CA2514471C - Composite materials comprising supported porous gels - Google Patents

Composite materials comprising supported porous gels Download PDF

Info

Publication number
CA2514471C
CA2514471C CA2514471A CA2514471A CA2514471C CA 2514471 C CA2514471 C CA 2514471C CA 2514471 A CA2514471 A CA 2514471A CA 2514471 A CA2514471 A CA 2514471A CA 2514471 C CA2514471 C CA 2514471C
Authority
CA
Canada
Prior art keywords
composite material
poly
cross
gel
macroporous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2514471A
Other languages
English (en)
French (fr)
Other versions
CA2514471A1 (en
Inventor
Ronald F. Childs
Carlos Filipe
Raja Ghosh
Alicja M. Mika
Jinsheng Zhou
Elena N. Komkova
Marcus Kim
Tapan K. Dey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Millipore Ltd
Original Assignee
Natrix Separations Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32908490&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2514471(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Natrix Separations Inc filed Critical Natrix Separations Inc
Publication of CA2514471A1 publication Critical patent/CA2514471A1/en
Application granted granted Critical
Publication of CA2514471C publication Critical patent/CA2514471C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0002—Organic membrane manufacture
    • B01D67/0006—Organic membrane manufacture by chemical reactions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/10—Supported membranes; Membrane supports
    • B01D69/106—Membranes in the pores of a support, e.g. polymerized in the pores or voids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/10—Supported membranes; Membrane supports
    • B01D69/107—Organic support material
    • B01D69/1071—Woven, non-woven or net mesh
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/40—Polymers of unsaturated acids or derivatives thereof, e.g. salts, amides, imides, nitriles, anhydrides, esters
    • B01D71/401—Polymers based on the polymerisation of acrylic acid, e.g. polyacrylate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/261—Synthetic macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/262—Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/264—Synthetic macromolecular compounds derived from different types of monomers, e.g. linear or branched copolymers, block copolymers, graft copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B01J20/267—Cross-linked polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28011—Other properties, e.g. density, crush strength
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28023—Fibres or filaments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28033—Membrane, sheet, cloth, pad, lamellar or mat
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28047—Gels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28069—Pore volume, e.g. total pore volume, mesopore volume, micropore volume
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B01J20/28085—Pore diameter being more than 50 nm, i.e. macropores
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28095—Shape or type of pores, voids, channels, ducts
    • B01J20/28097—Shape or type of pores, voids, channels, ducts being coated, filled or plugged with specific compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/291—Gel sorbents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/305—Addition of material, later completely removed, e.g. as result of heat treatment, leaching or washing, e.g. for forming pores
    • B01J20/3064—Addition of pore forming agents, e.g. pore inducing or porogenic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3276—Copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3278—Polymers being grafted on the carrier
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B01J20/3282—Crosslinked polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/20—Anion exchangers for chromatographic processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J47/00—Ion-exchange processes in general; Apparatus therefor
    • B01J47/018—Granulation; Incorporation of ion-exchangers in a matrix; Mixing with inert materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J47/00—Ion-exchange processes in general; Apparatus therefor
    • B01J47/12—Ion-exchange processes in general; Apparatus therefor characterised by the use of ion-exchange material in the form of ribbons, filaments, fibres or sheets, e.g. membranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34—Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/30—Cross-linking
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/34—Use of radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/12—Adsorbents being present on the surface of the membranes or in the pores
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/14—Membrane materials having negatively charged functional groups
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/16—Membrane materials having positively charged functional groups
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/38—Hydrophobic membranes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/249921—Web or sheet containing structurally defined element or component
    • Y10T428/249953—Composite having voids in a component [e.g., porous, cellular, etc.]
    • Y10T428/249978—Voids specified as micro
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/249921—Web or sheet containing structurally defined element or component
    • Y10T428/249994—Composite having a component wherein a constituent is liquid or is contained within preformed walls [e.g., impregnant-filled, previously void containing component, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Water Supply & Treatment (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Nanotechnology (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Materials For Medical Uses (AREA)
  • Nonwoven Fabrics (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Peptides Or Proteins (AREA)
  • Polymerisation Methods In General (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
CA2514471A 2003-02-19 2004-01-29 Composite materials comprising supported porous gels Expired - Lifetime CA2514471C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44773003P 2003-02-19 2003-02-19
US60/447,730 2003-02-19
PCT/CA2004/000120 WO2004073843A1 (en) 2003-02-19 2004-01-29 Composite materials comprising supported porous gels

Publications (2)

Publication Number Publication Date
CA2514471A1 CA2514471A1 (en) 2004-09-02
CA2514471C true CA2514471C (en) 2013-09-10

Family

ID=32908490

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2514471A Expired - Lifetime CA2514471C (en) 2003-02-19 2004-01-29 Composite materials comprising supported porous gels

Country Status (9)

Country Link
US (9) US7316919B2 (enExample)
EP (3) EP2143481A1 (enExample)
JP (2) JP5189286B2 (enExample)
KR (1) KR101113201B1 (enExample)
AT (1) ATE448866T1 (enExample)
AU (2) AU2004212641B2 (enExample)
CA (1) CA2514471C (enExample)
DE (1) DE602004024190D1 (enExample)
WO (1) WO2004073843A1 (enExample)

Families Citing this family (221)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030008396A1 (en) * 1999-03-17 2003-01-09 Ku David N. Poly(vinyl alcohol) hydrogel
DE602004024190D1 (de) 2003-02-19 2009-12-31 Natrix Separations Inc Geträgerte poröse gele umfassende verbundmaterialien
US20070082019A1 (en) * 2003-02-21 2007-04-12 Ciphergen Biosystems Inc. Photocrosslinked hydrogel surface coatings
JP2007525571A (ja) 2004-01-07 2007-09-06 ソレクサ リミテッド 修飾分子アレイ
US7479222B2 (en) 2004-02-05 2009-01-20 Millipore Corporation Porous adsorptive or chromatographic media
CA2558661C (en) 2004-02-06 2012-09-04 Georgia Tech Research Corporation Load bearing biocompatible device
EP1786485A4 (en) * 2004-02-06 2012-05-30 Georgia Tech Res Inst CELLULAR IMPLANTATION WITH SURFACE ADHESION
CA2558859C (en) 2004-04-08 2014-02-04 Mcmaster University Membrane stacks
US7604746B2 (en) * 2004-04-27 2009-10-20 Mcmaster University Pervaporation composite membranes
EP1773485B1 (en) * 2004-06-07 2015-09-16 Natrix Separations Inc. Stable composite material comprising supported porous gels
US20050278025A1 (en) * 2004-06-10 2005-12-15 Salumedica Llc Meniscus prosthesis
US7147912B2 (en) * 2004-08-18 2006-12-12 E. I. Du Pont De Nemours And Company Amphipathic proteinaceous coating on nanoporous polymer
CN104133060B (zh) 2004-09-23 2016-06-29 三路影像公司 分析生物样品的方法
US7590444B2 (en) 2004-12-09 2009-09-15 Tti Ellebeau, Inc. Iontophoresis device
JP4731931B2 (ja) 2005-02-03 2011-07-27 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
JP4793806B2 (ja) 2005-03-22 2011-10-12 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
EP1861259B1 (en) * 2005-03-23 2009-01-07 FUJIFILM Manufacturing Europe B.V. Method of making microporous membranes and image recording materials comprising the same
BRPI0608100A2 (pt) * 2005-04-22 2009-11-03 Dsm Ip Assets Bv materiais poliméricos altamente porosos compreendendo moléculas biologicamente ativas através de enxerto covalente
US7311825B2 (en) * 2005-05-02 2007-12-25 Varian, Inc. Polymer modified porous substrate for solid phase extraction
US20060247361A1 (en) * 2005-05-02 2006-11-02 Varian, Inc. Polar functionalized polymer modified porous substrate for solid phase extraction
WO2006127973A2 (en) * 2005-05-24 2006-11-30 Waters Inverstments Limited Methods for separating and analyzing anionic compounds
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
KR101325856B1 (ko) 2005-09-30 2013-11-05 닛산 가가쿠 고교 가부시키 가이샤 감열 응답성 고분자를 이용한 구멍 패턴 첨부막을 가지는칩 및 그 제조 방법
JP5203563B2 (ja) * 2005-11-08 2013-06-05 株式会社東芝 膜ろ過システム
US20070125700A1 (en) * 2005-12-05 2007-06-07 Jiang Ding Nanoweb composite material and gelling method for preparing same
US8268395B2 (en) * 2005-12-05 2012-09-18 E. I. Du Pont De Nemours And Company Method for providing resistance to biofouling in a porous support
WO2007079193A2 (en) 2005-12-30 2007-07-12 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
EP1968792B1 (en) * 2005-12-30 2013-12-11 3M Innovative Properties Company Functionalized substrates
KR20090003208A (ko) * 2006-03-20 2009-01-09 가부시끼가이샤 제이엠에스 다공질 생체 흡수성 재료 및 그의 제조방법
JP5083934B2 (ja) * 2006-06-08 2012-11-28 株式会社リバース・プロテオミクス研究所 アフィニティ担体及びその製造方法
EP2043767B1 (en) 2006-07-14 2020-03-25 Wisconsin Alumni Research Foundation Adsorptive membranes for trapping viruses
JP4815599B2 (ja) * 2006-08-04 2011-11-16 国立大学法人 千葉大学 メソ細孔性ポリマーの製造方法及びその製造装置
US7678716B2 (en) * 2006-08-31 2010-03-16 Kimberly-Clark Worldwide, Inc. Hydrogel-web composites for thermal energy transfer applications and methods of making the same
US20080057811A1 (en) * 2006-08-31 2008-03-06 Kimberly-Clark Worldwide, Inc. Multifunctional hydrogel-web composites for enhanced absorbency applications and methods of making the same
US7473658B2 (en) * 2006-11-13 2009-01-06 E. I. Du Pont Nemours And Company Partially fluorinated amino acid derivatives as gelling and surface active agents
EP2091623A4 (en) * 2006-11-17 2011-10-12 Gareth Michael Forde MATERIALS, METHODS AND SYSTEMS FOR PURIFICATION AND / OR SEPARATION OF MOLECULES
WO2008087803A1 (ja) * 2007-01-16 2008-07-24 Hokkaido University 抗酸化成分を封入したイオントフォレーシス用リポソーム製剤
US20080176768A1 (en) * 2007-01-23 2008-07-24 Honeywell Honeywell International Hydrogel microarray with embedded metal nanoparticles
EP1967644A1 (en) * 2007-03-07 2008-09-10 Jacobs University Bremen gGmbH Composite microfibre
US7553886B2 (en) * 2007-04-23 2009-06-30 Hewlett-Packard Development Company, L.P. Cross-linked latex particulates
US9433922B2 (en) 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
US20090098359A1 (en) 2007-10-11 2009-04-16 Waller Jr Clinton P Hydrophilic porous substrates
US20090123519A1 (en) * 2007-11-12 2009-05-14 Surmodics, Inc. Swellable hydrogel matrix and methods
US8389290B2 (en) * 2007-11-30 2013-03-05 Becton, Dickinson And Company Biosensor device for sensing amphipathic analytes
US8241697B2 (en) 2007-12-20 2012-08-14 Abbott Point Of Care Inc. Formation of immobilized biological layers for sensing
US8268604B2 (en) * 2007-12-20 2012-09-18 Abbott Point Of Care Inc. Compositions for forming immobilized biological layers for sensing
SG188098A1 (en) 2008-01-30 2013-03-28 Geron Corp Synthetic surfaces for culturing stem cell derived cardiomyocytes
WO2009146321A1 (en) 2008-05-30 2009-12-03 3M Innovative Properties Company Ligand functionalized substrates
EP2522692B1 (en) 2008-05-30 2014-06-18 3M Innovative Properties Company Ligand monomers and copolymers made therewith
GB0813227D0 (en) * 2008-07-18 2008-08-27 Fuji Film Mfg Europ B V Process for preparing membranes
EP2153877A1 (de) * 2008-07-30 2010-02-17 MERCK PATENT GmbH Mischpfropfpolymere für die Ionenaustauschchromatographie
US20100055188A1 (en) * 2008-08-28 2010-03-04 Dong June Ahn Nano-valves for small-molecule drug delivery
JP5767584B2 (ja) 2008-09-02 2015-08-19 ナトリックス セパレイションズ インコーポレーテッド クロマトグラフィー膜、それを含む装置及びその使用方法
JP5711127B2 (ja) 2008-09-19 2015-04-30 スリーエム イノベイティブ プロパティズ カンパニー リガンドグラフト官能化基材
WO2010039384A2 (en) * 2008-09-30 2010-04-08 Fresenius Medical Care Holdings, Inc. Covalently immobilized enzyme and method to make the same
BRPI0923565A2 (pt) * 2008-12-23 2016-01-26 3M Innovative Properties Co artigo não tecido funcionalizado
KR20110110265A (ko) 2008-12-29 2011-10-06 신세스 게엠바하 수술 부위의 보존을 위한 막 조성물의 형성 방법 및 결과적으로 얻어진 막조성물
KR101782624B1 (ko) * 2010-02-12 2017-09-28 삼성전자주식회사 에어로젤 및 에어로젤의 제조방법
KR101666098B1 (ko) 2010-04-01 2016-10-14 삼성전자 주식회사 에어로젤, 에어로젤용 조성물 및 에어로젤의 제조방법
KR101627127B1 (ko) * 2009-09-24 2016-06-03 삼성전자 주식회사 유기 에어로젤 및 유기 에어로젤용 조성물
KR101660316B1 (ko) 2010-03-30 2016-09-28 삼성전자 주식회사 유기 에어로젤 및 유기 에어로젤용 조성물
KR101560738B1 (ko) * 2009-02-11 2015-10-16 삼성전자 주식회사 유기 에어로젤, 이의 형성용 조성물 및 이의 제조방법
US8691883B2 (en) 2009-02-11 2014-04-08 Samsung Electronics Co., Ltd. Aerogel-foam composites
KR20110049572A (ko) * 2009-11-05 2011-05-12 삼성전자주식회사 유기 에어로젤, 유기 에어로젤용 조성물 및 상기 유기 에어로젤의 제조 방법
US20100210160A1 (en) * 2009-02-18 2010-08-19 3M Innovative Properties Company Hydrophilic porous substrates
US20100209693A1 (en) * 2009-02-18 2010-08-19 3M Innovative Properties Company Hydrophilic porous substrates
EP2398577A2 (en) 2009-02-19 2011-12-28 Bonner, Alex Garfield Porous interpenetrating polymer network
JP6141597B2 (ja) * 2009-02-27 2017-06-07 イー・エム・デイー・ミリポア・コーポレイシヨン タンパク質凝集物を除去するためのスルホン基を含有する膜
GB0904560D0 (en) * 2009-03-17 2009-04-29 Fujifilm Mfg Europe Bv Process for preparing composite membranes
GB0904558D0 (en) 2009-03-17 2009-04-29 Fujifilm Mfg Europe Bv Membranes
US8192635B2 (en) * 2009-04-20 2012-06-05 Dholakia Jayant M Method for reducing clogging of filters
BRPI1011747A2 (pt) 2009-06-23 2018-02-27 3M Innovative Properties Co artigo não tecido funcionalizado.
JP5948243B2 (ja) 2009-08-26 2016-07-06 エヴォクア ウォーター テクノロジーズ ピーティーイー リミテッド イオン交換膜
WO2011060088A1 (en) * 2009-11-10 2011-05-19 Porous Media Corporation Gel-filled membrane device and method
EP2499192B1 (en) * 2009-11-13 2020-07-15 Merck Millipore Ltd. Hydrophobic interaction chromatography membranes
US8353410B2 (en) * 2009-11-24 2013-01-15 International Business Machines Corporation Polymeric films made from polyhedral oligomeric silsesquioxane (POSS) and a hydrophilic comonomer
US8011517B2 (en) * 2009-11-24 2011-09-06 International Business Machines Corporation Composite membranes with performance enhancing layers
JP6184695B2 (ja) * 2009-12-04 2017-08-23 ジェネンテック， インコーポレイテッド 多重特異性抗体、抗体アナログ、組成物、及び方法
US8277649B2 (en) * 2009-12-14 2012-10-02 General Electric Company Membranes and associated methods for purification of antibodies
GB0921951D0 (en) 2009-12-16 2010-02-03 Fujifilm Mfg Europe Bv Curable compositions and membranes
GB0921949D0 (en) * 2009-12-16 2010-02-03 Fujifilm Mfg Europe Bv Curable compositions and membranes
US8377672B2 (en) 2010-02-18 2013-02-19 3M Innovative Properties Company Ligand functionalized polymers
EP2889625B1 (en) 2010-03-03 2016-09-14 3M Innovative Properties Company Ligand guanidinyl functionalized polymers
EP2368925B1 (en) * 2010-03-27 2016-05-11 Samsung Electronics Co., Ltd. Aerogel, composition for the aerogel, and method of making the aerogel
WO2011120691A1 (en) 2010-04-01 2011-10-06 Roche Diagnostics Gmbh Method for isolating an analyte from a sample fluid with a protein-repellent hydrogel
GB201007556D0 (en) 2010-05-06 2010-06-23 Wetenschappelijk En Tech Ct Va Methods and compositions for textile layers and coatings
US10189773B2 (en) 2010-05-07 2019-01-29 Medicus Biosciences, Llc In-vivo gelling pharmaceutical pre-formulation
WO2011150935A1 (en) * 2010-06-01 2011-12-08 Coloplast A/S Gels from polystyrene-based photoinitiators
WO2011153085A2 (en) * 2010-06-01 2011-12-08 3M Innovative Properties Company Process for making coated porous materials
WO2011152967A2 (en) * 2010-06-01 2011-12-08 3M Innovative Properties Company Coated porous materials
WO2012037101A2 (en) * 2010-09-14 2012-03-22 Natrix Separations Inc. Chromatography membranes for the purification of chiral compounds
WO2012037322A2 (en) 2010-09-15 2012-03-22 Jeld-Wen, Inc. Anti-bonding coatings for inhibiting material adhesion to equipment in thin-layer fiber composite manufacturing
CA2844706C (en) * 2010-10-04 2014-09-16 Saltworks Technologies Inc. Resilient anion exchange membranes
AU2011315854B2 (en) 2010-10-15 2015-04-09 Evoqua Water Technologies Llc Process for making a monomer solution for making cation exchange membranes
CA2814699C (en) 2010-10-15 2019-08-06 Siemens Industry, Inc. Anion exchange membranes and process for making
CN102000511A (zh) * 2010-12-07 2011-04-06 天津工业大学 一种表面紫外辐照接枝制备荷正电中空纤维纳滤膜的方法
WO2012091965A1 (en) 2010-12-17 2012-07-05 Carnegie Mellon University Electrochemically mediated atom transfer radical polymerization
WO2012081727A1 (ja) * 2010-12-17 2012-06-21 旭化成メディカル株式会社 強カチオン交換基を有する温度応答性吸着剤、及びその製造方法
US20130306545A1 (en) 2010-12-27 2013-11-21 Asahi Kasei Chemicals Corporation Adsorption/separation membrane module, method for producing adsorption/separation membrane module, and partition member
CN103403073B (zh) * 2011-02-03 2015-10-14 3M创新有限公司 硬涂膜
JP2014508640A (ja) 2011-02-16 2014-04-10 ダウ コーニング コーポレーション 多孔質基材のコーティング方法
CN103563027B (zh) * 2011-03-23 2018-09-21 梅斯皮鲁斯股份有限公司 用于流过式电容性去电离的极化电极
JP5367758B2 (ja) * 2011-05-02 2013-12-11 株式会社東芝 温度応答性膜を用いた膜ろ過システム
EP2705361A4 (en) * 2011-05-03 2015-01-28 Avantor Performance Mat Inc NEW CHROMATOGRAPHY MEDIA ON ALLYLAMINE BASE AND DERIVATIVES THEREOF FOR PROTEIN CLEANING
WO2012158896A2 (en) * 2011-05-17 2012-11-22 Natrix Separations Inc. Layered tubular membranes for chromatography, and methods of use thereof
EP2757964B1 (en) 2011-05-26 2016-05-04 Cartiva, Inc. Tapered joint implant and related tools
US8895104B2 (en) 2011-07-01 2014-11-25 International Business Machines Corporation Thin film composite membranes embedded with molecular cage compounds
EP2545989A1 (en) 2011-07-13 2013-01-16 InstrAction GmbH Composite material for chromatographic applications
US11083821B2 (en) 2011-08-10 2021-08-10 C.P. Medical Corporation Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules
US10111985B2 (en) * 2011-08-10 2018-10-30 Medicus Biosciences, Llc Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules
US20140275420A1 (en) 2011-08-22 2014-09-18 Carnegie Mellon University Atom transfer radical polymerization under biologically compatible conditions
JP5916006B2 (ja) * 2011-09-21 2016-05-11 日立化成株式会社 液体クロマトグラフィー用カラム及びその製造方法
TWI457165B (zh) 2011-09-30 2014-10-21 Asahi Kasei Chemicals Corp Purification of proteins
EP2793021A4 (en) 2011-12-15 2015-08-19 Asahi Kasei Chemicals Corp PROTEINADSORBENS
CA2861932C (en) 2012-01-19 2021-09-14 Natrix Separations Inc. Chromatographic media for storage and delivery of therapeutic biologics and small molecules
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
CA2863060C (en) * 2012-04-19 2015-08-18 Saltworks Technologies Inc. Resilient cation exchange membranes prepared by polymerizing ionic surfactant monomers
US20130284669A1 (en) * 2012-04-25 2013-10-31 Millipore Corporation Negatively charged porous medium for removing protein aggregates
US8974578B2 (en) * 2012-05-07 2015-03-10 Northwestern University Porous polymer networks and ion-exchange media and metal-polymer composites made therefrom
EP2846847B1 (en) 2012-05-11 2020-03-25 C.P. Medical Corporation Biocompatible hydrogel treatments for retinal detachment
US10350072B2 (en) 2012-05-24 2019-07-16 Cartiva, Inc. Tooling for creating tapered opening in tissue and related methods
US9012022B2 (en) 2012-06-08 2015-04-21 Illumina, Inc. Polymer coatings
KR102133611B1 (ko) * 2012-06-14 2020-07-13 마이크로벤션, 인코포레이티드 중합체 치료 조성물
BR112015005937A2 (pt) 2012-09-17 2017-07-04 Grace W R & Co meios e dispositivos cromatográficos
EP2903737B1 (en) 2012-10-04 2022-05-04 Evoqua Water Technologies LLC High-performance anion exchange membranes and methods of making same
SG11201502697YA (en) 2012-10-11 2015-05-28 Evoqua Water Technologies Llc Coated ion exchange membranes
WO2014062696A1 (en) 2012-10-15 2014-04-24 Microvention, Inc. Polymeric treatment compositions
CN104822654B (zh) 2012-10-19 2017-10-20 苏特沃克技术有限公司 丙烯酰胺基交联单体，它们的制备和应用
KR101515446B1 (ko) 2012-11-15 2015-05-11 중앙대학교 산학협력단 멤브레인 복합체 이를 이용한 멤브레인 모듈 및 수처리 방법
EP4089101A1 (en) * 2013-02-26 2022-11-16 Merck Millipore Ltd Mixed-mode chromatography membranes
US20140273158A1 (en) * 2013-03-14 2014-09-18 Natrix Separations Inc. Chromatography Membranes Stable Under Caustic Conditions
JP6163541B2 (ja) * 2013-04-16 2017-07-12 旭化成メディカル株式会社 抗体タンパク質の精製方法
EP3021114B1 (en) * 2013-07-08 2021-03-03 National University Corporation Kyoto Institute of Technology Separating agent
CN103523882B (zh) * 2013-10-18 2016-03-30 中国海洋石油总公司 一种复合型絮凝剂
JP5825612B2 (ja) * 2013-11-14 2015-12-02 学校法人兵庫医科大学 新規固相担体
WO2015077771A1 (en) * 2013-11-25 2015-05-28 Carnegie Mellon University Ordered macroporous hydrogels for bioresponsive processes
EP2881163A1 (en) * 2013-12-05 2015-06-10 Gambro Lundia AB Composite membrane
CN110054661A (zh) 2013-12-12 2019-07-26 Emd密理博公司 使用含丙烯酰胺的过滤器分离蛋白
ES2887110T3 (es) 2014-01-16 2021-12-21 Grace W R & Co Medios para cromatografía de afinidad y dispositivos para cromatografía
US9731249B2 (en) * 2014-04-15 2017-08-15 Ut-Battelle, Llc Polymeric molecular sieve membranes for gas separation
CN105013453B (zh) * 2014-04-17 2017-08-25 宁波大学 一种可用于提取溶菌酶的阴离子骨架聚合物及其制备方法
CN105013452B (zh) * 2014-04-17 2017-08-22 宁波大学 一种能吸收空气中甲醛的高分子骨架材料及其制备方法
CN104998622B (zh) * 2014-04-17 2017-10-20 宁波大学 一种能清除空气中细菌的阳离子化骨架聚合物及其制备方法
US11389783B2 (en) 2014-05-02 2022-07-19 W.R. Grace & Co.-Conn. Functionalized support material and methods of making and using functionalized support material
US10852272B2 (en) * 2014-06-05 2020-12-01 The Regents Of The University Of California Devices and methods using pore size modulation for detecting analytes in a fluid sample
CN106574915B (zh) 2014-07-25 2019-10-11 旭化成医疗株式会社 阳离子交换色谱载体及其使用方法
US9469737B2 (en) 2014-08-20 2016-10-18 Pall Corporation Robust polymeric membrane
CA3003397A1 (en) 2014-10-30 2016-05-06 Textile-Based Delivery, Inc. Delivery systems
CN104475064B (zh) * 2014-12-16 2016-06-08 湖南科技大学 用于重金属复杂阴离子的吸附材料及其制备方法
US9982070B2 (en) 2015-01-12 2018-05-29 Carnegie Mellon University Aqueous ATRP in the presence of an activator regenerator
EP3778001A1 (en) * 2015-02-20 2021-02-17 Merck Millipore Ltd. Chromatography membranes formed by thiol-ene or thiol-yne click polymerization reactions
US11198103B2 (en) * 2015-03-10 2021-12-14 Trustees Of Tufts College Two-layer nanofiltration membranes
AU2016233336B2 (en) 2015-03-16 2019-08-29 3M Innovative Properties Company Coalescing elements in copper production
AU2016243659B2 (en) 2015-03-31 2020-04-23 Cartiva, Inc. Hydrogel implants with porous materials and methods
WO2016161026A1 (en) 2015-03-31 2016-10-06 Cartiva, Inc. Carpometacarpal (cmc) implants and methods
PL3302784T3 (pl) 2015-06-05 2022-01-17 W.R. Grace & Co.-Conn. Adsorbentowe środki klarujące do bioprzetwarzania oraz sposoby ich wytwarzania i stosowania
KR20180019756A (ko) * 2015-07-13 2018-02-26 도쿄엘렉트론가부시키가이샤 다공성 재료를 코팅 또는 충전하는 방법
GB201515602D0 (en) * 2015-09-03 2015-10-21 Biocompatibles Uk Ltd Polymers and microspheres
US11065601B2 (en) 2015-12-18 2021-07-20 University Of Canterbury Separation medium
US10115586B2 (en) 2016-05-08 2018-10-30 Tokyo Electron Limited Method for depositing a planarization layer using polymerization chemical vapor deposition
US10368874B2 (en) 2016-08-26 2019-08-06 Microvention, Inc. Embolic compositions
WO2018050849A1 (en) 2016-09-15 2018-03-22 Klawego Gmbh & Co. Kg The use of a polymeric mesh for the purification of macromolecules
CN106758164A (zh) * 2016-11-22 2017-05-31 郑州仁宏医药科技有限公司 一种烟气过滤材料后整理用发泡材料及其制备方法和应用
KR101952288B1 (ko) * 2016-12-19 2019-05-17 예일 유니버시티 자가 복원이 가능한 하이드로겔 충진 수처리용 분리막의 제조방법
US11174325B2 (en) 2017-01-12 2021-11-16 Carnegie Mellon University Surfactant assisted formation of a catalyst complex for emulsion atom transfer radical polymerization processes
DE102017000631A1 (de) 2017-01-24 2018-07-26 Sartorius Stedim Biotech Gmbh Chromatographiemedium mit gebundenen Mikroglobuli und Verfahren zu dessen Herstellung
DE202017007538U1 (de) 2017-01-24 2022-08-19 Sartorius Stedim Biotech Gmbh Chromatographiemedium mit gebundenen Mikroglobuli
EP3592787A4 (en) * 2017-03-10 2021-01-20 University of Florida Research Foundation MICROGEL PARTICLES FOR USE IN 3D PRINTING AND 3D CELL GROWTH MEDIA AND ASSOCIATED COMPOSITIONS, SYSTEMS AND PROCESSES
CN106925141B (zh) * 2017-03-27 2019-06-07 大连理工大学 一种隔氧光引发水凝胶复合膜的制备方法
EP3655139A1 (en) * 2017-07-17 2020-05-27 Boehringer Ingelheim Vetmedica GmbH Modified filter membrane and the use thereof
WO2019074965A1 (en) 2017-10-09 2019-04-18 Microvention, Inc. EMBOLIC RADIOACTIVE LIQUID
EP3476464B1 (en) * 2017-10-31 2025-05-07 Tokyo Ohka Kogyo Co., Ltd. Surface treatment method, use of liquids in surface treatment, and surface-treated article
WO2019170634A1 (en) 2018-03-05 2019-09-12 Chiral Technologies Europe Sas Composite material for bioseparations
WO2019170635A1 (en) 2018-03-05 2019-09-12 Chiral Technologies Europe Sas Composite material for bioseparations
US12485364B2 (en) 2018-08-10 2025-12-02 Clemson University Research Foundation Multi-modal ion-exchange membranes for rapid separations
US10737259B2 (en) 2018-08-31 2020-08-11 Pall Corporation Salt tolerant anion exchange medium
US11045773B2 (en) * 2018-08-31 2021-06-29 Pall Corporation Salt tolerant porous medium
GB201815407D0 (en) * 2018-09-21 2018-11-07 Fujifilm Mfg Europe Bv Membranes suitable for detecting, filtering and/or purifying biomolecules and metal-ions
GB201815405D0 (en) * 2018-09-21 2018-11-07 Fujifilm Mfg Europe Bv Membranes suitable for detecting, filtering and/or purifying biomolecules
US20220062828A1 (en) 2018-09-25 2022-03-03 Evoqua Water Technolgies Llc Monovalent Selective Cation Exchange Membrane
US12154702B1 (en) 2018-10-15 2024-11-26 Ampcera Inc. Methods for manufacturing a freestanding solid state ionic conductive membrane
US11819806B1 (en) 2018-10-15 2023-11-21 Ampcera Inc. Methods for manufacturing a solid state ionic conductive membrane on a macro porous support scaffold
US11177498B1 (en) 2018-10-15 2021-11-16 Ampcera Inc. Redox flow batteries, components for redox flow batteries and methods for manufacture thereof
CN109675448A (zh) * 2018-10-26 2019-04-26 浙江工业大学 一种防污阴离子交换膜的制备方法
KR102158168B1 (ko) * 2018-10-30 2020-09-21 이화여자대학교 산학협력단 가지형 가교제를 포함하는 voc 흡수 및 제거용 소수성 겔 및 제조방법
CN109535314B (zh) * 2018-11-23 2022-03-11 浙江工业大学 一种疏水性纳凝胶及其制备方法
WO2020123714A1 (en) 2018-12-12 2020-06-18 Purilogics, LLC Affinity membrane and method of preparation
CA3130894A1 (en) 2019-02-20 2020-08-27 Emd Millipore Corporation Device for bind and elute chromatography using membranes, and method of manufacture
US11600853B1 (en) 2019-05-14 2023-03-07 Ampcera Inc. Systems and methods for storing, transporting, and handling of solid-state electrolytes
US20220341664A1 (en) 2019-09-13 2022-10-27 Merck Millipore Ltd. Supercritical drying of chromatographic media
TWI786468B (zh) * 2019-11-21 2022-12-11 愛爾蘭商默克密理博有限公司 將配體偶合至複合材料的方法
KR102366793B1 (ko) * 2019-12-24 2022-02-23 이화여자대학교 산학협력단 휘발성 유기화합물 흡수 및 제거용 스펀지형 친지성 겔의 제조 방법
WO2021222531A1 (en) * 2020-04-29 2021-11-04 Georgia Tech Research Corporation Systems and methods for specimen processing and storage
CN115776917B (zh) * 2020-06-17 2025-04-11 恩特格里斯公司 离子交换膜、过滤器和方法
JP2022018728A (ja) * 2020-07-16 2022-01-27 住友化学株式会社 ガス分離膜用の樹脂組成物及びガス分離膜
EP4019125A1 (en) 2020-12-22 2022-06-29 Sartorius Stedim Biotech GmbH Chromatographic material and method of producing same
DE102020216579B4 (de) 2020-12-28 2022-08-18 Cellcopedia GmbH Vorrichtung und Verfahren zur Separation von Partikeln in einer Flüssigkeit, Kit enthaltend die Vorrichtung und Verwendungen der Vorrichtung
KR102240245B1 (ko) * 2021-01-07 2021-04-13 김종덕 소변 냄새 방지 기능을 강화한 반려동물용 수세식 배변판
US11879043B2 (en) * 2021-04-05 2024-01-23 Dionex Corporation Coated poly-olefins
US20240197963A1 (en) * 2021-04-19 2024-06-20 Northwestern University 3d-printing of strong living scaffolds
CN113318611B (zh) * 2021-05-31 2022-11-11 天津工业大学 具有持久高抗污染性能中空纤维超滤膜及其制备方法
CN113527573B (zh) * 2021-07-23 2023-01-24 苏州双碳新材料有限公司 一种可变机械状态的相变凝胶材料的制备方法
CN113583635B (zh) * 2021-07-23 2023-01-24 苏州双碳新材料有限公司 一种可变机械状态的相变凝胶材料
CA3227947A1 (en) 2021-08-05 2023-02-09 Anja HEINEN-KREUZIG Method for reducing endotoxin levels in nucleic acid purification
KR102567344B1 (ko) * 2021-11-30 2023-08-14 성균관대학교산학협력단 덱스트린 기반 이중 네트워크 고분자 겔 전해질, 이의 제조방법 및 이를 포함하는 에너지 저장 장치
US20230184728A1 (en) * 2021-12-09 2023-06-15 Dionex Corporation Suppressor
CN114524951B (zh) * 2022-01-26 2023-11-21 温州医科大学附属眼视光医院 一种聚多巴胺药物递送载体及其应用
CN115015400B (zh) * 2022-01-28 2024-01-02 河南省人民医院 亲水有机聚合物毛细管电色谱整体柱及其制备方法和应用
KR20240159599A (ko) 2022-03-10 2024-11-05 메르크 파텐트 게엠베하 핵산 정제에서 엔도톡신 수준을 감소시키는 방법
US20250066743A1 (en) 2022-03-18 2025-02-27 Merck Patent Gmbh Methods and compositions for purifying adeno associated virus particles
AR128774A1 (es) 2022-03-18 2024-06-12 Merck Patent Gmbh Métodos y composiciones para purificar pequeñas vesículas extracelulares
CN114933727B (zh) * 2022-06-24 2023-04-07 中国科学院兰州化学物理研究所 一种湿度响应性软硬结合n-异丙基丙烯酰胺离子凝胶复合结构及其制备方法和应用
CN119677574A (zh) 2022-06-24 2025-03-21 默克密理博有限公司 流量分配器和空隙减少装置
CN115160510B (zh) * 2022-07-11 2023-08-29 南京大学 一种增强型吸附树脂材料的制备方法
EP4385618A1 (en) 2022-12-16 2024-06-19 Chiral Technologies Europe SAS Composite material for bioseparations
WO2024141877A1 (en) * 2022-12-28 2024-07-04 Waters Technologies Corporation Immunoaffinity ligands immobilized on porous membranes
WO2024206845A1 (en) * 2023-03-30 2024-10-03 Donaldson Company, Inc. Composite separation media
WO2025027058A1 (en) 2023-08-01 2025-02-06 Merck Patent Gmbh Polishing for aav particles using anion exchange chromatography with improved elution system
WO2025027059A1 (en) 2023-08-02 2025-02-06 Merck Patent Gmbh Method for purification of plasmid dna
EP4606892A1 (en) 2024-02-23 2025-08-27 Merck Patent GmbH Methods for the production of viral particles
EP4650025A1 (en) * 2024-05-16 2025-11-19 Sartorius Stedim Biotech GmbH Integral porous polysaccharide membrane and method of purifying biomolecules using said membrane

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5383A (en) * 1847-12-04 Improvement in decom posing alkaline and other salts
US111992A (en) 1871-02-21 Improvement in seeders
US2779155A (en) * 1953-11-19 1957-01-29 Worthington Corp Turbocharging system for internal combustion engines
US4224415A (en) 1958-07-18 1980-09-23 Rohm And Haas Company Polymerization processes and products therefrom
US3209915A (en) 1962-03-06 1965-10-05 Aircraft Appliances And Equipm Filter
US3417870A (en) 1965-03-22 1968-12-24 Gulf General Atomic Inc Reverse osmosis purification apparatus
GB1149481A (en) 1966-03-30 1969-04-23 Norris Filters Ltd Improvements in or relating to fluid filters
DK142529B (da) 1968-10-25 1980-11-17 Danske Sukkerfab Apparat til adskillelse af væsker i to fraktioner med større, henholdsvis mindre indhold af en given komponent end i udgangsvæsken.
US3520803A (en) 1968-12-24 1970-07-21 Ionics Membrane fluid separation apparatus and process
US3713921A (en) * 1971-04-01 1973-01-30 Gen Electric Geometry control of etched nuclear particle tracks
AU6069773A (en) 1972-10-11 1975-03-27 Commw Scient Ind Res Org Compositions
CH621561A5 (en) * 1974-01-14 1981-02-13 Ceskoslovenska Akademie Ved Process for producing a bromocyan-activated, hydrophilic, polymeric carrier for biologically active compounds in dried form
US3939105A (en) * 1974-06-18 1976-02-17 Union Carbide Corporation Microporous polyurethane hydrogels, method and composites with natural and other synthetic fibers or films
FR2294731A1 (fr) 1974-12-18 1976-07-16 Rhone Poulenc Ind Dispositif de contention pour appareil a membranes semi-permeables
US4108804A (en) * 1975-12-23 1978-08-22 Toru Seita Process for preparation of chromatography solid supports comprising a nucleic acid base-epoxy group containing porous gel
JPS6030291B2 (ja) * 1978-03-20 1985-07-16 森永乳業株式会社 人顆粒球の分化増殖を促進するｈｇｉ糖蛋白質、ｈｇｉ糖蛋白質の製造法及びｈｇｉ糖蛋白質を含有する白血球減少症治療剤
US4170540A (en) * 1978-03-31 1979-10-09 Hooker Chemicals & Plastics Corp. Method for forming microporous membrane materials
US4230697A (en) * 1978-07-03 1980-10-28 Morinaga Milk Industry Co. Ltd. Virus-inactivated HGI-glycoprotein capable of stimulating proliferation and differentiation of human granulocyte, process for preparing same and leukopenia curative containing same
GB2070658B (en) * 1980-03-04 1984-02-29 Boer Mueboer Es Cipoipari Kuta Process for the production of chemically bonded non-woven sheet materials containing a binder of microheteroporous structure
US4473474A (en) * 1980-10-27 1984-09-25 Amf Inc. Charge modified microporous membrane, process for charge modifying said membrane and process for filtration of fluid
US4525527A (en) 1982-01-25 1985-06-25 American Colloid Company Production process for highly water absorbable polymer
CA1200158A (en) 1982-02-05 1986-02-04 Peter J. Degen Surface modified polyamide membrane
CA1226112A (en) 1982-09-09 1987-09-01 Minnesota Mining And Manufacturing Company Microporous sheet material, method of making and articles made therewith
US4601828A (en) * 1983-02-07 1986-07-22 Yale University Transfer of macromolecules from a chromatographic substrate to an immobilizing matrix
US4525374A (en) * 1984-02-27 1985-06-25 Manresa, Inc. Treating hydrophobic filters to render them hydrophilic
JPS61203131A (ja) 1985-03-04 1986-09-09 Agency Of Ind Science & Technol キレート樹脂の製造方法
JPS6214903A (ja) 1985-07-11 1987-01-23 Fuji Photo Film Co Ltd 疎水性の微孔性濾過膜を親水化する方法
JPS6239636A (ja) 1985-08-14 1987-02-20 Mitsubishi Rayon Co Ltd 親水性有機重合体基質の製法
GB8608430D0 (en) 1986-04-07 1986-05-14 Raychem Ltd Porous polymer article
DE3872289T2 (de) 1987-04-03 1993-02-11 Sumitomo Chemical Co Verfahren zur rueckgewinnung von gallium durch chelatharz.
US5059659A (en) * 1987-05-29 1991-10-22 Harry P. Gregor Surface treatments to impart hydrophilicity
JPS6419024A (en) 1987-07-15 1989-01-23 Tosoh Corp Separation of immunoglobulin g subclass
JPH01503808A (ja) 1987-07-16 1989-12-21 イー・アイ・デユポン・ド・ネモアース・アンド・コンパニー（インコーポレイテツド） 固定化された凝集剤を用いるアフイニテイ分離
JPH0687957B2 (ja) 1987-09-11 1994-11-09 日本原子力研究所 複合機能▲ろ▼過膜の製造方法
US5277915A (en) * 1987-10-30 1994-01-11 Fmc Corporation Gel-in-matrix containing a fractured hydrogel
JPH0734861B2 (ja) * 1987-10-30 1995-04-19 エフ・エム・シー・コーポレーション 破砕されたヒドロゲルを内蔵するゲル含有マトリックス
US4889632A (en) 1987-12-10 1989-12-26 Ceskoslovenska Akademie Ved Macroporous polymeric membranes for the separation of polymers and a method of their application
US5268306A (en) 1988-02-29 1993-12-07 Boehringer Mannheim Gmbh Preparation of a solid phase matrix containing a bound specific binding pair
US5114585A (en) * 1988-03-01 1992-05-19 Gelman Sciences, Inc. Charged porous filter
ATE175681T1 (de) 1988-10-17 1999-01-15 Hemasure Inc Verfahren zur kovalenten oberflächen-modifikation hydrophober polymere und erzeugnisse daraus
US5019270A (en) * 1989-07-06 1991-05-28 Perseptive Biosystems, Inc. Perfusive chromatography
US5228989A (en) * 1989-07-06 1993-07-20 Perseptive Biosystems, Inc. Perfusive chromatography
JP2540667B2 (ja) 1989-07-06 1996-10-09 パーセプティブ バイオシステムズ，インコーポレイテッド パ―ヒュ―シブクロマトグラフィ―
US4944879A (en) * 1989-07-27 1990-07-31 Millipore Corporation Membrane having hydrophilic surface
FR2659384B1 (fr) 1990-03-07 1995-09-15 Ungemach Pierre Dispositif de curage et de nettoyage de puits affectes de depots et incrustations.
US5269931A (en) * 1990-09-17 1993-12-14 Gelman Sciences Inc. Cationic charge modified microporous membranes
JPH06505756A (ja) 1990-09-20 1994-06-30 サイマット　リミテッド ポリマー膜
US5160627A (en) 1990-10-17 1992-11-03 Hoechst Celanese Corporation Process for making microporous membranes having gel-filled pores, and separations methods using such membranes
EP0555329B1 (en) 1990-10-30 1996-06-12 Minnesota Mining And Manufacturing Company Articles having a hydrophilic polymeric shell and method for preparing same
US5147541A (en) 1990-11-14 1992-09-15 Koch Membrane Systems, Inc. Spiral filtration module with strengthened membrane leaves and method of constructing same
US5252222A (en) 1990-12-03 1993-10-12 Pall Corporation Filter for parenteral systems and method of using thereof
US5130343A (en) * 1991-03-13 1992-07-14 Cornell Research Foundation, Inc. Process for producing uniform macroporous polymer beads
JPH04292602A (ja) 1991-03-22 1992-10-16 Tokyo Organ Chem Ind Ltd 表面多孔型の架橋共重合体ビーズの製造方法
US5646001A (en) 1991-03-25 1997-07-08 Immunivest Corporation Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population thereof
US5137633A (en) * 1991-06-26 1992-08-11 Millipore Corporation Hydrophobic membrane having hydrophilic and charged surface and process
DE69211010T2 (de) 1991-10-21 1997-01-23 Cornell Res Foundation Inc Chromographiesäule mit makroporöser Polymerfüllung
US5176832A (en) * 1991-10-23 1993-01-05 The Dow Chemical Company Chromatographic separation of sugars using porous gel resins
SE9200827D0 (sv) 1992-03-18 1992-03-18 Pharmacia Lkb Biotech Supet porous polysaccharide gels
US5906734A (en) 1992-06-19 1999-05-25 Biosepra Inc. Passivated porous polymer supports and methods for the preparation and use of same
US5470463A (en) 1992-06-19 1995-11-28 Sepracor Inc. Passivated porous supports and methods for the preparation and use of same
US5445732A (en) 1992-06-19 1995-08-29 Sepracor Inc. Passivated porous polymer supports and methods for the preparation and use of same
MX9303636A (es) * 1992-08-07 1994-07-29 Us Agriculture Composicion y metodo para repeler a las hormigas.
JP3398985B2 (ja) 1992-09-17 2003-04-21 大日本インキ化学工業株式会社 センサーの製造方法
DE4234779A1 (de) 1992-10-15 1994-04-21 Veba Oel Ag Trägerkatalysator und Verwendung desselben
US5316680A (en) 1992-10-21 1994-05-31 Cornell Research Foundation, Inc. Multimodal chromatographic separation media and process for using same
DE69316231T2 (de) 1992-10-21 1998-08-20 Cornell Res Foundation Inc Selektive, die porengrösse betreffende chemische modifikation poröser materialien
US5282971A (en) * 1993-05-11 1994-02-01 Pall Corporation Positively charged polyvinylidene fluoride membrane
US5460720A (en) 1993-08-12 1995-10-24 Schneider; Burnett M. Pleated membrane crossflow fluid separation device
US5403482A (en) 1993-10-12 1995-04-04 Gelman Sciences Inc. Self-supporting, pleated, spirally wound filter and the corresponding process of making
US5728457A (en) * 1994-09-30 1998-03-17 Cornell Research Foundation, Inc. Porous polymeric material with gradients
US5972634A (en) 1994-10-19 1999-10-26 The General Hospital Corporation Diagnostic assay for Alzheimer's disease: assessment of Aβ abnormalities
ATE198079T1 (de) 1995-04-07 2000-12-15 Mogens Havsteen Jakobsen Verfahren zur photochemischen immobilisierung von liganden unter verwendung von chinonen
US5756717A (en) * 1995-05-24 1998-05-26 Perseptive Biosystems, Inc Protein imaging
AU7607096A (en) * 1995-11-09 1997-05-29 University Of Toledo, The Immunoprotective membrane
US6509098B1 (en) 1995-11-17 2003-01-21 Massachusetts Institute Of Technology Poly(ethylene oxide) coated surfaces
JP2000515062A (ja) 1996-07-08 2000-11-14 ユーエスエフ フィルトレイション アンド セパレーションズ グループ インコーポレイテッド カチオン電荷修飾されたメンブレン
US6143174A (en) * 1996-09-05 2000-11-07 Sartorius Ag Filtration unit with pleated filtering elements
US6086769A (en) 1996-09-16 2000-07-11 Commodore Separation Technologies, Inc. Supported liquid membrane separation
US6258276B1 (en) 1996-10-18 2001-07-10 Mcmaster University Microporous membranes and uses thereof
US5929214A (en) * 1997-02-28 1999-07-27 Cornell Research Foundation, Inc. Thermally responsive polymer monoliths
US6271278B1 (en) 1997-05-13 2001-08-07 Purdue Research Foundation Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties
JPH1133370A (ja) 1997-07-22 1999-02-09 Yuasa Corp 浸漬型膜エレメント
DE19739218A1 (de) 1997-09-08 1999-03-11 Boehringer Mannheim Gmbh Aufreinigung von Substanzen aus einer biologischen Probe
KR100217311B1 (ko) 1997-10-20 1999-09-01 이서봉 소수성 지지막 위에 박막의 친수성 도포층을 갖는 복합막의제조방법
US6780852B2 (en) * 1997-12-09 2004-08-24 Bo E. Hedlund Modified polysaccharides exhibiting altered biological recognition
US6613234B2 (en) * 1998-04-06 2003-09-02 Ciphergen Biosystems, Inc. Large pore volume composite mineral oxide beads, their preparation and their applications for adsorption and chromatography
US6780582B1 (en) 1998-07-14 2004-08-24 Zyomyx, Inc. Arrays of protein-capture agents and methods of use thereof
SE9802882D0 (sv) 1998-08-28 1998-08-28 Amersham Pharm Biotech Ab Kompositmaterial och dess användning
US6875085B2 (en) * 1998-11-06 2005-04-05 Mosel Vitelic, Inc. Polishing system including a hydrostatic fluid bearing support
US6277489B1 (en) 1998-12-04 2001-08-21 The Regents Of The University Of California Support for high performance affinity chromatography and other uses
DE60043597D1 (de) 1999-02-25 2010-02-04 Pall Corp Positiv geladene Membran
CA2364839C (en) 1999-02-25 2008-08-19 Pall Corporation Negatively charged membrane
US8158002B1 (en) * 1999-03-17 2012-04-17 Foster-Miller, Inc. Responsive gels and methods of use thereof
AU5003600A (en) 1999-05-14 2000-12-05 Pall Corporation Charged membrane
WO2001008792A2 (en) 1999-07-30 2001-02-08 Genentech, Inc. Charged filtration membranes and uses therefor
DE19943921C1 (de) 1999-09-14 2001-01-11 Sartorius Gmbh Partikelgängige Vorrichtung zur Durchführung von Stofftrennungen mittels poröser flächiger Adsorptionsmembranen
CA2422738C (en) 2000-10-05 2007-06-26 Rensselaer Polytechnic Institute Uv-assisted grafting of pes and psf membranes
US6528325B1 (en) 2000-10-13 2003-03-04 Dexall Biomedical Labs, Inc. Method for the visual detection of specific antibodies in human serum by the use of lateral flow assays
WO2002046398A2 (en) 2000-11-06 2002-06-13 The University Of Houston System Nucleic acid separation using immobilized metal affinity chromatography
CA2428280A1 (en) 2000-11-13 2002-05-16 Mcmaster University Gas separation device
US6989452B2 (en) 2001-05-31 2006-01-24 Medarex, Inc. Disulfide prodrugs and linkers and stabilizers useful therefor
EP1397686B1 (en) 2001-06-07 2006-10-18 Electrophoretics Limited Method for characterizing polypeptides
ITRM20010336A1 (it) * 2001-06-13 2002-12-13 Biostrands S R L Anticorpo umano ricombinante diretto contro la proteina non strutturale ns3 del virus dell'epatite c (hcv), acido nucleico codificante e usi
CA2454323C (en) * 2001-07-20 2011-05-31 Mcmaster University Asymmetric gel-filled microporous membranes
US6766817B2 (en) 2001-07-25 2004-07-27 Tubarc Technologies, Llc Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action
KR100952265B1 (ko) 2001-11-26 2010-04-09 인비스타 테크놀러지스 에스.에이.알.엘. 지지된 비스(인) 리간드 및 촉매 작용에 있어서의 그의용도
AU2003234159A1 (en) 2002-04-22 2003-11-03 Purdue Research Foundation Hydrogels having enhanced elasticity and mechanical strength properties
WO2004047724A2 (en) 2002-05-16 2004-06-10 Genelabs Technologies, Inc Aryl and heteroaryl compounds as antibacterial and antifungal agents
US7285255B2 (en) 2002-12-10 2007-10-23 Ecolab Inc. Deodorizing and sanitizing employing a wicking device
DE602004024190D1 (de) 2003-02-19 2009-12-31 Natrix Separations Inc Geträgerte poröse gele umfassende verbundmaterialien
US7479222B2 (en) 2004-02-05 2009-01-20 Millipore Corporation Porous adsorptive or chromatographic media
CN100548455C (zh) * 2004-09-30 2009-10-14 麦克马斯特大学 包括层状亲水性涂层的复合材料

Also Published As

Publication number Publication date
AU2009230738A1 (en) 2009-11-12
US8187880B2 (en) 2012-05-29
KR101113201B1 (ko) 2012-04-12
EP2143482A1 (en) 2010-01-13
US8652849B2 (en) 2014-02-18
JP2006519273A (ja) 2006-08-24
WO2004073843A1 (en) 2004-09-02
DE602004024190D1 (de) 2009-12-31
US20090032463A1 (en) 2009-02-05
CA2514471A1 (en) 2004-09-02
JP2011149024A (ja) 2011-08-04
US20100047551A1 (en) 2010-02-25
AU2004212641B2 (en) 2009-08-06
US8206958B2 (en) 2012-06-26
AU2009230738B2 (en) 2011-08-04
JP5189286B2 (ja) 2013-04-24
ATE448866T1 (de) 2009-12-15
EP1617936A1 (en) 2006-01-25
US20080314831A1 (en) 2008-12-25
US8367809B2 (en) 2013-02-05
JP5432934B2 (ja) 2014-03-05
US20080312416A1 (en) 2008-12-18
US20040203149A1 (en) 2004-10-14
US20090008328A1 (en) 2009-01-08
US8192971B2 (en) 2012-06-05
KR20050107440A (ko) 2005-11-11
US20090029438A1 (en) 2009-01-29
US20090035552A1 (en) 2009-02-05
AU2004212641A1 (en) 2004-09-02
US8383782B2 (en) 2013-02-26
EP2143481A1 (en) 2010-01-13
US8211682B2 (en) 2012-07-03
US20100044316A1 (en) 2010-02-25
EP1617936B1 (en) 2009-11-18
US8206982B2 (en) 2012-06-26
US7316919B2 (en) 2008-01-08

Similar Documents

Publication Publication Date Title
CA2514471C (en) Composite materials comprising supported porous gels
CA2564413C (en) Stable composite material comprising supported porous gels
CA2558859C (en) Membrane stacks
AU2011203555B2 (en) Composite materials comprising supported porous gels

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20240129