | Koninklijke Philips N.V. | Active compensation for field distorting components in a magnetic resonance imaging system with a gantry |
| US9404983B2 (en) | 2013-03-12 | 2016-08-02 | Viewray, Incorporated | Radio frequency transmit coil for magnetic resonance imaging system |
| US9675271B2 (en) | 2013-03-13 | 2017-06-13 | Viewray Technologies, Inc. | Systems and methods for radiotherapy with magnetic resonance imaging |
| US9289626B2 (en) | 2013-03-13 | 2016-03-22 | Viewray Incorporated | Systems and methods for improved radioisotopic dose calculation and delivery |
| US8952346B2 (en) | 2013-03-14 | 2015-02-10 | Viewray Incorporated | Systems and methods for isotopic source external beam radiotherapy |
| US9446263B2 (en) | 2013-03-15 | 2016-09-20 | Viewray Technologies, Inc. | Systems and methods for linear accelerator radiotherapy with magnetic resonance imaging |
| US10762167B2 (en) | 2013-09-27 | 2020-09-01 | Varian Medical Systems International Ag | Decision support tool for choosing treatment plans |
| EP3055706B1 (en) | 2013-10-08 | 2020-06-24 | Koninklijke Philips N.V. | Corrected multiple-slice magnetic resonance imaging |
| WO2015055473A1 (en) | 2013-10-17 | 2015-04-23 | Koninklijke Philips N.V. | Medical apparatus with a radiation therapy device and a radiation detection system |
| US9918639B2 (en) | 2013-11-07 | 2018-03-20 | Siemens Healthcard GmbH | Magnetic resonance imaging with asymmetric radial sampling and compressed-sensing reconstruction |
| US11045151B2 (en) | 2013-11-18 | 2021-06-29 | Varian Medical Systems, Inc. | Cone-beam computed tomography imaging devices, systems, and methods |
| CN110136176B (zh) | 2013-12-03 | 2022-12-09 | 优瑞技术公司 | 确定与医学图像的位移的系统 |
| US10737122B2 (en) | 2014-02-27 | 2020-08-11 | ETM Electromatic, Inc. | Self-shielded image guided radiation oncology system |
| US20170003363A1 (en) | 2014-03-14 | 2017-01-05 | Matthew S. Rosen | System and method for free radical imaging |
| US9931521B2 (en) | 2014-03-25 | 2018-04-03 | Varian Medical Systems, Inc. | Multi level multileaf collimator leaf tip shape effects and penumbra optimization |
| US10518108B2 (en) | 2014-05-09 | 2019-12-31 | Koninklijke Philips N.V. | Therapy system containing an MRI module and means for determining the position of an RF coil |
| US10850127B2 (en) | 2014-06-27 | 2020-12-01 | Koninklijke Philips N.V. | Charged particle beam therapy and magnetic resonance imaging |
| US10485496B2 (en) | 2014-08-25 | 2019-11-26 | Panacea Medical Technologies, Pvt., Ltd. | Radiotherapy apparatus with on-board stereotactic imaging system |
| US9950194B2 (en) | 2014-09-09 | 2018-04-24 | Mevion Medical Systems, Inc. | Patient positioning system |
| US11045108B2 (en) | 2014-11-26 | 2021-06-29 | Viewray Technologies, Inc. | Magnetic resonance imaging receive coil assembly |
| US9874620B2 (en) | 2015-02-05 | 2018-01-23 | Ohio State Innovation Foundation | Low field magnetic resonance imaging (MRI) scanner for cardiac imaging |
| JP6784697B2 (ja) | 2015-05-12 | 2020-11-11 | ハイパーファイン リサーチ,インコーポレイテッド | 高周波コイルの方法および装置 |
| KR20180033224A (ko) | 2015-07-22 | 2018-04-02 | 뷰레이 테크놀로지스 인크. | 방사선 측정을 위한 이온 챔버 |
| CN108367160A (zh) | 2015-11-24 | 2018-08-03 | 优瑞技术公司 | 辐射束准直系统和方法 |
| US10441816B2 (en) | 2015-12-31 | 2019-10-15 | Shanghai United Imaging Healthcare Co., Ltd. | Radiation therapy system |
| CN118750795A (zh) | 2016-03-02 | 2024-10-11 | 优瑞技术公司 | 放射疗法系统和相关的非暂时性计算机程序产品 |
| US9849306B2 (en) | 2016-03-21 | 2017-12-26 | Varian Medical Systems International Ag | Systems and methods for generating beam-specific planning target volume design outputs |
| WO2017223382A1 (en) | 2016-06-22 | 2017-12-28 | Viewray Technologies, Inc. | Magnetic resonance imaging at low field strength |
| US10307615B2 (en) | 2016-09-19 | 2019-06-04 | Varian Medical Systems International Ag | Optimization of radiation treatment plans for optimal treatment time in external-beam radiation treatments |
| US10143859B2 (en) | 2016-09-22 | 2018-12-04 | Varian Medical Systems International Ag | Controlling and shaping the dose distribution outside treatment targets in external-beam radiation treatments |
| US11221385B2 (en) | 2016-10-06 | 2022-01-11 | Koninklijke Philips N.V. | Impedance matching using multiple ports |
| EP3555649A1 (en) | 2016-12-15 | 2019-10-23 | Koninklijke Philips N.V. | Magnetic resonance antenna compatible with charged particle accelerator systems |
| US10485988B2 (en) | 2016-12-30 | 2019-11-26 | Varian Medical Systems International Ag | Interactive dose manipulation using prioritized constraints |
| US10166406B2 (en) | 2017-02-24 | 2019-01-01 | Varian Medical Systems International Ag | Radiation treatment planning and delivery using collision free regions |
| US10613171B2 (en) | 2017-03-14 | 2020-04-07 | Siemens Healthcare Gmbh | Multi-banded RF-pulse enhanced magnetization imaging |
| US10775460B2 (en) | 2017-06-28 | 2020-09-15 | Alberta Health Services | Image guided radiation therapy system |
| CN109420259A (zh) | 2017-08-24 | 2019-03-05 | 上海联影医疗科技有限公司 | 治疗系统和使用治疗系统的方法 |
| EP3456383B1 (en) | 2017-09-18 | 2021-03-24 | Medical Intelligence Medizintechnik GmbH | Motion management system for image-guided radiotherapy |
| US10661097B2 (en) | 2017-09-21 | 2020-05-26 | Varian Medical Systems, Inc. | VMAT treatment planning using multicriteria optimization and a progressive optimization scheme |
| EP3460500A1 (de) | 2017-09-26 | 2019-03-27 | Siemens Healthcare GmbH | Medizinisches bildgebungsgerät zur kombinierten magnetresonanzbildgebung und bestrahlung und verfahren zur bestimmung der bestückung von shim-einheiten |
| JP7127126B2 (ja) | 2017-12-06 | 2022-08-29 | ビューレイ・テクノロジーズ・インコーポレイテッド | 放射線治療のシステム、方法およびソフトウェア |
| US11209509B2 (en) | 2018-05-16 | 2021-12-28 | Viewray Technologies, Inc. | Resistive electromagnet systems and methods |
| CN111107900B (zh) | 2018-11-14 | 2022-03-04 | 上海联影医疗科技股份有限公司 | 放射治疗系统 |
| WO2020155137A1 (en) | 2019-02-02 | 2020-08-06 | Shanghai United Imaging Healthcare Co., Ltd. | Radiation therapy system and method |
-
2013
- 2013-10-25 US US14/064,053 patent/US9889318B2/en active Active
- 2013-10-25 EP EP13789652.8A patent/EP2911745B1/en active Active
- 2013-10-25 AU AU2013334064A patent/AU2013334064A1/en not_active Abandoned
- 2013-10-25 CN CN201380068528.6A patent/CN104902956B/zh active Active
- 2013-10-25 EP EP19190375.6A patent/EP3628370A1/en active Pending
- 2013-10-25 CA CA2888993A patent/CA2888993A1/en not_active Abandoned
- 2013-10-25 JP JP2015539874A patent/JP6382208B2/ja active Active
- 2013-10-25 CN CN201810196126.9A patent/CN108452443B/zh active Active
- 2013-10-25 KR KR1020157013230A patent/KR20150080527A/ko not_active Abandoned
- 2013-10-25 WO PCT/US2013/066963 patent/WO2014066853A1/en not_active Ceased
-
2017
- 2017-12-21 US US15/851,543 patent/US10835763B2/en active Active
-
2018
- 2018-05-01 AU AU2018203000A patent/AU2018203000B2/en not_active Expired - Fee Related
- 2018-08-01 JP JP2018145226A patent/JP6791915B2/ja active Active
- 2018-08-29 US US16/116,187 patent/US10821303B2/en active Active
- 2018-08-29 US US16/116,312 patent/US11040222B2/en active Active
-
2021
- 2021-06-11 US US17/346,109 patent/US12090343B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20190022414A1 (en) | 2019-01-24 |
| US20180133511A1 (en) | 2018-05-17 |
| US10821303B2 (en) | 2020-11-03 |
| EP2911745A1 (en) | 2015-09-02 |
| US20190022413A1 (en) | 2019-01-24 |
| WO2014066853A1 (en) | 2014-05-01 |
| KR20150080527A (ko) | 2015-07-09 |
| CN104902956B (zh) | 2018-04-03 |
| EP3628370A1 (en) | 2020-04-01 |
| US20140121495A1 (en) | 2014-05-01 |
| JP6791915B2 (ja) | 2020-11-25 |
| JP6382208B2 (ja) | 2018-08-29 |
| JP2018192281A (ja) | 2018-12-06 |
| US11040222B2 (en) | 2021-06-22 |
| US12090343B2 (en) | 2024-09-17 |
| EP2911745B1 (en) | 2019-08-07 |
| CN108452443A (zh) | 2018-08-28 |
| CN108452443B (zh) | 2021-05-18 |
| JP2015533581A (ja) | 2015-11-26 |
| AU2018203000A1 (en) | 2018-05-17 |
| AU2018203000B2 (en) | 2020-09-17 |
| US9889318B2 (en) | 2018-02-13 |
| US10835763B2 (en) | 2020-11-17 |
| CN104902956A (zh) | 2015-09-09 |
| US20210308488A1 (en) | 2021-10-07 |
| AU2013334064A1 (en) | 2015-05-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US12090343B2 (en) | Assessment and improvement of treatment using imaging of physiological responses to radiation therapy | |
| Salehi et al. | MRI of lymphedema | |
| Nout et al. | Hypertonic saline attenuates cord swelling and edema in experimental spinal cord injury: a study utilizing magnetic resonance imaging | |
| Zamboni et al. | Fixing the jugular flow reduces ventricle volume and improves brain perfusion | |
| Tran et al. | Quantitative ultrasound imaging of therapy response in bladder cancer in vivo | |
| Francescutti et al. | The benefit of intraperitoneal chemotherapy for the treatment of colorectal carcinomatosis | |
| Vellayappan et al. | Quantifying the changes in the tumour vascular micro-environment in spinal metastases treated with stereotactic body radiotherapy-a single arm prospective study | |
| HK1260136A1 (en) | System for assessment of treatment using imaging of physiological responses to radiation therapy | |
| Hartford et al. | Sensitizing brain metastases to stereotactic radiosurgery using hyperbaric oxygen: A proof-of-principle study | |
| Li et al. | Evaluation of Effect of Acupoint Sticking Therapy on Idiopathic Edema by Ultrasound Imaging Based on Deep Learning Algorithm | |
| Alghanimy | Investigating glymphatic system and AQP4 water channels with novel drugs and MRI techniques | |
| Loeser et al. | Therapy of lymphatic malformations or isolated lymphatic components in combined slow-flow malformations with bleomycin electrosclerotherapy (BEST) | |
| Ayasoufi et al. | SCIDOT-34. BRAIN INJURY SIGNALS SYSTEMIC IMMUNOSUPPRESSION THROUGH THYMIC INVOLUTION | |
| Prabhu et al. | Diagnostic Device for Kidney Health | |
| Brooks et al. | Longitudinal preclinical imaging characterization of drug delivery potential after radiotherapy in the healthy and leukemic bone marrow vascular microenvironment | |
| Jakubovic | MRI based physiological parameters are biomarkers of tumor and non tumor tissue response following radiation to brain metastases | |
| Ding et al. | DTI detection of microstructural changes induced by sleep deprivation | |
| Ding et al. | DTI investigation of short-term plasticity in amygdala and hippocampus induced by fear conditioning | |
| Wang et al. | Spatial proximity between subventricular zone and glioma in human patients | |
| Hou et al. | White matter development in preterm and term infants assessed by diffusion tensor imaging with tract-based spatial statistics | |
| Chan et al. | In vivo chromium-enhanced MRI of normal and injured retinas | |
| Kirwan et al. | Patient reported outcomes over 5 years following whole or partial breast radiotherapy: longitudinal analysis of the IMPORT LOW phase III randomised controlled trial | |
| Packard | Nuclear magnetic resonance imaging of tumor pathophysiology and angiogenesis | |
| Boos et al. | Practical approach to peripheral CE MRA: Resolution requirements. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20181022 |
|
| FZDE | Discontinued |
Effective date: 20211214 |