FR2455458A1 - Liposomes contenant une substance active, notamment un principe actif de medicament - Google Patents

Liposomes contenant une substance active, notamment un principe actif de medicament

Info

Publication number
FR2455458A1
FR2455458A1 FR8009985A FR8009985A FR2455458A1 FR 2455458 A1 FR2455458 A1 FR 2455458A1 FR 8009985 A FR8009985 A FR 8009985A FR 8009985 A FR8009985 A FR 8009985A FR 2455458 A1 FR2455458 A1 FR 2455458A1
Authority
FR
France
Prior art keywords
medicinal product
active substance
active
liposomes containing
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8009985A
Other languages
English (en)
Other versions
FR2455458B1 (fr
Inventor
Kozyu Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Publication of FR2455458A1 publication Critical patent/FR2455458A1/fr
Application granted granted Critical
Publication of FR2455458B1 publication Critical patent/FR2455458B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'INVENTION CONCERNE DES LIPOSOMES CONTENANT UNE SUBSTANCE ACTIVE, NOTAMMENT UN PRINCIPE ACTIF DE MEDICAMENT. ILS COMPRENNENT DES MEMBRANES DE PAROIS FORMEES A PARTIR D'UNE MATIERE DE BASE CONTENANT AU MOINS UN PHOSPHOLIPIDE ET AU MOINS UNE SUBSTANCE HUILEUSE, DE FACON A PRODUIRE DES LIPOSOMES AYANT DES MEMBRANES DE PAROIS DE RESISTANCE ELEVEE ET PERMETTANT UN RETARD A LA LIBERATION IMPORTANT VERS L'EXTERIEUR DE LA SUBSTANCE ACTIVE INCLUSE DANS LEURS VESICULES.
FR8009985A 1979-05-02 1980-05-05 Liposomes contenant une substance active, notamment un principe actif de medicament Granted FR2455458A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5428379A JPS55153713A (en) 1979-05-02 1979-05-02 Pharmaceutical preparation of ribosome containing active substance

Publications (2)

Publication Number Publication Date
FR2455458A1 true FR2455458A1 (fr) 1980-11-28
FR2455458B1 FR2455458B1 (fr) 1983-04-15

Family

ID=12966226

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8009985A Granted FR2455458A1 (fr) 1979-05-02 1980-05-05 Liposomes contenant une substance active, notamment un principe actif de medicament

Country Status (5)

Country Link
JP (1) JPS55153713A (fr)
CA (1) CA1143656A (fr)
DE (1) DE3016976A1 (fr)
FR (1) FR2455458A1 (fr)
GB (1) GB2050287B (fr)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986002846A1 (fr) * 1984-11-08 1986-05-22 Richard Hugh Cameron Bentall Appareil pour reguler la penetration d'une preparation a travers une membrane
EP0233901A1 (fr) * 1985-08-01 1987-09-02 Univ California Procede et composition permettant de regler les niveaux du calcium serique present dans les mammiferes.
EP0280394A1 (fr) * 1987-01-27 1988-08-31 Vestar, Inc. Véhicule de délivrance à base de phospholipides pour des ingrédients actifs insolubles dans l'eau
EP0299937A1 (fr) * 1987-07-06 1989-01-18 LARSSON, Kare Composition basée sur la phosphatidylcholine et des applications médicales de celle-ci
WO1990003164A2 (fr) * 1988-09-29 1990-04-05 Patralan Limited Formulations pharmaceutiques
FR2649610A1 (fr) * 1989-07-13 1991-01-18 Dior Christian Parfums Composition cosmetique ou pharmaceutique et notamment dermatologique contenant de l'ampc ou ses derives en liposomes
WO1991012794A1 (fr) * 1990-02-23 1991-09-05 Nattermann, A. & Cie. Gmbh Dispersion de vesicules phospholipides aqueuse, procede de preparation et utilisation
FR2685868A1 (fr) * 1992-01-03 1993-07-09 Corbiere Jerome Nouvelles preparations pharmaceutiques a base de peptides pour la voie generale.
WO1993013751A1 (fr) * 1992-01-16 1993-07-22 Board Of Regents, The University Of Texas System Formulation a base de carotenoides et utilisation de ces derniers dans le traitement du cancer
EP0630286A1 (fr) * 1992-03-16 1994-12-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Emulsions huile-dans-l'eau de particules chargees positivement
WO1995001163A1 (fr) * 1992-01-03 1995-01-12 Corbiere Jerome Nouvelles preparations pharmaceutiques a base de peptides pour la voie generale
WO1995012384A1 (fr) * 1993-11-02 1995-05-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Formulation auto-emulsionnable formant une huile dans eau
WO1996033697A1 (fr) * 1995-04-24 1996-10-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Formulation auto-emulsionnable formant une emulsion huile dans l'eau
US5811119A (en) * 1987-05-19 1998-09-22 Board Of Regents, The University Of Texas Formulation and use of carotenoids in treatment of cancer
EP1434601A2 (fr) * 2001-10-09 2004-07-07 Aradigm Corporation Preparations d'insuline encapsulees dans des liposomes

Families Citing this family (45)

* Cited by examiner, † Cited by third party
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JPS60152410A (ja) * 1984-01-23 1985-08-10 Pola Chem Ind Inc 皮膚外用剤
CH668554A5 (de) * 1984-04-09 1989-01-13 Sandoz Ag Liposomen welche polypeptide mit interleukin-2-aktivitaet enthalten sowie verfahren zu ihrer herstellung.
JPS61100518A (ja) * 1984-10-22 1986-05-19 Ono Pharmaceut Co Ltd ジミリストイルホスフアチジルコリンを主成分とする凍結乾燥されたリポゾ−ム製剤
US5023087A (en) * 1986-02-10 1991-06-11 Liposome Technology, Inc. Efficient method for preparation of prolonged release liposome-based drug delivery system
US4849227A (en) * 1986-03-21 1989-07-18 Eurasiam Laboratories, Inc. Pharmaceutical compositions
US5723147A (en) * 1987-02-23 1998-03-03 Depotech Corporation Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
US5262168A (en) * 1987-05-22 1993-11-16 The Liposome Company, Inc. Prostaglandin-lipid formulations
US5925375A (en) * 1987-05-22 1999-07-20 The Liposome Company, Inc. Therapeutic use of multilamellar liposomal prostaglandin formulations
AU617678B2 (en) * 1987-05-22 1991-12-05 Liposome Company, Inc., The Prostaglandin-lipid formulations
US5811118A (en) * 1987-05-22 1998-09-22 The Liposome Company, Inc. Methods of treatment using unilamellar liposomal arachidonic acid metabolite formulations
US5807572A (en) * 1988-02-18 1998-09-15 Depotech Corporation Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
US5422120A (en) * 1988-05-30 1995-06-06 Depotech Corporation Heterovesicular liposomes
US5556637A (en) * 1990-08-06 1996-09-17 A. Nattermann & Cie. Gmbh Water containing liposome system
DE4108902A1 (de) * 1990-08-06 1992-02-13 Nattermann A & Cie Wasserhaltiges liposomensystem
DE4107153A1 (de) * 1991-03-06 1992-09-10 Gregor Cevc Praeparat zur wirkstoffapplikation in kleinsttroepfchenform
US6165500A (en) * 1990-08-24 2000-12-26 Idea Ag Preparation for the application of agents in mini-droplets
DE4107152C2 (de) * 1991-03-06 1994-03-24 Gregor Cevc Präparate zur nichtinvasiven Verabreichung von Antidiabetica
US5989587A (en) * 1992-10-23 1999-11-23 National Research Council Of Canada Formation of stable liposomes from lipid extracts of archaeobacteria (archaeu)
JPH0657741U (ja) * 1993-01-22 1994-08-12 株式会社村上開明堂 監視機能付きミラー装置
US5455044A (en) * 1993-05-14 1995-10-03 Depotech Corporation Method for treating neurological disorders
US5853755A (en) * 1993-07-28 1998-12-29 Pharmaderm Laboratories Ltd. Biphasic multilamellar lipid vesicles
PL314485A1 (en) * 1993-11-16 1996-09-16 Depotech Corp Bubbles with controllable release of active substances
US5840328A (en) * 1994-01-11 1998-11-24 The Liposome Company, Inc. Treatment using arachidonic acid metabolite and particulate formulations
AU3361595A (en) * 1994-08-08 1996-03-07 Argus Pharmaceuticals, Inc. Formulation and use of carotenoids in treatment of cancer
US5993850A (en) * 1994-09-13 1999-11-30 Skyepharma Inc. Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances
US5931809A (en) * 1995-07-14 1999-08-03 Depotech Corporation Epidural administration of therapeutic compounds with sustained rate of release
IL117773A (en) * 1996-04-02 2000-10-31 Pharmos Ltd Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability
US5997899A (en) 1996-10-01 1999-12-07 Skyepharma Inc. Method for producing liposomes with increased percent of compound encapsulated
US6123956A (en) * 1997-07-10 2000-09-26 Keith Baker Methods for universally distributing therapeutic agents to the brain
US6306432B1 (en) 1997-09-08 2001-10-23 Chiron Corporation High and low load formulations of IGF-I in multivesicular liposomes
DK1014946T3 (da) 1997-09-18 2010-06-28 Pacira Pharmaceuticals Inc Liposomale anæstetiske sammensætninger med forsinket frigivelse
JP4575592B2 (ja) 1997-11-14 2010-11-04 パシラ ファーマシューティカルズ インコーポレーテッド 多小胞リポソームの製造
ATE272391T1 (de) 1998-12-23 2004-08-15 Idea Ag Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivo
SI1031346T1 (en) 1999-01-27 2002-08-31 Idea Ag Noninvasive vaccination through the skin
EP1031347B1 (fr) 1999-01-27 2002-04-17 Idea Ag Transport/immunisation transnasale avec véhicules très adaptables
MXPA02000053A (es) 1999-07-05 2003-07-21 Idea Ag Un metodo para mejorar el tratamiento a traves de barreras adaptables semipermeables.
US20040105881A1 (en) 2002-10-11 2004-06-03 Gregor Cevc Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
WO2005053643A1 (fr) * 2003-12-01 2005-06-16 Mitsubishi Pharma Corporation Liposome
JP6189749B2 (ja) * 2010-06-23 2017-08-30 ブライトサイド イノベーションズ，インコーポレイティド レシチン担体小胞とその作製方法
US20150182542A1 (en) * 2012-02-16 2015-07-02 Brightside Innovations, Inc. Dietary and nutritional compositions and methods of use
JP6661319B2 (ja) * 2015-09-28 2020-03-11 小林製薬株式会社 リポソーム
CN110536674A (zh) * 2017-05-23 2019-12-03 大江生医股份有限公司 乳化脂质体组合物及其制备方法
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3060030A (en) * 1960-04-04 1962-10-23 Carl F Obenauf Lecithinated product
JPS5126213A (ja) * 1974-08-21 1976-03-04 Tanabe Seiyaku Co Johoseibiryushiseizaino seiho
FR2390159A1 (fr) * 1977-05-10 1978-12-08 Ici Ltd Liposomes et procedes pour les produire

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2249552A1 (de) * 1971-10-12 1973-05-30 Inchema S A Verfahren zur inkapsulation von insbesondere wasserloeslichen verbindungen
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
CA1119955A (fr) * 1978-04-14 1982-03-16 Little (Arthur D.), Inc. Vehicule pour la dispensation de produits xenobiotiques, methode de formation et d'utilisation desdits vehicules

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3060030A (en) * 1960-04-04 1962-10-23 Carl F Obenauf Lecithinated product
JPS5126213A (ja) * 1974-08-21 1976-03-04 Tanabe Seiyaku Co Johoseibiryushiseizaino seiho
FR2390159A1 (fr) * 1977-05-10 1978-12-08 Ici Ltd Liposomes et procedes pour les produire

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1976 *

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986002846A1 (fr) * 1984-11-08 1986-05-22 Richard Hugh Cameron Bentall Appareil pour reguler la penetration d'une preparation a travers une membrane
EP0233901A1 (fr) * 1985-08-01 1987-09-02 Univ California Procede et composition permettant de regler les niveaux du calcium serique present dans les mammiferes.
EP0233901A4 (fr) * 1985-08-01 1988-09-07 Univ California Procede et composition permettant de regler les niveaux du calcium serique present dans les mammiferes.
EP0280394A1 (fr) * 1987-01-27 1988-08-31 Vestar, Inc. Véhicule de délivrance à base de phospholipides pour des ingrédients actifs insolubles dans l'eau
US6200597B1 (en) * 1987-05-19 2001-03-13 Board Of Regents, The University Of Texas System Formulation and use of carotenoids in treatment of cancer
US5811119A (en) * 1987-05-19 1998-09-22 Board Of Regents, The University Of Texas Formulation and use of carotenoids in treatment of cancer
EP0299937A1 (fr) * 1987-07-06 1989-01-18 LARSSON, Kare Composition basée sur la phosphatidylcholine et des applications médicales de celle-ci
EP0366277A2 (fr) * 1988-09-29 1990-05-02 Patralan Limited Formulations pharmaceutiques
EP0366277A3 (en) * 1988-09-29 1990-11-28 Patralan Limited Pharmaceutical formulations
WO1990003164A3 (fr) * 1988-09-29 1990-06-14 Patralan Ltd Formulations pharmaceutiques
WO1990003164A2 (fr) * 1988-09-29 1990-04-05 Patralan Limited Formulations pharmaceutiques
FR2649610A1 (fr) * 1989-07-13 1991-01-18 Dior Christian Parfums Composition cosmetique ou pharmaceutique et notamment dermatologique contenant de l'ampc ou ses derives en liposomes
WO1991000726A1 (fr) * 1989-07-13 1991-01-24 Parfums Christian Dior UTILISATION D'AMPc OU SES DERIVES POUR LA PREPARATION DE COMPOSITIONS COSMETIQUE OU PHARMACEUTIQUE
WO1991012794A1 (fr) * 1990-02-23 1991-09-05 Nattermann, A. & Cie. Gmbh Dispersion de vesicules phospholipides aqueuse, procede de preparation et utilisation
FR2685868A1 (fr) * 1992-01-03 1993-07-09 Corbiere Jerome Nouvelles preparations pharmaceutiques a base de peptides pour la voie generale.
WO1995001163A1 (fr) * 1992-01-03 1995-01-12 Corbiere Jerome Nouvelles preparations pharmaceutiques a base de peptides pour la voie generale
WO1993013751A1 (fr) * 1992-01-16 1993-07-22 Board Of Regents, The University Of Texas System Formulation a base de carotenoides et utilisation de ces derniers dans le traitement du cancer
EP0630286A4 (fr) * 1992-03-16 1995-06-07 Yissum Res Dev Co Emulsions huile-dans-l'eau de particules chargees positivement.
EP0630286A1 (fr) * 1992-03-16 1994-12-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Emulsions huile-dans-l'eau de particules chargees positivement
US6007826A (en) * 1992-03-16 1999-12-28 Yisum Research Development Company Of The Hebrew University Of Jerusalem Oil-in-water emulsions of positively charged particles
WO1995012384A1 (fr) * 1993-11-02 1995-05-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Formulation auto-emulsionnable formant une huile dans eau
WO1996033697A1 (fr) * 1995-04-24 1996-10-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Formulation auto-emulsionnable formant une emulsion huile dans l'eau
AU692255B2 (en) * 1995-04-24 1998-06-04 Yissum Research Development Company Of The Hebrew University Of Jerusalem Self-emulsifiable formulation producing an oil-in-water emulsion
EP1434601A2 (fr) * 2001-10-09 2004-07-07 Aradigm Corporation Preparations d'insuline encapsulees dans des liposomes
EP1434601A4 (fr) * 2001-10-09 2009-08-19 Aradigm Corp Preparations d'insuline encapsulees dans des liposomes

Also Published As

Publication number Publication date
CA1143656A (fr) 1983-03-29
FR2455458B1 (fr) 1983-04-15
DE3016976A1 (de) 1980-11-13
GB2050287A (en) 1981-01-07
JPS55153713A (en) 1980-11-29
JPH0240644B2 (fr) 1990-09-12
GB2050287B (en) 1983-04-20

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