ATE173615T1 - Formulierung und verwendung von carotenoiden in der krebsbehandlung - Google Patents
Formulierung und verwendung von carotenoiden in der krebsbehandlungInfo
- Publication number
- ATE173615T1 ATE173615T1 AT93903070T AT93903070T ATE173615T1 AT E173615 T1 ATE173615 T1 AT E173615T1 AT 93903070 T AT93903070 T AT 93903070T AT 93903070 T AT93903070 T AT 93903070T AT E173615 T1 ATE173615 T1 AT E173615T1
- Authority
- AT
- Austria
- Prior art keywords
- formulation
- lipid
- carotenoid
- carotenoids
- disclosed
- Prior art date
Links
- 235000021466 carotenoid Nutrition 0.000 title abstract 5
- 150000001747 carotenoids Chemical class 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 150000002632 lipids Chemical class 0.000 abstract 4
- 239000002245 particle Substances 0.000 abstract 2
- 230000005907 cancer growth Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000002687 intercalation Effects 0.000 abstract 1
- 238000009830 intercalation Methods 0.000 abstract 1
- 239000002502 liposome Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82205592A | 1992-01-16 | 1992-01-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE173615T1 true ATE173615T1 (de) | 1998-12-15 |
Family
ID=25235000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93903070T ATE173615T1 (de) | 1992-01-16 | 1993-01-13 | Formulierung und verwendung von carotenoiden in der krebsbehandlung |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0621773B1 (de) |
| JP (2) | JP3691054B2 (de) |
| AT (1) | ATE173615T1 (de) |
| AU (1) | AU3442093A (de) |
| CA (1) | CA2128103C (de) |
| DE (1) | DE69322252T2 (de) |
| ES (1) | ES2128417T3 (de) |
| WO (1) | WO1993013751A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811119A (en) * | 1987-05-19 | 1998-09-22 | Board Of Regents, The University Of Texas | Formulation and use of carotenoids in treatment of cancer |
| EP0689427B1 (de) * | 1993-03-22 | 2002-06-12 | Cognis Australia Pty Ltd | Wasserdispersible therapeutische carotenoid verbindungen |
| DE69424537T2 (de) * | 1993-03-22 | 2001-11-15 | Cognis Australien Pty Ltd | Therapeutischer wirkstoff zur behandlung von melanomen |
| CA2229135A1 (en) * | 1995-08-14 | 1997-02-27 | Oxigene, Inc. | Carotenoid-nicotinamide-zinc compositions and methods of treatment using same |
| WO2001074384A1 (en) * | 2000-03-31 | 2001-10-11 | Aronex Pharmaceuticals, Inc. | Combined interferon alfa and liposomal-encapsulated all-trans retinoic acid, including preparation and use |
| AU2002211776A1 (en) * | 2000-10-17 | 2002-04-29 | Board Of Regents, The University Of Texas System | A method to incorporate n-(4-hydroxyphenyl) retinamide in liposomes |
| US7838513B2 (en) * | 2006-07-07 | 2010-11-23 | Tiltan Pharma Ltd. | Anti-cancer therapy comprising an H2-blocker, at least one antiinflammatory agent and a cytotoxic agent |
| CN107753473A (zh) * | 2016-08-18 | 2018-03-06 | 杭州高田生物医药有限公司 | 一种全反式维甲酸注射剂与应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55153713A (en) * | 1979-05-02 | 1980-11-29 | Kureha Chem Ind Co Ltd | Pharmaceutical preparation of ribosome containing active substance |
| US4918063A (en) * | 1987-02-17 | 1990-04-17 | Board Of Regents, The University Of Texas System | Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract |
| EP0397774A1 (de) * | 1988-02-04 | 1990-11-22 | Board Of Regents, The University Of Texas System | Formulierung und anwendung von retinoiden für behandlung von krebs und anderen krankheiten |
| CA1340241C (en) * | 1988-06-08 | 1998-12-15 | Fountain Pharmaceuticals, Inc. | Method for marking solvent dilution microcarriers |
| DE4005711C1 (de) * | 1990-02-23 | 1991-06-13 | A. Nattermann & Cie Gmbh, 5000 Koeln, De |
-
1993
- 1993-01-13 WO PCT/US1993/000233 patent/WO1993013751A1/en active IP Right Grant
- 1993-01-13 CA CA002128103A patent/CA2128103C/en not_active Expired - Fee Related
- 1993-01-13 DE DE69322252T patent/DE69322252T2/de not_active Expired - Fee Related
- 1993-01-13 EP EP93903070A patent/EP0621773B1/de not_active Expired - Lifetime
- 1993-01-13 ES ES93903070T patent/ES2128417T3/es not_active Expired - Lifetime
- 1993-01-13 JP JP51261893A patent/JP3691054B2/ja not_active Expired - Fee Related
- 1993-01-13 AU AU34420/93A patent/AU3442093A/en not_active Abandoned
- 1993-01-13 AT AT93903070T patent/ATE173615T1/de not_active IP Right Cessation
-
2005
- 2005-03-18 JP JP2005078791A patent/JP2005232182A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE69322252T2 (de) | 1999-08-12 |
| WO1993013751A1 (en) | 1993-07-22 |
| JPH07503014A (ja) | 1995-03-30 |
| EP0621773A1 (de) | 1994-11-02 |
| ES2128417T3 (es) | 1999-05-16 |
| JP2005232182A (ja) | 2005-09-02 |
| DE69322252D1 (de) | 1999-01-07 |
| CA2128103C (en) | 2004-12-28 |
| JP3691054B2 (ja) | 2005-08-31 |
| AU3442093A (en) | 1993-08-03 |
| CA2128103A1 (en) | 1993-07-22 |
| EP0621773B1 (de) | 1998-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |