CA2563074C - Gene expression markers for predicting response to chemotherapy - Google Patents

Gene expression markers for predicting response to chemotherapy Download PDF

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Publication number
CA2563074C
CA2563074C CA2563074A CA2563074A CA2563074C CA 2563074 C CA2563074 C CA 2563074C CA 2563074 A CA2563074 A CA 2563074A CA 2563074 A CA2563074 A CA 2563074A CA 2563074 C CA2563074 C CA 2563074C
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Canada
Prior art keywords
chemotherapy
expression
cancer
rna
genes
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Expired - Lifetime
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CA2563074A
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English (en)
French (fr)
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CA2563074A1 (en
Inventor
Joffre B. Baker
Steven Shak
Luca Gianni
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Fondazione IRCCS Istituto Nazionale dei Tumori
Genomic Health Inc
Original Assignee
Fondazione IRCCS Istituto Nazionale dei Tumori
Genomic Health Inc
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Priority to CA2848463A priority Critical patent/CA2848463A1/en
Publication of CA2563074A1 publication Critical patent/CA2563074A1/en
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Publication of CA2563074C publication Critical patent/CA2563074C/en
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Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2563074A 2004-04-09 2005-04-07 Gene expression markers for predicting response to chemotherapy Expired - Lifetime CA2563074C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2848463A CA2848463A1 (en) 2004-04-09 2005-04-07 Gene expression markers for predicting response to chemotherapy

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56103504P 2004-04-09 2004-04-09
US60/561,035 2004-04-09
PCT/US2005/011760 WO2005100606A2 (en) 2004-04-09 2005-04-07 Gene expression markers for predicting response to chemotherapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2848463A Division CA2848463A1 (en) 2004-04-09 2005-04-07 Gene expression markers for predicting response to chemotherapy

Publications (2)

Publication Number Publication Date
CA2563074A1 CA2563074A1 (en) 2005-10-27
CA2563074C true CA2563074C (en) 2014-05-20

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
CA2563074A Expired - Lifetime CA2563074C (en) 2004-04-09 2005-04-07 Gene expression markers for predicting response to chemotherapy
CA2848463A Abandoned CA2848463A1 (en) 2004-04-09 2005-04-07 Gene expression markers for predicting response to chemotherapy

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2848463A Abandoned CA2848463A1 (en) 2004-04-09 2005-04-07 Gene expression markers for predicting response to chemotherapy

Country Status (9)

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US (2) US7871769B2 (enExample)
EP (4) EP2947160B1 (enExample)
JP (3) JP5813908B2 (enExample)
AU (2) AU2005233593B2 (enExample)
CA (2) CA2563074C (enExample)
DK (1) DK2163650T3 (enExample)
ES (2) ES2636470T3 (enExample)
IL (4) IL178508A (enExample)
WO (1) WO2005100606A2 (enExample)

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