PL3833964T3 - Zastosowanie spektroskopii ramana do produkcji proszków do inhalacji - Google Patents
Zastosowanie spektroskopii ramana do produkcji proszków do inhalacjiInfo
- Publication number
- PL3833964T3 PL3833964T3 PL19779127.0T PL19779127T PL3833964T3 PL 3833964 T3 PL3833964 T3 PL 3833964T3 PL 19779127 T PL19779127 T PL 19779127T PL 3833964 T3 PL3833964 T3 PL 3833964T3
- Authority
- PL
- Poland
- Prior art keywords
- manufacture
- application
- raman spectroscopy
- inhalation powders
- inhalation
- Prior art date
Links
- 238000001069 Raman spectroscopy Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000843 powder Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/213—Measuring of the properties of the mixtures, e.g. temperature, density or colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/85—Investigating moving fluids or granular solids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/85—Investigating moving fluids or granular solids
- G01N2021/8592—Grain or other flowing solid samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/88—Investigating the presence of flaws or contamination
- G01N21/95—Investigating the presence of flaws or contamination characterised by the material or shape of the object to be examined
- G01N21/9508—Capsules; Tablets
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862715463P | 2018-08-07 | 2018-08-07 | |
PCT/IB2019/056737 WO2020031119A1 (en) | 2018-08-07 | 2019-08-07 | Application of raman spectroscopy for the manufacture of inhalation powders |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3833964T3 true PL3833964T3 (pl) | 2023-09-04 |
Family
ID=68072878
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL19779127.0T PL3833964T3 (pl) | 2018-08-07 | 2019-08-07 | Zastosowanie spektroskopii ramana do produkcji proszków do inhalacji |
Country Status (6)
Country | Link |
---|---|
US (3) | US11774363B2 (pl) |
EP (2) | EP3910324A1 (pl) |
ES (1) | ES2953293T3 (pl) |
PL (1) | PL3833964T3 (pl) |
PT (1) | PT3833964T (pl) |
WO (1) | WO2020031119A1 (pl) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT3833964T (pt) * | 2018-08-07 | 2023-08-17 | Norton Waterford Ltd | Aplicação de espetroscopia de raman para o fabrico de pós de inalação |
CN116615201A (zh) | 2020-08-14 | 2023-08-18 | 诺顿(沃特福特)有限公司 | 丙酸氟替卡松和硫酸沙丁胺醇的可吸入制剂 |
GB202012742D0 (en) * | 2020-08-14 | 2020-09-30 | Norton Waterford Ltd | An inhalable medicament |
WO2024010538A1 (en) * | 2022-07-07 | 2024-01-11 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | A process for the preparation of dry powder compositions for inhalation using different mixers |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1242211A (en) | 1967-08-08 | 1971-08-11 | Fisons Pharmaceuticals Ltd | Pharmaceutical composition |
GB1381872A (en) | 1971-06-22 | 1975-01-29 | Fisons Ltd | Pharmaceutical compositions for inhalation |
US7448375B2 (en) | 1993-01-29 | 2008-11-11 | Aradigm Corporation | Method of treating diabetes mellitus in a patient |
GB9322014D0 (en) | 1993-10-26 | 1993-12-15 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
US7871598B1 (en) * | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
JP4044330B2 (ja) | 2001-12-25 | 2008-02-06 | ミネベア株式会社 | Rbc又はcrbcの微粉末が分散した合成樹脂発泡成型体、その製造方法及びその用途 |
US20050032235A1 (en) | 2003-06-18 | 2005-02-10 | Srinivas Tummala | Method of monitoring the blending of a mixture |
WO2005044186A2 (en) * | 2003-10-28 | 2005-05-19 | Glaxo Group Limited | Inhalable pharmaceutical formulations employing desiccating agents and methods of administering the same |
US20080025966A1 (en) * | 2004-01-30 | 2008-01-31 | Currie Mark G | Methods And Compositions For The Treatment Of Gastrointestinal disorders |
AU2005216061B2 (en) | 2004-02-24 | 2010-05-27 | Microdose Therapeutx, Inc. | Synthetic jet based medicament delivery method and apparatus |
US20050287212A1 (en) * | 2004-06-28 | 2005-12-29 | Liang-Chang Dong | Oral delivery system comprising a drug/polymer complex |
WO2008021142A2 (en) * | 2006-08-09 | 2008-02-21 | Glaxo Group Limited | Process for manufacturing lactose |
BRPI0910875B8 (pt) | 2008-03-27 | 2021-06-22 | Mannkind Corp | sistema de inalação de pó seco |
EP2296628B1 (en) * | 2008-05-22 | 2014-05-14 | 3M Innovative Properties Company | Process for manufacturing flowable powder drug compositions |
EP2321023B1 (en) * | 2008-07-18 | 2016-06-15 | Prosonix Limited | Process for improving crystallinity of fluticasone particles |
EP2221048A1 (en) | 2009-02-18 | 2010-08-25 | Siegfried Generics International AG | Pharmaceutical composition for inhalation |
EP2427166B1 (en) * | 2009-05-07 | 2013-10-16 | Gea Pharma Systems Limited | Tablet production module and method for continuous production of tablets |
GB0918431D0 (en) * | 2009-10-21 | 2009-12-09 | Prosonix Ltd | Process for improving crystallinity |
JP5878475B2 (ja) * | 2009-12-14 | 2016-03-08 | シエシー ファルマセウティチィ ソシエタ ペル アチオニ | 吸入用抗生物質微粒子 |
BR112012024059B1 (pt) * | 2010-04-01 | 2021-06-01 | Chiesi Farmaceutici S.P.A. | Processo de preparo de um excipiente para composições farmacêuticas em pó para inalação, partículas carreadoras para uma formulação farmacêutica de pó seco, composição farmacêutica em forma de pó seco para inalação e inalador de pó seco |
KR101863523B1 (ko) * | 2010-04-21 | 2018-05-31 | 키에시 파르마슈티시 엣스. 피. 에이. | 정전하가 감소된 입자를 제공하는 방법 |
MA34326B1 (fr) * | 2010-06-22 | 2013-06-01 | Chiesi Farma Spa | Formulation de poudre sèche comprenant un médicament antimuscarinique |
CN105640925B (zh) * | 2010-08-30 | 2019-08-16 | 普马特里克斯营业公司 | 干燥粉末配方及用于治疗肺部疾病的方法 |
RU2640921C2 (ru) * | 2010-09-29 | 2018-01-12 | Пулмэтрикс, Инк. | Катионы одновалентных металлов сухих порошков для ингаляций |
EP2621568B1 (en) | 2010-09-30 | 2018-11-07 | Novartis AG | Inhaler |
WO2013052844A1 (en) * | 2011-10-07 | 2013-04-11 | Pulmatrix, Inc. | Methods for treating and diagnosing respiratory tract infections |
EP2768480A1 (en) * | 2011-10-21 | 2014-08-27 | Rigel Pharmaceuticals, Inc. | Method and device for administering xinafoate salt of n4-(2,2-difluoro-4h-benzo [1,4]oxazin-3-one) -6-yl]-5-fluoro-n2- [3- (methylaminocarbonylmethyleneoxy) phenyl]2,4-pyrimidinediamine |
MY165888A (en) * | 2012-01-25 | 2018-05-18 | Chiesi Farm Spa | Dry powder formulation comprising a corticosteroid and a beta-adrenergic for administration by inhalation |
JP6231022B2 (ja) * | 2012-02-28 | 2017-11-15 | アイシューティカ ホールディングス インク.Iceutica Holdings Inc. | 吸入可能な医薬組成物 |
CN104487075A (zh) * | 2012-02-29 | 2015-04-01 | 普马特里克斯公司 | 可吸入干粉剂 |
BR112015010601B1 (pt) | 2012-11-09 | 2022-07-19 | Civitas Therapeutics, Inc. | Composição farmacêutica e uso da composição |
EP2738172A1 (en) | 2012-11-28 | 2014-06-04 | Almirall, S.A. | New bicyclic compounds as crac channel modulators |
GB201319265D0 (en) * | 2013-10-31 | 2013-12-18 | Norton Waterford Ltd | Medicament inhaler |
US9980904B2 (en) * | 2014-10-16 | 2018-05-29 | Teva Branded Pharmaceutical Products R&D, Inc. | Dry powder formulation |
GB201614939D0 (en) * | 2016-09-02 | 2016-10-19 | Glaxosmithkline Ip Dev Ltd | Crystalline hydrate |
PT3833964T (pt) * | 2018-08-07 | 2023-08-17 | Norton Waterford Ltd | Aplicação de espetroscopia de raman para o fabrico de pós de inalação |
CN116615201A (zh) | 2020-08-14 | 2023-08-18 | 诺顿(沃特福特)有限公司 | 丙酸氟替卡松和硫酸沙丁胺醇的可吸入制剂 |
-
2019
- 2019-08-07 PT PT197791270T patent/PT3833964T/pt unknown
- 2019-08-07 WO PCT/IB2019/056737 patent/WO2020031119A1/en unknown
- 2019-08-07 EP EP21181874.5A patent/EP3910324A1/en active Pending
- 2019-08-07 ES ES19779127T patent/ES2953293T3/es active Active
- 2019-08-07 EP EP19779127.0A patent/EP3833964B1/en active Active
- 2019-08-07 US US17/266,884 patent/US11774363B2/en active Active
- 2019-08-07 PL PL19779127.0T patent/PL3833964T3/pl unknown
-
2021
- 2021-07-20 US US17/380,535 patent/US11366064B2/en active Active
-
2022
- 2022-05-16 US US17/745,686 patent/US20220276173A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3910324A1 (en) | 2021-11-17 |
PT3833964T (pt) | 2023-08-17 |
WO2020031119A1 (en) | 2020-02-13 |
US20210372931A1 (en) | 2021-12-02 |
US20220276173A1 (en) | 2022-09-01 |
US11366064B2 (en) | 2022-06-21 |
US20210293715A1 (en) | 2021-09-23 |
ES2953293T3 (es) | 2023-11-10 |
EP3833964B1 (en) | 2023-07-26 |
US11774363B2 (en) | 2023-10-03 |
EP3833964A1 (en) | 2021-06-16 |
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