BRPI0608100A2 - materiais poliméricos altamente porosos compreendendo moléculas biologicamente ativas através de enxerto covalente - Google Patents
materiais poliméricos altamente porosos compreendendo moléculas biologicamente ativas através de enxerto covalenteInfo
- Publication number
- BRPI0608100A2 BRPI0608100A2 BRPI0608100-2A BRPI0608100A BRPI0608100A2 BR PI0608100 A2 BRPI0608100 A2 BR PI0608100A2 BR PI0608100 A BRPI0608100 A BR PI0608100A BR PI0608100 A2 BRPI0608100 A2 BR PI0608100A2
- Authority
- BR
- Brazil
- Prior art keywords
- biologically active
- highly porous
- species
- porous polymeric
- polymeric materials
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/32—Polymerisation in water-in-oil emulsions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
- C12N11/087—Acrylic polymers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Pharmacology & Pharmacy (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Graft Or Block Polymers (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
- Materials For Medical Uses (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Abstract
MATERIAIS POLIMêRICOS ALTAMENTE POROSOS COMPREENDENDO MOLéCULAS BIOLOGICAMENTE ATIVAS ATRAVéS DE ENXERTO COVALENTE. A presente invenção se refere aos materiais poliméricos altamente porosos, compreendendo espécies biologicamente ativas, enxertadas covalentemente. A invenção também se refere a um processo para a preparação de materiais altamente porosos, compreendendo monómeros funcionais capazes de enxerto em espécies moleculares biologicamente ativas compreendendo as etapas de: (a) preparação de uma composição em emulsão compreendendo uma fase em gotícula e uma fase contínua e contendo monómeros, (b) cura da emulsão e (c) remoção opcional da fase aquosa/em gotículas. A invenção se refere adicionalmente a um processo para enxerto de espécies biologicamente ativas em tal material polimérico altamente poroso compreendendo as etapas de: (i) exposição do material altamente poroso a uma solução de espécies moleculares biologicamente ativas em um meio solvente apropriado, (ii) adição opcional de um agente de ativação, (iii) aquecimento opcional e (iv) enxágúe do material poroso com um meio solvente para remover espécies não enxertadas. Os materiais poliméricos altamente porosos compreendendo espécies biologicamente ativas covalentemente enxertadas podem ser usados, por exemplo, como um catalisador heterogêneo, em biosensores, para cromatograf ia, em dispositivos biomédicos e em implantes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05075957 | 2005-04-22 | ||
PCT/EP2006/003677 WO2006111399A2 (en) | 2005-04-22 | 2006-04-21 | Highly porous polymeric materials comprising biologically active molecules via covalent grafting |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0608100A2 true BRPI0608100A2 (pt) | 2009-11-03 |
Family
ID=36974715
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0608100-2A BRPI0608100A2 (pt) | 2005-04-22 | 2006-04-21 | materiais poliméricos altamente porosos compreendendo moléculas biologicamente ativas através de enxerto covalente |
Country Status (7)
Country | Link |
---|---|
US (1) | US20090215913A1 (pt) |
EP (1) | EP1871878A2 (pt) |
JP (1) | JP2008536986A (pt) |
KR (1) | KR20080010402A (pt) |
CN (1) | CN101163789A (pt) |
BR (1) | BRPI0608100A2 (pt) |
WO (1) | WO2006111399A2 (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2734294A1 (fr) * | 2008-08-13 | 2010-02-18 | Long Lasting Innovation - L2I (Societe A Responsabilite Limitee) | Procede pour la fixation de molecules actives sur un support, element actif obtenu par ce procede et composition chimique pour la mise en oeuvre de ce procede |
US20130203602A1 (en) | 2010-03-11 | 2013-08-08 | Danmarks Tekniske Universitet | Supported biologically active compounds |
US8889760B2 (en) * | 2010-03-30 | 2014-11-18 | Surmodics, Inc. | Photoactivatable crosslinker |
US9062245B2 (en) | 2011-02-09 | 2015-06-23 | Technion Research & Development Foundation Limited | Liquid-retaining elastomeric compositions |
US9180094B2 (en) | 2011-10-12 | 2015-11-10 | The Texas A&M University System | High porosity materials, scaffolds, and method of making |
US20160243277A1 (en) * | 2013-09-23 | 2016-08-25 | The Texas A & M University System | Fast curing porous materials and control thereof |
US10363215B2 (en) | 2013-11-08 | 2019-07-30 | The Texas A&M University System | Porous microparticles with high loading efficiencies |
IL245656B (en) | 2016-05-16 | 2018-02-28 | Technion Res & Dev Foundation | Polymer structures with high absorption capacity |
WO2018002916A1 (en) | 2016-06-26 | 2018-01-04 | Technion Research & Development Foundation Limited | Hhh |
IL247302B (en) | 2016-08-16 | 2019-03-31 | Technion Res & Dev Foundation | Systems for releasing materials based on polymer emulsions |
CN107164359B (zh) * | 2017-06-30 | 2020-03-17 | 鲁东大学 | 一种具有良好热稳定性的葡萄糖氧化酶纳米凝胶的制备方法 |
IL253431A0 (en) | 2017-07-11 | 2017-09-28 | Technion Res & Dev Foundation | Flexible compounds store liquids, their preparation processes and their uses |
WO2019016816A1 (en) | 2017-07-19 | 2019-01-24 | Technion Research & Development Foundation Limited | HYDROGELS WITH EMULSION MATRIX DOUBLELY RETICULATED BY REVERSIBLE METAL COORDINATION |
IL255404B (en) | 2017-11-02 | 2018-10-31 | Technion Res & Dev Foundation | A zwitterionic hydrogel in the configuration of an internal multiphase emulsion |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3130924A1 (de) * | 1981-08-05 | 1983-02-17 | Röhm GmbH, 6100 Darmstadt | Oberflaechenreiche systeme zur fixierung von nucleophile gruppen enthaltenden substraten |
DE3629177A1 (de) * | 1986-08-28 | 1988-03-17 | Hoechst Ag | Vernetzte polymerisate und verfahren zu ihrer herstellung |
GB8729889D0 (en) * | 1987-12-22 | 1988-02-03 | Unilever Plc | Bio-catalysts support systems |
JPH08322915A (ja) * | 1995-05-29 | 1996-12-10 | Synbolon Corp | 病原体の失活方法 |
JPH11322997A (ja) * | 1998-05-14 | 1999-11-26 | Dainippon Ink & Chem Inc | 多孔質ビーズの製造方法 |
EP1617936B1 (en) * | 2003-02-19 | 2009-11-18 | Natrix Separations Inc. | Composite materials comprising supported porous gels |
-
2006
- 2006-04-21 US US11/918,777 patent/US20090215913A1/en not_active Abandoned
- 2006-04-21 JP JP2008507009A patent/JP2008536986A/ja active Pending
- 2006-04-21 KR KR1020077025292A patent/KR20080010402A/ko not_active Application Discontinuation
- 2006-04-21 BR BRPI0608100-2A patent/BRPI0608100A2/pt not_active IP Right Cessation
- 2006-04-21 EP EP06753399A patent/EP1871878A2/en not_active Withdrawn
- 2006-04-21 WO PCT/EP2006/003677 patent/WO2006111399A2/en active Application Filing
- 2006-04-21 CN CNA2006800135977A patent/CN101163789A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2006111399A2 (en) | 2006-10-26 |
CN101163789A (zh) | 2008-04-16 |
WO2006111399A8 (en) | 2006-12-28 |
US20090215913A1 (en) | 2009-08-27 |
KR20080010402A (ko) | 2008-01-30 |
JP2008536986A (ja) | 2008-09-11 |
WO2006111399A3 (en) | 2007-02-08 |
EP1871878A2 (en) | 2008-01-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A E 6A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2161 DE 05/06/2012. |
|
B15K | Others concerning applications: alteration of classification |
Ipc: C12N 11/06 (2006.01), C12N 11/08 (2006.01) |