LT3257564T - Perkrovos ir eliuentinė chromatografija - Google Patents
Perkrovos ir eliuentinė chromatografijaInfo
- Publication number
- LT3257564T LT3257564T LTEP17157670.5T LT17157670T LT3257564T LT 3257564 T LT3257564 T LT 3257564T LT 17157670 T LT17157670 T LT 17157670T LT 3257564 T LT3257564 T LT 3257564T
- Authority
- LT
- Lithuania
- Prior art keywords
- overload
- elute chromatography
- elute
- chromatography
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/14—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
- B01D15/424—Elution mode
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
- B01D15/327—Reversed phase with hydrophobic interaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3847—Multimodal interactions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161554898P | 2011-11-02 | 2011-11-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
LT3257564T true LT3257564T (lt) | 2019-04-10 |
Family
ID=48192803
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP17157670.5T LT3257564T (lt) | 2011-11-02 | 2012-11-02 | Perkrovos ir eliuentinė chromatografija |
Country Status (25)
Country | Link |
---|---|
US (3) | US20140301977A1 (lt) |
EP (3) | EP2773438B2 (lt) |
JP (4) | JP6356607B2 (lt) |
KR (1) | KR20140091721A (lt) |
CN (2) | CN107163101B (lt) |
AU (1) | AU2012323995B2 (lt) |
BR (1) | BR112014010406A2 (lt) |
CA (1) | CA2854330A1 (lt) |
DK (2) | DK2773438T4 (lt) |
ES (2) | ES2637423T5 (lt) |
HK (1) | HK1201489A1 (lt) |
HR (1) | HRP20190485T1 (lt) |
HU (2) | HUE035685T2 (lt) |
IL (1) | IL232146A0 (lt) |
LT (1) | LT3257564T (lt) |
MX (1) | MX2014005330A (lt) |
PL (2) | PL2773438T5 (lt) |
PT (1) | PT3257564T (lt) |
RS (1) | RS58472B1 (lt) |
RU (1) | RU2014121884A (lt) |
SG (1) | SG11201402019TA (lt) |
SI (2) | SI2773438T2 (lt) |
TR (1) | TR201903707T4 (lt) |
WO (1) | WO2013067301A1 (lt) |
ZA (1) | ZA201402932B (lt) |
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WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
US9505833B2 (en) | 2012-04-20 | 2016-11-29 | Abbvie Inc. | Human antibodies that bind human TNF-alpha and methods of preparing the same |
US9334319B2 (en) | 2012-04-20 | 2016-05-10 | Abbvie Inc. | Low acidic species compositions |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
WO2013176754A1 (en) * | 2012-05-24 | 2013-11-28 | Abbvie Inc. | Novel purification of antibodies using hydrophobic interaction chromatography |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
CN105777862A (zh) * | 2012-10-24 | 2016-07-20 | 建新公司 | 使用mes和mops作为流动相改性剂从多峰树脂洗脱生物分子 |
US10023608B1 (en) | 2013-03-13 | 2018-07-17 | Amgen Inc. | Protein purification methods to remove impurities |
WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
EP3052640A2 (en) | 2013-10-04 | 2016-08-10 | AbbVie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
US20150139988A1 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
KR101891522B1 (ko) | 2013-12-12 | 2018-08-24 | 이엠디 밀리포어 코포레이션 | 아크릴아미드 함유 필터를 사용한 단백질 분리 |
US11219690B2 (en) * | 2013-12-13 | 2022-01-11 | Novo Nordisk Healthcare Ag | Method for thioether conjugation of proteins |
KR20150083689A (ko) * | 2014-01-10 | 2015-07-20 | 삼성전자주식회사 | 항 c-Met 항체 정제 방법 |
KR101921552B1 (ko) | 2014-03-10 | 2018-11-23 | 리히터 게데온 닐트. | 사전 세정 단계를 이용하는 면역글로불린 정제 |
CN106460027B (zh) * | 2014-03-24 | 2020-07-31 | 日东纺绩株式会社 | 使用阳离子性接枝聚合物的目标物分离浓缩方法 |
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TW201617360A (zh) * | 2014-06-25 | 2016-05-16 | 桂格 史考特 布蘭克 | 用於純化蛋白質之方法及試劑 |
CN104208719B (zh) * | 2014-09-24 | 2017-05-03 | 北京天广实生物技术股份有限公司 | 一种抗体偶联药物的阳离子交换层析纯化方法 |
EP3230299A1 (en) * | 2014-12-08 | 2017-10-18 | EMD Millipore Corporation | Mixed bed ion exchange adsorber |
SI3265557T1 (sl) * | 2015-03-06 | 2020-02-28 | F. Hoffmann-La Roche Ag | Ultraprečiščena DsbA in DsbC ter postopki njune izdelave in uporabe |
CN106290591B (zh) * | 2015-05-14 | 2019-07-26 | 上海医药工业研究院 | 一种庆大霉素C1a的检测方法 |
GB2539420B (en) * | 2015-06-16 | 2021-01-13 | Cytiva Sweden Ab | Determination of chromatography conditions |
EP3337818A1 (en) * | 2015-08-21 | 2018-06-27 | H. Hoffnabb-La Roche Ag | Affinity chromatography purification with low conductivity wash buffer |
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CN111351876A (zh) * | 2020-04-01 | 2020-06-30 | 上海中科新生命生物科技有限公司 | 一种抗体药中宿主细胞蛋白半绝对定量检测方法 |
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-
2012
- 2012-11-02 CA CA2854330A patent/CA2854330A1/en not_active Abandoned
- 2012-11-02 CN CN201710173196.8A patent/CN107163101B/zh active Active
- 2012-11-02 RU RU2014121884/10A patent/RU2014121884A/ru not_active Application Discontinuation
- 2012-11-02 MX MX2014005330A patent/MX2014005330A/es unknown
- 2012-11-02 DK DK12845437.8T patent/DK2773438T4/da active
- 2012-11-02 PL PL12845437T patent/PL2773438T5/pl unknown
- 2012-11-02 US US14/355,818 patent/US20140301977A1/en not_active Abandoned
- 2012-11-02 SI SI201231031T patent/SI2773438T2/sl unknown
- 2012-11-02 PL PL17157670T patent/PL3257564T3/pl unknown
- 2012-11-02 WO PCT/US2012/063242 patent/WO2013067301A1/en active Application Filing
- 2012-11-02 DK DK17157670.5T patent/DK3257564T3/en active
- 2012-11-02 HU HUE12845437A patent/HUE035685T2/en unknown
- 2012-11-02 TR TR2019/03707T patent/TR201903707T4/tr unknown
- 2012-11-02 SG SG11201402019TA patent/SG11201402019TA/en unknown
- 2012-11-02 EP EP12845437.8A patent/EP2773438B2/en active Active
- 2012-11-02 HU HUE17157670A patent/HUE043755T2/hu unknown
- 2012-11-02 BR BR112014010406A patent/BR112014010406A2/pt not_active Application Discontinuation
- 2012-11-02 ES ES12845437T patent/ES2637423T5/es active Active
- 2012-11-02 JP JP2014540118A patent/JP6356607B2/ja active Active
- 2012-11-02 ES ES17157670T patent/ES2717536T3/es active Active
- 2012-11-02 KR KR1020147014357A patent/KR20140091721A/ko not_active Application Discontinuation
- 2012-11-02 EP EP18206718.1A patent/EP3527274A1/en active Pending
- 2012-11-02 RS RS20190358A patent/RS58472B1/sr unknown
- 2012-11-02 EP EP17157670.5A patent/EP3257564B2/en active Active
- 2012-11-02 PT PT17157670T patent/PT3257564T/pt unknown
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- 2012-11-02 AU AU2012323995A patent/AU2012323995B2/en active Active
- 2012-11-02 CN CN201280065729.6A patent/CN104023804B/zh active Active
- 2012-11-02 SI SI201231562T patent/SI3257564T1/sl unknown
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2014
- 2014-04-22 IL IL232146A patent/IL232146A0/en unknown
- 2014-04-23 ZA ZA2014/02932A patent/ZA201402932B/en unknown
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2015
- 2015-03-02 HK HK15102085.5A patent/HK1201489A1/xx unknown
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2018
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2019
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2020
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2021
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