BR0314115A - Use of saccharomyces cerevisiae erg4 mutants for expression of mammalian glucose transporters - Google Patents

Use of saccharomyces cerevisiae erg4 mutants for expression of mammalian glucose transporters

Info

Publication number
BR0314115A
BR0314115A BR0314115-2A BR0314115A BR0314115A BR 0314115 A BR0314115 A BR 0314115A BR 0314115 A BR0314115 A BR 0314115A BR 0314115 A BR0314115 A BR 0314115A
Authority
BR
Brazil
Prior art keywords
erg4
mutants
expression
saccharomyces cerevisiae
glucose transporters
Prior art date
Application number
BR0314115-2A
Other languages
Portuguese (pt)
Inventor
Guenter Mueller
Silke Dlugai
Doerthe Voss
Eckhard Boles
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of BR0314115A publication Critical patent/BR0314115A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Botany (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"UTILIZAçãO DE MUTANTES ERG4 DE SACCHAROMYCES CEREVISIAE PARA EXPRESSãO DE TRANSPORTADORES DE GLICOSE DE MAMìFEROS". A invenção refere-se a cepas de levedura nas quais um transportador humano GLUT4 ou um transportador humano GLUT1 pode ser funcionalmente expresso, bem como de determinadas proteínas transportadoras GLUT4, as quais podem ser funcionalmente expressas em cepas de levedura de maneira especialmente fácil."USE OF SACCHAROMYCES CEREVISIAE ERG4 MUTANTS FOR EXPRESSION OF MAMMALIAN GLUCOSE CARRIERS". The invention relates to yeast strains in which a human GLUT4 transporter or a human GLUT1 transporter may be functionally expressed, as well as certain GLUT4 carrier proteins, which may be functionally expressed in yeast strains especially easily.

BR0314115-2A 2002-09-14 2003-09-04 Use of saccharomyces cerevisiae erg4 mutants for expression of mammalian glucose transporters BR0314115A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10242763A DE10242763A1 (en) 2002-09-14 2002-09-14 New polynucleotide encoding mutant human glucose transporter, useful for identifying antidiabetic agents that can be used to treat diabetes types I or II
PCT/EP2003/009812 WO2004026907A2 (en) 2002-09-14 2003-09-04 Use of saccharomyces cerevisiae erg4 mutants for the expression of glucose transporters from mammals

Publications (1)

Publication Number Publication Date
BR0314115A true BR0314115A (en) 2005-07-12

Family

ID=31724774

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0314115-2A BR0314115A (en) 2002-09-14 2003-09-04 Use of saccharomyces cerevisiae erg4 mutants for expression of mammalian glucose transporters

Country Status (15)

Country Link
EP (1) EP1539958A2 (en)
JP (1) JP4520854B2 (en)
KR (1) KR101233998B1 (en)
CN (1) CN1694960B (en)
AU (1) AU2003264257B2 (en)
BR (1) BR0314115A (en)
CA (1) CA2498636C (en)
DE (1) DE10242763A1 (en)
HK (1) HK1084401A1 (en)
IL (2) IL167321A (en)
MX (1) MXPA05002816A (en)
NO (1) NO20051795L (en)
RU (1) RU2345136C2 (en)
WO (1) WO2004026907A2 (en)
ZA (1) ZA200501871B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102899328A (en) * 2012-09-28 2013-01-30 南京农业大学 Goat glucose transporter 4 gene as well as recombinant expression vector and application of gene
CN110408616B (en) * 2019-07-09 2021-06-15 中南民族大学 GLUT4 gene knockout sgRNA and A549 cell lines and construction method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6303373B1 (en) * 1999-06-09 2001-10-16 Whitehead Institute For Biomedical Research Method of measuring plasma membrane targeting of GLUT4
US5942398A (en) * 1998-02-26 1999-08-24 Millennium Pharmaceuticals, Inc. Nucleic acid molecules encoding glutx and uses thereof
DE10106718A1 (en) * 2001-02-14 2002-09-05 Aventis Pharma Gmbh Yeast strain of Saccharomyces cerevisiae with functional expression of a glow transporter

Also Published As

Publication number Publication date
AU2003264257B2 (en) 2010-05-20
IL167321A (en) 2013-11-28
KR101233998B1 (en) 2013-02-18
ZA200501871B (en) 2005-10-26
EP1539958A2 (en) 2005-06-15
WO2004026907A3 (en) 2004-11-11
MXPA05002816A (en) 2005-05-27
CN1694960B (en) 2010-05-12
JP2006517088A (en) 2006-07-20
IL197621A (en) 2014-01-30
RU2345136C2 (en) 2009-01-27
CA2498636C (en) 2012-04-17
WO2004026907A2 (en) 2004-04-01
HK1084401A1 (en) 2006-07-28
AU2003264257A1 (en) 2004-04-08
CN1694960A (en) 2005-11-09
DE10242763A1 (en) 2004-03-18
JP4520854B2 (en) 2010-08-11
NO20051795L (en) 2005-06-08
KR20050056206A (en) 2005-06-14
RU2005110955A (en) 2006-01-20
IL197621A0 (en) 2011-08-01
CA2498636A1 (en) 2004-04-01

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2322 DE 07-07-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.