CA2778837C - Thin film processing apparatuses for adjustable volume accommodation - Google Patents

Thin film processing apparatuses for adjustable volume accommodation Download PDF

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Publication number
CA2778837C
CA2778837C CA2778837A CA2778837A CA2778837C CA 2778837 C CA2778837 C CA 2778837C CA 2778837 A CA2778837 A CA 2778837A CA 2778837 A CA2778837 A CA 2778837A CA 2778837 C CA2778837 C CA 2778837C
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CA
Canada
Prior art keywords
slide
liquid
curved portion
cover
platen assembly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2778837A
Other languages
English (en)
French (fr)
Other versions
CA2778837A1 (en
Inventor
Brian Howard Kram
Kevin David Marshall
Christine Tse
Timothy James Keller
Austin Micheil Ashby
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ventana Medical Systems Inc
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Ventana Medical Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Ventana Medical Systems Inc filed Critical Ventana Medical Systems Inc
Publication of CA2778837A1 publication Critical patent/CA2778837A1/en
Application granted granted Critical
Publication of CA2778837C publication Critical patent/CA2778837C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31Apparatus therefor
    • G01N1/312Apparatus therefor for samples mounted on planar substrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36Embedding or analogous mounting of samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CA2778837A 2009-11-13 2010-11-15 Thin film processing apparatuses for adjustable volume accommodation Expired - Fee Related CA2778837C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26126709P 2009-11-13 2009-11-13
US61/261,267 2009-11-13
PCT/US2010/056752 WO2011060387A1 (en) 2009-11-13 2010-11-15 Thin film processing apparatuses for adjustable volume accommodation

Publications (2)

Publication Number Publication Date
CA2778837A1 CA2778837A1 (en) 2011-05-19
CA2778837C true CA2778837C (en) 2016-01-19

Family

ID=43992102

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2778837A Expired - Fee Related CA2778837C (en) 2009-11-13 2010-11-15 Thin film processing apparatuses for adjustable volume accommodation

Country Status (11)

Country Link
US (2) US8911815B2 (enExample)
EP (1) EP2499500B1 (enExample)
JP (2) JP5611363B2 (enExample)
KR (1) KR101358549B1 (enExample)
CN (1) CN102687023B (enExample)
AU (1) AU2010320039B2 (enExample)
BR (1) BR112012011181A2 (enExample)
CA (1) CA2778837C (enExample)
IL (1) IL219086A (enExample)
IN (1) IN2012DN03245A (enExample)
WO (1) WO2011060387A1 (enExample)

Families Citing this family (120)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11249095B2 (en) 2002-04-15 2022-02-15 Ventana Medical Systems, Inc. Automated high volume slide processing system
US7468161B2 (en) 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
DE102009032703A1 (de) * 2009-07-09 2011-01-13 Mtu Aero Engines Gmbh Vorrichtung und Verfahren zum Anordnen eines Bauteils an einem Bauteilträger
WO2011053631A1 (en) 2009-10-28 2011-05-05 Alentic Microscience Inc. Microscopy imaging
US20140152801A1 (en) 2009-10-28 2014-06-05 Alentic Microscience Inc. Detecting and Using Light Representative of a Sample
US9075225B2 (en) 2009-10-28 2015-07-07 Alentic Microscience Inc. Microscopy imaging
US10746752B2 (en) 2009-11-13 2020-08-18 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
US10509216B2 (en) 2012-12-26 2019-12-17 Ventana Medical Systems, Inc. Specimen processing systems and methods for aligning slides
EP2499500B1 (en) 2009-11-13 2020-12-30 Ventana Medical Systems, Inc. Thin film processing apparatuses for adjustable volume accommodation
US9498791B2 (en) 2009-11-13 2016-11-22 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
WO2014102161A2 (en) * 2012-12-26 2014-07-03 Ventana Medical Systems, Inc. Specimen processing systems and methods for moderating evaporation
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
CA2851101C (en) 2010-10-06 2017-02-14 Biocare Medical, Llc Methods and systems for efficient processing of biological samples
US8454908B2 (en) * 2010-11-10 2013-06-04 Constitution Medical, Inc. Automated systems and methods for preparing biological specimens for examination
US9945763B1 (en) 2011-02-18 2018-04-17 Biocare Medical, Llc Methods and systems for immunohistochemistry heat retrieval of biological samples
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
US8932543B2 (en) * 2011-09-21 2015-01-13 Sakura Finetek U.S.A., Inc. Automated staining system and reaction chamber
WO2013071352A1 (en) 2011-11-16 2013-05-23 Leica Biosystems Melbourne Pty Ltd Cover member, method and treatment module for treating a biological sample on a substrate
US10036690B2 (en) * 2011-11-16 2018-07-31 Leica Biosystems Melbourne Pty Ltd Biological sample treatment apparatus
WO2013152330A1 (en) * 2012-04-06 2013-10-10 Ventana Medical Systems, Inc. Method and device for the homogeneous distribution of suspended cell components
ITRM20120436A1 (it) * 2012-09-13 2014-03-14 System Optimal Solution S R L Elemento per la realizzazione di repliche di indagini superficiali di materiali e metodo atto a realizzare tali indagini
US9869617B2 (en) 2012-10-08 2018-01-16 Ventana Medical Systems, Inc. Automated methods, kits, and systems for clarifying obfuscating pigments in histology samples
USRE50065E1 (en) 2012-10-17 2024-07-30 10X Genomics Sweden Ab Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
JP6117937B2 (ja) * 2012-12-26 2017-04-19 ベンタナ メディカル システムズ, インコーポレイテッド 標本処理システムおよびスライドガラスを均一に加熱する方法
DK2938995T3 (en) * 2012-12-26 2017-07-10 Ventana Med Syst Inc COUPLES AND AUTOMATED SAMPLING SYSTEMS WITH COUPLES
WO2014105739A1 (en) * 2012-12-26 2014-07-03 Ventana Medical Systems, Inc. Specimen processing systems and methods for preparing reagents
US9989448B2 (en) 2012-12-26 2018-06-05 Ventana Medical Systems, Inc. Specimen processing systems and methods for holding slides
CN104903697A (zh) * 2012-12-26 2015-09-09 文塔纳医疗系统公司 自动化标本处理系统以及对准和运输承载标本的显微镜载片的方法
US11274998B2 (en) 2012-12-26 2022-03-15 Ventana Medical Systems, Inc. Specimen processing systems and methods for holding slides
US10502666B2 (en) 2013-02-06 2019-12-10 Alentic Microscience Inc. Sample processing improvements for quantitative microscopy
USD728120S1 (en) 2013-03-15 2015-04-28 Ventana Medical Systems, Inc. Arcuate member for moving liquids along a microscope slide
EP2981801B1 (en) 2013-04-05 2020-01-01 Roche Diagnostics Hematology, Inc. Automated systems and methods for preparing biological specimens for examination
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
CN111500680B (zh) 2013-06-25 2024-04-16 普罗格诺西斯生物科学公司 检测样品中生物靶标的空间分布的方法和系统
CA2953620C (en) 2013-06-26 2020-08-25 Alentic Microscience Inc. Sample processing improvements for microscopy
EP3080580B1 (en) 2013-12-13 2021-05-05 Ventana Medical Systems, Inc. Staining reagents and other liquids for histological processing of biological specimens and associated technology
EP3080578B1 (en) 2013-12-13 2022-09-07 Ventana Medical Systems, Inc. Automated processing systems and methods of thermally processing microscope slides
WO2015086484A1 (en) 2013-12-13 2015-06-18 Ventana Medical Systems, Inc. Automated histological processing of biological specimens and associated technology
AU2015239720B2 (en) 2014-03-31 2019-07-11 Ventana Medical Systems, Inc. Automated specimen processing systems and multistep processing of microscope slides
AU2015279191B2 (en) * 2014-06-27 2018-07-26 F. Hoffmann-La Roche Ag Automated specimen processing systems and methods of detecting specimen-bearing microscope slides
CN104280280B (zh) * 2014-10-13 2016-12-07 赵烨梁 一种微漏进样法制备单分子样品的装置
EP3212761A1 (en) 2014-10-29 2017-09-06 Corning Incorporated Microwell design and fabrication for generation of cell culture aggregates
SG11201703493SA (en) 2014-10-29 2017-05-30 Corning Inc Cell culture insert
US10209166B2 (en) 2014-11-18 2019-02-19 Alfonso Heras System and method for processing biological specimens
JP2018512560A (ja) 2015-02-27 2018-05-17 ベンタナ メディカル システムズ, インコーポレイテッド アッセイ反応コントローラマガジン
EP4321627A3 (en) 2015-04-10 2024-04-17 10x Genomics Sweden AB Spatially distinguished, multiplex nucleic acid analysis of biological specimens
CN107615039A (zh) * 2015-05-26 2018-01-19 奥林巴斯株式会社 检查体染色装置和检查体染色方法
JP6688323B2 (ja) * 2015-07-02 2020-04-28 ベンタナ メディカル システムズ, インコーポレイテッド 流体制御要素を組み込んだ対向部および自動検体処理システム
CN105092865B (zh) * 2015-07-23 2017-07-18 爱威科技股份有限公司 试纸条淋样槽、淋样系统、干化分析仪及其淋样与清洗方法
KR101982332B1 (ko) 2015-08-10 2019-05-24 에센릭스 코프. 단계 간단화, 소량 샘플, 속도 가속화, 사용이 용이한 생물화학 측정장치 및 방법
US10605805B2 (en) 2015-09-14 2020-03-31 Essenlix Corporation Device and system for analyzing a sample, particularly blood, as well as methods of using the same
WO2017048881A1 (en) 2015-09-14 2017-03-23 Essenlix Corporation Device and system for collecting and analyzing vapor condensate, particularly exhaled breath condensate, as well as method of using the same
ITUB20155913A1 (it) * 2015-11-26 2017-05-26 Delcon S R L Apparecchiatura e metodo per la colorazione di vetrini
WO2017114750A1 (en) 2015-12-28 2017-07-06 Ventana Medical Systems, Inc. Opposables incorporating onboard reagents and automated specimen processing systems
JP6908624B2 (ja) 2016-04-27 2021-07-28 ベンタナ メディカル システムズ, インコーポレイテッド リアルタイム体積制御するためのシステムおよび方法
CA3048002A1 (en) 2016-12-21 2018-06-28 Essenlix Corporation Devices and methods for authenticating a sample and use of the same
DE102016225885B4 (de) * 2016-12-21 2023-12-21 Prime23 GmbH Vorrichtung und Verfahren zum Benetzen von biologischem Material
EP3579981A4 (en) 2017-02-07 2021-03-31 Essenlix Corporation COMPRESSED OPEN FLOW TEST AND USE
CN119000153A (zh) 2017-02-08 2024-11-22 上海宜晟生物科技有限公司 样品分析装置及其使用
US11927560B2 (en) 2017-02-08 2024-03-12 Essenlix Corporation Bio/chemical material extraction and assay
CA3052809A1 (en) 2017-02-08 2018-08-23 Essenlix Corporation Qmax assays and applications
CN110741240A (zh) 2017-02-08 2020-01-31 Essenlix公司 通过控制温度的分子操作和检测
CN118347819A (zh) * 2017-02-08 2024-07-16 爱威科技股份有限公司 一种样本染色装置
US11940382B2 (en) 2017-02-09 2024-03-26 Essenlix Corporation Assay with amplification
EP3662259A4 (en) 2017-02-09 2021-08-25 Essenlix Corporation COLORIMETRIC TESTS
JP7004732B2 (ja) 2017-02-09 2022-01-21 エッセンリックス コーポレーション 異なる間隔の高さを使用するアッセイ法
US12017218B2 (en) * 2017-02-15 2024-06-25 International Business Machines Corporation Hybrid microfluidics devices
EP3583423A4 (en) 2017-02-15 2021-03-31 Essenlix Corporation QUICK TEMPERATURE CHANGE DOSAGE
CN111448449B (zh) 2017-02-16 2024-08-27 上海宜晟生物科技有限公司 采用纹理化表面的测定方法及装置
US20210108996A1 (en) * 2017-03-31 2021-04-15 X-Zell Inc. Automatic slide staining and cooling systems
WO2018217953A1 (en) 2017-05-23 2018-11-29 Essenlix Corporation Rapid sample temperature changing for assaying
CN110637222A (zh) * 2017-05-26 2019-12-31 文塔纳医疗系统公司 非接触式、在载玻片上的流体混合
US12181472B2 (en) 2017-06-12 2024-12-31 Essenlix Corporation Homogeneous assay
WO2019014635A1 (en) 2017-07-14 2019-01-17 Corning Incorporated 3D CELL CULTURE CONTAINERS FOR MANUAL OR AUTOMATIC EXCHANGE
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
CN120668916A (zh) 2017-08-01 2025-09-19 上海宜晟生物科技有限公司 检查药物对微生物影响的装置和方法
US11280706B2 (en) 2017-08-01 2022-03-22 Essenlix Corporation Dilution calibration
US11243201B2 (en) 2017-08-01 2022-02-08 Essenlix Corporation Sample collection, holding and assaying
JP6539801B1 (ja) 2017-09-21 2019-07-03 浜松ホトニクス株式会社 試料支持体
WO2019075244A1 (en) 2017-10-11 2019-04-18 Essenlix Corporation CONTAINING A LIQUID SAMPLE
US11393561B2 (en) 2017-10-13 2022-07-19 Essenlix Corporation Devices and methods for authenticating a medical test and use of the same
US11221280B2 (en) * 2017-10-25 2022-01-11 Hitachi High-Tech Corporation Method of preparing biological tissue sample and method of observing biological tissue section sample
US11609224B2 (en) 2017-10-26 2023-03-21 Essenlix Corporation Devices and methods for white blood cell analyses
US11237113B2 (en) 2017-10-26 2022-02-01 Essenlix Corporation Rapid pH measurement
US10807095B2 (en) 2017-10-26 2020-10-20 Essenlix Corporation Making and tracking assay card
WO2019118652A1 (en) 2017-12-12 2019-06-20 Essenlix Corporation Sample manipulation and assay with rapid temperature change
WO2019118936A2 (en) 2017-12-14 2019-06-20 Essenlix Corporation Devices, systems, and methods for monitoring hair
WO2019122057A2 (en) 2017-12-24 2019-06-27 Ventana Medical Systems, Inc. Eosin staining techniques
EP3729048B1 (en) 2017-12-24 2023-08-30 Ventana Medical Systems, Inc. Phenol-free acid-fast staining composition and use thereof
US11156606B2 (en) 2018-01-11 2021-10-26 Essenlix Corporation Homogeneous assay (II)
WO2019137980A1 (en) 2018-01-11 2019-07-18 Ventana Medical Systems, Inc. Anti-fogging barcode reader
EP3649229B1 (en) * 2018-07-13 2021-08-25 Corning Incorporated Cell culture vessels with stabilizer devices
JP7171696B2 (ja) 2018-07-13 2022-11-15 コーニング インコーポレイテッド 相互接続されたウェルを有するマイクロプレートを備えた流体デバイス
JP7171695B2 (ja) 2018-07-13 2022-11-15 コーニング インコーポレイテッド 液体培地送達面を含む側壁を有するマイクロキャビティ皿
EP3824266B1 (en) 2018-07-16 2022-11-23 Ventana Medical Systems, Inc. Automated slide staining system and method for processing a specimen
WO2020016113A1 (en) 2018-07-16 2020-01-23 Ventana Medical Systems, Inc. Microscope slide processing systems, consumable stainer modules, and methods of using the same
US11885952B2 (en) 2018-07-30 2024-01-30 Essenlix Corporation Optics, device, and system for assaying and imaging
US20220033888A1 (en) 2018-12-10 2022-02-03 10X Genomics, Inc. Generating capture probes for spatial analysis
ES2988105T3 (es) * 2018-12-20 2024-11-19 Leica Biosystems Melbourne Pty Un módulo de salida de portaobjetos
MX392907B (es) * 2019-02-21 2025-03-20 Jesùs Raùl Beltran Ramìrez Aparato para el procesamiento inmunohistoquímico de múltiples muestras histológicas
US11712177B2 (en) 2019-08-12 2023-08-01 Essenlix Corporation Assay with textured surface
WO2021075000A1 (ja) * 2019-10-16 2021-04-22 株式会社日立ハイテク 貼付方法、観察方法、貼付条件推定システム、切片作製装置、顕微鏡用スライドの製造方法、顕微鏡用スライド及びサーバ
US12157124B2 (en) 2019-11-06 2024-12-03 10X Genomics, Inc. Imaging system hardware
US11768175B1 (en) 2020-03-04 2023-09-26 10X Genomics, Inc. Electrophoretic methods for spatial analysis
US11846643B2 (en) * 2020-03-27 2023-12-19 Alpha Technologies Services Llc Test sample handling system with rotary carousel
DE102020204670A1 (de) * 2020-04-14 2021-10-14 Prime23 GmbH Vorrichtung und Verfahren zum Benetzen von biologischen Material mit wenigstens einer Flüssigkeit sowie eine Halteeinrichtung
US12031177B1 (en) 2020-06-04 2024-07-09 10X Genomics, Inc. Methods of enhancing spatial resolution of transcripts
ES2981265T3 (es) 2020-06-08 2024-10-08 10X Genomics Inc Métodos para determinar un margen quirúrgico y métodos de uso del mismo
AU2021288090A1 (en) * 2020-06-10 2023-01-19 10X Genomics, Inc. Fluid delivery methods
ES2993269T3 (en) 2020-09-18 2024-12-26 10X Genomics Inc Sample handling apparatus and image registration methods
AU2021409136A1 (en) 2020-12-21 2023-06-29 10X Genomics, Inc. Methods, compositions, and systems for capturing probes and/or barcodes
US20240160000A1 (en) * 2021-05-27 2024-05-16 Scopio Labs Ltd. Coverslipping method
EP4347879B1 (en) 2021-06-03 2025-02-19 10X Genomics, Inc. Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis
WO2023091750A1 (en) * 2021-11-19 2023-05-25 Cornell University Surface-patterned, omniphobic tiles (spots), fabrication, loading, and use thereof
WO2023102118A2 (en) 2021-12-01 2023-06-08 10X Genomics, Inc. Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis
WO2023122033A1 (en) 2021-12-20 2023-06-29 10X Genomics, Inc. Self-test for pathology/histology slide imaging device
CN120344649A (zh) * 2022-11-15 2025-07-18 沃特世科技公司 压制和混合的薄膜酶反应器及其制备方法
WO2024237277A1 (ja) * 2023-05-18 2024-11-21 株式会社Screenホールディングス 標本封入方法および標本封入装置
WO2025024557A1 (en) * 2023-07-25 2025-01-30 Ruby Robotics Inc Staining methods for automated systems

Family Cites Families (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3551023A (en) 1969-01-17 1970-12-29 Ibm Pathology specimen processing method and article
US3556633A (en) 1969-01-17 1971-01-19 Winifred Liu Mutschmann Specimen carrying slide with runoff trough
US3672745A (en) 1970-06-29 1972-06-27 Propper Mfg Co Inc Bevelled edge microscope slide
GB1457137A (en) 1973-08-16 1976-12-01 Wyeth John & Brother Ltd Apparatus for handling coverslips
FR2263502B1 (enExample) * 1974-03-06 1976-12-10 Ass Ctre Transfusion San
US3961346A (en) 1975-01-30 1976-06-01 Miles Laboratories, Inc. Liquid inspection slide
US4023949A (en) 1975-08-04 1977-05-17 Schlom Leslie A Evaporative refrigeration system
SE403940B (sv) 1976-02-26 1978-09-11 Cytologiska Centrallab Sett och anordning for maskinell applicering av teckplattor pa med preparat for mikroskopisk undersokning forsedda objektglas
US4203797A (en) 1977-05-09 1980-05-20 Cytologiska Centrallaboratoriet Ab Method of and apparatus for applying cover-slips to slides carrying specimens for microscopic examination
US4146414A (en) 1977-05-09 1979-03-27 Cytologiska Centrallaboratoriet Ab Method for applying cover-slips to slides carrying specimens for microscopic examination
US4418527A (en) 1980-04-21 1983-12-06 Schlom Leslie A Precooler for gas turbines
US4359013A (en) 1980-09-08 1982-11-16 Prevo Donald L Device for spreading monolayered films
US4392450A (en) 1981-02-12 1983-07-12 Prevo Donald L Device for spreading monolayered films
US4336765A (en) 1981-06-12 1982-06-29 Coughlin Vincent D Vacuum work piece holder
US4428793A (en) 1981-08-25 1984-01-31 Meisei Electric Co., Ltd. Preparation method for a microscopic specimen and a device therefor
JPS5840519A (ja) * 1981-09-03 1983-03-09 Meisei Electric Co Ltd 顕微鏡用標本の封入方法
JPS58140457U (ja) * 1982-03-18 1983-09-21 明星電気株式会社 顕微鏡標本作成装置の試料固定機構
US4597982A (en) 1982-03-18 1986-07-01 Delameter William D Method for processing flexible sheets
US4731335A (en) 1985-09-13 1988-03-15 Fisher Scientific Company Method for treating thin samples on a surface employing capillary flow
US5023187A (en) 1985-09-13 1991-06-11 Fisher Scientific Company Method and device for accelerated treatment of thin sample on surface
US4790640A (en) 1985-10-11 1988-12-13 Nason Frederic L Laboratory slide
US5002736A (en) 1987-03-31 1991-03-26 Fisher Scientific Co. Microscope slide and slide assembly
US4849340A (en) 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
GB8722902D0 (en) 1987-09-30 1987-11-04 Shandon Southern Prod Tissue &c processing
US4911782A (en) 1988-03-28 1990-03-27 Cyto-Fluidics, Inc. Method for forming a miniaturized biological assembly
US5503803A (en) 1988-03-28 1996-04-02 Conception Technologies, Inc. Miniaturized biological assembly
US5188963A (en) 1989-11-17 1993-02-23 Gene Tec Corporation Device for processing biological specimens for analysis of nucleic acids
US5281516A (en) 1988-08-02 1994-01-25 Gene Tec Corporation Temperature control apparatus and method
US5346672A (en) 1989-11-17 1994-09-13 Gene Tec Corporation Devices for containing biological specimens for thermal processing
US5595707A (en) * 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
ATE155592T1 (de) 1990-03-30 1997-08-15 Neuromedical Systems Inc Automatisches zellenklassifikationssystem und verfahren
US5075079A (en) 1990-05-21 1991-12-24 Technicon Instruments Corporation Slide analysis system
US5273905A (en) 1991-02-22 1993-12-28 Amoco Corporation Processing of slide mounted material
US5189751A (en) 1991-03-21 1993-03-02 Gemtech, Inc. Vibrating toothbrush using a magnetic driver
JP3320444B2 (ja) 1992-04-06 2002-09-03 株式会社千代田製作所 染色装置用ノズル洗浄装置
US5256241A (en) 1992-08-28 1993-10-26 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method for controlling protein crystallization
NO179729C (no) 1992-12-11 1996-12-04 Oeystein H Ljungmann Apparat for automatisk påklebing av dekkglass på objektglass
US5364790A (en) 1993-02-16 1994-11-15 The Perkin-Elmer Corporation In situ PCR amplification system
JP3292765B2 (ja) * 1993-07-30 2002-06-17 株式会社千代田製作所 顕微鏡標本の染色方法とその装置
AUPM352194A0 (en) 1994-01-25 1994-02-17 Australian Biomedical Corporation Limited Instrument for automatically applying coverslips and method
AUPN038995A0 (en) 1995-01-05 1995-01-27 Australian Biomedical Corporation Limited Method and apparatus for human or animal cell sample treatment
GB9506312D0 (en) 1995-03-28 1995-05-17 Medical Res Council Improvements in or relating to sample processing
AUPN357495A0 (en) 1995-06-15 1995-07-06 Australian Biomedical Corporation Limited Coverslip pick-up and laydown apparatus
JPH0943118A (ja) * 1995-07-31 1997-02-14 Aloka Co Ltd 生物組織の処理装置
GB9518129D0 (en) 1995-09-06 1995-11-08 Zynocyte Ltd Stain and capillary slide
US5650332A (en) 1995-11-14 1997-07-22 Coulter International Corp. Method for the preparation of microscope slides
DE69733745T2 (de) * 1996-01-16 2006-04-20 World Properties, Inc., Lincolnwood Mit walze beschichtetes elektrolumineszentes paneel
AUPN762196A0 (en) 1996-01-17 1996-02-08 Australian Biomedical Corporation Limited Specimen preparation apparatus
AUPN923596A0 (en) * 1996-04-12 1996-05-09 Australian Biomedical Corporation Limited Method and apparatus for treatment of human or animal cell samples
WO1997042496A1 (en) 1996-05-06 1997-11-13 Helena Laboratories Corporation A system for the application of samples on a substrate__________
JP3419430B2 (ja) 1996-08-21 2003-06-23 日本電子株式会社 生化学自動分析装置における試薬注入攪拌装置
JP3753526B2 (ja) 1996-12-18 2006-03-08 サクラ精機株式会社 顕微鏡標本のカバーガラス貼着方法と装置
US6703247B1 (en) 1996-12-23 2004-03-09 American Registry Of Pathology Apparatus and methods for efficient processing of biological samples on slides
AUPO439496A0 (en) * 1996-12-24 1997-01-23 Australian Biomedical Corporation Pty. Ltd. Smearer mechanism
JPH10197424A (ja) * 1997-01-14 1998-07-31 Chiyoda Manufacturing Co Ltd 顕微鏡標本のカバーガラス取付け方法及び装置
US6489171B1 (en) 1997-04-18 2002-12-03 Cell Marque Corporation Chemical dispensing system and method
US6567214B2 (en) 1997-09-04 2003-05-20 Andrew E. Lorincz Microscope slide having culture media and method for use
US5812312A (en) 1997-09-04 1998-09-22 Lorincz; Andrew Endre Microscope slide
US6239906B1 (en) 1997-09-04 2001-05-29 Andrew E. Lorincz Flexible microscope slide
US6486947B2 (en) 1998-07-22 2002-11-26 Ljl Biosystems, Inc. Devices and methods for sample analysis
CA2720326C (en) 1997-12-23 2014-11-25 Dako Denmark A/S Cartridge device for processing a sample mounted on a surface of a support member
US6083759A (en) 1997-12-30 2000-07-04 University Of Hawaii Blood smearing cassette
US6037168A (en) 1997-12-31 2000-03-14 Cytonix Corporation Microbiological assembly comprising resealable closure means
JPH11202215A (ja) * 1998-01-09 1999-07-30 Chiyoda Mfg Co Ltd 顕微鏡標本のカバーガラス貼着方法と装置
US6589650B1 (en) 2000-08-07 2003-07-08 3M Innovative Properties Company Microscope cover slip materials
CN100403008C (zh) * 1998-02-27 2008-07-16 文塔纳医疗系统公司 对组织样品进行处理的方法及装置
US20030211630A1 (en) 1998-02-27 2003-11-13 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
AU762808B2 (en) 1998-03-24 2003-07-03 Biogenex Laboratories Automated staining apparatus
US6358475B1 (en) 1998-05-27 2002-03-19 Becton, Dickinson And Company Device for preparing thin liquid for microscopic analysis
US6180314B1 (en) * 1998-05-27 2001-01-30 Becton, Dickinson And Company Method for preparing thin liquid samples for microscopic analysis
NO986025D0 (no) * 1998-12-21 1998-12-21 Torstein Ljungmann Maskin for automatisk pÕklebing av dekkglass pÕ objektglass
US6544798B1 (en) 1999-02-26 2003-04-08 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US6568447B1 (en) 1999-05-11 2003-05-27 Kabushiki Kaisha Tiyoda Seisakusho Cover glass adhering device
US6474386B2 (en) 1999-08-25 2002-11-05 Kabushiki Kaisha Tiyoda Seisakusho Cover glass adhering device
US6403931B1 (en) 1999-10-07 2002-06-11 Ventana Medical Systems, Inc. Slide heater calibrator and temperature converter apparatus and method
WO2001033190A2 (en) 1999-11-04 2001-05-10 Arcturus Engineering, Inc. Automated laser capture microdissection
USD445909S1 (en) 1999-11-11 2001-07-31 Hemocue Ab Cuvette
NO310385B1 (no) 1999-11-17 2001-06-25 Torstein Ljungmann Anordning for automatisk påklebing av dekkglass på objektglass
ES2312416T3 (es) 2000-02-23 2009-03-01 Schlom, Leslie Un intercambiador de calor de enfriammiento y de preenfriamiento para el acondicionamiento del aire de admision de un turbina.
USD464141S1 (en) 2000-10-17 2002-10-08 Acon Laboratories, Inc. Test device platform
US6717657B2 (en) 2001-01-02 2004-04-06 Becton, Dickinson And Company Apparatus for measuring the volume of individual red blood cells
US6544793B2 (en) 2001-04-27 2003-04-08 Becton, Dickinson And Company Method for calibrating a sample analyzer
US6485918B1 (en) * 2001-07-02 2002-11-26 Packard Bioscience Corporation Method and apparatus for incubation of a liquid reagent and target spots on a microarray substrate
DE10144048B4 (de) 2001-09-07 2012-09-20 Leica Mikrosysteme Gmbh Vorrichtung und Verfahren zum Handhaben von Deckgläsern für Objektträger
US7425306B1 (en) 2001-09-11 2008-09-16 Ventana Medical Systems, Inc. Slide heater
US20030087292A1 (en) 2001-10-04 2003-05-08 Shiping Chen Methods and systems for promoting interactions between probes and target molecules in fluid in microarrays
US7468161B2 (en) * 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
AU2003228709B2 (en) 2002-04-26 2006-12-21 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having fixed slide platforms
DE60322043D1 (de) 2002-04-26 2008-08-21 Ventana Med Syst Inc Verfahren und vorrichtung zum automatisierten aufnehmen und ablegen von deckgläsern
US7919308B2 (en) 2002-06-14 2011-04-05 Agilent Technologies, Inc. Form in place gaskets for assays
AU2003240295A1 (en) 2002-06-20 2004-01-06 Vision Biosystems Limited Biological reaction apparatus with draining mechanism
AUPS309002A0 (en) * 2002-06-20 2002-07-11 Vision Biosystems Limited A covertile for a substrate
US7063758B2 (en) * 2002-07-29 2006-06-20 Three Bond Co., Ltd. Laminating apparatus and laminating method
US7452712B2 (en) 2002-07-30 2008-11-18 Applied Biosystems Inc. Sample block apparatus and method of maintaining a microcard on a sample block
USD495806S1 (en) 2002-08-08 2004-09-07 Exiqon A/S Slide for use in chemical or biochemical procedures
US7186383B2 (en) 2002-09-27 2007-03-06 Ast Management Inc. Miniaturized fluid delivery and analysis system
US20040082058A1 (en) 2002-10-29 2004-04-29 Arthur Schleifer Array hybridization apparatus and method for making uniform sample volumes
US7850912B2 (en) 2003-05-14 2010-12-14 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
WO2004083824A1 (en) 2003-03-20 2004-09-30 Dakocytomation Denmark A/S System for establishing a sample cover on a substrate
US7468160B2 (en) 2003-12-05 2008-12-23 Agilent Technologies, Inc. Devices and methods for performing array based assays
US7615371B2 (en) 2003-12-23 2009-11-10 Ventana Medical Systems, Inc. Method and apparatus for treating a biological sample with a liquid reagent
EP1771730B1 (en) 2004-07-23 2014-08-20 Ventana Medical Systems, Inc. Method and apparatus for applying fluids to a biological sample
DE102004037848B4 (de) 2004-08-04 2007-03-29 Advalytix Ag Probenträgerwaschbehälter, Probenträgerwaschstation, System zum Waschen von Probenträgern und Verfahren zum Waschen von Probenträgern
US7481980B2 (en) 2004-09-08 2009-01-27 Intavis Bioanalytical Instruments Ag Device for staining and hybridization reactions
US7300804B2 (en) 2004-11-15 2007-11-27 Beckman Coulter, Inc. Method and apparatus for controlling the uniform smearing of a biological liquid over a substrate
JP2008538611A (ja) * 2005-04-21 2008-10-30 セレラス ダイアグノスティクス, インコーポレイテッド 自動高速免疫組織化学のための平行処理の流体方法および装置
JP4607703B2 (ja) * 2005-08-22 2011-01-05 東芝機械株式会社 薄切片標本作製方法
US20100031757A1 (en) 2006-04-26 2010-02-11 Quantifoil Instruments Gmbh sample handling device for and a method of handling a sample
USD569990S1 (en) 2006-09-28 2008-05-27 Millennium Sciences Microscope slide assembly
US20110217731A1 (en) 2008-06-16 2011-09-08 Mayo Foundation For Medical Education And Research Pathology sample processing workstation
EP2374430B1 (en) 2008-12-08 2016-10-12 Sunstar Inc. Linear actuator
WO2010074917A1 (en) 2008-12-24 2010-07-01 Ventana Medical Systems, Inc. Microscope-slide dryer
US9498791B2 (en) 2009-11-13 2016-11-22 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
EP2499500B1 (en) 2009-11-13 2020-12-30 Ventana Medical Systems, Inc. Thin film processing apparatuses for adjustable volume accommodation
WO2011139978A1 (en) 2010-05-04 2011-11-10 Ventana Medical Systems, Inc. Moving meniscus rinsing and mixing in cell staining
USD645971S1 (en) 2010-05-11 2011-09-27 Claros Diagnostics, Inc. Sample cassette
US20110305842A1 (en) 2010-06-11 2011-12-15 Ventana Medical Systems, Inc. Floatable opposables for applying fluids to process biological samples
EP2819775A1 (en) 2012-03-01 2015-01-07 Victorious Medical Systems ApS Method and system for distributing and agitating an amount of liquid over a microscope slide
DK2938995T3 (en) 2012-12-26 2017-07-10 Ventana Med Syst Inc COUPLES AND AUTOMATED SAMPLING SYSTEMS WITH COUPLES
WO2014105739A1 (en) 2012-12-26 2014-07-03 Ventana Medical Systems, Inc. Specimen processing systems and methods for preparing reagents
USD728120S1 (en) 2013-03-15 2015-04-28 Ventana Medical Systems, Inc. Arcuate member for moving liquids along a microscope slide

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