CA2854330A1 - Overload and elute chromatography - Google Patents

Overload and elute chromatography Download PDF

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Publication number
CA2854330A1
CA2854330A1 CA2854330A CA2854330A CA2854330A1 CA 2854330 A1 CA2854330 A1 CA 2854330A1 CA 2854330 A CA2854330 A CA 2854330A CA 2854330 A CA2854330 A CA 2854330A CA 2854330 A1 CA2854330 A1 CA 2854330A1
Authority
CA
Canada
Prior art keywords
polypeptide
antibody
chromatography
conductivity
buffer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2854330A
Other languages
English (en)
French (fr)
Inventor
Deepa NADARAJAH
Amit Mehta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48192803&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2854330(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CA2854330A1 publication Critical patent/CA2854330A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/14—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3847—Multimodal interactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2854330A 2011-11-02 2012-11-02 Overload and elute chromatography Abandoned CA2854330A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161554898P 2011-11-02 2011-11-02
US61/554,898 2011-11-02
PCT/US2012/063242 WO2013067301A1 (en) 2011-11-02 2012-11-02 Overload and elute chromatography

Publications (1)

Publication Number Publication Date
CA2854330A1 true CA2854330A1 (en) 2013-05-10

Family

ID=48192803

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2854330A Abandoned CA2854330A1 (en) 2011-11-02 2012-11-02 Overload and elute chromatography

Country Status (25)

Country Link
US (3) US20140301977A1 (enExample)
EP (2) EP2773438B2 (enExample)
JP (4) JP6356607B2 (enExample)
KR (1) KR20140091721A (enExample)
CN (2) CN104023804B (enExample)
AU (1) AU2012323995B2 (enExample)
BR (1) BR112014010406A2 (enExample)
CA (1) CA2854330A1 (enExample)
DK (2) DK3257564T4 (enExample)
ES (2) ES2717536T5 (enExample)
FI (1) FI3257564T4 (enExample)
HR (1) HRP20190485T4 (enExample)
HU (2) HUE035685T2 (enExample)
IL (1) IL232146A0 (enExample)
LT (1) LT3257564T (enExample)
MX (1) MX2014005330A (enExample)
PL (2) PL2773438T5 (enExample)
PT (1) PT3257564T (enExample)
RS (1) RS58472B2 (enExample)
RU (1) RU2014121884A (enExample)
SG (1) SG11201402019TA (enExample)
SI (2) SI2773438T2 (enExample)
TR (1) TR201903707T4 (enExample)
WO (1) WO2013067301A1 (enExample)
ZA (1) ZA201402932B (enExample)

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JP2018184405A (ja) 2018-11-22
ZA201402932B (en) 2016-08-31
HUE035685T2 (en) 2018-05-28
DK2773438T3 (en) 2017-08-21
ES2637423T3 (es) 2017-10-13
JP2022033774A (ja) 2022-03-02
PL2773438T5 (pl) 2022-01-17
SI2773438T2 (sl) 2022-05-31
US20190023768A1 (en) 2019-01-24
AU2012323995B2 (en) 2016-06-09
SG11201402019TA (en) 2014-09-26
JP6356607B2 (ja) 2018-07-11
SI2773438T1 (sl) 2017-10-30
JP6979442B2 (ja) 2021-12-15
PL3257564T5 (pl) 2024-10-07
TR201903707T4 (tr) 2019-04-22
US20140301977A1 (en) 2014-10-09
DK2773438T4 (da) 2022-01-03
RS58472B1 (sr) 2019-04-30
JP2014532718A (ja) 2014-12-08
BR112014010406A2 (pt) 2017-04-25
ES2717536T3 (es) 2019-06-21
CN107163101B (zh) 2021-08-17
CN104023804B (zh) 2017-05-24
PL3257564T3 (pl) 2019-06-28
MX2014005330A (es) 2014-09-08
AU2012323995A1 (en) 2013-05-16
EP2773438A1 (en) 2014-09-10
KR20140091721A (ko) 2014-07-22
JP2020059718A (ja) 2020-04-16
US20210206836A1 (en) 2021-07-08
EP3257564B1 (en) 2019-01-23
SI3257564T1 (sl) 2019-04-30
JP7203928B2 (ja) 2023-01-13
EP3257564B2 (en) 2024-05-29
HK1201489A1 (zh) 2015-09-04
WO2013067301A1 (en) 2013-05-10
ES2637423T5 (es) 2022-03-17
EP3257564A1 (en) 2017-12-20
HRP20190485T1 (hr) 2019-04-19
EP2773438B1 (en) 2017-06-14
IL232146A0 (en) 2014-05-28
NZ624317A (en) 2016-06-24
FI3257564T4 (fi) 2024-08-30
RU2014121884A (ru) 2015-12-10
ES2717536T5 (en) 2025-02-04
PT3257564T (pt) 2019-03-22
CN107163101A (zh) 2017-09-15
EP3527274A1 (en) 2019-08-21
LT3257564T (lt) 2019-04-10
PL2773438T3 (pl) 2017-11-30
RS58472B2 (sr) 2024-10-31
HRP20190485T4 (hr) 2024-09-27
CN104023804A (zh) 2014-09-03
EP2773438A4 (en) 2015-06-03
DK3257564T3 (en) 2019-04-15
EP2773438B2 (en) 2021-10-20
HUE043755T2 (hu) 2019-09-30
SI3257564T2 (sl) 2024-10-30
DK3257564T4 (da) 2024-09-02

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