CA2306155A1 - Use of quinazoline derivatives as tyrosine kinase inhibitors for treating colonic polyps - Google Patents

Use of quinazoline derivatives as tyrosine kinase inhibitors for treating colonic polyps Download PDF

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Publication number
CA2306155A1
CA2306155A1 CA002306155A CA2306155A CA2306155A1 CA 2306155 A1 CA2306155 A1 CA 2306155A1 CA 002306155 A CA002306155 A CA 002306155A CA 2306155 A CA2306155 A CA 2306155A CA 2306155 A1 CA2306155 A1 CA 2306155A1
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CA
Canada
Prior art keywords
amino
carbon atoms
bromophenyl
quinazolinyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002306155A
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English (en)
French (fr)
Inventor
Philip Frost
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Wyeth Holdings LLC
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Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2306155A1 publication Critical patent/CA2306155A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002306155A 1997-11-06 1998-11-04 Use of quinazoline derivatives as tyrosine kinase inhibitors for treating colonic polyps Abandoned CA2306155A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96508497A 1997-11-06 1997-11-06
US08/965,084 1997-11-06
PCT/US1998/023549 WO1999024037A1 (en) 1997-11-06 1998-11-04 Use of quinazoline derivatives as tyrosine kinase inhibitors for treating colonic polyps

Publications (1)

Publication Number Publication Date
CA2306155A1 true CA2306155A1 (en) 1999-05-20

Family

ID=25509419

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002306155A Abandoned CA2306155A1 (en) 1997-11-06 1998-11-04 Use of quinazoline derivatives as tyrosine kinase inhibitors for treating colonic polyps

Country Status (15)

Country Link
EP (1) EP1039910A1 (no)
JP (1) JP2001522802A (no)
KR (1) KR20010031813A (no)
CN (1) CN1278176A (no)
AR (1) AR016415A1 (no)
AU (1) AU1308799A (no)
BR (1) BR9814116A (no)
CA (1) CA2306155A1 (no)
HU (1) HUP0004286A3 (no)
IL (1) IL135622A0 (no)
NO (1) NO20002166L (no)
NZ (1) NZ503991A (no)
PL (1) PL340800A1 (no)
WO (1) WO1999024037A1 (no)
ZA (1) ZA9810134B (no)

Families Citing this family (147)

* Cited by examiner, † Cited by third party
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