IL107471A - Pharmaceutical preparation comprising a self- emulsifying formulation and process for its production - Google Patents

Pharmaceutical preparation comprising a self- emulsifying formulation and process for its production

Info

Publication number
IL107471A
IL107471A IL107471A IL10747193A IL107471A IL 107471 A IL107471 A IL 107471A IL 107471 A IL107471 A IL 107471A IL 10747193 A IL10747193 A IL 10747193A IL 107471 A IL107471 A IL 107471A
Authority
IL
Israel
Prior art keywords
self
oil
production
pharmaceutical preparation
seof
Prior art date
Application number
IL107471A
Other versions
IL107471A0 (en
Inventor
Simon Benita
Tanya Gershanik
Jakie Kleinstern
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Priority to IL107471A priority Critical patent/IL107471A/en
Publication of IL107471A0 publication Critical patent/IL107471A0/en
Priority to DK95900161T priority patent/DK0726760T3/en
Priority to DE69418892T priority patent/DE69418892T2/en
Priority to AT95900161T priority patent/ATE180666T1/en
Priority to EP95900161A priority patent/EP0726760B1/en
Priority to ES95900161T priority patent/ES2135034T3/en
Priority to PCT/FR1994/001239 priority patent/WO1995012384A1/en
Publication of IL107471A publication Critical patent/IL107471A/en
Priority to GR990402226T priority patent/GR3031141T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

The self-emulsible oil formulation (SEOF) contains an oil component and a surfactant. The SEOF is characterized in that the oil component contains an oil vector and a cationic lipid and, optionally, a lipophilic oily fatty alcohol. The oil-in-water emulsion which is formed by the mixing of the SEOF has oily droplets which are positively charged.
IL107471A 1993-11-02 1993-11-02 Pharmaceutical preparation comprising a self- emulsifying formulation and process for its production IL107471A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IL107471A IL107471A (en) 1993-11-02 1993-11-02 Pharmaceutical preparation comprising a self- emulsifying formulation and process for its production
DK95900161T DK0726760T3 (en) 1993-11-02 1994-10-25 Self-emulsifiable formulation which forms an oil-in-water emulsion
DE69418892T DE69418892T2 (en) 1993-11-02 1994-10-25 SELF-TEMPERATURE FORMULATION FOR THE FORMATION OF AN OIL-IN-WATER EMULSION
AT95900161T ATE180666T1 (en) 1993-11-02 1994-10-25 SELF-EMULSIFYING FORMULATION TO FORM AN OIL-IN-WATER EMULSION
EP95900161A EP0726760B1 (en) 1993-11-02 1994-10-25 Self-emulsible formulation forming an oil-in-water emulsion
ES95900161T ES2135034T3 (en) 1993-11-02 1994-10-25 SELF-EMULSING FORMULATION FORMING AN OIL-IN-WATER EMULSION.
PCT/FR1994/001239 WO1995012384A1 (en) 1993-11-02 1994-10-25 Self-emulsible formulation forming an oil-in-water emulsion
GR990402226T GR3031141T3 (en) 1993-11-02 1999-09-02 Self-emulsible formulation forming an oil-in-water emulsion

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL107471A IL107471A (en) 1993-11-02 1993-11-02 Pharmaceutical preparation comprising a self- emulsifying formulation and process for its production

Publications (2)

Publication Number Publication Date
IL107471A0 IL107471A0 (en) 1994-02-27
IL107471A true IL107471A (en) 1997-09-30

Family

ID=11065403

Family Applications (1)

Application Number Title Priority Date Filing Date
IL107471A IL107471A (en) 1993-11-02 1993-11-02 Pharmaceutical preparation comprising a self- emulsifying formulation and process for its production

Country Status (8)

Country Link
EP (1) EP0726760B1 (en)
AT (1) ATE180666T1 (en)
DE (1) DE69418892T2 (en)
DK (1) DK0726760T3 (en)
ES (1) ES2135034T3 (en)
GR (1) GR3031141T3 (en)
IL (1) IL107471A (en)
WO (1) WO1995012384A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586003B2 (en) 1995-09-26 2003-07-01 University Of Pittsburgh Emulsion and micellar formulations for the delivery of biologically active substances to cells

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996033697A1 (en) * 1995-04-24 1996-10-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Self-emulsifiable formulation producing an oil-in-water emulsion
JP2002513750A (en) * 1998-05-07 2002-05-14 エラン コーポレーシヨン ピーエルシー Solvent / co-solvent free microemulsion and emulsion pre-concentrate drug delivery system
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1090703B (en) * 1976-12-03 1985-06-26 Scherer Ltd R P IMPROVEMENT IN USEFUL COMPOSITIONS SUCH AS DRUG VEHICLES
JPS55153713A (en) * 1979-05-02 1980-11-29 Kureha Chem Ind Co Ltd Pharmaceutical preparation of ribosome containing active substance
JP2847783B2 (en) * 1988-08-11 1999-01-20 日清製粉株式会社 Anticancer activity enhancer
US5084087A (en) * 1989-04-26 1992-01-28 Basf Corporation Ready to dilute adjuvant-containing postemergent herbicide formulations
JPH0395118A (en) * 1989-09-07 1991-04-19 Green Cross Corp:The Prostaglandin-containing liposome preparation
EP0626850B1 (en) * 1992-02-18 2002-05-15 Pharmos Corporation Dry compositions for preparing submicron emulsions
IL101241A (en) * 1992-03-16 1997-11-20 Yissum Res Dev Co Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586003B2 (en) 1995-09-26 2003-07-01 University Of Pittsburgh Emulsion and micellar formulations for the delivery of biologically active substances to cells

Also Published As

Publication number Publication date
ES2135034T3 (en) 1999-10-16
DE69418892T2 (en) 1999-12-23
EP0726760B1 (en) 1999-06-02
GR3031141T3 (en) 1999-12-31
EP0726760A1 (en) 1996-08-21
ATE180666T1 (en) 1999-06-15
IL107471A0 (en) 1994-02-27
DK0726760T3 (en) 1999-12-13
DE69418892D1 (en) 1999-07-08
WO1995012384A1 (en) 1995-05-11

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees