CO6382113A2 - Compuestos quimicos - Google Patents

Compuestos quimicos

Info

Publication number
CO6382113A2
CO6382113A2 CO11058050A CO11058050A CO6382113A2 CO 6382113 A2 CO6382113 A2 CO 6382113A2 CO 11058050 A CO11058050 A CO 11058050A CO 11058050 A CO11058050 A CO 11058050A CO 6382113 A2 CO6382113 A2 CO 6382113A2
Authority
CO
Colombia
Prior art keywords
chemical compounds
compounds
infections
possess
act
Prior art date
Application number
CO11058050A
Other languages
English (en)
Inventor
Mark Cronin
Bolin Geng
Folkert Reck
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CO6382113A2 publication Critical patent/CO6382113A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a compuestos aminociclohexilo de fórmula (I):y sales farmacéuticamente aceptables de los mismos, a su uso en el tratamiento de infecciones y a sus métodos de preparación; compuestos que poseen la capacidad de actuar como agentes antimicrobianos.
CO11058050A 2008-11-14 2011-05-11 Compuestos quimicos CO6382113A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11470608P 2008-11-14 2008-11-14
US16384809P 2009-03-26 2009-03-26

Publications (1)

Publication Number Publication Date
CO6382113A2 true CO6382113A2 (es) 2012-02-15

Family

ID=41463108

Family Applications (1)

Application Number Title Priority Date Filing Date
CO11058050A CO6382113A2 (es) 2008-11-14 2011-05-11 Compuestos quimicos

Country Status (20)

Country Link
US (1) US20110288084A1 (es)
EP (1) EP2370444A1 (es)
JP (1) JP2012508789A (es)
KR (1) KR20110093797A (es)
CN (1) CN102216308A (es)
AR (1) AR074340A1 (es)
AU (1) AU2009315425A1 (es)
BR (1) BRPI0921148A2 (es)
CA (1) CA2742520A1 (es)
CO (1) CO6382113A2 (es)
CR (1) CR20110256A (es)
CU (1) CU20110108A7 (es)
EA (1) EA201100754A1 (es)
EC (1) ECSP11011053A (es)
IL (1) IL211941A0 (es)
MX (1) MX2011005106A (es)
TW (1) TW201022279A (es)
UY (1) UY32247A (es)
WO (1) WO2010055348A1 (es)
ZA (1) ZA201104395B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013003383A1 (en) * 2011-06-27 2013-01-03 Kyorin Pharmaceutical Co., Ltd. Bridged bicyclic compounds for the treatment of bacterial infections
AR096135A1 (es) * 2013-05-02 2015-12-09 Actelion Pharmaceuticals Ltd Derivados de la quinolona
TW201722965A (zh) 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 用於抗菌應用之化合物
WO2017040963A1 (en) 2015-09-03 2017-03-09 Forma Therapeutics, Inc. [6,6] fused bicyclic hdac8 inhibitors
US10633366B2 (en) * 2016-06-08 2020-04-28 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Antibacterial compounds
FI3634968T3 (fi) 2017-06-08 2023-04-26 Bugworks Res Inc Bakteerilääkkeinä käyttökelpoisia heterosyklisiä yhdisteitä ja menetelmä niiden valmistamiseksi

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
KR101409261B1 (ko) * 2006-05-26 2014-06-18 다이쇼 세이야꾸 가부시끼가이샤 신규의 복소환 화합물 또는 그 염 및 그 중간체
CL2007003693A1 (es) * 2006-12-22 2008-06-27 Actelion Pharmaceuticals Ltd Compuestos derivados de pirido [3,2-b] [1,4] tiazina; composicion farmaceutica que contiene dichos compuestos; y su uso en el tratamiento de infecciones bacterianas.

Also Published As

Publication number Publication date
BRPI0921148A2 (pt) 2016-02-23
KR20110093797A (ko) 2011-08-18
TW201022279A (en) 2010-06-16
IL211941A0 (en) 2011-06-30
WO2010055348A1 (en) 2010-05-20
JP2012508789A (ja) 2012-04-12
AU2009315425A1 (en) 2010-05-20
EA201100754A1 (ru) 2012-01-30
ZA201104395B (en) 2012-03-28
CR20110256A (es) 2011-07-04
CN102216308A (zh) 2011-10-12
UY32247A (es) 2010-06-30
CA2742520A1 (en) 2010-05-20
AR074340A1 (es) 2011-01-12
ECSP11011053A (es) 2011-06-30
CU20110108A7 (es) 2012-01-31
US20110288084A1 (en) 2011-11-24
MX2011005106A (es) 2011-05-30
EP2370444A1 (en) 2011-10-05

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