CA1143656A - Liposome including active substance - Google Patents

Liposome including active substance

Info

Publication number
CA1143656A
CA1143656A CA000351077A CA351077A CA1143656A CA 1143656 A CA1143656 A CA 1143656A CA 000351077 A CA000351077 A CA 000351077A CA 351077 A CA351077 A CA 351077A CA 1143656 A CA1143656 A CA 1143656A
Authority
CA
Canada
Prior art keywords
liposome
active substance
substance
mentioned
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000351077A
Other languages
English (en)
French (fr)
Inventor
Kozyu Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Application granted granted Critical
Publication of CA1143656A publication Critical patent/CA1143656A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
CA000351077A 1979-05-02 1980-05-01 Liposome including active substance Expired CA1143656A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP54283/79 1979-05-02
JP5428379A JPS55153713A (en) 1979-05-02 1979-05-02 Pharmaceutical preparation of ribosome containing active substance

Publications (1)

Publication Number Publication Date
CA1143656A true CA1143656A (en) 1983-03-29

Family

ID=12966226

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000351077A Expired CA1143656A (en) 1979-05-02 1980-05-01 Liposome including active substance

Country Status (5)

Country Link
JP (1) JPS55153713A (de)
CA (1) CA1143656A (de)
DE (1) DE3016976A1 (de)
FR (1) FR2455458A1 (de)
GB (1) GB2050287B (de)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5853755A (en) * 1993-07-28 1998-12-29 Pharmaderm Laboratories Ltd. Biphasic multilamellar lipid vesicles
US7175850B2 (en) 1998-12-23 2007-02-13 Idea Ag Formulation for topical non-invasive application in vivo
US7459171B2 (en) 1999-07-05 2008-12-02 Idea Ag Method for the improvement of transport across adaptable semi-permeable barriers
US7473432B2 (en) 2002-10-11 2009-01-06 Idea Ag NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery
US7867480B1 (en) 1999-01-27 2011-01-11 Gregor Cevc Non-invasive vaccination through the skin
US7927622B1 (en) 1999-01-27 2011-04-19 Gregor Cevc Methods of transnasal transport/immunization with highly adaptable carriers

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4692433A (en) * 1983-10-12 1987-09-08 The Regents Of The University Of California Method and composition for regulating serum calcium levels of mammals
JPS60152410A (ja) * 1984-01-23 1985-08-10 Pola Chem Ind Inc 皮膚外用剤
CH668554A5 (de) * 1984-04-09 1989-01-13 Sandoz Ag Liposomen welche polypeptide mit interleukin-2-aktivitaet enthalten sowie verfahren zu ihrer herstellung.
JPS61100518A (ja) * 1984-10-22 1986-05-19 Ono Pharmaceut Co Ltd ジミリストイルホスフアチジルコリンを主成分とする凍結乾燥されたリポゾ−ム製剤
GB8428222D0 (en) * 1984-11-08 1984-12-19 Bentall R H C Quantifying interaction of induced currents
US5023087A (en) * 1986-02-10 1991-06-11 Liposome Technology, Inc. Efficient method for preparation of prolonged release liposome-based drug delivery system
US4849227A (en) * 1986-03-21 1989-07-18 Eurasiam Laboratories, Inc. Pharmaceutical compositions
ES2068197T3 (es) * 1987-01-27 1995-04-16 Vestar Inc Vehiculo de liberacion a base de fosfolipidos para ingredientes activos insolubles en agua.
US5723147A (en) * 1987-02-23 1998-03-03 Depotech Corporation Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
US5811119A (en) * 1987-05-19 1998-09-22 Board Of Regents, The University Of Texas Formulation and use of carotenoids in treatment of cancer
AU617678B2 (en) * 1987-05-22 1991-12-05 Liposome Company, Inc., The Prostaglandin-lipid formulations
US5262168A (en) * 1987-05-22 1993-11-16 The Liposome Company, Inc. Prostaglandin-lipid formulations
US5925375A (en) * 1987-05-22 1999-07-20 The Liposome Company, Inc. Therapeutic use of multilamellar liposomal prostaglandin formulations
US5811118A (en) * 1987-05-22 1998-09-22 The Liposome Company, Inc. Methods of treatment using unilamellar liposomal arachidonic acid metabolite formulations
SE457933B (sv) * 1987-07-06 1989-02-13 Larsson Kare Farmaceutisk komposition innefattande en vattendispergerad blandning av lipider, monoglycerider och fosfatidylkolin samt dess anvaendning foer framstaellning av en gastronintestinalt verksam kompostion
US5807572A (en) * 1988-02-18 1998-09-15 Depotech Corporation Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
US5422120A (en) * 1988-05-30 1995-06-06 Depotech Corporation Heterovesicular liposomes
GB8822857D0 (en) * 1988-09-29 1988-11-02 Patralan Ltd Pharmaceutical formulations
FR2649610B1 (fr) * 1989-07-13 1994-06-03 Dior Christian Parfums Composition cosmetique ou pharmaceutique et notamment dermatologique contenant de l'ampc ou ses derives en liposomes
DE4005711C1 (de) * 1990-02-23 1991-06-13 A. Nattermann & Cie Gmbh, 5000 Koeln, De
US5556637A (en) * 1990-08-06 1996-09-17 A. Nattermann & Cie. Gmbh Water containing liposome system
DE4108902A1 (de) * 1990-08-06 1992-02-13 Nattermann A & Cie Wasserhaltiges liposomensystem
DE4107153A1 (de) * 1991-03-06 1992-09-10 Gregor Cevc Praeparat zur wirkstoffapplikation in kleinsttroepfchenform
DE4107152C2 (de) * 1991-03-06 1994-03-24 Gregor Cevc Präparate zur nichtinvasiven Verabreichung von Antidiabetica
US6165500A (en) * 1990-08-24 2000-12-26 Idea Ag Preparation for the application of agents in mini-droplets
WO1995001163A1 (fr) * 1992-01-03 1995-01-12 Corbiere Jerome Nouvelles preparations pharmaceutiques a base de peptides pour la voie generale
FR2685868B1 (fr) * 1992-01-03 1995-06-23 Corbiere Jerome Nouvelles preparations pharmaceutiques a base de peptides pour la voie generale.
ATE173615T1 (de) * 1992-01-16 1998-12-15 Univ Texas Formulierung und verwendung von carotenoiden in der krebsbehandlung
IL101241A (en) * 1992-03-16 1997-11-20 Yissum Res Dev Co Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
US5989587A (en) * 1992-10-23 1999-11-23 National Research Council Of Canada Formation of stable liposomes from lipid extracts of archaeobacteria (archaeu)
JPH0657741U (ja) * 1993-01-22 1994-08-12 株式会社村上開明堂 監視機能付きミラー装置
US5455044A (en) * 1993-05-14 1995-10-03 Depotech Corporation Method for treating neurological disorders
IL107471A (en) * 1993-11-02 1997-09-30 Yissum Res Dev Co Pharmaceutical preparation comprising a self- emulsifying formulation and process for its production
BR9408072A (pt) * 1993-11-16 1997-08-12 Depotech Corp Vesículas com liberação controlada de ativos
US5840328A (en) * 1994-01-11 1998-11-24 The Liposome Company, Inc. Treatment using arachidonic acid metabolite and particulate formulations
WO1996004891A1 (en) * 1994-08-08 1996-02-22 Board Of Regents, The University Of Texas System Formulation and use of carotenoids in treatment of cancer
US5993850A (en) * 1994-09-13 1999-11-30 Skyepharma Inc. Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances
WO1996033697A1 (fr) * 1995-04-24 1996-10-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Formulation auto-emulsionnable formant une emulsion huile dans l'eau
US5931809A (en) * 1995-07-14 1999-08-03 Depotech Corporation Epidural administration of therapeutic compounds with sustained rate of release
IL117773A (en) * 1996-04-02 2000-10-31 Pharmos Ltd Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability
US5997899A (en) 1996-10-01 1999-12-07 Skyepharma Inc. Method for producing liposomes with increased percent of compound encapsulated
US6123956A (en) * 1997-07-10 2000-09-26 Keith Baker Methods for universally distributing therapeutic agents to the brain
US6306432B1 (en) 1997-09-08 2001-10-23 Chiron Corporation High and low load formulations of IGF-I in multivesicular liposomes
EP1014946B1 (de) 1997-09-18 2010-04-07 Pacira Pharmaceuticals, Inc. Retardierte freisetzung liposmaler anesthetischer zusammensetzungen.
EP1030652B1 (de) 1997-11-14 2012-04-25 Pacira Pharmaceuticals, Inc. Herstellung von multivesikulären liposomen
US20030068361A1 (en) * 2001-10-09 2003-04-10 Rimona Margalit Liposome-encapsulated insulin formulations
WO2005053643A1 (ja) * 2003-12-01 2005-06-16 Mitsubishi Pharma Corporation リポソーム
WO2011162818A2 (en) * 2010-06-23 2011-12-29 Controlled Nanovolumes, Inc. Lecithin carrier vesicles and methods of making the same
JP2015514683A (ja) * 2012-02-16 2015-05-21 ブライトサイド イノベーションズ,インコーポレイティド 食品性栄養組成物および使用方法
JP6661319B2 (ja) * 2015-09-28 2020-03-11 小林製薬株式会社 リポソーム
TWI658840B (zh) * 2017-05-23 2019-05-11 大江生醫股份有限公司 乳化微脂粒組成物及其製備方法
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3060030A (en) * 1960-04-04 1962-10-23 Carl F Obenauf Lecithinated product
DE2249552A1 (de) * 1971-10-12 1973-05-30 Inchema S A Verfahren zur inkapsulation von insbesondere wasserloeslichen verbindungen
JPS5126213A (ja) * 1974-08-21 1976-03-04 Tanabe Seiyaku Co Johoseibiryushiseizaino seiho
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
CA1119955A (en) * 1978-04-14 1982-03-16 Little (Arthur D.), Inc. Xenobiotic delivery vehicles, method of forming them and method of using them

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5853755A (en) * 1993-07-28 1998-12-29 Pharmaderm Laboratories Ltd. Biphasic multilamellar lipid vesicles
US5993851A (en) * 1993-07-28 1999-11-30 Pharmaderm Laboratories, Ltd. Method for preparing biphasic multilamellar lipid vesicles
US7175850B2 (en) 1998-12-23 2007-02-13 Idea Ag Formulation for topical non-invasive application in vivo
US7867480B1 (en) 1999-01-27 2011-01-11 Gregor Cevc Non-invasive vaccination through the skin
US7927622B1 (en) 1999-01-27 2011-04-19 Gregor Cevc Methods of transnasal transport/immunization with highly adaptable carriers
US7459171B2 (en) 1999-07-05 2008-12-02 Idea Ag Method for the improvement of transport across adaptable semi-permeable barriers
US7591949B2 (en) 1999-07-05 2009-09-22 Idea Ag Method for the improvement of transport across adaptable semi-permeable barriers
US7473432B2 (en) 2002-10-11 2009-01-06 Idea Ag NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery

Also Published As

Publication number Publication date
DE3016976A1 (de) 1980-11-13
JPH0240644B2 (de) 1990-09-12
FR2455458B1 (de) 1983-04-15
FR2455458A1 (fr) 1980-11-28
GB2050287A (en) 1981-01-07
JPS55153713A (en) 1980-11-29
GB2050287B (en) 1983-04-20

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