CA1201443A - PROCEDE DE PREPARATION DE DERIVES DE LACIDE .alpha.- HYDROXY 2-THIOPHENE ACETIQUE - Google Patents

PROCEDE DE PREPARATION DE DERIVES DE LACIDE .alpha.- HYDROXY 2-THIOPHENE ACETIQUE

Info

Publication number
CA1201443A
CA1201443A CA000435081A CA435081A CA1201443A CA 1201443 A CA1201443 A CA 1201443A CA 000435081 A CA000435081 A CA 000435081A CA 435081 A CA435081 A CA 435081A CA 1201443 A CA1201443 A CA 1201443A
Authority
CA
Canada
Prior art keywords
formula
product
magnesium
iii
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000435081A
Other languages
English (en)
French (fr)
Inventor
Georges Tomasik
Jacques Prost-Marechal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of CA1201443A publication Critical patent/CA1201443A/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA000435081A 1983-04-28 1983-08-22 PROCEDE DE PREPARATION DE DERIVES DE LACIDE .alpha.- HYDROXY 2-THIOPHENE ACETIQUE Expired CA1201443A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8307021A FR2545085B1 (fr) 1983-04-28 1983-04-28 Nouveau procede de preparation de derives de l'acide a-hydroxy 2-thiophene acetique
FR83-07021 1983-04-28

Publications (1)

Publication Number Publication Date
CA1201443A true CA1201443A (fr) 1986-03-04

Family

ID=9288331

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000435081A Expired CA1201443A (fr) 1983-04-28 1983-08-22 PROCEDE DE PREPARATION DE DERIVES DE LACIDE .alpha.- HYDROXY 2-THIOPHENE ACETIQUE

Country Status (22)

Country Link
JP (1) JPS59204185A (de)
KR (1) KR900006558B1 (de)
AT (1) AT392786B (de)
AU (1) AU559749B2 (de)
BE (1) BE897362A (de)
CA (1) CA1201443A (de)
CH (1) CH655316A5 (de)
DE (1) DE3325456A1 (de)
DK (1) DK157493C (de)
ES (1) ES8404345A1 (de)
FI (1) FI832473L (de)
FR (1) FR2545085B1 (de)
GB (1) GB2139215B (de)
HU (1) HU194206B (de)
IE (1) IE55905B1 (de)
IT (1) IT1171855B (de)
LU (1) LU84931A1 (de)
NL (1) NL8302564A (de)
NZ (1) NZ205514A (de)
PT (1) PT77010B (de)
SE (1) SE451018B (de)
ZA (1) ZA835613B (de)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1067828A (fr) * 1951-01-19 1954-06-18 Sterling Drug Inc Perfectionnements relatifs à un procédé de préparation de produits chimiques organiques
GB806710A (en) * 1955-07-05 1958-12-31 Metal & Thermit Corp Reactions of organomagnesium chloride complexes
GB820083A (en) * 1955-07-05 1959-09-16 Metal & Thermit Corp Reactions of organomagnesium chloride reagents
FR2068425B1 (de) * 1969-11-12 1973-01-12 Roussel Uclaf
FR2167334A1 (en) * 1972-01-13 1973-08-24 Roussel Uclaf 4-aroyl-5-alkylthiophene-2-acetic acids - with analgesic and antiinflammatory activity
GB1584120A (en) * 1977-07-21 1981-02-04 Sagami Chem Res Process for the preparation of thiophene derivatives and thiophene derivatives obtained therethrough
GB2030131B (en) * 1978-09-12 1982-12-22 Taiyo Pharma Ind Process for producing 2-(4-(2-thienyl-carbonyl) phenyl) propionic acid
JPS5835145A (ja) * 1981-08-26 1983-03-01 Taisho Pharmaceut Co Ltd α−アリ−ルアルカン酸エステルの製造法

Also Published As

Publication number Publication date
DK157493B (da) 1990-01-15
AT392786B (de) 1991-06-10
DK307583A (da) 1984-10-29
ZA835613B (en) 1985-03-27
ES524648A0 (es) 1984-05-01
NL8302564A (nl) 1984-11-16
SE451018B (sv) 1987-08-24
DE3325456C2 (de) 1993-04-29
KR840008351A (ko) 1984-12-14
ATA286883A (de) 1990-11-15
GB2139215A (en) 1984-11-07
JPS59204185A (ja) 1984-11-19
HU194206B (en) 1988-01-28
PT77010A (fr) 1983-08-01
GB8323492D0 (en) 1983-10-05
IT8348823A0 (it) 1983-08-08
SE8303887D0 (sv) 1983-07-07
KR900006558B1 (ko) 1990-09-13
ES8404345A1 (es) 1984-05-01
DK157493C (da) 1990-06-11
CH655316A5 (fr) 1986-04-15
IE55905B1 (en) 1991-02-14
AU1730983A (en) 1984-11-01
JPH0439469B2 (de) 1992-06-29
BE897362A (fr) 1984-01-25
LU84931A1 (fr) 1984-03-22
DK307583D0 (da) 1983-07-04
FR2545085B1 (fr) 1985-10-25
FR2545085A1 (fr) 1984-11-02
DE3325456A1 (de) 1984-10-31
PT77010B (fr) 1986-04-11
FI832473L (fi) 1984-10-29
AU559749B2 (en) 1987-03-19
NZ205514A (en) 1987-03-31
IE832074L (en) 1984-10-28
IT1171855B (it) 1987-06-10
SE8303887L (sv) 1984-10-29
GB2139215B (en) 1986-10-08
FI832473A0 (fi) 1983-07-05

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Legal Events

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