CR20110256A - [4-(1-amino-etil)-ciclohexil]-metil-aminas como antibacterianos - Google Patents

[4-(1-amino-etil)-ciclohexil]-metil-aminas como antibacterianos

Info

Publication number
CR20110256A
CR20110256A CR20110256A CR20110256A CR20110256A CR 20110256 A CR20110256 A CR 20110256A CR 20110256 A CR20110256 A CR 20110256A CR 20110256 A CR20110256 A CR 20110256A CR 20110256 A CR20110256 A CR 20110256A
Authority
CR
Costa Rica
Prior art keywords
ciclohexil
aminas
etil
metil
antibacterials
Prior art date
Application number
CR20110256A
Other languages
English (en)
Inventor
Mark Cronin
Bolin Geng
Folkert Reck
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CR20110256A publication Critical patent/CR20110256A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invención se refiere a compuestos de la fórmula (I) y sales farmacéuticamente aceptables de los mismos, asu uso en el tratamiento de infecciones bacterianas y sus métodos de preparación.
CR20110256A 2008-11-14 2011-05-13 [4-(1-amino-etil)-ciclohexil]-metil-aminas como antibacterianos CR20110256A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11470608P 2008-11-14 2008-11-14
US16384809P 2009-03-26 2009-03-26

Publications (1)

Publication Number Publication Date
CR20110256A true CR20110256A (es) 2011-07-04

Family

ID=41463108

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20110256A CR20110256A (es) 2008-11-14 2011-05-13 [4-(1-amino-etil)-ciclohexil]-metil-aminas como antibacterianos

Country Status (20)

Country Link
US (1) US20110288084A1 (es)
EP (1) EP2370444A1 (es)
JP (1) JP2012508789A (es)
KR (1) KR20110093797A (es)
CN (1) CN102216308A (es)
AR (1) AR074340A1 (es)
AU (1) AU2009315425A1 (es)
BR (1) BRPI0921148A2 (es)
CA (1) CA2742520A1 (es)
CO (1) CO6382113A2 (es)
CR (1) CR20110256A (es)
CU (1) CU20110108A7 (es)
EA (1) EA201100754A1 (es)
EC (1) ECSP11011053A (es)
IL (1) IL211941A0 (es)
MX (1) MX2011005106A (es)
TW (1) TW201022279A (es)
UY (1) UY32247A (es)
WO (1) WO2010055348A1 (es)
ZA (1) ZA201104395B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012275499A1 (en) * 2011-06-27 2013-12-19 Kyorin Pharmaceutical Co., Ltd. Bridged bicyclic compounds for the treatment of bacterial infections
AR096135A1 (es) * 2013-05-02 2015-12-09 Actelion Pharmaceuticals Ltd Derivados de la quinolona
UY36851A (es) * 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
US10029995B2 (en) 2015-09-03 2018-07-24 Forma Therapeutics, Inc. [6,6] fused bicyclic HDAC8 inhibitors
EP3468975B1 (en) * 2016-06-08 2020-04-01 Aziende Chimiche Riunite Angelini Francesco A.C.R. New antibacterial compounds
US10912780B2 (en) 2017-06-08 2021-02-09 Bugworks Research, Inc. Heterocyclic compounds useful as anti-bacterial agents and method for production thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
SG164384A1 (en) * 2006-05-26 2010-09-29 Toyama Chemical Co Ltd Novel heterocyclic compound or salt thereof and intermediate thereof
CL2007003693A1 (es) * 2006-12-22 2008-06-27 Actelion Pharmaceuticals Ltd Compuestos derivados de pirido [3,2-b] [1,4] tiazina; composicion farmaceutica que contiene dichos compuestos; y su uso en el tratamiento de infecciones bacterianas.

Also Published As

Publication number Publication date
ZA201104395B (en) 2012-03-28
CU20110108A7 (es) 2012-01-31
BRPI0921148A2 (pt) 2016-02-23
KR20110093797A (ko) 2011-08-18
WO2010055348A1 (en) 2010-05-20
IL211941A0 (en) 2011-06-30
EP2370444A1 (en) 2011-10-05
MX2011005106A (es) 2011-05-30
TW201022279A (en) 2010-06-16
AR074340A1 (es) 2011-01-12
JP2012508789A (ja) 2012-04-12
AU2009315425A1 (en) 2010-05-20
US20110288084A1 (en) 2011-11-24
UY32247A (es) 2010-06-30
EA201100754A1 (ru) 2012-01-30
CN102216308A (zh) 2011-10-12
ECSP11011053A (es) 2011-06-30
CA2742520A1 (en) 2010-05-20
CO6382113A2 (es) 2012-02-15

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)