MX366234B - Purificacion de particulas tipo virus. - Google Patents
Purificacion de particulas tipo virus.Info
- Publication number
- MX366234B MX366234B MX2014015842A MX2014015842A MX366234B MX 366234 B MX366234 B MX 366234B MX 2014015842 A MX2014015842 A MX 2014015842A MX 2014015842 A MX2014015842 A MX 2014015842A MX 366234 B MX366234 B MX 366234B
- Authority
- MX
- Mexico
- Prior art keywords
- particles
- virus
- purification
- methods
- vlps
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16051—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Analytical Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Métodos de purificación de partículas tipo virus (VLP), sustancialmente libres de contaminantes de proceso y agentes infecciosos. Los métodos incorporan, por ejemplo, un tratamiento a pH bajo durante la cosecha y/o inactivación con solvente y/o detergente durante la captura de las VLP.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261663218P | 2012-06-22 | 2012-06-22 | |
US201361794086P | 2013-03-15 | 2013-03-15 | |
PCT/US2013/047249 WO2013192604A1 (en) | 2012-06-22 | 2013-06-24 | Purification of virus like particles |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014015842A MX2014015842A (es) | 2015-09-07 |
MX366234B true MX366234B (es) | 2019-07-03 |
Family
ID=49769461
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014015842A MX366234B (es) | 2012-06-22 | 2013-06-24 | Purificacion de particulas tipo virus. |
Country Status (16)
Country | Link |
---|---|
US (3) | US10167320B2 (es) |
EP (1) | EP2864478B1 (es) |
JP (1) | JP6553509B2 (es) |
KR (1) | KR102110876B1 (es) |
CN (1) | CN104583393A (es) |
AR (1) | AR091538A1 (es) |
AU (1) | AU2013277959B2 (es) |
CA (1) | CA2879815A1 (es) |
HK (1) | HK1210210A1 (es) |
IN (1) | IN2015DN00089A (es) |
JO (1) | JOP20130186B1 (es) |
MX (1) | MX366234B (es) |
SG (2) | SG11201408459VA (es) |
TW (1) | TWI647310B (es) |
UY (1) | UY34875A (es) |
WO (1) | WO2013192604A1 (es) |
Families Citing this family (24)
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AU2007303608B2 (en) | 2006-09-29 | 2013-05-02 | Takeda Vaccines, Inc. | Norovirus vaccine formulations |
US8481693B2 (en) | 2007-03-14 | 2013-07-09 | Takeda Vaccines (Montana), Inc. | Virus like particle purification |
KR20100083150A (ko) | 2007-09-18 | 2010-07-21 | 리고사이트 파머슈티컬즈 인코퍼레이티드 | 노로바이러스에 대한 보호면역반응을 제공하는 방법 |
EA035442B1 (ru) | 2011-07-11 | 2020-06-17 | Такеда Вэксинс, Инк. | Композиции, содержащие буфер, вакцины, которые содержат композиции, содержащие буфер, и пути их применения |
JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
KR102069561B1 (ko) * | 2013-07-11 | 2020-01-23 | 다카라 바이오 가부시키가이샤 | 외피 비보유 바이러스의 제조 방법 |
EP3052631B1 (en) | 2013-10-03 | 2019-08-07 | Takeda Vaccines, Inc. | Methods of detection and removal of rhabdoviruses from cell lines |
CN103981084B (zh) * | 2014-05-29 | 2015-11-18 | 黑龙江省科学院微生物研究所 | 水中病毒分离提取装置及水中札幌病毒的提取方法 |
CN107109374B (zh) | 2015-01-09 | 2021-04-06 | 宝生物工程株式会社 | 用于生产无包膜病毒颗粒的方法 |
US10920288B2 (en) | 2015-01-16 | 2021-02-16 | Takeda Vaccines, Inc. | Detection of particle-contained reverse transcriptase activity |
CN105907729B (zh) * | 2015-05-05 | 2019-08-16 | 广东东阳光药业有限公司 | 一种制备人乳头瘤病毒l1蛋白类病毒样颗粒的方法 |
CN107034198B (zh) | 2015-07-15 | 2021-03-09 | 长春百克生物科技股份公司 | 一种嵌合诺如病毒p颗粒及其制备和应用 |
JP7033534B2 (ja) | 2015-08-28 | 2022-03-10 | オロジー バイオサーヴィシズ、インク. | ノロウイルスワクチン |
CN105779399A (zh) * | 2016-03-28 | 2016-07-20 | 广西壮族自治区林业科学研究院 | 一种昆虫杆状病毒纯化方法 |
GB201614050D0 (en) | 2016-08-17 | 2016-09-28 | Glaxosmithkline Ip Dev Ltd | Method for purifying viral vectors |
MX2019002495A (es) * | 2016-09-01 | 2020-02-17 | Takeda Vaccines Inc | Metodos para producir virus para la produccion de vacunas. |
EP4382183A2 (en) | 2017-03-06 | 2024-06-12 | Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. | Methods of producing and characterizing virus vaccine and virus vaccine composition |
EP3420076B1 (en) | 2017-03-06 | 2024-02-21 | Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. | Methods of producing and characterizing virus vaccine and virus vaccine composition |
US11633467B2 (en) | 2018-02-15 | 2023-04-25 | Icon Genetics Gmbh | Immunogenic composition and vaccine for generating an immune response to norovirus |
CN108676781A (zh) * | 2018-05-18 | 2018-10-19 | 山东信得动物疫苗有限公司 | 一种重组禽流感病毒的工业化纯化方法 |
CN108776225A (zh) * | 2018-05-23 | 2018-11-09 | 中国农业科学院兰州兽医研究所 | 猪细小病毒VLPs抗体检测试剂盒及其制备方法、应用 |
CA3133030A1 (en) | 2019-03-12 | 2020-09-17 | Icon Genetics Gmbh | Norovirus-like particles with improved stability |
JP2024519800A (ja) | 2021-05-21 | 2024-05-21 | タケダ ワクチン,インコーポレイテッド | 固体組成物、フリーズドライ方法およびガラスバイアル |
CN116789773B (zh) * | 2022-11-30 | 2024-02-20 | 华北制药金坦生物技术股份有限公司 | 一种胞内表达病毒样颗粒的粗纯方法 |
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JP2833106B2 (ja) | 1990-02-21 | 1998-12-09 | 株式会社島津製作所 | 液体クロマトグラフ |
WO1994026087A2 (en) | 1993-05-14 | 1994-11-24 | Connor Kim C O | Recombinant protein production and insect cell culture and process |
MXPA96005662A (es) | 1994-05-16 | 2004-08-19 | Merck & Co Inc | Vacunas de papilomavirus. |
AR004464A1 (es) | 1994-11-14 | 1998-12-16 | Merck Sharp & Dohme | Un metodo para producir una proteina de capside de papilomavirus |
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US7879338B2 (en) | 2003-07-21 | 2011-02-01 | Boyce Thompson Institute For Plant Research | Vectors and methods for immunization against norovirus using transgenic plants |
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US8277819B2 (en) | 2005-06-16 | 2012-10-02 | Children's Hospital Medical Center | Norovirus particle for use as an antiviral or vaccine |
EP1736538A1 (en) | 2005-06-21 | 2006-12-27 | Cytos Biotechnology AG | Process for the preparative purification of virus-like-particles (VLPs) |
WO2007081447A2 (en) | 2005-11-22 | 2007-07-19 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and sapovirus antigens |
PL1968630T3 (pl) | 2005-12-29 | 2018-08-31 | Boehringer Ingelheim Vetmedica, Inc. | Multiwalentne immunogenne kompozycje PCV2 |
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AU2007303608B2 (en) | 2006-09-29 | 2013-05-02 | Takeda Vaccines, Inc. | Norovirus vaccine formulations |
US8202967B2 (en) | 2006-10-27 | 2012-06-19 | Boehringer Ingelheim Vetmedica, Inc. | H5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use |
US8481693B2 (en) * | 2007-03-14 | 2013-07-09 | Takeda Vaccines (Montana), Inc. | Virus like particle purification |
EP2027875A1 (en) | 2007-08-23 | 2009-02-25 | Octapharma AG | A Process for Isolation and Purification of a Target Protein free of Prion Protein (PrPSC) |
KR20100083150A (ko) * | 2007-09-18 | 2010-07-21 | 리고사이트 파머슈티컬즈 인코퍼레이티드 | 노로바이러스에 대한 보호면역반응을 제공하는 방법 |
WO2009080781A1 (en) * | 2007-12-21 | 2009-07-02 | Cytos Biotechnology Ag | Process for clarifying cell homogenates |
AU2009279456B2 (en) | 2008-08-08 | 2015-02-05 | Takeda Vaccines, Inc. | Virus-like particles comprising composite capsid amino acid sequences for enhanced cross reactivity |
US20110262483A1 (en) | 2008-11-03 | 2011-10-27 | Ligocyte Pharmaceuticals, Inc. | Methods for isolating enveloped virus-based vlps free of infectious agents |
US8945895B2 (en) | 2009-07-31 | 2015-02-03 | Baxter International Inc. | Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof |
SG182636A1 (en) | 2010-01-21 | 2012-08-30 | Ligocyte Pharmaceuticals Inc | Targeted heterologous antigen presentation on calicivirus virus-like particles |
WO2012040216A1 (en) * | 2010-09-20 | 2012-03-29 | Bio-Rad Laboratories, Inc. | Dissociation of product-complexed contaminants in chromatography |
FI122520B (fi) | 2010-10-15 | 2012-03-15 | Vesna Blazevic | Noroviruksen kapsidi ja rotaviruksen VP6-proteiini käytettäväksi yhdistelmärokotteena |
CN102260651A (zh) * | 2011-06-24 | 2011-11-30 | 华中科技大学同济医学院附属协和医院 | 一种纯化病毒样颗粒蛋白的方法及其应用 |
JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
JP2015015931A (ja) | 2013-07-12 | 2015-01-29 | 株式会社Umnファーマ | ウイルス様粒子を含む培養物の製造方法 |
-
2013
- 2013-06-19 JO JOP/2013/0186A patent/JOP20130186B1/ar active
- 2013-06-21 TW TW102122276A patent/TWI647310B/zh active
- 2013-06-24 SG SG11201408459VA patent/SG11201408459VA/en unknown
- 2013-06-24 UY UY0001034875A patent/UY34875A/es active IP Right Grant
- 2013-06-24 KR KR1020157001131A patent/KR102110876B1/ko active IP Right Grant
- 2013-06-24 MX MX2014015842A patent/MX366234B/es active IP Right Grant
- 2013-06-24 SG SG10201610753YA patent/SG10201610753YA/en unknown
- 2013-06-24 EP EP13807804.3A patent/EP2864478B1/en active Active
- 2013-06-24 CA CA2879815A patent/CA2879815A1/en active Pending
- 2013-06-24 CN CN201380043618.XA patent/CN104583393A/zh active Pending
- 2013-06-24 US US13/925,449 patent/US10167320B2/en active Active
- 2013-06-24 WO PCT/US2013/047249 patent/WO2013192604A1/en active Application Filing
- 2013-06-24 AR ARP130102218 patent/AR091538A1/es active IP Right Grant
- 2013-06-24 JP JP2015518633A patent/JP6553509B2/ja active Active
- 2013-06-24 AU AU2013277959A patent/AU2013277959B2/en active Active
-
2015
- 2015-01-06 IN IN89DEN2015 patent/IN2015DN00089A/en unknown
- 2015-10-29 HK HK15110740.5A patent/HK1210210A1/xx unknown
-
2018
- 2018-11-27 US US16/201,073 patent/US11091519B2/en active Active
-
2021
- 2021-08-11 US US17/399,731 patent/US20220213147A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2015521628A (ja) | 2015-07-30 |
EP2864478A4 (en) | 2015-12-02 |
SG11201408459VA (en) | 2015-01-29 |
IN2015DN00089A (es) | 2015-05-29 |
US20140004145A1 (en) | 2014-01-02 |
JOP20130186B1 (ar) | 2021-08-17 |
WO2013192604A1 (en) | 2013-12-27 |
UY34875A (es) | 2013-12-31 |
CN114085273A (zh) | 2022-02-25 |
KR102110876B1 (ko) | 2020-05-14 |
CA2879815A1 (en) | 2013-12-27 |
KR20150051988A (ko) | 2015-05-13 |
AR091538A1 (es) | 2015-02-11 |
AU2013277959A1 (en) | 2015-01-22 |
TW201406956A (zh) | 2014-02-16 |
JP6553509B2 (ja) | 2019-07-31 |
US20190169236A1 (en) | 2019-06-06 |
CN104583393A (zh) | 2015-04-29 |
US10167320B2 (en) | 2019-01-01 |
TWI647310B (zh) | 2019-01-11 |
AU2013277959B2 (en) | 2019-05-16 |
MX2014015842A (es) | 2015-09-07 |
EP2864478A1 (en) | 2015-04-29 |
SG10201610753YA (en) | 2017-02-27 |
HK1210210A1 (en) | 2016-04-15 |
US20220213147A1 (en) | 2022-07-07 |
US11091519B2 (en) | 2021-08-17 |
EP2864478B1 (en) | 2020-12-09 |
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