ATE272391T1 - Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivo - Google Patents
Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivoInfo
- Publication number
- ATE272391T1 ATE272391T1 AT98966846T AT98966846T ATE272391T1 AT E272391 T1 ATE272391 T1 AT E272391T1 AT 98966846 T AT98966846 T AT 98966846T AT 98966846 T AT98966846 T AT 98966846T AT E272391 T1 ATE272391 T1 AT E272391T1
- Authority
- AT
- Austria
- Prior art keywords
- formulation
- less
- pores
- amount
- case
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 5
- 230000000699 topical effect Effects 0.000 title 1
- 239000011148 porous material Substances 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 241000305071 Enterobacterales Species 0.000 abstract 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 abstract 1
- 241000191967 Staphylococcus aureus Species 0.000 abstract 1
- 241001148470 aerobic bacillus Species 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 244000052616 bacterial pathogen Species 0.000 abstract 1
- 230000004888 barrier function Effects 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 230000003641 microbiacidal effect Effects 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 230000000149 penetrating effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Toxicology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP1998/008421 WO2000038653A1 (en) | 1998-12-23 | 1998-12-23 | Improved formulation for topical non-invasive application in vivo |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE272391T1 true ATE272391T1 (de) | 2004-08-15 |
Family
ID=8167168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98966846T ATE272391T1 (de) | 1998-12-23 | 1998-12-23 | Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivo |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US7175850B2 (de) |
| EP (1) | EP1140021B1 (de) |
| JP (1) | JP2002533379A (de) |
| KR (1) | KR100638150B1 (de) |
| CN (1) | CN1320880C (de) |
| AT (1) | ATE272391T1 (de) |
| AU (1) | AU770803B2 (de) |
| BR (1) | BR9816113A (de) |
| CA (1) | CA2356080C (de) |
| CZ (1) | CZ20012038A3 (de) |
| DE (1) | DE69825495T2 (de) |
| EE (1) | EE200100342A (de) |
| ES (1) | ES2226203T3 (de) |
| HK (1) | HK1040629B (de) |
| HR (1) | HRP20010309B1 (de) |
| HU (1) | HUP0104424A3 (de) |
| MX (1) | MXPA01006424A (de) |
| NO (1) | NO20013164L (de) |
| PL (1) | PL193824B1 (de) |
| RU (1) | RU2207844C2 (de) |
| TR (1) | TR200101790T2 (de) |
| WO (1) | WO2000038653A1 (de) |
Families Citing this family (118)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020048596A1 (en) * | 1994-12-30 | 2002-04-25 | Gregor Cevc | Preparation for the transport of an active substance across barriers |
| CN1192766C (zh) * | 1998-10-23 | 2005-03-16 | 伊迪亚股份公司 | 开发、测试和使用用于改进的有效负载和可控制性解缔/缔合速度的大分子和复合聚集体的缔合物的方法 |
| ATE272391T1 (de) * | 1998-12-23 | 2004-08-15 | Idea Ag | Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivo |
| SI1031346T1 (en) | 1999-01-27 | 2002-08-31 | Idea Ag | Noninvasive vaccination through the skin |
| ES2173679T3 (es) | 1999-01-27 | 2002-10-16 | Idea Ag | Inmunizacion/transporte transnasal con vehiculos altamente adaptables. |
| MXPA02000053A (es) | 1999-07-05 | 2003-07-21 | Idea Ag | Un metodo para mejorar el tratamiento a traves de barreras adaptables semipermeables. |
| US20030077301A1 (en) * | 1999-12-16 | 2003-04-24 | Maibach Howard I. | Topical pharmaceutical composition for the treatment of inflammatory dermatoses |
| WO2002007767A2 (en) * | 2000-07-26 | 2002-01-31 | Alcon Universal Ltd. | Pharmaceutical suspension compositions lacking a polymeric suspending agent |
| ES2260321T3 (es) | 2000-12-07 | 2006-11-01 | Universiteit Utrecht Holding B.V. | Composicion para el tratamiento de transtornos inflamatorios. |
| US8246969B2 (en) | 2001-11-16 | 2012-08-21 | Skinmedica, Inc. | Compositions containing aromatic aldehydes and their use in treatments |
| US7763663B2 (en) | 2001-12-19 | 2010-07-27 | University Of Massachusetts | Polysaccharide-containing block copolymer particles and uses thereof |
| CA2476859C (en) * | 2002-03-13 | 2011-09-20 | Collagenex Pharmaceuticals, Inc. | Water-based delivery systems |
| US8367098B2 (en) | 2002-04-30 | 2013-02-05 | The Population Council, Inc. | Unique combinations of antimicrobial compositions |
| EP1371362A1 (de) * | 2002-06-12 | 2003-12-17 | Universiteit Utrecht Holding B.V. | Zusammensetzung zur Behandlung entzündlicher Erkrankungen |
| EP1539193A4 (de) * | 2002-07-03 | 2010-05-05 | Pericor Science Inc | Zusammensetzungen von hyaluronsäure und verwendungsverfahren |
| US7473432B2 (en) * | 2002-10-11 | 2009-01-06 | Idea Ag | NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery |
| JP2006505619A (ja) * | 2002-10-11 | 2006-02-16 | アイディーイーエー アーゲー | 半透性バリアを介した向上した輸送のための、およびインビボでの、特に皮膚を介した非侵襲性薬剤利用のための、少なくとも3つの両親媒性物質を含む、向上した変形性を備えた凝集体 |
| US7323443B2 (en) | 2002-12-12 | 2008-01-29 | Agennix Inc. | Lactoferrin in the reduction of pain |
| RU2233163C1 (ru) * | 2003-04-30 | 2004-07-27 | Государственное учреждение "Нижегородский научно-исследовательский кожно-венерологический институт" | Способ лечения акантолитической пузырчатки |
| US7034126B2 (en) * | 2003-05-14 | 2006-04-25 | Agennix, Inc. | Lactoferrin in the treatment of diabetes mellitus |
| NZ546073A (en) * | 2003-09-22 | 2009-07-31 | Innovation Technologies Inc | Wound irrigation device and method |
| FR2861304B1 (fr) * | 2003-10-23 | 2008-07-18 | Univ Grenoble 1 | Modulateurs des canaux cftr |
| US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| US8092788B2 (en) | 2004-03-03 | 2012-01-10 | Revance Therapeutics, Inc. | Compositions and methods for topical diagnostic and therapeutic transport |
| NZ549817A (en) * | 2004-03-22 | 2010-06-25 | Besins Int Lab | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| EP1755616B1 (de) * | 2004-04-08 | 2013-08-14 | Advanced Ocular Systems Limited | Behandlung von exsudativer Retinopathie mit Mineralcorticoiden |
| KR100772327B1 (ko) * | 2004-04-22 | 2007-10-31 | 주식회사유한양행 | 하이드로코티손 또는 그 염을 함유하는 나노에멀젼 조성물 |
| DE102004021992A1 (de) * | 2004-05-03 | 2005-11-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Topische Zubereitung enthaltend Ambroxol |
| US20050255154A1 (en) | 2004-05-11 | 2005-11-17 | Lena Pereswetoff-Morath | Method and composition for treating rhinitis |
| BRPI0515888A (pt) * | 2004-09-24 | 2008-08-12 | Lipo Chemicals Inc | sistema de liberação, composição para aplicação tópica em pele ou pêlo de mamìfero, e, método para tratar pele de mamìfero |
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| BRPI0519445A2 (pt) * | 2005-01-14 | 2009-01-20 | Lipo Chemicals Inc | composiÇço, formulaÇço de cuidado da pele, mÉtodos para tratar peles de humano e de memÍfero, para prevenir pele de mamÍfero hiperpigmentada, e para praparar uma composiÇço de clareamento da pele |
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| EP1888033B1 (de) | 2005-06-09 | 2014-02-19 | Meda AB | Verfahren und zusammensetzung zur behandlung von entzündlichen erkrankungen |
| JP5368793B2 (ja) | 2005-07-18 | 2013-12-18 | ユニバーシティ オブ マサチューセッツ ロウエル | ナノエマルジョンを製造および使用するための組成物および方法 |
| CA2880727C (en) | 2005-08-31 | 2019-05-07 | Neil P. Desai | Compositions comprising poorly water soluble pharmaceutical agents and antimicrobial agents |
| KR101643416B1 (ko) * | 2005-08-31 | 2016-07-27 | 아브락시스 바이오사이언스, 엘엘씨 | 증가된 안정성을 가진 수 난용성 약물의 조성물 및 제조방법 |
| CN101257891A (zh) * | 2005-09-01 | 2008-09-03 | 比奥里波克斯公司 | 包含抗组胺剂以及皮质类固醇的脂质体组合物及其在制备治疗鼻炎以及相关疾病的药物中的用途 |
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| US9642912B2 (en) | 2006-03-06 | 2017-05-09 | Crescita Therapeutics Inc. | Topical formulations for treating skin conditions |
| US7767217B2 (en) * | 2006-03-14 | 2010-08-03 | Foresight Biotherapeutics | Ophthalmic compositions comprising povidone-iodine |
| WO2008020042A1 (en) * | 2006-08-16 | 2008-02-21 | Action Medicines, S.L. | Use of 2, 5-dihydroxybenzene derivatives for the treatment of tissue reactive diseases |
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- 1998-12-23 HK HK02102230.4A patent/HK1040629B/en not_active IP Right Cessation
- 1998-12-23 EP EP98966846A patent/EP1140021B1/de not_active Revoked
- 1998-12-23 JP JP2000590607A patent/JP2002533379A/ja active Pending
- 1998-12-23 HR HR20010309A patent/HRP20010309B1/xx not_active IP Right Cessation
- 1998-12-23 AU AU25137/99A patent/AU770803B2/en not_active Ceased
- 1998-12-23 WO PCT/EP1998/008421 patent/WO2000038653A1/en not_active Ceased
- 1998-12-23 HU HU0104424A patent/HUP0104424A3/hu unknown
- 1998-12-23 KR KR1020017006708A patent/KR100638150B1/ko not_active Expired - Fee Related
- 1998-12-23 PL PL98349467A patent/PL193824B1/pl not_active IP Right Cessation
- 1998-12-23 DE DE69825495T patent/DE69825495T2/de not_active Expired - Lifetime
- 1998-12-23 MX MXPA01006424A patent/MXPA01006424A/es not_active IP Right Cessation
- 1998-12-23 CN CNB988143690A patent/CN1320880C/zh not_active Expired - Fee Related
- 1998-12-23 CA CA002356080A patent/CA2356080C/en not_active Expired - Fee Related
- 1998-12-23 EE EEP200100342A patent/EE200100342A/xx unknown
- 1998-12-23 RU RU2001120008/14A patent/RU2207844C2/ru not_active IP Right Cessation
- 1998-12-23 CZ CZ20012038A patent/CZ20012038A3/cs unknown
- 1998-12-23 BR BR9816113-0A patent/BR9816113A/pt not_active Application Discontinuation
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2001
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2006
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