IL197621A - Saccharomyces cerevisiae erg4 mutants and methods of identifying compounds inhibiting the activity of the corresponding protein of the fgy1 gene - Google Patents

Saccharomyces cerevisiae erg4 mutants and methods of identifying compounds inhibiting the activity of the corresponding protein of the fgy1 gene

Info

Publication number
IL197621A
IL197621A IL197621A IL19762109A IL197621A IL 197621 A IL197621 A IL 197621A IL 197621 A IL197621 A IL 197621A IL 19762109 A IL19762109 A IL 19762109A IL 197621 A IL197621 A IL 197621A
Authority
IL
Israel
Prior art keywords
erg4
mutants
activity
methods
saccharomyces cerevisiae
Prior art date
Application number
IL197621A
Other languages
Hebrew (he)
Other versions
IL197621A0 (en
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of IL197621A0 publication Critical patent/IL197621A0/en
Publication of IL197621A publication Critical patent/IL197621A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL197621A 2002-09-14 2009-03-16 Saccharomyces cerevisiae erg4 mutants and methods of identifying compounds inhibiting the activity of the corresponding protein of the fgy1 gene IL197621A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10242763A DE10242763A1 (en) 2002-09-14 2002-09-14 New polynucleotide encoding mutant human glucose transporter, useful for identifying antidiabetic agents that can be used to treat diabetes types I or II
PCT/EP2003/009812 WO2004026907A2 (en) 2002-09-14 2003-09-04 Use of saccharomyces cerevisiae erg4 mutants for the expression of glucose transporters from mammals

Publications (2)

Publication Number Publication Date
IL197621A0 IL197621A0 (en) 2011-08-01
IL197621A true IL197621A (en) 2014-01-30

Family

ID=31724774

Family Applications (2)

Application Number Title Priority Date Filing Date
IL167321A IL167321A (en) 2002-09-14 2005-03-08 Polynucleotide comprising a dna sequence encoding a glucose transporter 4, a yeast cell comprising such a polynucleotide and a process for preparing such a yeast cell
IL197621A IL197621A (en) 2002-09-14 2009-03-16 Saccharomyces cerevisiae erg4 mutants and methods of identifying compounds inhibiting the activity of the corresponding protein of the fgy1 gene

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL167321A IL167321A (en) 2002-09-14 2005-03-08 Polynucleotide comprising a dna sequence encoding a glucose transporter 4, a yeast cell comprising such a polynucleotide and a process for preparing such a yeast cell

Country Status (15)

Country Link
EP (1) EP1539958A2 (en)
JP (1) JP4520854B2 (en)
KR (1) KR101233998B1 (en)
CN (1) CN1694960B (en)
AU (1) AU2003264257B2 (en)
BR (1) BR0314115A (en)
CA (1) CA2498636C (en)
DE (1) DE10242763A1 (en)
HK (1) HK1084401A1 (en)
IL (2) IL167321A (en)
MX (1) MXPA05002816A (en)
NO (1) NO20051795L (en)
RU (1) RU2345136C2 (en)
WO (1) WO2004026907A2 (en)
ZA (1) ZA200501871B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102899328A (en) * 2012-09-28 2013-01-30 南京农业大学 Goat glucose transporter 4 gene as well as recombinant expression vector and application of gene
CN110408616B (en) * 2019-07-09 2021-06-15 中南民族大学 GLUT4 gene knockout sgRNA and A549 cell lines and construction method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6303373B1 (en) * 1999-06-09 2001-10-16 Whitehead Institute For Biomedical Research Method of measuring plasma membrane targeting of GLUT4
US5942398A (en) * 1998-02-26 1999-08-24 Millennium Pharmaceuticals, Inc. Nucleic acid molecules encoding glutx and uses thereof
DE10106718A1 (en) * 2001-02-14 2002-09-05 Aventis Pharma Gmbh Yeast strain of Saccharomyces cerevisiae with functional expression of a glow transporter

Also Published As

Publication number Publication date
WO2004026907A2 (en) 2004-04-01
AU2003264257A1 (en) 2004-04-08
RU2345136C2 (en) 2009-01-27
CA2498636A1 (en) 2004-04-01
CA2498636C (en) 2012-04-17
RU2005110955A (en) 2006-01-20
NO20051795L (en) 2005-06-08
EP1539958A2 (en) 2005-06-15
ZA200501871B (en) 2005-10-26
KR101233998B1 (en) 2013-02-18
WO2004026907A3 (en) 2004-11-11
CN1694960A (en) 2005-11-09
HK1084401A1 (en) 2006-07-28
JP4520854B2 (en) 2010-08-11
AU2003264257B2 (en) 2010-05-20
KR20050056206A (en) 2005-06-14
IL197621A0 (en) 2011-08-01
BR0314115A (en) 2005-07-12
MXPA05002816A (en) 2005-05-27
IL167321A (en) 2013-11-28
DE10242763A1 (en) 2004-03-18
JP2006517088A (en) 2006-07-20
CN1694960B (en) 2010-05-12

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees