CN101687887B - 用作抗菌剂的含氮三环化合物 - Google Patents

用作抗菌剂的含氮三环化合物 Download PDF

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Publication number
CN101687887B
CN101687887B CN2008800213034A CN200880021303A CN101687887B CN 101687887 B CN101687887 B CN 101687887B CN 2008800213034 A CN2008800213034 A CN 2008800213034A CN 200880021303 A CN200880021303 A CN 200880021303A CN 101687887 B CN101687887 B CN 101687887B
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CN
China
Prior art keywords
dihydro
methyl
amino
piperidinyl
dione
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Application number
CN2008800213034A
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English (en)
Chinese (zh)
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CN101687887A (zh
Inventor
戴维·E·戴维斯
戴维·T·戴维斯
艾拉里亚·乔达诺
艾伦·J·亨尼西
尼尔·D·皮尔逊
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Glaxo Group Ltd
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Glaxo Group Ltd
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39580226&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101687887(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0707705A external-priority patent/GB0707705D0/en
Priority claimed from GB0720569A external-priority patent/GB0720569D0/en
Priority claimed from GB0805311A external-priority patent/GB0805311D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CN101687887A publication Critical patent/CN101687887A/zh
Application granted granted Critical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CN2008800213034A 2007-04-20 2008-04-16 用作抗菌剂的含氮三环化合物 Active CN101687887B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB0707705.0 2007-04-20
GB0707705A GB0707705D0 (en) 2007-04-20 2007-04-20 Compounds
GB0720569A GB0720569D0 (en) 2007-10-19 2007-10-19 Compounds
GB0720569.3 2007-10-19
GB0805311.8 2008-03-20
GB0805311A GB0805311D0 (en) 2008-03-20 2008-03-20 Compounds
PCT/EP2008/054621 WO2008128942A1 (en) 2007-04-20 2008-04-16 Tricyclic nitrogen containing compounds as antibacterial agents

Publications (2)

Publication Number Publication Date
CN101687887A CN101687887A (zh) 2010-03-31
CN101687887B true CN101687887B (zh) 2012-08-29

Family

ID=39580226

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008800213034A Active CN101687887B (zh) 2007-04-20 2008-04-16 用作抗菌剂的含氮三环化合物

Country Status (31)

Country Link
US (1) US8389524B2 (enExample)
EP (1) EP2137196B1 (enExample)
JP (1) JP5389013B2 (enExample)
KR (1) KR101567096B1 (enExample)
CN (1) CN101687887B (enExample)
AR (1) AR066111A1 (enExample)
AT (1) ATE483717T1 (enExample)
AU (1) AU2008240764C1 (enExample)
BR (1) BRPI0810064B8 (enExample)
CA (1) CA2684659C (enExample)
CL (1) CL2008001122A1 (enExample)
CO (1) CO6251368A2 (enExample)
CR (2) CR11123A (enExample)
CY (1) CY1111248T1 (enExample)
DE (1) DE602008002912D1 (enExample)
DK (1) DK2137196T3 (enExample)
DO (1) DOP2009000240A (enExample)
EA (1) EA015821B1 (enExample)
HR (1) HRP20100574T1 (enExample)
IL (1) IL201204A0 (enExample)
MA (1) MA31324B1 (enExample)
MX (1) MX2009011317A (enExample)
MY (1) MY149347A (enExample)
NZ (1) NZ579877A (enExample)
PE (1) PE20090274A1 (enExample)
PL (1) PL2137196T3 (enExample)
PT (1) PT2137196E (enExample)
SI (1) SI2137196T1 (enExample)
TW (1) TWI431006B (enExample)
UY (1) UY31038A1 (enExample)
WO (1) WO2008128942A1 (enExample)

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BR112023015676A2 (pt) 2021-02-05 2023-10-17 Glaxosmithkline Ip Dev Ltd Formulações orais em dose sólida
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Also Published As

Publication number Publication date
BRPI0810064B8 (pt) 2021-05-25
JP2010524884A (ja) 2010-07-22
KR20100017133A (ko) 2010-02-16
NZ579877A (en) 2011-09-30
US20100137282A1 (en) 2010-06-03
IL201204A0 (en) 2010-05-17
TW200848420A (en) 2008-12-16
AU2008240764A1 (en) 2008-10-30
KR101567096B1 (ko) 2015-11-06
CY1111248T1 (el) 2015-06-11
EP2137196A1 (en) 2009-12-30
AU2008240764B2 (en) 2011-04-07
DK2137196T3 (da) 2011-01-10
AU2008240764C1 (en) 2011-10-20
EP2137196B1 (en) 2010-10-06
DOP2009000240A (es) 2009-12-31
BRPI0810064B1 (pt) 2021-03-30
CO6251368A2 (es) 2011-02-21
PT2137196E (pt) 2010-12-16
TWI431006B (zh) 2014-03-21
DE602008002912D1 (de) 2010-11-18
BRPI0810064A2 (pt) 2019-08-27
PE20090274A1 (es) 2009-04-03
CN101687887A (zh) 2010-03-31
PL2137196T3 (pl) 2011-03-31
CA2684659A1 (en) 2008-10-30
ATE483717T1 (de) 2010-10-15
CA2684659C (en) 2015-11-24
MX2009011317A (es) 2009-11-05
HRP20100574T1 (hr) 2010-12-31
HK1138000A1 (en) 2010-08-13
SI2137196T1 (sl) 2011-01-31
MA31324B1 (fr) 2010-04-01
UY31038A1 (es) 2008-11-28
MY149347A (en) 2013-08-30
EA200970987A1 (ru) 2010-04-30
CR11123A (es) 2010-03-08
JP5389013B2 (ja) 2014-01-15
AR066111A1 (es) 2009-07-22
CR20150586A (es) 2016-04-04
CL2008001122A1 (es) 2008-10-24
WO2008128942A1 (en) 2008-10-30
US8389524B2 (en) 2013-03-05
EA015821B1 (ru) 2011-12-30

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