NO20051795L - Use of Saccharomyces cerevisiae ERG4 Mutants for Expression of Glucose Transporters from Mammals - Google Patents

Use of Saccharomyces cerevisiae ERG4 Mutants for Expression of Glucose Transporters from Mammals

Info

Publication number
NO20051795L
NO20051795L NO20051795A NO20051795A NO20051795L NO 20051795 L NO20051795 L NO 20051795L NO 20051795 A NO20051795 A NO 20051795A NO 20051795 A NO20051795 A NO 20051795A NO 20051795 L NO20051795 L NO 20051795L
Authority
NO
Norway
Prior art keywords
erg4
mutants
mammals
expression
saccharomyces cerevisiae
Prior art date
Application number
NO20051795A
Other languages
Norwegian (no)
Inventor
Guenter Mueller
Silke Dlugai
Dorthe Voss
Eckhard Boles
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of NO20051795L publication Critical patent/NO20051795L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • C12N1/18Baker's yeast; Brewer's yeast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Oppfinneslen angår gjærstammer der en human GLUT4-transportør eller en human GLUTI-transportør funksjonelt kan uttrykkes og angår spesielt GLUT4transportproteiner som funksjonelt kan uttrykkes enkelt i gjærstammer.The invention relates to yeast strains in which a human GLUT4 transporter or a human GLUTI transporter can be functionally expressed and particularly relates to GLUT4 transporter proteins which can be functionally expressed simply in yeast strains.

NO20051795A 2002-09-14 2005-04-12 Use of Saccharomyces cerevisiae ERG4 Mutants for Expression of Glucose Transporters from Mammals NO20051795L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10242763A DE10242763A1 (en) 2002-09-14 2002-09-14 New polynucleotide encoding mutant human glucose transporter, useful for identifying antidiabetic agents that can be used to treat diabetes types I or II
PCT/EP2003/009812 WO2004026907A2 (en) 2002-09-14 2003-09-04 Use of saccharomyces cerevisiae erg4 mutants for the expression of glucose transporters from mammals

Publications (1)

Publication Number Publication Date
NO20051795L true NO20051795L (en) 2005-06-08

Family

ID=31724774

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20051795A NO20051795L (en) 2002-09-14 2005-04-12 Use of Saccharomyces cerevisiae ERG4 Mutants for Expression of Glucose Transporters from Mammals

Country Status (15)

Country Link
EP (1) EP1539958A2 (en)
JP (1) JP4520854B2 (en)
KR (1) KR101233998B1 (en)
CN (1) CN1694960B (en)
AU (1) AU2003264257B2 (en)
BR (1) BR0314115A (en)
CA (1) CA2498636C (en)
DE (1) DE10242763A1 (en)
HK (1) HK1084401A1 (en)
IL (2) IL167321A (en)
MX (1) MXPA05002816A (en)
NO (1) NO20051795L (en)
RU (1) RU2345136C2 (en)
WO (1) WO2004026907A2 (en)
ZA (1) ZA200501871B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102899328A (en) * 2012-09-28 2013-01-30 南京农业大学 Goat glucose transporter 4 gene as well as recombinant expression vector and application of gene
CN110408616B (en) * 2019-07-09 2021-06-15 中南民族大学 GLUT4 gene knockout sgRNA and A549 cell lines and construction method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942398A (en) * 1998-02-26 1999-08-24 Millennium Pharmaceuticals, Inc. Nucleic acid molecules encoding glutx and uses thereof
EP1189943A1 (en) * 1999-06-09 2002-03-27 Whitehead Institute For Biomedical Research Method of measuring plasma membrane targeting of glut4
DE10106718A1 (en) * 2001-02-14 2002-09-05 Aventis Pharma Gmbh Yeast strain of Saccharomyces cerevisiae with functional expression of a glow transporter

Also Published As

Publication number Publication date
IL197621A (en) 2014-01-30
KR20050056206A (en) 2005-06-14
ZA200501871B (en) 2005-10-26
BR0314115A (en) 2005-07-12
RU2345136C2 (en) 2009-01-27
IL197621A0 (en) 2011-08-01
KR101233998B1 (en) 2013-02-18
RU2005110955A (en) 2006-01-20
HK1084401A1 (en) 2006-07-28
WO2004026907A2 (en) 2004-04-01
JP2006517088A (en) 2006-07-20
AU2003264257B2 (en) 2010-05-20
MXPA05002816A (en) 2005-05-27
CA2498636A1 (en) 2004-04-01
DE10242763A1 (en) 2004-03-18
CN1694960A (en) 2005-11-09
JP4520854B2 (en) 2010-08-11
CA2498636C (en) 2012-04-17
WO2004026907A3 (en) 2004-11-11
IL167321A (en) 2013-11-28
CN1694960B (en) 2010-05-12
AU2003264257A1 (en) 2004-04-08
EP1539958A2 (en) 2005-06-15

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