JP5611363B2 - 調整可能な体積を収容する薄膜処理装置 - Google Patents

調整可能な体積を収容する薄膜処理装置 Download PDF

Info

Publication number
JP5611363B2
JP5611363B2 JP2012539061A JP2012539061A JP5611363B2 JP 5611363 B2 JP5611363 B2 JP 5611363B2 JP 2012539061 A JP2012539061 A JP 2012539061A JP 2012539061 A JP2012539061 A JP 2012539061A JP 5611363 B2 JP5611363 B2 JP 5611363B2
Authority
JP
Japan
Prior art keywords
slide
liquid
gap
cover
curved portion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2012539061A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013511048A (ja
Inventor
クラム，ブライアン・ハワード
マーシャル，ケヴィン・デーヴィッド
チェ，クリスティン
ケラー，ティモシー・ジェームズ
アシュビー，オースティン・マイケル
Original Assignee
ベンタナ メディカル システムズ， インコーポレイテッド
ベンタナ メディカル システムズ， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ベンタナ メディカル システムズ， インコーポレイテッド, ベンタナ メディカル システムズ， インコーポレイテッド filed Critical ベンタナ メディカル システムズ， インコーポレイテッド
Publication of JP2013511048A publication Critical patent/JP2013511048A/ja
Application granted granted Critical
Publication of JP5611363B2 publication Critical patent/JP5611363B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
JP2012539061A 2009-11-13 2010-11-15 調整可能な体積を収容する薄膜処理装置 Expired - Fee Related JP5611363B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26126709P 2009-11-13 2009-11-13
US61/261,267 2009-11-13
PCT/US2010/056752 WO2011060387A1 (en) 2009-11-13 2010-11-15 Thin film processing apparatuses for adjustable volume accommodation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014177783A Division JP5923145B2 (ja) 2009-11-13 2014-09-02 調整可能な体積を収容する薄膜処理装置

Publications (2)

Publication Number Publication Date
JP2013511048A JP2013511048A (ja) 2013-03-28
JP5611363B2 true JP5611363B2 (ja) 2014-10-22

Family

ID=43992102

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012539061A Expired - Fee Related JP5611363B2 (ja) 2009-11-13 2010-11-15 調整可能な体積を収容する薄膜処理装置
JP2014177783A Expired - Fee Related JP5923145B2 (ja) 2009-11-13 2014-09-02 調整可能な体積を収容する薄膜処理装置

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014177783A Expired - Fee Related JP5923145B2 (ja) 2009-11-13 2014-09-02 調整可能な体積を収容する薄膜処理装置

Country Status (11)

Country Link
US (2) US8911815B2 (enExample)
EP (1) EP2499500B1 (enExample)
JP (2) JP5611363B2 (enExample)
KR (1) KR101358549B1 (enExample)
CN (1) CN102687023B (enExample)
AU (1) AU2010320039B2 (enExample)
BR (1) BR112012011181A2 (enExample)
CA (1) CA2778837C (enExample)
IL (1) IL219086A (enExample)
IN (1) IN2012DN03245A (enExample)
WO (1) WO2011060387A1 (enExample)

Families Citing this family (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7468161B2 (en) 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
US11249095B2 (en) 2002-04-15 2022-02-15 Ventana Medical Systems, Inc. Automated high volume slide processing system
DE102009032703A1 (de) * 2009-07-09 2011-01-13 Mtu Aero Engines Gmbh Vorrichtung und Verfahren zum Anordnen eines Bauteils an einem Bauteilträger
US20140152801A1 (en) 2009-10-28 2014-06-05 Alentic Microscience Inc. Detecting and Using Light Representative of a Sample
US9075225B2 (en) 2009-10-28 2015-07-07 Alentic Microscience Inc. Microscopy imaging
WO2011053631A1 (en) 2009-10-28 2011-05-05 Alentic Microscience Inc. Microscopy imaging
US10509216B2 (en) 2012-12-26 2019-12-17 Ventana Medical Systems, Inc. Specimen processing systems and methods for aligning slides
EP2499500B1 (en) 2009-11-13 2020-12-30 Ventana Medical Systems, Inc. Thin film processing apparatuses for adjustable volume accommodation
US10746752B2 (en) 2009-11-13 2020-08-18 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
US9498791B2 (en) 2009-11-13 2016-11-22 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
CA2851101C (en) 2010-10-06 2017-02-14 Biocare Medical, Llc Methods and systems for efficient processing of biological samples
CN107478484B (zh) 2010-11-10 2021-03-30 罗氏血液诊断股份有限公司 制备用于检查的生物标本的自动化系统及方法
US9945763B1 (en) 2011-02-18 2018-04-17 Biocare Medical, Llc Methods and systems for immunohistochemistry heat retrieval of biological samples
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
US8932543B2 (en) * 2011-09-21 2015-01-13 Sakura Finetek U.S.A., Inc. Automated staining system and reaction chamber
AU2012339621B2 (en) * 2011-11-16 2016-02-18 Leica Biosystems Melbourne Pty Ltd Biological sample treatment apparatus
WO2013071352A1 (en) * 2011-11-16 2013-05-23 Leica Biosystems Melbourne Pty Ltd Cover member, method and treatment module for treating a biological sample on a substrate
WO2013152330A1 (en) * 2012-04-06 2013-10-10 Ventana Medical Systems, Inc. Method and device for the homogeneous distribution of suspended cell components
ITRM20120436A1 (it) * 2012-09-13 2014-03-14 System Optimal Solution S R L Elemento per la realizzazione di repliche di indagini superficiali di materiali e metodo atto a realizzare tali indagini
AU2013329655B2 (en) 2012-10-08 2017-01-12 Ventana Medical Systems, Inc. Methods, kits, and systems for clarifying pigmented samples
EP3901280B1 (en) 2012-10-17 2025-03-12 10x Genomics Sweden AB Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
SG11201505019WA (en) * 2012-12-26 2015-07-30 Ventana Med Syst Inc Specimen processing systems and methods for holding slides
ES2637775T3 (es) * 2012-12-26 2017-10-17 Ventana Medical Systems, Inc. Sistemas de procesamiento de especímenes y métodos para la preparación de reactivos
HK1213990A1 (zh) * 2012-12-26 2016-07-15 Ventana Medical Systems, Inc. 標本處理系統和用於對準載片的方法
US11274998B2 (en) 2012-12-26 2022-03-15 Ventana Medical Systems, Inc. Specimen processing systems and methods for holding slides
CA2890819C (en) * 2012-12-26 2017-05-16 Ventana Medical Systems, Inc. Specimen processing systems and methods for moderating evaporation
US9989448B2 (en) 2012-12-26 2018-06-05 Ventana Medical Systems, Inc. Specimen processing systems and methods for holding slides
CA2892253A1 (en) * 2012-12-26 2014-07-03 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
US9518920B2 (en) 2013-06-26 2016-12-13 Alentic Microscience Inc. Sample processing improvements for microscopy
US10502666B2 (en) 2013-02-06 2019-12-10 Alentic Microscience Inc. Sample processing improvements for quantitative microscopy
USD728120S1 (en) 2013-03-15 2015-04-28 Ventana Medical Systems, Inc. Arcuate member for moving liquids along a microscope slide
ES2939124T3 (es) 2013-04-05 2023-04-19 Roche Diagnostics Hematology Inc Sistemas y procedimientos automatizados para preparar muestras biológicas para su examen
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
CN111500680B (zh) 2013-06-25 2024-04-16 普罗格诺西斯生物科学公司 检测样品中生物靶标的空间分布的方法和系统
CN105793690B (zh) 2013-12-13 2020-01-03 文塔纳医疗系统公司 生物样本的自动化组织学处理及相关的技术
WO2015086531A1 (en) 2013-12-13 2015-06-18 Ventana Medical Systems, Inc. Automated processing systems and methods of thermally processing microscope slides
CA2932492C (en) 2013-12-13 2020-05-12 Ventana Medical Systems, Inc. Staining reagents and other liquids for histological processing of biological specimens and associated technology
WO2015150278A1 (en) * 2014-03-31 2015-10-08 Ventana Medical Systems, Inc. Automated specimen processing systems and multistep processing of microscope slides
CA2947926C (en) * 2014-06-27 2020-03-10 Ventana Medical Systems, Inc. Automated specimen processing systems and methods of detecting specimen-bearing microscope slides
CN104280280B (zh) * 2014-10-13 2016-12-07 赵烨梁 一种微漏进样法制备单分子样品的装置
KR102460969B1 (ko) 2014-10-29 2022-10-31 코닝 인코포레이티드 세포 배양 인서트
JP2017532971A (ja) 2014-10-29 2017-11-09 コーニング インコーポレイテッド 細胞培養集合体を生成するためのマイクロウェル設計および製造
US10209166B2 (en) 2014-11-18 2019-02-19 Alfonso Heras System and method for processing biological specimens
AU2016223550B2 (en) 2015-02-27 2019-07-11 Ventana Medical Systems, Inc. Assay reaction controller magazine
EP4321627A3 (en) 2015-04-10 2024-04-17 10x Genomics Sweden AB Spatially distinguished, multiplex nucleic acid analysis of biological specimens
CN107615039A (zh) * 2015-05-26 2018-01-19 奥林巴斯株式会社 检查体染色装置和检查体染色方法
WO2017001537A1 (en) * 2015-07-02 2017-01-05 Ventana Medical Systems, Inc. Opposables incorporating fluid control elements and automated specimen processing systems
CN105092865B (zh) * 2015-07-23 2017-07-18 爱威科技股份有限公司 试纸条淋样槽、淋样系统、干化分析仪及其淋样与清洗方法
CA2995204A1 (en) 2015-08-10 2017-02-16 Essenlix Corp. Bio/chemical assay devices and methods for simplified steps, small samples, accelerated speed, and ease-of-use
KR20190057445A (ko) 2015-09-14 2019-05-28 에센릭스 코프. 샘플 특히 혈액샘플을 분석하기 위한 장치와 시스템 및 그 사용 방법
US10132794B2 (en) 2015-09-14 2018-11-20 Essenlix Corporation Device and system for collecting and analyzing vapor condensate, particularly exhaled breath condensate, as well as method of using the same
ITUB20155913A1 (it) * 2015-11-26 2017-05-26 Delcon S R L Apparecchiatura e metodo per la colorazione di vetrini
WO2017114750A1 (en) 2015-12-28 2017-07-06 Ventana Medical Systems, Inc. Opposables incorporating onboard reagents and automated specimen processing systems
JP6908624B2 (ja) 2016-04-27 2021-07-28 ベンタナ メディカル システムズ， インコーポレイテッド リアルタイム体積制御するためのシステムおよび方法
DE102016225885B4 (de) * 2016-12-21 2023-12-21 Prime23 GmbH Vorrichtung und Verfahren zum Benetzen von biologischem Material
US10628693B2 (en) 2016-12-21 2020-04-21 Essenlix Corporation Devices and methods for authenticating a sample and use of the same
JP7003158B2 (ja) 2017-02-07 2022-01-20 エッセンリックス コーポレーション 圧縮開放流アッセイおよび使用
US12569851B2 (en) 2017-02-08 2026-03-10 Essenlix Corporation Digital assay
CA3053002A1 (en) 2017-02-08 2018-08-16 Essenlix Corp. Bio/chemical material extraction and assay
CA3052809A1 (en) 2017-02-08 2018-08-23 Essenlix Corporation Qmax assays and applications
CN122234927A (zh) 2017-02-08 2026-06-19 上海宜晟生物科技有限公司 通过控制温度的分子操作和检测
WO2018148470A1 (en) 2017-02-08 2018-08-16 Essenlix Corporation Sample collection and handling for delayed analysis
CN106706398B (zh) * 2017-02-08 2024-06-07 爱威科技股份有限公司 一种样本染色装置
CA3053132A1 (en) 2017-02-09 2018-08-16 Essenlix Corp. Assay with amplification
JP2020507770A (ja) 2017-02-09 2020-03-12 エッセンリックス コーポレーション 比色アッセイ法
CA3053114A1 (en) 2017-02-09 2018-08-16 Essenlix Corporation Assay using different spacing heights
US12017218B2 (en) * 2017-02-15 2024-06-25 International Business Machines Corporation Hybrid microfluidics devices
CA3053295A1 (en) 2017-02-15 2018-08-23 Essenlix Corporation Assay with rapid temperature change
CN111448449B (zh) 2017-02-16 2024-08-27 上海宜晟生物科技有限公司 采用纹理化表面的测定方法及装置
CN110462370A (zh) * 2017-03-31 2019-11-15 X-Zell公司 自动载玻片染色和冷却系统
JP7335816B2 (ja) 2017-05-23 2023-08-30 エッセンリックス コーポレーション アッセイのための急速な試料温度変化
CN110637222A (zh) * 2017-05-26 2019-12-31 文塔纳医疗系统公司 非接触式、在载玻片上的流体混合
US12181472B2 (en) 2017-06-12 2024-12-31 Essenlix Corporation Homogeneous assay
CN111051494B (zh) 2017-07-14 2024-03-29 康宁股份有限公司 用于手动或自动培养基交换的3d细胞培养容器
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
US11725227B2 (en) 2017-08-01 2023-08-15 Essenlix Corporation Devices and methods for examining drug effects on microorganisms
CN111492222A (zh) 2017-08-01 2020-08-04 Essenlix公司 样品收集、保持和测定
US11280706B2 (en) 2017-08-01 2022-03-22 Essenlix Corporation Dilution calibration
WO2019058857A1 (ja) 2017-09-21 2019-03-28 浜松ホトニクス株式会社 試料支持体
WO2019075244A1 (en) 2017-10-11 2019-04-18 Essenlix Corporation CONTAINING A LIQUID SAMPLE
WO2019075415A1 (en) 2017-10-13 2019-04-18 Essenlix Corporation DEVICES AND METHODS FOR AUTHENTICATING MEDICAL ANALYSIS AND USES THEREOF
JP7046969B2 (ja) * 2017-10-25 2022-04-04 株式会社日立ハイテク 生物組織試料の作成方法、及び生物組織片試料の観察方法
US11237113B2 (en) 2017-10-26 2022-02-01 Essenlix Corporation Rapid pH measurement
US10807095B2 (en) 2017-10-26 2020-10-20 Essenlix Corporation Making and tracking assay card
US11609224B2 (en) 2017-10-26 2023-03-21 Essenlix Corporation Devices and methods for white blood cell analyses
WO2019118652A1 (en) 2017-12-12 2019-06-20 Essenlix Corporation Sample manipulation and assay with rapid temperature change
CN112534259A (zh) 2017-12-14 2021-03-19 Essenlix公司 监测毛发的装置，系统和方法
EP3729047A2 (en) 2017-12-24 2020-10-28 Ventana Medical Systems, Inc. Eosin staining techniques
CN111492225A (zh) 2017-12-24 2020-08-04 文塔纳医疗系统公司 无酚抗酸染色组合物及其用途
WO2019140334A1 (en) 2018-01-11 2019-07-18 Essenlix Corporation Homogeneous assay (ii)
WO2019137980A1 (en) 2018-01-11 2019-07-18 Ventana Medical Systems, Inc. Anti-fogging barcode reader
JP7171696B2 (ja) 2018-07-13 2022-11-15 コーニング インコーポレイテッド 相互接続されたウェルを有するマイクロプレートを備えた流体デバイス
EP3649229B1 (en) 2018-07-13 2021-08-25 Corning Incorporated Cell culture vessels with stabilizer devices
US11912968B2 (en) 2018-07-13 2024-02-27 Corning Incorporated Microcavity dishes with sidewall including liquid medium delivery surface
WO2020016127A2 (en) 2018-07-16 2020-01-23 Ventana Medical Systems, Inc. Automated slide processing systems, consumable slide processing modules, and reagent cartridges
EP3824265B1 (en) 2018-07-16 2024-02-14 Ventana Medical Systems, Inc. Automated staining system
US11885952B2 (en) 2018-07-30 2024-01-30 Essenlix Corporation Optics, device, and system for assaying and imaging
EP3894585A2 (en) 2018-12-10 2021-10-20 10X Genomics, Inc. Generating capture probes for spatial analysis
US12529094B2 (en) 2018-12-10 2026-01-20 10X Genomics, Inc. Imaging system hardware
KR102833793B1 (ko) * 2018-12-20 2025-07-16 라이카 바이오시스템즈 멜버른 피티와이 엘티디 슬라이드 출력 모듈
MX392907B (es) * 2019-02-21 2025-03-20 Jesùs Raùl Beltran Ramìrez Aparato para el procesamiento inmunohistoquímico de múltiples muestras histológicas
US11712177B2 (en) 2019-08-12 2023-08-01 Essenlix Corporation Assay with textured surface
US12669692B2 (en) * 2019-10-16 2026-06-30 Hitachi High-Tech Corporation Microscope slide and method for selecting the same
US12157124B2 (en) 2019-11-06 2024-12-03 10X Genomics, Inc. Imaging system hardware
US11768175B1 (en) 2020-03-04 2023-09-26 10X Genomics, Inc. Electrophoretic methods for spatial analysis
US11846643B2 (en) * 2020-03-27 2023-12-19 Alpha Technologies Services Llc Test sample handling system with rotary carousel
DE102020204670A1 (de) * 2020-04-14 2021-10-14 Prime23 GmbH Vorrichtung und Verfahren zum Benetzen von biologischen Material mit wenigstens einer Flüssigkeit sowie eine Halteeinrichtung
US12031177B1 (en) 2020-06-04 2024-07-09 10X Genomics, Inc. Methods of enhancing spatial resolution of transcripts
EP4421186B1 (en) 2020-06-08 2025-08-13 10X Genomics, Inc. Methods of determining a surgical margin and methods of use thereof
EP4164796A4 (en) 2020-06-10 2024-03-06 10x Genomics, Inc. Fluid delivery methods
CN116194590A (zh) 2020-09-18 2023-05-30 10X基因组学有限公司 样品处理设备和图像配准方法
WO2022140028A1 (en) 2020-12-21 2022-06-30 10X Genomics, Inc. Methods, compositions, and systems for capturing probes and/or barcodes
EP4348330A4 (en) * 2021-05-27 2025-05-07 Scopio Labs Ltd. SYSTEMS AND METHODS FOR COVER GLASS
ES3030033T3 (en) 2021-06-03 2025-06-26 10X Genomics Inc Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis
EP4433796A4 (en) * 2021-11-19 2025-10-22 Univ Cornell OMNIPHOBIC TILES (DOTS) WITH SURFACE PATTERNS, ASSOCIATED MANUFACTURE, LOADING AND USE
EP4305195A2 (en) 2021-12-01 2024-01-17 10X Genomics, Inc. Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis
EP4441711A1 (en) 2021-12-20 2024-10-09 10X Genomics, Inc. Self-test for pathology/histology slide imaging device
US12686138B2 (en) 2022-07-01 2026-07-21 Toyota Research Institute Dual flow integrated suction tool for robotic end-effectors
CN120344649A (zh) * 2022-11-15 2025-07-18 沃特世科技公司 压制和混合的薄膜酶反应器及其制备方法
WO2024237277A1 (ja) * 2023-05-18 2024-11-21 株式会社Ｓｃｒｅｅｎホールディングス 標本封入方法および標本封入装置
CN121909386A (zh) * 2023-07-25 2026-04-21 直观罗斯公司 用于自动化系统的染色方法
CN117717967B (zh) * 2023-12-18 2026-05-22 季华实验室 一种有机薄膜晶体材料一体化自动制备平台

Family Cites Families (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3556633A (en) 1969-01-17 1971-01-19 Winifred Liu Mutschmann Specimen carrying slide with runoff trough
US3551023A (en) 1969-01-17 1970-12-29 Ibm Pathology specimen processing method and article
US3672745A (en) 1970-06-29 1972-06-27 Propper Mfg Co Inc Bevelled edge microscope slide
GB1457137A (en) 1973-08-16 1976-12-01 Wyeth John & Brother Ltd Apparatus for handling coverslips
FR2263502B1 (enExample) * 1974-03-06 1976-12-10 Ass Ctre Transfusion San
US3961346A (en) 1975-01-30 1976-06-01 Miles Laboratories, Inc. Liquid inspection slide
US4023949A (en) 1975-08-04 1977-05-17 Schlom Leslie A Evaporative refrigeration system
SE403940B (sv) 1976-02-26 1978-09-11 Cytologiska Centrallab Sett och anordning for maskinell applicering av teckplattor pa med preparat for mikroskopisk undersokning forsedda objektglas
US4203797A (en) 1977-05-09 1980-05-20 Cytologiska Centrallaboratoriet Ab Method of and apparatus for applying cover-slips to slides carrying specimens for microscopic examination
US4146414A (en) 1977-05-09 1979-03-27 Cytologiska Centrallaboratoriet Ab Method for applying cover-slips to slides carrying specimens for microscopic examination
US4418527A (en) 1980-04-21 1983-12-06 Schlom Leslie A Precooler for gas turbines
US4359013A (en) 1980-09-08 1982-11-16 Prevo Donald L Device for spreading monolayered films
US4392450A (en) 1981-02-12 1983-07-12 Prevo Donald L Device for spreading monolayered films
US4336765A (en) 1981-06-12 1982-06-29 Coughlin Vincent D Vacuum work piece holder
JPS58140457U (ja) * 1982-03-18 1983-09-21 明星電気株式会社 顕微鏡標本作成装置の試料固定機構
US4428793A (en) 1981-08-25 1984-01-31 Meisei Electric Co., Ltd. Preparation method for a microscopic specimen and a device therefor
JPS5840519A (ja) * 1981-09-03 1983-03-09 Meisei Electric Co Ltd 顕微鏡用標本の封入方法
US4597982A (en) 1982-03-18 1986-07-01 Delameter William D Method for processing flexible sheets
US5023187A (en) 1985-09-13 1991-06-11 Fisher Scientific Company Method and device for accelerated treatment of thin sample on surface
US4731335A (en) 1985-09-13 1988-03-15 Fisher Scientific Company Method for treating thin samples on a surface employing capillary flow
US4790640A (en) 1985-10-11 1988-12-13 Nason Frederic L Laboratory slide
US5002736A (en) 1987-03-31 1991-03-26 Fisher Scientific Co. Microscope slide and slide assembly
US4849340A (en) 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
GB8722902D0 (en) 1987-09-30 1987-11-04 Shandon Southern Prod Tissue &c processing
US5503803A (en) 1988-03-28 1996-04-02 Conception Technologies, Inc. Miniaturized biological assembly
US4911782A (en) 1988-03-28 1990-03-27 Cyto-Fluidics, Inc. Method for forming a miniaturized biological assembly
US5281516A (en) 1988-08-02 1994-01-25 Gene Tec Corporation Temperature control apparatus and method
US5188963A (en) 1989-11-17 1993-02-23 Gene Tec Corporation Device for processing biological specimens for analysis of nucleic acids
US5346672A (en) 1989-11-17 1994-09-13 Gene Tec Corporation Devices for containing biological specimens for thermal processing
US5595707A (en) 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
SG49766A1 (en) 1990-03-30 1998-06-15 Neuromedical Systems Inc Automated cytological specimen classification system and method
US5075079A (en) 1990-05-21 1991-12-24 Technicon Instruments Corporation Slide analysis system
US5273905A (en) 1991-02-22 1993-12-28 Amoco Corporation Processing of slide mounted material
US5189751A (en) 1991-03-21 1993-03-02 Gemtech, Inc. Vibrating toothbrush using a magnetic driver
JP3320444B2 (ja) 1992-04-06 2002-09-03 株式会社千代田製作所 染色装置用ノズル洗浄装置
US5256241A (en) 1992-08-28 1993-10-26 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method for controlling protein crystallization
NO179729C (no) 1992-12-11 1996-12-04 Oeystein H Ljungmann Apparat for automatisk påklebing av dekkglass på objektglass
US5364790A (en) 1993-02-16 1994-11-15 The Perkin-Elmer Corporation In situ PCR amplification system
JP3292765B2 (ja) 1993-07-30 2002-06-17 株式会社千代田製作所 顕微鏡標本の染色方法とその装置
AUPM352194A0 (en) 1994-01-25 1994-02-17 Australian Biomedical Corporation Limited Instrument for automatically applying coverslips and method
AUPN038995A0 (en) 1995-01-05 1995-01-27 Australian Biomedical Corporation Limited Method and apparatus for human or animal cell sample treatment
GB9506312D0 (en) 1995-03-28 1995-05-17 Medical Res Council Improvements in or relating to sample processing
AUPN357495A0 (en) 1995-06-15 1995-07-06 Australian Biomedical Corporation Limited Coverslip pick-up and laydown apparatus
JPH0943118A (ja) * 1995-07-31 1997-02-14 Aloka Co Ltd 生物組織の処理装置
GB9518129D0 (en) 1995-09-06 1995-11-08 Zynocyte Ltd Stain and capillary slide
US5650332A (en) 1995-11-14 1997-07-22 Coulter International Corp. Method for the preparation of microscope slides
DE69733745T2 (de) * 1996-01-16 2006-04-20 World Properties, Inc., Lincolnwood Mit walze beschichtetes elektrolumineszentes paneel
AUPN762196A0 (en) 1996-01-17 1996-02-08 Australian Biomedical Corporation Limited Specimen preparation apparatus
AUPN923596A0 (en) * 1996-04-12 1996-05-09 Australian Biomedical Corporation Limited Method and apparatus for treatment of human or animal cell samples
EP1007955B1 (en) 1996-05-06 2003-11-26 Helena Laboratories Corporation Apparatus for the application of samples on a substrate
JP3419430B2 (ja) 1996-08-21 2003-06-23 日本電子株式会社 生化学自動分析装置における試薬注入攪拌装置
JP3753526B2 (ja) 1996-12-18 2006-03-08 サクラ精機株式会社 顕微鏡標本のカバーガラス貼着方法と装置
US6703247B1 (en) 1996-12-23 2004-03-09 American Registry Of Pathology Apparatus and methods for efficient processing of biological samples on slides
AUPO439496A0 (en) * 1996-12-24 1997-01-23 Australian Biomedical Corporation Pty. Ltd. Smearer mechanism
JPH10197424A (ja) * 1997-01-14 1998-07-31 Chiyoda Manufacturing Co Ltd 顕微鏡標本のカバーガラス取付け方法及び装置
US6489171B1 (en) 1997-04-18 2002-12-03 Cell Marque Corporation Chemical dispensing system and method
US5812312A (en) 1997-09-04 1998-09-22 Lorincz; Andrew Endre Microscope slide
US6567214B2 (en) 1997-09-04 2003-05-20 Andrew E. Lorincz Microscope slide having culture media and method for use
US6239906B1 (en) 1997-09-04 2001-05-29 Andrew E. Lorincz Flexible microscope slide
US6486947B2 (en) 1998-07-22 2002-11-26 Ljl Biosystems, Inc. Devices and methods for sample analysis
AU1752499A (en) 1997-12-23 1999-07-19 Dako A/S Cartridge device for processing a sample mounted on a surface of a support member
US6083759A (en) 1997-12-30 2000-07-04 University Of Hawaii Blood smearing cassette
US6037168A (en) 1997-12-31 2000-03-14 Cytonix Corporation Microbiological assembly comprising resealable closure means
JPH11202215A (ja) * 1998-01-09 1999-07-30 Chiyoda Mfg Co Ltd 顕微鏡標本のカバーガラス貼着方法と装置
US6589650B1 (en) 2000-08-07 2003-07-08 3M Innovative Properties Company Microscope cover slip materials
EP1073892B1 (en) * 1998-02-27 2010-11-24 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
US20030211630A1 (en) 1998-02-27 2003-11-13 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
WO1999049295A1 (en) 1998-03-24 1999-09-30 Biogenex Laboratories Automated staining apparatus
US6358475B1 (en) 1998-05-27 2002-03-19 Becton, Dickinson And Company Device for preparing thin liquid for microscopic analysis
US6180314B1 (en) 1998-05-27 2001-01-30 Becton, Dickinson And Company Method for preparing thin liquid samples for microscopic analysis
NO986025D0 (no) 1998-12-21 1998-12-21 Torstein Ljungmann Maskin for automatisk pÕklebing av dekkglass pÕ objektglass
US6544798B1 (en) 1999-02-26 2003-04-08 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US6568447B1 (en) 1999-05-11 2003-05-27 Kabushiki Kaisha Tiyoda Seisakusho Cover glass adhering device
US6474386B2 (en) 1999-08-25 2002-11-05 Kabushiki Kaisha Tiyoda Seisakusho Cover glass adhering device
US6403931B1 (en) 1999-10-07 2002-06-11 Ventana Medical Systems, Inc. Slide heater calibrator and temperature converter apparatus and method
AU2922701A (en) 1999-11-04 2001-05-14 Arcturus Engineering, Inc. Automated laser capture microdissection
USD445909S1 (en) 1999-11-11 2001-07-31 Hemocue Ab Cuvette
NO310385B1 (no) 1999-11-17 2001-06-25 Torstein Ljungmann Anordning for automatisk påklebing av dekkglass på objektglass
ES2312416T3 (es) 2000-02-23 2009-03-01 Schlom, Leslie Un intercambiador de calor de enfriammiento y de preenfriamiento para el acondicionamiento del aire de admision de un turbina.
USD464141S1 (en) 2000-10-17 2002-10-08 Acon Laboratories, Inc. Test device platform
US6717657B2 (en) 2001-01-02 2004-04-06 Becton, Dickinson And Company Apparatus for measuring the volume of individual red blood cells
US6544793B2 (en) 2001-04-27 2003-04-08 Becton, Dickinson And Company Method for calibrating a sample analyzer
US6485918B1 (en) * 2001-07-02 2002-11-26 Packard Bioscience Corporation Method and apparatus for incubation of a liquid reagent and target spots on a microarray substrate
DE10144048B4 (de) 2001-09-07 2012-09-20 Leica Mikrosysteme Gmbh Vorrichtung und Verfahren zum Handhaben von Deckgläsern für Objektträger
US7425306B1 (en) 2001-09-11 2008-09-16 Ventana Medical Systems, Inc. Slide heater
US20030087292A1 (en) 2001-10-04 2003-05-08 Shiping Chen Methods and systems for promoting interactions between probes and target molecules in fluid in microarrays
US7468161B2 (en) * 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
US7271006B2 (en) 2002-04-26 2007-09-18 Ventana Medical Systems, Inc. Method and apparatus for automated coverslipping
DK1499872T3 (en) * 2002-04-26 2015-12-14 Ventana Med Syst Inc AUTOMATED MOLECULAR PATHOLOGY DEVICE WITH SOLID SLIDING PLATES
US7919308B2 (en) 2002-06-14 2011-04-05 Agilent Technologies, Inc. Form in place gaskets for assays
AUPS309002A0 (en) * 2002-06-20 2002-07-11 Vision Biosystems Limited A covertile for a substrate
WO2004001390A1 (en) 2002-06-20 2003-12-31 Vision Biosystems Limited Biological reaction apparatus with draining mechanism
US7063758B2 (en) 2002-07-29 2006-06-20 Three Bond Co., Ltd. Laminating apparatus and laminating method
US7452712B2 (en) 2002-07-30 2008-11-18 Applied Biosystems Inc. Sample block apparatus and method of maintaining a microcard on a sample block
USD495806S1 (en) 2002-08-08 2004-09-07 Exiqon A/S Slide for use in chemical or biochemical procedures
US7186383B2 (en) 2002-09-27 2007-03-06 Ast Management Inc. Miniaturized fluid delivery and analysis system
US20040082058A1 (en) 2002-10-29 2004-04-29 Arthur Schleifer Array hybridization apparatus and method for making uniform sample volumes
US7850912B2 (en) 2003-05-14 2010-12-14 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
WO2004083824A1 (en) 2003-03-20 2004-09-30 Dakocytomation Denmark A/S System for establishing a sample cover on a substrate
US7468160B2 (en) 2003-12-05 2008-12-23 Agilent Technologies, Inc. Devices and methods for performing array based assays
JP4871737B2 (ja) 2003-12-23 2012-02-08 ベンタナ・メデイカル・システムズ・インコーポレーテツド 平坦な表面の効率的な薄膜液体処理のための方法および装置
DK1771730T3 (da) * 2004-07-23 2014-09-08 Ventana Med Syst Inc Fremgangsmåde og apparat til påføring af væsker til en biologisk prøve
DE102004037848B4 (de) 2004-08-04 2007-03-29 Advalytix Ag Probenträgerwaschbehälter, Probenträgerwaschstation, System zum Waschen von Probenträgern und Verfahren zum Waschen von Probenträgern
US7481980B2 (en) 2004-09-08 2009-01-27 Intavis Bioanalytical Instruments Ag Device for staining and hybridization reactions
US7300804B2 (en) 2004-11-15 2007-11-27 Beckman Coulter, Inc. Method and apparatus for controlling the uniform smearing of a biological liquid over a substrate
US7838283B2 (en) * 2005-04-21 2010-11-23 Celerus Diagnostics, Inc. Wicking cassette method and apparatus for automated rapid immunohistochemistry
JP4607703B2 (ja) * 2005-08-22 2011-01-05 東芝機械株式会社 薄切片標本作製方法
WO2007122265A1 (en) 2006-04-26 2007-11-01 Quantifoil Instruments Gmbh A sample handling device for and a method of handling a sample
USD569990S1 (en) 2006-09-28 2008-05-27 Millennium Sciences Microscope slide assembly
US20110217731A1 (en) 2008-06-16 2011-09-08 Mayo Foundation For Medical Education And Research Pathology sample processing workstation
US9072576B2 (en) 2008-12-08 2015-07-07 Sunstar Inc. Linear actuator
WO2010074917A1 (en) 2008-12-24 2010-07-01 Ventana Medical Systems, Inc. Microscope-slide dryer
EP2499500B1 (en) 2009-11-13 2020-12-30 Ventana Medical Systems, Inc. Thin film processing apparatuses for adjustable volume accommodation
US9498791B2 (en) 2009-11-13 2016-11-22 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
WO2011139978A1 (en) 2010-05-04 2011-11-10 Ventana Medical Systems, Inc. Moving meniscus rinsing and mixing in cell staining
USD645971S1 (en) 2010-05-11 2011-09-27 Claros Diagnostics, Inc. Sample cassette
US20110305842A1 (en) 2010-06-11 2011-12-15 Ventana Medical Systems, Inc. Floatable opposables for applying fluids to process biological samples
EP2819775A1 (en) 2012-03-01 2015-01-07 Victorious Medical Systems ApS Method and system for distributing and agitating an amount of liquid over a microscope slide
ES2637775T3 (es) 2012-12-26 2017-10-17 Ventana Medical Systems, Inc. Sistemas de procesamiento de especímenes y métodos para la preparación de reactivos
CA2892253A1 (en) 2012-12-26 2014-07-03 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
USD728120S1 (en) 2013-03-15 2015-04-28 Ventana Medical Systems, Inc. Arcuate member for moving liquids along a microscope slide

Also Published As

Publication number Publication date
AU2010320039A1 (en) 2012-05-03
JP5923145B2 (ja) 2016-05-24
WO2011060387A1 (en) 2011-05-19
KR101358549B1 (ko) 2014-02-05
US20150071833A1 (en) 2015-03-12
JP2015007646A (ja) 2015-01-15
EP2499500A4 (en) 2016-01-06
US8911815B2 (en) 2014-12-16
IL219086A0 (en) 2012-06-28
BR112012011181A2 (pt) 2020-10-13
KR20120107074A (ko) 2012-09-28
CA2778837C (en) 2016-01-19
US9618430B2 (en) 2017-04-11
US20130052331A1 (en) 2013-02-28
CN102687023B (zh) 2016-01-06
JP2013511048A (ja) 2013-03-28
CN102687023A (zh) 2012-09-19
IL219086A (en) 2017-10-31
EP2499500B1 (en) 2020-12-30
HK1175845A1 (zh) 2013-07-12
AU2010320039B2 (en) 2013-08-15
CA2778837A1 (en) 2011-05-19
IN2012DN03245A (enExample) 2015-10-23
EP2499500A1 (en) 2012-09-19

Similar Documents

Publication Publication Date Title
JP5923145B2 (ja) 調整可能な体積を収容する薄膜処理装置
US9989448B2 (en) Specimen processing systems and methods for holding slides
EP2938996B1 (en) Automated specimen processing systems and methods of using the same
EP2938994B1 (en) Specimen processing systems and methods for aligning slides
US20220268673A1 (en) Specimen processing systems and methods for holding slides
EP2939030B1 (en) Specimen processing systems and method for uniformly heating slides
WO2011002779A2 (en) Methods and apparatuses for applying and removing fluids for processing biological samples
US20110305842A1 (en) Floatable opposables for applying fluids to process biological samples
US20150293341A1 (en) Specimen processing systems and methods for aligning slides
AU2013369470B2 (en) Specimen processing systems and methods for moderating evaporation
HK1175845B (en) Thin film processing apparatuses for adjustable volume accommodation

Legal Events

Date Code Title Description
A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20130927

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20131002

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20131220

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20140804

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20140902

R150 Certificate of patent or registration of utility model

Ref document number: 5611363

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees