CA2498636C - Use of saccharomyces cerevisiae erg4 mutants for the expression of glucose transporters from mammals - Google Patents

Use of saccharomyces cerevisiae erg4 mutants for the expression of glucose transporters from mammals Download PDF

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Publication number
CA2498636C
CA2498636C CA2498636A CA2498636A CA2498636C CA 2498636 C CA2498636 C CA 2498636C CA 2498636 A CA2498636 A CA 2498636A CA 2498636 A CA2498636 A CA 2498636A CA 2498636 C CA2498636 C CA 2498636C
Authority
CA
Canada
Prior art keywords
protein
yeast cell
yeast
polynucleotide
glucose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2498636A
Other languages
English (en)
French (fr)
Other versions
CA2498636A1 (en
Inventor
Guenter Mueller
Silke Dlugai
Dorthe Voss
Eckhard Boles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Sanofi Aventis Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH
Publication of CA2498636A1 publication Critical patent/CA2498636A1/en
Application granted granted Critical
Publication of CA2498636C publication Critical patent/CA2498636C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2498636A 2002-09-14 2003-09-04 Use of saccharomyces cerevisiae erg4 mutants for the expression of glucose transporters from mammals Expired - Fee Related CA2498636C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10242763.1 2002-09-14
DE10242763A DE10242763A1 (de) 2002-09-14 2002-09-14 Verwendung von Saccharomyces cerevisiae erg4-Mutanten zur Expression von Glukosetransportern aus Säugetieren
PCT/EP2003/009812 WO2004026907A2 (de) 2002-09-14 2003-09-04 Verwendung von saccharomyces cerevisiae erg4-mutanten zur expression von glukosetransportern aus säugetieren

Publications (2)

Publication Number Publication Date
CA2498636A1 CA2498636A1 (en) 2004-04-01
CA2498636C true CA2498636C (en) 2012-04-17

Family

ID=31724774

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2498636A Expired - Fee Related CA2498636C (en) 2002-09-14 2003-09-04 Use of saccharomyces cerevisiae erg4 mutants for the expression of glucose transporters from mammals

Country Status (15)

Country Link
EP (1) EP1539958A2 (de)
JP (1) JP4520854B2 (de)
KR (1) KR101233998B1 (de)
CN (1) CN1694960B (de)
AU (1) AU2003264257B2 (de)
BR (1) BR0314115A (de)
CA (1) CA2498636C (de)
DE (1) DE10242763A1 (de)
HK (1) HK1084401A1 (de)
IL (2) IL167321A (de)
MX (1) MXPA05002816A (de)
NO (1) NO20051795L (de)
RU (1) RU2345136C2 (de)
WO (1) WO2004026907A2 (de)
ZA (1) ZA200501871B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102899328A (zh) * 2012-09-28 2013-01-30 南京农业大学 山羊葡萄糖转运载体4基因及其重组表达载体和应用
CN110408616B (zh) * 2019-07-09 2021-06-15 中南民族大学 GLUT4基因敲除的sgRNA、A549细胞系及其构建方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942398A (en) * 1998-02-26 1999-08-24 Millennium Pharmaceuticals, Inc. Nucleic acid molecules encoding glutx and uses thereof
AU5477500A (en) * 1999-06-09 2000-12-28 General Hospital Corporation, The Method of measuring plasma membrane targeting of glut4
DE10106718A1 (de) * 2001-02-14 2002-09-05 Aventis Pharma Gmbh Hefestamm von Saccharomyces cerevisiae mit funktioneller Expression eines Glut-Transporters

Also Published As

Publication number Publication date
EP1539958A2 (de) 2005-06-15
WO2004026907A2 (de) 2004-04-01
ZA200501871B (en) 2005-10-26
CN1694960A (zh) 2005-11-09
AU2003264257B2 (en) 2010-05-20
KR20050056206A (ko) 2005-06-14
BR0314115A (pt) 2005-07-12
RU2005110955A (ru) 2006-01-20
KR101233998B1 (ko) 2013-02-18
CA2498636A1 (en) 2004-04-01
CN1694960B (zh) 2010-05-12
WO2004026907A3 (de) 2004-11-11
MXPA05002816A (es) 2005-05-27
IL197621A0 (en) 2011-08-01
JP4520854B2 (ja) 2010-08-11
DE10242763A1 (de) 2004-03-18
RU2345136C2 (ru) 2009-01-27
JP2006517088A (ja) 2006-07-20
IL197621A (en) 2014-01-30
IL167321A (en) 2013-11-28
HK1084401A1 (en) 2006-07-28
NO20051795L (no) 2005-06-08
AU2003264257A1 (en) 2004-04-08

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