CA2732098C - Compositions comprising sweetness enhancers and methods of making them - Google Patents

Compositions comprising sweetness enhancers and methods of making them Download PDF

Info

Publication number
CA2732098C
CA2732098C CA2732098A CA2732098A CA2732098C CA 2732098 C CA2732098 C CA 2732098C CA 2732098 A CA2732098 A CA 2732098A CA 2732098 A CA2732098 A CA 2732098A CA 2732098 C CA2732098 C CA 2732098C
Authority
CA
Canada
Prior art keywords
sweetener
ingestible composition
composition
ppm
benzo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2732098A
Other languages
English (en)
French (fr)
Other versions
CA2732098A1 (en
Inventor
Rhondi Shigemura
Carolyn Podgurski
Boriruck Kitisin
Jennifer Ward
Ana Alatorre
Thitiwan Lebien
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Firmenich Inc
Original Assignee
Senomyx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senomyx Inc filed Critical Senomyx Inc
Publication of CA2732098A1 publication Critical patent/CA2732098A1/en
Application granted granted Critical
Publication of CA2732098C publication Critical patent/CA2732098C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/13—Fermented milk preparations; Treatment using microorganisms or enzymes using additives
    • A23C9/1307—Milk products or derivatives; Fruit or vegetable juices; Sugars, sugar alcohols, sweeteners; Oligosaccharides; Organic acids or salts thereof or acidifying agents; Flavours, dyes or pigments; Inert or aerosol gases; Carbonation methods
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/154—Milk preparations; Milk powder or milk powder preparations containing additives containing thickening substances, eggs or cereal preparations; Milk gels
    • A23C9/1544—Non-acidified gels, e.g. custards, creams, desserts, puddings, shakes or foams, containing eggs or thickening or gelling agents other than sugar; Milk products containing natural or microbial polysaccharides, e.g. cellulose or cellulose derivatives; Milk products containing nutrient fibres
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/156—Flavoured milk preparations ; Addition of fruits, vegetables, sugars, sugar alcohols or sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/56—Liquid products; Solid products in the form of powders, flakes or granules for making liquid products, e.g. for making chocolate milk, drinks and the products for their preparation, pastes for spreading or milk crumb
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L21/00—Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10—Cereal-derived products
    • A23L7/117—Flakes or other shapes of ready-to-eat type; Semi-finished or partly-finished products therefor
    • A23L7/122—Coated, filled, multilayered or hollow ready-to-eat cereals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L9/00—Puddings; Cream substitutes; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2200/00—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Seasonings (AREA)
  • Medicinal Preparation (AREA)
CA2732098A 2008-07-31 2009-07-30 Compositions comprising sweetness enhancers and methods of making them Expired - Fee Related CA2732098C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8522808P 2008-07-31 2008-07-31
US61/085,228 2008-07-31
PCT/US2009/052258 WO2010014813A2 (en) 2008-07-31 2009-07-30 Compositions comrpising sweetness enhancers and methods of making them

Publications (2)

Publication Number Publication Date
CA2732098A1 CA2732098A1 (en) 2010-02-04
CA2732098C true CA2732098C (en) 2016-11-22

Family

ID=41610958

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2732098A Expired - Fee Related CA2732098C (en) 2008-07-31 2009-07-30 Compositions comprising sweetness enhancers and methods of making them

Country Status (11)

Country Link
US (1) US8609173B2 (enExample)
EP (1) EP2328426B1 (enExample)
JP (1) JP5723275B2 (enExample)
CN (1) CN102170797B (enExample)
BR (1) BRPI0916550B1 (enExample)
CA (1) CA2732098C (enExample)
DK (1) DK2328426T3 (enExample)
ES (1) ES2525551T3 (enExample)
MX (1) MX2011001155A (enExample)
RU (1) RU2511315C2 (enExample)
WO (1) WO2010014813A2 (enExample)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
EP3085699B1 (en) 2008-07-31 2022-03-02 Firmenich Incorporated Processes for making sweet taste enhancers
BRPI0921625A2 (pt) 2008-11-04 2016-01-05 Univ Kentucky Res Foundation Inc composicoes baseadas em d-tagatose e metodos para previnir e tratar aterosclerose, sindrome metabolica, e sintomas dos mesmos
US8293299B2 (en) 2009-09-11 2012-10-23 Kraft Foods Global Brands Llc Containers and methods for dispensing multiple doses of a concentrated liquid, and shelf stable Concentrated liquids
US10888099B2 (en) 2009-11-12 2021-01-12 Purecircle Sdn Bhd. Granulation of a Stevia sweetener
JP5840682B2 (ja) * 2010-06-25 2016-01-06 フイルメニツヒ ソシエテ アノニムＦｉｒｍｅｎｉｃｈ Ｓａ 成分送達系
MX2012014060A (es) * 2010-06-29 2012-12-17 Firmenich & Cie Sistema de suministro de ingredientes activos.
CN103153096B (zh) 2010-08-12 2016-08-03 赛诺米克斯公司 提高甜味增强剂的稳定性的方法和包含稳定的甜味增强剂的组合物
US8563030B1 (en) * 2011-08-22 2013-10-22 Mallory Kievman Singultus-stopping article and composition
CN102551027A (zh) * 2011-12-20 2012-07-11 苏州工业园区尚融科技有限公司 复合无糖型甜味剂及其制备方法
GB201202797D0 (en) * 2012-02-20 2012-04-04 Eminate Ltd Sodium bicarbonate product
AU2013223143B2 (en) * 2012-02-21 2017-12-21 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of cancer
WO2013158928A2 (en) 2012-04-18 2013-10-24 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies
EP2659789B1 (de) * 2012-05-04 2019-05-01 Symrise AG Stoffgemische
US11013248B2 (en) 2012-05-25 2021-05-25 Kraft Foods Group Brands Llc Shelf stable, concentrated, liquid flavorings and methods of preparing beverages with the concentrated liquid flavorings
JP2013243992A (ja) * 2012-05-29 2013-12-09 Q P Corp フィリング
AU2013299859B2 (en) 2012-08-06 2017-06-15 Firmenich Incorporated Sweet flavor modifier
US20140171519A1 (en) 2012-12-19 2014-06-19 Indra Prakash Compositions and methods for improving rebaudioside x solubility
EP2934181B1 (en) 2012-12-19 2019-09-25 The Coca-Cola Company Compositions and methods for improving rebaudioside x solubility
WO2014095674A1 (en) * 2012-12-21 2014-06-26 Firmenich Sa Co-crystallized sweeteners
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
GB2520276A (en) * 2013-11-13 2015-05-20 Tate & Lyle Technology Ltd High intensity sweetener composition
RU2555032C1 (ru) * 2014-01-24 2015-07-10 Общество с ограниченной ответственностью Торговый дом "МИЛИСС" Порошкообразная смесь для приготовления безалкогольного напитка (варианты)
US20160242439A1 (en) 2014-04-04 2016-08-25 Douxmatok Ltd Method for producing sweetener compositions and sweetener compositions
CN103919206A (zh) * 2014-04-14 2014-07-16 杭州佳禾食品有限公司 一种牛奶伴侣果汁饮料及其制备方法
EP3142498B1 (en) * 2014-05-09 2018-06-20 Firmenich SA Solubilization of a sweet modulator and flavor
US20150366252A1 (en) * 2014-06-24 2015-12-24 International Flavors & Fragrances Inc. Sweetener enhancers and methods for using the same
KR101716734B1 (ko) * 2015-03-05 2017-03-15 씨제이제일제당(주) 전자레인지 조리용 잼 믹스 조성물, 이를 이용한 잼 및 이의 제조 방법
CN104839351A (zh) * 2015-04-28 2015-08-19 三江侗族自治县仙池茶业有限公司 一种含甜叶菊糖苷天然抗氧化剂且具甜味的茶籽油
WO2017037531A2 (en) * 2015-08-28 2017-03-09 Douxmatok Ltd Method for producing sweetener compositions and sweetener compositions
JP6949838B2 (ja) 2015-10-29 2021-10-13 フィルメニッヒ インコーポレイテッドＦｉｒｍｅｎｉｃｈ Ｉｎｃｏｒｐｏｒａｔｅｄ 高甘味度甘味料
CN109219355B (zh) * 2016-04-06 2023-03-07 可口可乐公司 甜菊醇糖苷或罗汉果苷甜味剂的甜度和味道改善
JP7228511B2 (ja) * 2016-11-16 2023-02-24 ザ コカ・コーラ カンパニー ミラクルフルーツによるステビア甘味飲料の味覚改善
EP3342294B1 (en) * 2016-12-30 2021-03-17 Red Bull GmbH Compositions, in particular sweetening compositions
US11076619B2 (en) 2016-12-30 2021-08-03 Red Bull Gmbh Sweetening compositions
JP7088936B2 (ja) * 2016-12-30 2022-06-21 レッド・ブル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 甘味付与用組成物
US10301275B2 (en) 2017-03-17 2019-05-28 Altria Client Services Llc Sweet taste modulators
CN111108213B (zh) 2017-05-03 2024-12-13 弗门尼舍公司 制备高强度甜味剂的方法
CN110996920A (zh) 2017-07-26 2020-04-10 太杰先软嚼有限责任公司 用于兽医应用的无淀粉软咀嚼物
US11006659B2 (en) 2017-09-26 2021-05-18 King Saud University Fortified date fruit product
WO2019071187A1 (en) 2017-10-06 2019-04-11 Cargill, Incorporated STABILIZED GLYCOSIDE COMPOSITIONS OF STEVIOL AND USES THEREOF
KR102521024B1 (ko) * 2017-10-31 2023-04-13 씨제이제일제당 주식회사 타가토스를 포함하는 후리카케 및 이의 제조방법
WO2019145263A1 (de) * 2018-01-26 2019-08-01 Katjes Fassin Gmbh. + Co. Kommanditgesellschaft ZUCKERREDUZIERTE SÜßWARE
AU2019312481A1 (en) * 2018-07-24 2021-01-21 Dsm Ip Assets B.V. Steviol glycoside aggregates with specific particle size distribution
CN109007749B (zh) * 2018-07-26 2022-04-01 武汉市华甜生物科技有限公司 用于调味酱中的含爱德万甜的复合甜味剂及其制备方法和应用
WO2020033420A1 (en) 2018-08-07 2020-02-13 Firmenich Incorporated 5-substituted 4-amino-1h-benzo[c][1,2,6]thiadiazine 2,2-dioxides and formulations and uses thereof
US12338476B2 (en) 2018-11-07 2025-06-24 Firmenich Incorporated Methods for making high intensity sweeteners
CN113286523A (zh) 2018-11-07 2021-08-20 弗门尼舍公司 制备高强度甜味剂的方法
BR112021019948A2 (pt) 2019-04-06 2021-12-14 Cargill Inc Intensificador de solubilidade de glicosídeo de esteviol, solução aquosa de glicosídeo de esteviol, e, bebida não alcoólica
BR112021019811A2 (pt) 2019-04-06 2021-12-07 Cargill Inc Composição de glicosídeo de esteviol, bebida, métodos para reduzir um atributo sensorial indesejável de uma solução aquosa de glicosídeo de esteviol, para reduzir a persistência de doçura de um componente de glicosídeo de esteviol em uma composição comestível e para reduzir o amargor de um componente de glicosídeo de esteviol em uma composição comestível, e, soluções aquosa de glicosídeo de esteviol com reduzida persistência de doçura e aquosa de glicosídeo de esteviol com reduzido amargor
WO2021118864A1 (en) * 2019-12-13 2021-06-17 Firmenich Incorporated Taste modifying compositions and uses thereof
BR112022009553A2 (pt) * 2019-12-13 2022-08-02 Firmenich Incorporated Composições modificadoras de sabor e usos das mesmas
US12662504B2 (en) 2019-12-27 2026-06-23 Suntory Holdings Limited High-solubility rebaudioside D complex
EP3915397B1 (en) 2020-05-25 2024-11-20 BRAIN Biotech AG Use of a sweet protein for ehancing the sweet taste and/or sweet quality
US20220330578A1 (en) * 2021-04-20 2022-10-20 Sayso Beverages, Inc. Infusible beverage compositions and uses thereof
WO2024206222A1 (en) * 2023-03-24 2024-10-03 The Coca-Cola Company Sweetness and taste improvement of non-sucrose sweeteners with hydroxybenzoic acid
CN121512216A (zh) * 2024-08-13 2026-02-13 思摩尔国际控股有限公司 用于雾化液的甜味组合物、雾化液及其制备方法和雾化装置

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3278532A (en) 1964-07-06 1966-10-11 Sandoz Ag Dioxybenzothiadiazines
US3843804A (en) 1971-03-10 1974-10-22 Int Flavors & Fragrances Inc Novel flavoring compositions and processes
US3857972A (en) 1971-03-10 1974-12-31 Int Flavors & Fragrances Inc Flavoring with an oxocyclic pyrimidine
FI54312C (fi) 1972-05-09 1978-11-10 Sumitomo Chemical Co Foerfarande foer framstaellning av tieno-(2,3-d)pyrimidinderivat med avsoendring av urinsyra i urin utoekande
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3960860A (en) 1973-01-08 1976-06-01 International Flavors & Fragrances Inc. 2-Methyl-5,7-dihydrothieno-[3,4d]-pyrimidine
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
GB1570494A (en) 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
ZA782648B (en) 1977-05-23 1979-06-27 Ici Australia Ltd The prevention,control or eradication of infestations of ixodid ticks
IE51802B1 (en) 1979-12-03 1987-04-01 Fujisawa Pharmaceutical Co Quinazoline derivatives,processes for their preparation and pharmaceutical compositions containing them
GB8504253D0 (en) 1985-02-19 1985-03-20 Ici Plc Electrostatic spraying apparatus
US4960870A (en) 1987-02-11 1990-10-02 Ciba-Geigy Corporation Heavy metal complex azo dyes containing a benzothiophene-1,1-dioxide, 2,1-benzothiazine-2,2-dioxide, 1,4-benzothiazine-1,1-dioxide or thienopyridine-1,1-dioxide coupling component
US5380541A (en) 1987-08-07 1995-01-10 Tate & Lyle Public Limited Company Sucralose compositions
DE3815221C2 (de) 1988-05-04 1995-06-29 Gradinger F Hermes Pharma Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen
JPH02238856A (ja) * 1989-03-14 1990-09-21 Mitajiri Kagaku Kogyo Kk ミラクリンを有効成分とする矯味・調味料及びこれを含有する飲食品
US5504095A (en) 1990-09-19 1996-04-02 Pfizer Inc. Aminobenzosultam derivatives as lipoxygenase inhibitors
US5698155A (en) 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
IL102764A0 (en) 1991-08-16 1993-01-31 Merck & Co Inc Quinazoline derivatives,and pharmaceutical compositions containing them
GB9127188D0 (en) 1991-12-21 1992-02-19 Smithkline Beecham Plc Novel compounds
IL117473A (en) 1995-03-14 2001-08-26 Siemens Ag Ultrasonic atomizer device with removable precision dosating unit
EP0814861B1 (en) 1995-03-14 2002-06-05 Siemens Aktiengesellschaft Ultrasonic atomizer device with removable precision dosing unit
BR9714426A (pt) * 1996-12-20 2000-04-25 Nutrinova Gmbh Processo para reforçar a intensidade adoçante e para aperfeiçoar o sabor de uma mistura de adoçantes altamente intensos
US5954047A (en) 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
JP3523166B2 (ja) 1999-09-02 2004-04-26 高砂香料工業株式会社 食品香料劣化防止剤、食品香料劣化防止方法およびその食品香料劣化防止剤を含有する食品
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
CN100447156C (zh) 2000-04-07 2008-12-31 塞诺米克斯公司 T2r味觉受体及其编码基因
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
EP1375487B1 (en) 2001-03-02 2011-08-24 Sumitomo Chemical Company, Limited Process for producing quinoline-3-carboxylic acid compounds
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
EP1412750B1 (en) 2001-06-26 2012-05-23 Senomyx, Inc. T1r2-t1r3 hetero-oligomeric sweet taste receptors and cell lines that express said receptors and use thereof for identification of sweet taste compounds
US7031619B2 (en) * 2001-06-26 2006-04-18 International Business Machines Corporation Method and system for dispersion control of electromagnetic signals in communication networks
DE60208908T8 (de) * 2001-07-19 2008-04-10 San-Ei Gen F.F.I., Inc., Toyonaka Geschmacksverbessernde zusammensetzungen und ihre anwendung
WO2003022214A2 (en) 2001-09-06 2003-03-20 Millennium Pharmaceuticals, Inc. Piperazine and homopiperazine compounds
WO2004012746A2 (en) 2002-08-02 2004-02-12 The Regents Of The University Of California New uses for inhibitors of inosine monophosphate dehydrogenase
DE10324548A1 (de) * 2003-05-28 2004-12-16 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Diätisches Lebensmittel bei einer gewichtskontrollierenden bzw. gewichtsreduzierenden Ernährung
EP1659881B1 (en) 2003-08-06 2019-04-03 Senomyx Inc. Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof
CA2558683A1 (en) * 2004-03-05 2005-09-22 Sunil Srivastava High-intensity sweetener-polyol compositions
US20060045953A1 (en) 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
ES2324231T3 (es) 2004-12-17 2009-08-03 F. Hoffmann-La Roche Ag Derivados de tieno-piridina como intensificadores alostericos de gaba-b.
JP2008530017A (ja) * 2005-02-04 2008-08-07 セノミックス インコーポレイテッド 食料用組成物のための風味調整剤として連結された有機部分を含む分子
TW200715993A (en) 2005-06-15 2007-05-01 Senomyx Inc Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers
JP2007007591A (ja) 2005-07-01 2007-01-18 Mikuni Corp 電解水及びその製造方法
JP5342878B2 (ja) 2005-10-20 2013-11-13 セノミクス・インコーポレーテッド キメラヒト甘味‐旨味および旨味‐甘味味覚受容体
US8633186B2 (en) 2007-06-08 2014-01-21 Senomyx Inc. Modulation of chemosensory receptors and ligands associated therewith
US7928111B2 (en) 2007-06-08 2011-04-19 Senomyx, Inc. Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
EP3085699B1 (en) 2008-07-31 2022-03-02 Firmenich Incorporated Processes for making sweet taste enhancers
ES2753523T3 (es) 2010-04-02 2020-04-13 Firmenich Incorporated Modificador del sabor dulce
CN103153096B (zh) 2010-08-12 2016-08-03 赛诺米克斯公司 提高甜味增强剂的稳定性的方法和包含稳定的甜味增强剂的组合物

Also Published As

Publication number Publication date
US20110195170A1 (en) 2011-08-11
RU2011107248A (ru) 2012-09-10
JP2011529688A (ja) 2011-12-15
MX2011001155A (es) 2011-07-29
JP5723275B2 (ja) 2015-05-27
WO2010014813A2 (en) 2010-02-04
RU2511315C2 (ru) 2014-04-10
CN102170797B (zh) 2014-02-19
EP2328426A2 (en) 2011-06-08
ES2525551T3 (es) 2014-12-26
BRPI0916550B1 (pt) 2020-09-15
HK1159428A1 (en) 2012-08-03
EP2328426B1 (en) 2014-10-01
DK2328426T3 (en) 2014-12-08
CA2732098A1 (en) 2010-02-04
US8609173B2 (en) 2013-12-17
EP2328426A4 (en) 2013-03-13
BRPI0916550A2 (pt) 2019-04-09
WO2010014813A3 (en) 2010-05-06
CN102170797A (zh) 2011-08-31

Similar Documents

Publication Publication Date Title
US8609173B2 (en) Compositions comprising sweetness enhancers and methods of making them
US8754088B2 (en) Sweetner compositions and methods of making them
JP7108601B2 (ja) 液体アルロース組成物
JP2011529688A5 (enExample)
CA2805341C (en) Process for the manufacture of co-crystallized sucrose natural sweeteners and the products thereof
WO2017029244A1 (en) Powdery allulose composition
ES2684399T3 (es) Composición de aroma que contiene glucósidos HMG
JP2004033226A (ja) 甘味料組成物、甘味付与方法およびその利用
HK1159428B (en) Compositions comprising sweetness enhancers and methods of making them
AU2014271347B2 (en) Process for the manufacture of cocrystallized sucrose - polyol natural sweeteners and products thereof
WO2025191050A1 (en) Lipid particles and their comestible use

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140612

MKLA Lapsed

Effective date: 20200831