BRPI0810064B8 - compostos contendo nitrogênio tricíclico como agentes antibacterianos, composições farmacêuticas que compreendem os ditos compostos e uso dos mesmos para o tratamento de infecções bacterianas em mamíferos - Google Patents
compostos contendo nitrogênio tricíclico como agentes antibacterianos, composições farmacêuticas que compreendem os ditos compostos e uso dos mesmos para o tratamento de infecções bacterianas em mamíferosInfo
- Publication number
- BRPI0810064B8 BRPI0810064B8 BRPI0810064A BRPI0810064A BRPI0810064B8 BR PI0810064 B8 BRPI0810064 B8 BR PI0810064B8 BR PI0810064 A BRPI0810064 A BR PI0810064A BR PI0810064 A BRPI0810064 A BR PI0810064A BR PI0810064 B8 BRPI0810064 B8 BR PI0810064B8
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- mammals
- antibacterial agents
- treatment
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/16—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0707705A GB0707705D0 (en) | 2007-04-20 | 2007-04-20 | Compounds |
| GB0707705.0 | 2007-04-20 | ||
| GB0720569A GB0720569D0 (en) | 2007-10-19 | 2007-10-19 | Compounds |
| GB0720569.3 | 2007-10-19 | ||
| GB0805311A GB0805311D0 (en) | 2008-03-20 | 2008-03-20 | Compounds |
| GB0805311.8 | 2008-03-20 | ||
| PCT/EP2008/054621 WO2008128942A1 (en) | 2007-04-20 | 2008-04-16 | Tricyclic nitrogen containing compounds as antibacterial agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0810064A2 BRPI0810064A2 (pt) | 2019-08-27 |
| BRPI0810064B1 BRPI0810064B1 (pt) | 2021-03-30 |
| BRPI0810064B8 true BRPI0810064B8 (pt) | 2021-05-25 |
Family
ID=39580226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0810064A BRPI0810064B8 (pt) | 2007-04-20 | 2008-04-16 | compostos contendo nitrogênio tricíclico como agentes antibacterianos, composições farmacêuticas que compreendem os ditos compostos e uso dos mesmos para o tratamento de infecções bacterianas em mamíferos |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US8389524B2 (enExample) |
| EP (1) | EP2137196B1 (enExample) |
| JP (1) | JP5389013B2 (enExample) |
| KR (1) | KR101567096B1 (enExample) |
| CN (1) | CN101687887B (enExample) |
| AR (1) | AR066111A1 (enExample) |
| AT (1) | ATE483717T1 (enExample) |
| AU (1) | AU2008240764C1 (enExample) |
| BR (1) | BRPI0810064B8 (enExample) |
| CA (1) | CA2684659C (enExample) |
| CL (1) | CL2008001122A1 (enExample) |
| CO (1) | CO6251368A2 (enExample) |
| CR (2) | CR11123A (enExample) |
| CY (1) | CY1111248T1 (enExample) |
| DE (1) | DE602008002912D1 (enExample) |
| DK (1) | DK2137196T3 (enExample) |
| DO (1) | DOP2009000240A (enExample) |
| EA (1) | EA015821B1 (enExample) |
| HR (1) | HRP20100574T1 (enExample) |
| IL (1) | IL201204A0 (enExample) |
| MA (1) | MA31324B1 (enExample) |
| MX (1) | MX2009011317A (enExample) |
| MY (1) | MY149347A (enExample) |
| NZ (1) | NZ579877A (enExample) |
| PE (1) | PE20090274A1 (enExample) |
| PL (1) | PL2137196T3 (enExample) |
| PT (1) | PT2137196E (enExample) |
| SI (1) | SI2137196T1 (enExample) |
| TW (1) | TWI431006B (enExample) |
| UY (1) | UY31038A1 (enExample) |
| WO (1) | WO2008128942A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1954697B1 (en) * | 2005-10-21 | 2010-02-24 | Glaxo Group Limited | Peri condensed tricyclic compounds useful as antibacterial agents |
| EP1847543A1 (de) | 2006-04-19 | 2007-10-24 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen |
| GB0608263D0 (en) | 2006-04-26 | 2006-06-07 | Glaxo Group Ltd | Compounds |
| EP2205609B1 (de) | 2007-10-19 | 2017-03-29 | Boehringer Ingelheim International GmbH | Heterocyclus-substituierte piperazino-dihydrothienopyrimidine |
| EP2215093B1 (de) | 2007-10-19 | 2011-12-14 | Boehringer Ingelheim International GmbH | Neue piperazino-dihydrothienopyrimidin-derivate |
| JP5150728B2 (ja) | 2007-10-19 | 2013-02-27 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換ピペリジノ−ジヒドロチエノピリミジン |
| MX2010008922A (es) | 2008-02-20 | 2010-09-07 | Actelion Pharmaceuticals Ltd | Compuestos antibioticos azatriciclicos. |
| MX2010012732A (es) * | 2008-05-23 | 2010-12-07 | Glaxo Group Ltd | Compuestos que contienen nitrogeno triciclico y su uso como antibacterianos. |
| WO2009141399A1 (en) * | 2008-05-23 | 2009-11-26 | Glaxo Group Limited | Tricyclic nitrogen containing compounds and their use as antibacterials |
| MY158520A (en) | 2008-10-07 | 2016-10-14 | Actelion Pharmaceuticals Ltd | Tricyclic oxazolidinone antibiotic compounds |
| WO2010043714A1 (en) | 2008-10-17 | 2010-04-22 | Glaxo Group Limited | Tricyclic nitrogen compounds used as antibacterials |
| CA2749163A1 (en) | 2009-01-14 | 2010-07-22 | The Salk Institute For Biological Studies | Methods for screening and compounds that protect against amyloid diseases |
| AR076222A1 (es) | 2009-04-09 | 2011-05-26 | Actelion Pharmaceuticals Ltd | Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen |
| TW201130854A (en) | 2009-12-22 | 2011-09-16 | Bayer Schering Pharma Ag | Pyridinone derivatives and pharmaceutical compositions thereof |
| NZ603268A (en) * | 2010-05-04 | 2015-02-27 | Alkermes Pharma Ireland Ltd | Process for synthesizing oxidized lactam compounds |
| US9802954B2 (en) | 2011-08-24 | 2017-10-31 | Boehringer Ingelheim International Gmbh | Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma |
| US20130059866A1 (en) | 2011-08-24 | 2013-03-07 | Boehringer Ingelheim International Gmbh | Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma |
| CN103113291B (zh) * | 2013-02-04 | 2015-03-04 | 浙江大学 | 一种3位烯基吡啶衍生物的合成方法 |
| US9975910B2 (en) | 2013-07-23 | 2018-05-22 | Eisai R&D Management Co., Ltd. | Hetero-fused cyclic compound |
| WO2016027249A1 (en) * | 2014-08-22 | 2016-02-25 | Glaxosmithkline Intellectual Property Development Limited | Tricyclic nitrogen containing compounds for treating neisseria gonorrhoea infection |
| KR102474326B1 (ko) * | 2016-06-22 | 2022-12-05 | 반더빌트유니버시티 | 무스카린성 아세틸콜린 수용체 m4의 양성 알로스테릭 조절제 |
| WO2018195098A1 (en) | 2017-04-17 | 2018-10-25 | Ohio State Innovation Foundation | Type ii topoisomerase inhibitors and methods of making and using thereof |
| EP3946342A1 (en) | 2019-04-03 | 2022-02-09 | GlaxoSmithKline Intellectual Property Development Limited | Gepotidacin for use in the treatment of bacterial urinary tract infections |
| US20220257615A1 (en) * | 2019-07-05 | 2022-08-18 | Glaxosmithkline Intellectual Property Development Limied | Combination for the treatment of infections caused by mycoplasma genitalium |
| JP2023528560A (ja) | 2020-04-02 | 2023-07-05 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | ゲポチダシンを用いて淋菌感染症を治療するためのレジメン |
| WO2021219637A1 (en) | 2020-04-29 | 2021-11-04 | Glaxosmithkline Intellectual Property Development Limited | Crystalline forms of gepotidacin |
| CN111494241B (zh) * | 2020-06-01 | 2023-03-24 | 湖北洁世达环保科技有限公司 | 一种纸巾柔润保湿液 |
| EP4288035A1 (en) * | 2021-02-05 | 2023-12-13 | GlaxoSmithKline Intellectual Property Development Limited | Oral solid dose formulations |
| EP4465989A1 (en) | 2022-01-21 | 2024-11-27 | GlaxoSmithKline Intellectual Property Development Limited | Gepotidacin and vancomycin for use in the treatment of an infection caused by staphylococcus saprophyticus |
| EP4316463A1 (en) | 2022-08-02 | 2024-02-07 | GlaxoSmithKline Intellectual Property Development Limited | Novel formulation |
| JP2025532252A (ja) | 2022-09-26 | 2025-09-29 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | 処置方法 |
Family Cites Families (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6403610B1 (en) * | 1999-09-17 | 2002-06-11 | Aventis Pharma S.A. | Quinolylpropylpiperidine derivatives, their preparation and the compositions which comprise them |
| US6525049B2 (en) * | 2000-07-05 | 2003-02-25 | Pharmacia & Upjohn Company | Pyrroloquinolones as antiviral agents |
| US6624159B2 (en) * | 2000-07-12 | 2003-09-23 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
| DE60125373T2 (de) * | 2000-07-26 | 2007-10-18 | Smithkline Beecham P.L.C., Brentford | Aminopiperidin chinoline und ihre azaisosteren analoga mit antibakterieller wirkung |
| US6603005B2 (en) * | 2000-11-15 | 2003-08-05 | Aventis Pharma S.A. | Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them |
| GB0031088D0 (en) * | 2000-12-20 | 2001-01-31 | Smithkline Beecham Plc | Medicaments |
| EP1345903A1 (en) * | 2000-12-21 | 2003-09-24 | Ciba SC Holding AG | Crystalline forms of cerivastatin sodium |
| GB0101577D0 (en) * | 2001-01-22 | 2001-03-07 | Smithkline Beecham Plc | Compounds |
| US6602884B2 (en) | 2001-03-13 | 2003-08-05 | Aventis Pharma S.A. | Quinolylpropylpiperidine derivatives, their preparation, and compositions containing them |
| GB0112836D0 (en) * | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
| GB0112834D0 (en) * | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
| GB0118238D0 (en) * | 2001-07-26 | 2001-09-19 | Smithkline Beecham Plc | Medicaments |
| AU2002350217A1 (en) * | 2001-12-04 | 2003-06-17 | Bristol-Myers Squibb Company | Glycinamides as factor xa inhibitors |
| WO2003064431A2 (en) * | 2002-01-29 | 2003-08-07 | Glaxo Group Limited | Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them |
| WO2003064421A1 (en) | 2002-01-29 | 2003-08-07 | Glaxo Group Limited | Aminopiperidine derivatives |
| AR040335A1 (es) * | 2002-06-26 | 2005-03-30 | Glaxo Group Ltd | Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto |
| TW200409637A (en) * | 2002-06-26 | 2004-06-16 | Glaxo Group Ltd | Compounds |
| GB0217294D0 (en) * | 2002-07-25 | 2002-09-04 | Glaxo Group Ltd | Medicaments |
| FR2844270B1 (fr) * | 2002-09-11 | 2006-05-19 | Aventis Pharma Sa | Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent |
| FR2844268B1 (fr) * | 2002-09-11 | 2004-10-22 | Aventis Pharma Sa | Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent |
| AU2003301414B8 (en) * | 2002-10-10 | 2010-06-17 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Novel compounds with antibacterial activity |
| DE60331849D1 (de) * | 2002-11-05 | 2010-05-06 | Glaxosmithkline Llc | Antibakterielle wirkstoffe |
| AU2003291227A1 (en) * | 2002-11-05 | 2004-06-07 | Smithkline Beecham Corporation | Antibacterial agents |
| TW200427688A (en) * | 2002-12-18 | 2004-12-16 | Glaxo Group Ltd | Antibacterial agents |
| TW200507841A (en) * | 2003-03-27 | 2005-03-01 | Glaxo Group Ltd | Antibacterial agents |
| US7232833B2 (en) * | 2003-03-28 | 2007-06-19 | Novexel | 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them |
| DE10316081A1 (de) * | 2003-04-08 | 2004-10-21 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
| US7348434B2 (en) * | 2003-08-08 | 2008-03-25 | Antony Bigot | 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them |
| FR2867472B1 (fr) | 2004-03-12 | 2008-07-18 | Aventis Pharma Sa | Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent |
| US7691850B2 (en) * | 2004-06-15 | 2010-04-06 | Glaxo Group Limited | Antibacterial agents |
| FR2872164B1 (fr) * | 2004-06-29 | 2006-11-17 | Aventis Pharma Sa | Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent |
| EP1773831A1 (en) | 2004-07-08 | 2007-04-18 | Glaxo Group Limited | Antibacterial agents |
| WO2006010040A2 (en) * | 2004-07-09 | 2006-01-26 | Glaxo Group Limited | Antibacterial agents |
| EP1773343A4 (en) * | 2004-07-13 | 2009-05-13 | Glaxo Group Ltd | ANTIBACTERIAL AGENTS |
| US20070270417A1 (en) | 2004-07-22 | 2007-11-22 | Glaxo Group Limited | Antibacterial Agents |
| DE602005024151D1 (de) * | 2004-08-02 | 2010-11-25 | Glaxo Group Ltd | Antibakterielle mittel |
| US20070161627A1 (en) * | 2004-08-09 | 2007-07-12 | Miller William H | Antibacterial agents |
| DE102004041163A1 (de) * | 2004-08-25 | 2006-03-02 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
| JP4887297B2 (ja) | 2004-09-24 | 2012-02-29 | アクテリオン ファーマシューティカルズ リミテッド | 新規二環式抗生物質 |
| ATE466857T1 (de) * | 2004-10-05 | 2010-05-15 | Actelion Pharmaceuticals Ltd | Neue piperidin-antibiotika |
| WO2006046552A1 (ja) | 2004-10-27 | 2006-05-04 | Toyama Chemical Co., Ltd. | 新規な含窒素複素環化合物およびその塩 |
| WO2006081178A2 (en) * | 2005-01-25 | 2006-08-03 | Glaxo Group Limited | Antibacterial agents |
| WO2006081179A1 (en) * | 2005-01-25 | 2006-08-03 | Glaxo Group Limited | Antibacterial agents |
| US7605169B2 (en) * | 2005-01-25 | 2009-10-20 | Glaxo Group Limited | Antibacterial agents |
| WO2006081289A2 (en) * | 2005-01-25 | 2006-08-03 | Glaxo Group Limited | Antibacterial agents |
| WO2006081182A2 (en) * | 2005-01-25 | 2006-08-03 | Glaxo Group Limited | Antibacterial agents |
| WO2006099884A1 (en) | 2005-03-24 | 2006-09-28 | Actelion Percurex Ag | Beta-aminoalcohol antibiotics |
| EP1863483A4 (en) | 2005-03-31 | 2010-03-31 | Janssen Pharmaceutica Nv | Bicyclic pyrazole compounds as anti-bacteriostatic agents |
| AU2006250987A1 (en) * | 2005-05-24 | 2006-11-30 | Astrazeneca Ab | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity |
| EP1888574B1 (en) * | 2005-05-25 | 2009-09-02 | Actelion Pharmaceuticals Ltd. | New antibiotic derivatives |
| MY150958A (en) * | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| EP1900732A4 (en) | 2005-06-24 | 2009-11-18 | Toyama Chemical Co Ltd | NEW NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF |
| EP1954697B1 (en) * | 2005-10-21 | 2010-02-24 | Glaxo Group Limited | Peri condensed tricyclic compounds useful as antibacterial agents |
| US20070185153A1 (en) * | 2005-12-22 | 2007-08-09 | Nathalie Cailleau | Compounds |
| EP2001887B1 (en) * | 2006-04-06 | 2010-09-15 | Glaxo Group Limited | Pyrrolo-quinoxalinone derivatives as antibacterials |
| EP2007377A4 (en) * | 2006-04-06 | 2011-08-17 | Glaxo Group Ltd | ANTIBACTERIAL ACTIVE SUBSTANCES |
| GB0608263D0 (en) * | 2006-04-26 | 2006-06-07 | Glaxo Group Ltd | Compounds |
| US20100256124A1 (en) * | 2006-06-09 | 2010-10-07 | David Thomas Davies | Substituted 1-Methyl-1H-Quinolin-2-Ones And 1-Methyl-1H-1,5-Naphthyridin-2-Ones As Antibacterials |
| GB0613208D0 (en) * | 2006-07-03 | 2006-08-09 | Glaxo Group Ltd | Compounds |
| EP1992628A1 (en) * | 2007-05-18 | 2008-11-19 | Glaxo Group Limited | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones |
| GB0705672D0 (en) * | 2007-03-23 | 2007-05-02 | Glaxo Group Ltd | Compounds |
| EP1980251A1 (en) * | 2007-04-13 | 2008-10-15 | Glaxo Group Limited | Pyrrolo[3,2,1-ij]quinoline-4-one derivatives for treating tuberculosis |
| GB0707708D0 (en) * | 2007-04-20 | 2007-05-30 | Glaxo Group Ltd | Compounds |
| GB0707706D0 (en) * | 2007-04-20 | 2007-05-30 | Glaxo Group Ltd | Compounds |
| EP2005995A1 (en) * | 2007-06-22 | 2008-12-24 | Glaxo Group Limited | Heterocyclic compounds for the treatment of tuberculosis |
| GB0800367D0 (en) * | 2008-01-09 | 2008-02-20 | Glaxo Group Ltd | Compounds |
-
2008
- 2008-04-16 CA CA2684659A patent/CA2684659C/en active Active
- 2008-04-16 AT AT08749580T patent/ATE483717T1/de active
- 2008-04-16 MX MX2009011317A patent/MX2009011317A/es active IP Right Grant
- 2008-04-16 PL PL08749580T patent/PL2137196T3/pl unknown
- 2008-04-16 WO PCT/EP2008/054621 patent/WO2008128942A1/en not_active Ceased
- 2008-04-16 BR BRPI0810064A patent/BRPI0810064B8/pt active IP Right Grant
- 2008-04-16 HR HR20100574T patent/HRP20100574T1/hr unknown
- 2008-04-16 JP JP2010503491A patent/JP5389013B2/ja active Active
- 2008-04-16 NZ NZ579877A patent/NZ579877A/en unknown
- 2008-04-16 CN CN2008800213034A patent/CN101687887B/zh active Active
- 2008-04-16 AU AU2008240764A patent/AU2008240764C1/en active Active
- 2008-04-16 DE DE602008002912T patent/DE602008002912D1/de active Active
- 2008-04-16 US US12/596,685 patent/US8389524B2/en active Active
- 2008-04-16 DK DK08749580.0T patent/DK2137196T3/da active
- 2008-04-16 KR KR1020097024090A patent/KR101567096B1/ko active Active
- 2008-04-16 EP EP08749580A patent/EP2137196B1/en active Active
- 2008-04-16 SI SI200830103T patent/SI2137196T1/sl unknown
- 2008-04-16 MY MYPI20094376A patent/MY149347A/en unknown
- 2008-04-16 EA EA200970987A patent/EA015821B1/ru not_active IP Right Cessation
- 2008-04-16 PT PT08749580T patent/PT2137196E/pt unknown
- 2008-04-18 AR ARP080101605A patent/AR066111A1/es active IP Right Grant
- 2008-04-18 TW TW097114042A patent/TWI431006B/zh active
- 2008-04-18 PE PE2008000682A patent/PE20090274A1/es active IP Right Grant
- 2008-04-18 UY UY31038A patent/UY31038A1/es active IP Right Grant
- 2008-04-18 CL CL200801122A patent/CL2008001122A1/es unknown
-
2009
- 2009-09-24 IL IL201204A patent/IL201204A0/en active IP Right Grant
- 2009-10-09 DO DO2009000240A patent/DOP2009000240A/es unknown
- 2009-10-19 CO CO09116570A patent/CO6251368A2/es not_active Application Discontinuation
- 2009-10-21 MA MA32296A patent/MA31324B1/fr unknown
- 2009-11-20 CR CR11123A patent/CR11123A/es unknown
-
2010
- 2010-11-24 CY CY20101101052T patent/CY1111248T1/el unknown
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2015
- 2015-10-23 CR CR20150586A patent/CR20150586A/es unknown
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