BRPI0925048B8 - módulo para produção de comprimidos e método para a produção contínua de comprimidos - Google Patents
módulo para produção de comprimidos e método para a produção contínua de comprimidosInfo
- Publication number
- BRPI0925048B8 BRPI0925048B8 BRPI0925048A BRPI0925048A BRPI0925048B8 BR PI0925048 B8 BRPI0925048 B8 BR PI0925048B8 BR PI0925048 A BRPI0925048 A BR PI0925048A BR PI0925048 A BRPI0925048 A BR PI0925048A BR PI0925048 B8 BRPI0925048 B8 BR PI0925048B8
- Authority
- BR
- Brazil
- Prior art keywords
- tablet press
- module
- tablet production
- tablet
- outlet
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B13/00—Conditioning or physical treatment of the material to be shaped
- B29B13/06—Conditioning or physical treatment of the material to be shaped by drying
- B29B13/065—Conditioning or physical treatment of the material to be shaped by drying of powder or pellets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B7/00—Mixing; Kneading
- B29B7/30—Mixing; Kneading continuous, with mechanical mixing or kneading devices
- B29B7/34—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices
- B29B7/38—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary
- B29B7/46—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft
- B29B7/48—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft with intermeshing devices, e.g. screws
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B7/00—Mixing; Kneading
- B29B7/30—Mixing; Kneading continuous, with mechanical mixing or kneading devices
- B29B7/58—Component parts, details or accessories; Auxiliary operations
- B29B7/72—Measuring, controlling or regulating
- B29B7/726—Measuring properties of mixture, e.g. temperature or density
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/02—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/32—Component parts, details or accessories; Auxiliary operations
- B29C43/34—Feeding the material to the mould or the compression means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/32—Component parts, details or accessories; Auxiliary operations
- B29C43/50—Removing moulded articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/32—Component parts, details or accessories; Auxiliary operations
- B29C43/58—Measuring, controlling or regulating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/005—Control arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
- B30B15/30—Feeding material to presses
- B30B15/302—Feeding material in particulate or plastic state to moulding presses
- B30B15/308—Feeding material in particulate or plastic state to moulding presses in a continuous manner, e.g. for roller presses, screw extrusion presses
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/32—Component parts, details or accessories; Auxiliary operations
- B29C43/58—Measuring, controlling or regulating
- B29C2043/5833—Measuring, controlling or regulating movement of moulds or mould parts, e.g. opening or closing, actuating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0005—Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
- B29K2105/0035—Medical or pharmaceutical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/25—Solid
- B29K2105/251—Particles, powder or granules
Abstract
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IB2009/051885 WO2010128359A1 (en) | 2009-05-07 | 2009-05-07 | Tablet production module and method for continuous production of tablets |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0925048A2 BRPI0925048A2 (pt) | 2015-08-04 |
BRPI0925048B1 BRPI0925048B1 (pt) | 2019-07-09 |
BRPI0925048B8 true BRPI0925048B8 (pt) | 2021-06-22 |
Family
ID=41479620
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0925048A BRPI0925048B8 (pt) | 2009-05-07 | 2009-05-07 | módulo para produção de comprimidos e método para a produção contínua de comprimidos |
Country Status (10)
Country | Link |
---|---|
US (2) | US9713575B2 (pt) |
EP (1) | EP2427166B1 (pt) |
JP (1) | JP2012525895A (pt) |
CN (1) | CN102438578A (pt) |
BR (1) | BRPI0925048B8 (pt) |
DK (1) | DK2427166T3 (pt) |
ES (1) | ES2441446T3 (pt) |
HR (1) | HRP20131155T1 (pt) |
PT (1) | PT2427166E (pt) |
WO (1) | WO2010128359A1 (pt) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE032640T2 (en) | 2005-11-08 | 2017-10-30 | Vertex Pharma | Heterocyclic modulator of ATP-binding cassette transcripts |
US8969386B2 (en) | 2007-05-09 | 2015-03-03 | Vertex Pharmaceuticals Incorporated | Modulators of CFTR |
CN101910134B (zh) | 2007-12-07 | 2014-03-19 | 沃泰克斯药物股份有限公司 | 环烷基甲酰氨基-吡啶苯甲酸类的生产方法 |
US8507534B2 (en) | 2007-12-07 | 2013-08-13 | Vertex Pharmaceuticals Incorporated | Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid |
CN103382201B (zh) | 2008-02-28 | 2016-12-28 | 沃泰克斯药物股份有限公司 | 作为cftr调节剂的杂芳基衍生物 |
JP2013523833A (ja) | 2010-04-07 | 2013-06-17 | バーテックス ファーマシューティカルズ インコーポレイテッド | 3−(6−(1−(2,2−ジフルオロベンゾ[d][1,3]ジオキソール−5−イル)シクロプロパンカルボキサミド)−3−メチルピリジン−2−イル)安息香酸の医薬組成物およびその投与 |
CA3128556A1 (en) * | 2012-01-25 | 2013-08-01 | Vertex Pharmaceuticals Incorporated | Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid |
WO2013182870A1 (en) | 2012-06-04 | 2013-12-12 | Gea Process Engineering Nv | Feeder module and method for providing a mixture of one or more powders to a receiving container |
WO2013182869A1 (en) | 2012-06-04 | 2013-12-12 | Gea Process Engineering Nv | Feeder unit, a feeder module comprising a plurality of feeder units, and method for discharging a constant mass flow of one or more powders into a receiving container |
EP3013571B1 (en) * | 2013-06-27 | 2023-06-07 | GEA Process Engineering nv | Method for continuous production of tablets, tabletting system for carrying out the method, and use of the tabletting system for the production of tablets of at least two ingredients containing particles with a significant difference in particle size |
US10260807B2 (en) | 2013-07-05 | 2019-04-16 | Freund Corporation | Drying device and continuous granule production system |
WO2015073231A1 (en) * | 2013-11-12 | 2015-05-21 | Vertex Pharmaceuticals Incorporated | Process of preparing pharmaceutical compositions for the treatment of cftr mediated diseases |
KR102482164B1 (ko) | 2014-08-15 | 2022-12-29 | 메사추세츠 인스티튜트 오브 테크놀로지 | 활성 제약 성분을 포함한 화학적 생성물의 합성을 위한 시스템 및 방법 |
SI3221692T1 (sl) | 2014-11-18 | 2021-11-30 | Vertex Pharmaceuticals Inc. | Postopek za izvajanje testov visoke prepustnosti z visoko zmogljivostno tekočinsko kromatografijo |
JP6606747B2 (ja) * | 2015-06-15 | 2019-11-20 | 株式会社菊水製作所 | 粉体混合供給装置及びこれを用いた粉体圧縮成形機 |
DE102015116565B4 (de) | 2015-09-30 | 2018-03-01 | Fette Compacting Gmbh | Verfahren zum Betreiben einer Rundläufer-Tablettenpresse und Rundläufer-Tablettenpresse |
WO2017156420A1 (en) | 2016-03-10 | 2017-09-14 | Lonza Ltd | Customizable facility |
US10689873B2 (en) | 2016-03-10 | 2020-06-23 | Lonza Ltd | Customizable facility |
JP6681756B2 (ja) * | 2016-03-16 | 2020-04-15 | 株式会社菊水製作所 | 回転式粉体圧縮成形機の制御装置 |
JP6775311B2 (ja) * | 2016-03-29 | 2020-10-28 | 株式会社菊水製作所 | 成形品製造システム |
JP6752034B2 (ja) * | 2016-03-29 | 2020-09-09 | 株式会社菊水製作所 | 粉体混合度測定装置、粉体混合供給システム、圧縮成形品を製造する方法 |
JP6681764B2 (ja) * | 2016-03-29 | 2020-04-15 | 株式会社菊水製作所 | 成形品製造システム |
US11185839B2 (en) | 2016-05-02 | 2021-11-30 | Massachusetts Institute Of Technology | Reconfigurable multi-step chemical synthesis system and related components and methods |
WO2018004321A1 (ko) * | 2016-07-01 | 2018-01-04 | 재단법인 의약바이오컨버젼스연구단 | 아미노아실 티알엔에이 중합효소 관련 단백질 발현 수준을 이용한 갑상선 여포암 진단용 조성물과 진단 마커 검출 방법 |
JP7116975B2 (ja) * | 2016-08-31 | 2022-08-12 | フロイント産業株式会社 | 逸脱処理装置及び逸脱処理方法 |
DE102016218135A1 (de) | 2016-09-21 | 2018-03-22 | Robert Bosch Gmbh | Produktionsmodul zum Herstellen fester Arzneiformen |
US10875217B2 (en) * | 2016-12-12 | 2020-12-29 | Kikusui Seisakusho Ltd. | Controller and control method for rotary compression-molding machine |
EP3582741B1 (en) | 2017-02-17 | 2023-07-26 | Massachusetts Institute of Technology | Systems and methods for the fabrication of tablets, including pharmaceutical tablets |
EP3450126A1 (en) | 2017-09-01 | 2019-03-06 | Hexion Research Belgium SA | Multi-component mixing and metering equipment with online stoichiometry control |
CN111278404B (zh) * | 2017-09-21 | 2023-05-09 | 豪夫迈·罗氏有限公司 | 制药设施和药物产品的制造方法 |
JP7224612B2 (ja) * | 2017-10-06 | 2023-02-20 | 株式会社菊水製作所 | 成形品処理システム |
CN109902892A (zh) * | 2017-12-08 | 2019-06-18 | 中国石油化工股份有限公司 | 基于流程标签的安全责任制优化方法 |
EP3757566A4 (en) * | 2018-02-22 | 2021-09-08 | Mitsubishi Chemical Engineering Corporation | CONTINUOUS MANUFACTURING SYSTEM AND METHOD |
JP2019154862A (ja) * | 2018-03-14 | 2019-09-19 | 清水建設株式会社 | 連続式製剤装置及び連続式製剤方法 |
JP2018183817A (ja) * | 2018-06-20 | 2018-11-22 | ヘーエーアー プロセス エンジニアリング ナームロゼ フェンノートシャップ | 錠剤の連続生産のための方法と、この方法を実行するための錠剤成形システムと、粒径が大きく異なる粒子を含む少なくとも2つの成分の錠剤を生産するためのこの錠剤成形システムの使用 |
GB2578272B (en) * | 2018-07-10 | 2023-03-29 | Innopharma Res Limited | Apparatus and method for the production of solid dosage forms |
PL3833964T3 (pl) * | 2018-08-07 | 2023-09-04 | Norton (Waterford) Limited | Zastosowanie spektroskopii ramana do produkcji proszków do inhalacji |
CA3125779A1 (en) * | 2019-01-07 | 2020-07-16 | Fritz Schmitt | Process for producing a gaseous active ingredient or a gaseous active ingredient mixture, kit for use therein and gaseous composition |
JP7300708B2 (ja) * | 2019-04-01 | 2023-06-30 | 株式会社菊水製作所 | 粉体を用いる処理システム及びその制御方法 |
EP3756640A1 (en) | 2019-06-26 | 2020-12-30 | Fette Compacting GmbH | System and method for continuous production of solid dosage forms |
DE102019218379A1 (de) | 2019-11-27 | 2021-05-27 | Glatt Ingenieurtechnik Gesellschaft mit beschränkter Haftung | Modulare Anlage und Verfahren zur Herstellung von Arzneiformschüttgut |
DE102020115777A1 (de) * | 2020-06-16 | 2021-12-16 | Fette Compacting Gmbh | Verfahren zur Produktverfolgung in einer Anlage |
EP4005663A1 (en) | 2020-11-26 | 2022-06-01 | Fette Compacting GmbH | Powder blender for a system for continuous processing of powder products |
EP4005764A1 (en) | 2020-11-26 | 2022-06-01 | Fette Compacting GmbH | Feeding and blending system for a system for continuous processing of powder products |
Family Cites Families (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61133131A (ja) | 1984-11-29 | 1986-06-20 | Kyowa Hakko Kogyo Co Ltd | 粉粒体定量供給混合装置付き圧縮成型機 |
DK196786A (da) | 1986-04-29 | 1987-10-30 | Ebbe Busch Larsen | Fremgangsmoede og middel til styring af et foderblandingsanlaeg |
IE873172L (en) * | 1986-12-29 | 1988-06-29 | Harvard College | Continuous process for producing a comestible tablet |
GB9004781D0 (en) | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
JPH0434445A (ja) | 1990-05-30 | 1992-02-05 | Ricoh Co Ltd | 電子写真装置 |
JPH066148B2 (ja) * | 1991-01-16 | 1994-01-26 | 株式会社菊水製作所 | 回転式粉末成形機における減圧下打錠錠剤の点検方法及びその装置 |
DE4315680C2 (de) | 1993-05-05 | 1996-02-29 | Korsch Maschfab | Regelung von Tablettenparametern bei der Herstellung auf Rundlauf-Pressen |
DE4342962C1 (de) | 1993-12-16 | 1995-02-02 | Buck Chem Tech Werke | Vorrichtung zum Kuppeln von Behältnissen |
US5504332A (en) | 1994-08-26 | 1996-04-02 | Merck & Co., Inc. | Method and system for determining the homogeneity of tablets |
DE9416619U1 (de) | 1994-10-15 | 1995-01-12 | Bohle L B Pharmatech Gmbh | Vorrichtung zum Entgraten und Entstauben von Tabletten |
US5760399A (en) | 1995-10-02 | 1998-06-02 | Foss Nirsystems, Inc. | Measurement of transmission spectra of pharmaceutical tablets |
HUP9900730A3 (en) | 1995-11-23 | 2001-04-28 | Janssen Pharmaceutica Nv | Solid mixtures of cyclodextrins prepared via melt-extrusion |
JPH09271996A (ja) * | 1996-04-05 | 1997-10-21 | Sankyo Co Ltd | タブレット自動成形装置 |
DE19721467A1 (de) | 1997-05-22 | 1998-11-26 | Basf Ag | Verfahren zur Herstellung kleinteiliger Zubereitungen biologisch aktiver Stoffe |
JPH11276553A (ja) | 1998-03-26 | 1999-10-12 | Jgc Corp | 固形製剤の製造方法およびそのための製造装置 |
WO2001026632A1 (fr) | 1999-10-13 | 2001-04-19 | Kyowa Hakko Kogyo Co., Ltd. | Produit moule par compression et son procede de production |
CN100342846C (zh) | 1999-10-13 | 2007-10-17 | 协和发酵工业株式会社 | 压缩成形品及其制备方法 |
US20010034848A1 (en) | 2000-02-15 | 2001-10-25 | Gail Langley | Key card for personal home page access |
EP1157736A1 (de) | 2000-05-20 | 2001-11-28 | Glatt Maschinen- und Apparatebau AG | Anlage und Verfahren zur quasi-kontinuierlichen Behandlung eines teilchenförmigen Gutes |
US6499984B1 (en) | 2000-05-22 | 2002-12-31 | Warner-Lambert Company | Continuous production of pharmaceutical granulation |
ITRN20000051A1 (it) | 2000-12-22 | 2002-06-22 | Ascor Chimici Srl | Metodo e apparecchiatura per formare sferule composite contenenti principi attivi del tipo farmaceutico e/o integratori alimentari o cosmeti |
ITBO20010082A1 (it) | 2001-02-15 | 2002-08-16 | Ima Spa | Macchina comprimitrice per la produzione di compresse |
WO2003000169A1 (en) | 2001-06-20 | 2003-01-03 | Takeda Chemical Industries, Ltd. | Method of manufacturing tablet |
EP1423260B1 (en) | 2001-09-05 | 2007-01-24 | Courtoy N.V. | A rotary tablet press and a method of cleaning such a press |
ITBO20020094A1 (it) | 2002-02-22 | 2003-08-22 | Tecnea Engineering S R L | Procedimento per la realizzazione di composizioni ed apparecchiatura realizzante tale procedimento |
JP2003267480A (ja) | 2002-03-14 | 2003-09-25 | Niigata Eng Co Ltd | 粉粒体投入具および粉粒体の投入方法 |
AU2003230811A1 (en) | 2002-04-04 | 2003-10-27 | Euro-Celtique, S.A. | Method and apparatus for determining the homogeneity of a granulation during tableting |
DE10218220C1 (de) * | 2002-04-18 | 2003-06-26 | Korsch Ag | Verfahren zur umgebungsgeschützten Herstellung von Tabletten auf einer Tablettenpresse und Schutzeinrichtung an Tablettenpressen |
US7930053B2 (en) | 2003-12-23 | 2011-04-19 | Beacons Pharmaceuticals Pte Ltd | Virtual platform to facilitate automated production |
DE102004008321B3 (de) | 2004-02-20 | 2005-11-17 | Fette Gmbh | Verfahren und Vorrichtung zur Qualitätsüberwachung bei der Herstellung von Tabletten |
DE502004004292D1 (de) | 2004-05-27 | 2007-08-23 | Uhlmann Visiotec Gmbh | Tablettenpresse mit integrierter NIR-Messvorrichtung |
JP2008513205A (ja) | 2004-09-21 | 2008-05-01 | グラクソ グループ リミテッド | 混合システムおよび方法 |
DE102005061787A1 (de) | 2005-12-23 | 2007-06-28 | Fette Gmbh | Vorrichtung zur Erzeugung eines Unterdrucks im abgedichteten Raum einer Tablettenpresse und/oder eines Isolators |
DE102006002359B4 (de) | 2006-01-18 | 2009-01-02 | Fette Gmbh | Vorrichtung und Verfahren zur Überwachung der Produktion von Tabletten in einer Rundläuferpresse |
DE102006017196B4 (de) | 2006-04-12 | 2008-09-11 | Fette Gmbh | Verfahren zur Regelung der Wirkstoffmenge von Tabletten während der Produktion in einer Rundläufertablettenpresse |
RU2008147668A (ru) | 2006-05-04 | 2010-06-10 | Новартис АГ (CH) | Способ получения фармацевтических композиций посредством прессования нагреваемыми роликами |
US7771632B2 (en) | 2006-05-15 | 2010-08-10 | American Leistritz Extruder Corp. | Continuous melt spheronization apparatus and process for the production of pharmaceutical pellets |
CN101460297B (zh) | 2006-05-15 | 2012-10-10 | 库尔图瓦股份有限公司 | 用于控制压片机的方法及这种压片机 |
FI20070521L (fi) | 2006-11-10 | 2008-05-11 | Atacama Labs Oy | Rakeita, tabletteja ja rakeistusmenetelmä |
JP2010512286A (ja) | 2006-12-15 | 2010-04-22 | ゲーエーアー ファーマ システムズ アーゲー | 結合閉鎖具および2つの結合閉鎖具からなる連結装置 |
JP2008183168A (ja) * | 2007-01-30 | 2008-08-14 | Ebara Corp | 錠剤製造システム |
DE602008002570D1 (de) | 2007-02-27 | 2010-10-28 | Gea Pharma Systems Nv | Kontinuierlich arbeitende granulations- und trocknungsvorrichtung mit messeinheiten und verfahren zur kontinuierlichen granulation und trocknung |
WO2009022821A2 (en) | 2007-08-13 | 2009-02-19 | Hanall Pharmaceutical Company. Ltd | Combination preparation comprising inhibitor of hmg-coa reductase and aspirin and method for manufacturing the same |
WO2009130539A1 (en) | 2008-04-23 | 2009-10-29 | Gea Process Engineering (Nps) Ltd. | Apparatus for analysing solid, particulate material and method of analysing using the apparatus |
CA2723053A1 (en) | 2008-04-30 | 2009-11-05 | Novartis Ag | Continuous process for making pharmaceutical compositions |
US20100221374A1 (en) * | 2009-02-16 | 2010-09-02 | Le Floc H Jean Y | Modular tablet press and coater |
-
2009
- 2009-05-07 US US13/319,023 patent/US9713575B2/en active Active
- 2009-05-07 PT PT97863823T patent/PT2427166E/pt unknown
- 2009-05-07 DK DK09786382.3T patent/DK2427166T3/da active
- 2009-05-07 WO PCT/IB2009/051885 patent/WO2010128359A1/en active Application Filing
- 2009-05-07 EP EP09786382.3A patent/EP2427166B1/en not_active Revoked
- 2009-05-07 CN CN2009801590959A patent/CN102438578A/zh active Pending
- 2009-05-07 ES ES09786382.3T patent/ES2441446T3/es active Active
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- 2009-05-07 JP JP2012509101A patent/JP2012525895A/ja active Pending
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2013
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2016
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DK2427166T3 (da) | 2014-01-27 |
HRP20131155T1 (hr) | 2014-02-28 |
US20120061869A1 (en) | 2012-03-15 |
CN102438578A (zh) | 2012-05-02 |
JP2012525895A (ja) | 2012-10-25 |
US9713575B2 (en) | 2017-07-25 |
BRPI0925048B1 (pt) | 2019-07-09 |
US10016340B2 (en) | 2018-07-10 |
EP2427166A1 (en) | 2012-03-14 |
US20160310365A1 (en) | 2016-10-27 |
EP2427166B1 (en) | 2013-10-16 |
BRPI0925048A2 (pt) | 2015-08-04 |
ES2441446T3 (es) | 2014-02-04 |
PT2427166E (pt) | 2014-01-20 |
WO2010128359A1 (en) | 2010-11-11 |
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