CA2879815A1 - Purification of virus like particles - Google Patents
Purification of virus like particles Download PDFInfo
- Publication number
- CA2879815A1 CA2879815A1 CA2879815A CA2879815A CA2879815A1 CA 2879815 A1 CA2879815 A1 CA 2879815A1 CA 2879815 A CA2879815 A CA 2879815A CA 2879815 A CA2879815 A CA 2879815A CA 2879815 A1 CA2879815 A1 CA 2879815A1
- Authority
- CA
- Canada
- Prior art keywords
- vlps
- solution
- norovirus
- filtrate
- subpopulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2770/16023—Virus like particles [VLP]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Landscapes
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- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US61/794,086 | 2013-03-15 | ||
| PCT/US2013/047249 WO2013192604A1 (en) | 2012-06-22 | 2013-06-24 | Purification of virus like particles |
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| ES2618885T3 (es) | 2006-09-29 | 2017-06-22 | Takeda Vaccines, Inc. | Formulaciones de vacuna para norovirus |
| KR20170001720A (ko) | 2007-03-14 | 2017-01-04 | 다케다 백신즈 인코포레이티드 | 바이러스 유사 입자 정제 |
| KR20100083150A (ko) | 2007-09-18 | 2010-07-21 | 리고사이트 파머슈티컬즈 인코퍼레이티드 | 노로바이러스에 대한 보호면역반응을 제공하는 방법 |
| HK1199202A1 (en) | 2011-07-11 | 2015-06-26 | 武田疫苗股份有限公司 | Parenteral norovirus vaccine formulations |
| JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
| EP3020808B1 (en) * | 2013-07-11 | 2019-09-11 | Takara Bio Inc. | Method for manufacturing adeno-associated virus |
| KR102474663B1 (ko) | 2013-10-03 | 2022-12-07 | 다케다 백신즈 인코포레이티드 | 세포주로부터 랍도바이러스를 탐지 및 제거하는 방법 |
| CN103981084B (zh) * | 2014-05-29 | 2015-11-18 | 黑龙江省科学院微生物研究所 | 水中病毒分离提取装置及水中札幌病毒的提取方法 |
| JP6616329B2 (ja) * | 2015-01-09 | 2019-12-04 | タカラバイオ株式会社 | 非エンベロープウイルス粒子の製造方法 |
| EP3245306A4 (en) | 2015-01-16 | 2018-09-05 | Takeda Vaccines, Inc. | Detection of particle-contained reverse transcriptase activity |
| CN105907729B (zh) * | 2015-05-05 | 2019-08-16 | 广东东阳光药业有限公司 | 一种制备人乳头瘤病毒l1蛋白类病毒样颗粒的方法 |
| CN107034198B (zh) * | 2015-07-15 | 2021-03-09 | 长春百克生物科技股份公司 | 一种嵌合诺如病毒p颗粒及其制备和应用 |
| WO2017040265A1 (en) | 2015-08-28 | 2017-03-09 | Nanotherapeutics, Inc. | Norovirus vaccine |
| CN105779399A (zh) * | 2016-03-28 | 2016-07-20 | 广西壮族自治区林业科学研究院 | 一种昆虫杆状病毒纯化方法 |
| GB201614050D0 (en) | 2016-08-17 | 2016-09-28 | Glaxosmithkline Ip Dev Ltd | Method for purifying viral vectors |
| CN109689092A (zh) * | 2016-09-01 | 2019-04-26 | 武田疫苗股份有限公司 | 用于产生用于疫苗生产的病毒的方法 |
| EP3420076B1 (en) | 2017-03-06 | 2024-02-21 | Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. | Methods of producing and characterizing virus vaccine and virus vaccine composition |
| EP4382183A3 (en) | 2017-03-06 | 2024-08-21 | Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. | Methods of producing and characterizing virus vaccine and virus vaccine composition |
| EP3752185A1 (en) | 2018-02-15 | 2020-12-23 | Icon Genetics GmbH | Immunogenic composition and vaccine for generating an immune response to norovirus |
| CN108676781A (zh) * | 2018-05-18 | 2018-10-19 | 山东信得动物疫苗有限公司 | 一种重组禽流感病毒的工业化纯化方法 |
| CN108776225A (zh) * | 2018-05-23 | 2018-11-09 | 中国农业科学院兰州兽医研究所 | 猪细小病毒VLPs抗体检测试剂盒及其制备方法、应用 |
| ES2953232T3 (es) | 2019-03-12 | 2023-11-08 | Icon Genetics Gmbh | Partículas similares a norovirus con estabilidad mejorada |
| CN115279896A (zh) | 2019-09-30 | 2022-11-01 | 比奥维拉迪维治疗股份有限公司 | 慢病毒载体配制品 |
| WO2022246323A1 (en) | 2021-05-21 | 2022-11-24 | Takeda Vaccines, Inc. | Solid composition, freeze-drying method and glass vial |
| JP2024524360A (ja) * | 2021-06-28 | 2024-07-05 | ブイエスティー エルエルシー ディービーエー メジン ラボ | サポウイルスワクチン |
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| EP2864478A4 (en) | 2015-12-02 |
| TW201406956A (zh) | 2014-02-16 |
| CN104583393A (zh) | 2015-04-29 |
| US11091519B2 (en) | 2021-08-17 |
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