JP4520854B2 - 哺乳動物由来のグルコーストランスポーターの発現のための、サッカロミセス・セレビジエErg4突然変異体の使用 - Google Patents

哺乳動物由来のグルコーストランスポーターの発現のための、サッカロミセス・セレビジエErg4突然変異体の使用 Download PDF

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JP4520854B2
JP4520854B2 JP2004536979A JP2004536979A JP4520854B2 JP 4520854 B2 JP4520854 B2 JP 4520854B2 JP 2004536979 A JP2004536979 A JP 2004536979A JP 2004536979 A JP2004536979 A JP 2004536979A JP 4520854 B2 JP4520854 B2 JP 4520854B2
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protein
yeast
glucose
yeast cell
polynucleotide
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Japanese (ja)
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JP2006517088A (ja
Inventor
ギュンター・ミュラー
ジルケ・ドルーガイ
デルテ・フォス
エックハルト・ボーレス
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サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • C12N1/18Baker's yeast; Brewer's yeast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2004536979A 2002-09-14 2003-09-04 哺乳動物由来のグルコーストランスポーターの発現のための、サッカロミセス・セレビジエErg4突然変異体の使用 Expired - Fee Related JP4520854B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10242763A DE10242763A1 (de) 2002-09-14 2002-09-14 Verwendung von Saccharomyces cerevisiae erg4-Mutanten zur Expression von Glukosetransportern aus Säugetieren
PCT/EP2003/009812 WO2004026907A2 (de) 2002-09-14 2003-09-04 Verwendung von saccharomyces cerevisiae erg4-mutanten zur expression von glukosetransportern aus säugetieren

Publications (2)

Publication Number Publication Date
JP2006517088A JP2006517088A (ja) 2006-07-20
JP4520854B2 true JP4520854B2 (ja) 2010-08-11

Family

ID=31724774

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JP2004536979A Expired - Fee Related JP4520854B2 (ja) 2002-09-14 2003-09-04 哺乳動物由来のグルコーストランスポーターの発現のための、サッカロミセス・セレビジエErg4突然変異体の使用

Country Status (15)

Country Link
EP (1) EP1539958A2 (de)
JP (1) JP4520854B2 (de)
KR (1) KR101233998B1 (de)
CN (1) CN1694960B (de)
AU (1) AU2003264257B2 (de)
BR (1) BR0314115A (de)
CA (1) CA2498636C (de)
DE (1) DE10242763A1 (de)
HK (1) HK1084401A1 (de)
IL (2) IL167321A (de)
MX (1) MXPA05002816A (de)
NO (1) NO20051795L (de)
RU (1) RU2345136C2 (de)
WO (1) WO2004026907A2 (de)
ZA (1) ZA200501871B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102899328A (zh) * 2012-09-28 2013-01-30 南京农业大学 山羊葡萄糖转运载体4基因及其重组表达载体和应用
CN110408616B (zh) * 2019-07-09 2021-06-15 中南民族大学 GLUT4基因敲除的sgRNA、A549细胞系及其构建方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6303373B1 (en) * 1999-06-09 2001-10-16 Whitehead Institute For Biomedical Research Method of measuring plasma membrane targeting of GLUT4
US5942398A (en) * 1998-02-26 1999-08-24 Millennium Pharmaceuticals, Inc. Nucleic acid molecules encoding glutx and uses thereof
DE10106718A1 (de) * 2001-02-14 2002-09-05 Aventis Pharma Gmbh Hefestamm von Saccharomyces cerevisiae mit funktioneller Expression eines Glut-Transporters

Also Published As

Publication number Publication date
WO2004026907A2 (de) 2004-04-01
AU2003264257A1 (en) 2004-04-08
RU2345136C2 (ru) 2009-01-27
CA2498636A1 (en) 2004-04-01
CA2498636C (en) 2012-04-17
RU2005110955A (ru) 2006-01-20
NO20051795L (no) 2005-06-08
EP1539958A2 (de) 2005-06-15
ZA200501871B (en) 2005-10-26
KR101233998B1 (ko) 2013-02-18
WO2004026907A3 (de) 2004-11-11
CN1694960A (zh) 2005-11-09
HK1084401A1 (en) 2006-07-28
AU2003264257B2 (en) 2010-05-20
KR20050056206A (ko) 2005-06-14
IL197621A0 (en) 2011-08-01
BR0314115A (pt) 2005-07-12
MXPA05002816A (es) 2005-05-27
IL167321A (en) 2013-11-28
DE10242763A1 (de) 2004-03-18
JP2006517088A (ja) 2006-07-20
IL197621A (en) 2014-01-30
CN1694960B (zh) 2010-05-12

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