BRPI0809977A2 - Uso de um composto, compostos e composição farmacêutica que o contém - Google Patents

Uso de um composto, compostos e composição farmacêutica que o contém

Info

Publication number
BRPI0809977A2
BRPI0809977A2 BRPI0809977-4A2A BRPI0809977A BRPI0809977A2 BR PI0809977 A2 BRPI0809977 A2 BR PI0809977A2 BR PI0809977 A BRPI0809977 A BR PI0809977A BR PI0809977 A2 BRPI0809977 A2 BR PI0809977A2
Authority
BR
Brazil
Prior art keywords
compounds
compound
pharmaceutical composition
composition containing
pharmaceutical
Prior art date
Application number
BRPI0809977-4A2A
Other languages
English (en)
Inventor
Daniel Bur
Christian Hubschwerlen
Georg Rueedi
Jean-Philippe Surivet
Cornelia Zumbrunn-Acklin
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of BRPI0809977A2 publication Critical patent/BRPI0809977A2/pt
Publication of BRPI0809977A8 publication Critical patent/BRPI0809977A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BRPI0809977A 2007-04-11 2008-04-11 Uso de um composto, compostos e composição farmacêutica que o contém BRPI0809977A8 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IB2007051290 2007-04-11
IB2007054587 2007-11-12
IB2007054768 2007-11-23
PCT/IB2008/051374 WO2008126034A2 (en) 2007-04-11 2008-04-11 Oxazolidinone antibiotics

Publications (2)

Publication Number Publication Date
BRPI0809977A2 true BRPI0809977A2 (pt) 2014-10-07
BRPI0809977A8 BRPI0809977A8 (pt) 2017-12-26

Family

ID=39682545

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0809977A BRPI0809977A8 (pt) 2007-04-11 2008-04-11 Uso de um composto, compostos e composição farmacêutica que o contém

Country Status (16)

Country Link
US (1) US8217029B2 (pt)
EP (3) EP2905283B1 (pt)
JP (1) JP5427770B2 (pt)
KR (1) KR101495269B1 (pt)
CN (3) CN102746297B (pt)
AR (1) AR066013A1 (pt)
AU (1) AU2008238904B2 (pt)
BR (1) BRPI0809977A8 (pt)
CA (3) CA2876878C (pt)
CL (1) CL2008001002A1 (pt)
ES (3) ES2557172T3 (pt)
MX (3) MX2009010642A (pt)
PL (3) PL2905283T3 (pt)
RU (1) RU2470022C2 (pt)
TW (1) TWI411434B (pt)
WO (1) WO2008126034A2 (pt)

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BRPI0907892A2 (pt) 2008-02-20 2015-07-28 Actelion Pharmaceuticals Ltd Composto antibiótico azatricíclico, medicamento, composição farmacêutica que o contém e uso do mesmo
CA2713187C (en) 2008-02-22 2016-06-07 Actelion Pharmaceuticals Ltd Oxazolidinone derivatives
WO2010015985A1 (en) 2008-08-04 2010-02-11 Actelion Pharmaceuticals Ltd Tricyclic alkylaminomethyloxazolidinone derivatives
JP4833385B1 (ja) 2008-10-07 2011-12-07 アクテリオン ファーマシューティカルズ リミテッド 三環式オキサゾリジノン抗生物質化合物
ES2395491T3 (es) * 2008-10-10 2013-02-13 Actelion Pharmaceuticals Ltd. 2-Benzotiofenil y 2-naftil-oxazolidinonas y sus análogos azaisósteros como agentes antibacterianos
FR2945533B1 (fr) * 2009-05-12 2011-05-27 Sanofi Aventis Derives de cyclopenta°c!pyrrolyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
EP2388260A1 (de) * 2010-05-21 2011-11-23 Archimica GmbH Herstellungsverfahren für einen Inhibitor eines Blutgerinnungsfaktors
TW201309689A (zh) 2011-02-07 2013-03-01 Daiichi Sankyo Co Ltd 含胺基之吡咯啶酮衍生物
WO2013021363A1 (en) 2011-08-11 2013-02-14 Actelion Pharmaceuticals Ltd Quinazoline-2,4-dione derivatives
IN2014CN04126A (pt) 2011-11-08 2015-07-10 Actelion Pharmaceuticals Ltd
DE102012006884A1 (de) * 2012-04-04 2013-10-10 Merck Patent Gmbh Cyclische Amide als MetAP-2 Inhibitoren
SI2861566T1 (sl) 2012-06-13 2017-03-31 F. Hoffmann-La Roche Ag Novi diazaspirocikloalkan in azaspirocikloalkan
CA2877526A1 (en) 2012-06-20 2013-12-27 Novartis Ag Complement pathway modulators and uses thereof
WO2014024056A1 (en) 2012-08-06 2014-02-13 Daiichi Sankyo Company, Limited Pyrrolidine derivatives with antibacterial properties
PL2900669T3 (pl) 2012-09-25 2020-01-31 F. Hoffmann-La Roche Ag Pochodne heksahydropirolo[3,4-C]pirolu i związki pokrewne jako inhibitory autotaksyny (ATX) oraz inhibitory produkcji kwasu lizofosfatydowego (LPA) do leczenia np. chorób nerek
CN103012389A (zh) * 2013-01-24 2013-04-03 中国药科大学 一种利伐沙班中间体的制备方法
AR095079A1 (es) 2013-03-12 2015-09-16 Hoffmann La Roche Derivados de octahidro-pirrolo[3,4-c]-pirrol y piridina-fenilo
AU2014356583B2 (en) 2013-11-26 2019-02-28 F. Hoffmann-La Roche Ag New octahydro-cyclobuta (1,2-c;3,4-c')dipyrrol-2-yl
MA50635A (fr) 2014-03-26 2020-08-12 Hoffmann La Roche Nouveaux composés bicycliques comme inhibiteurs de la production d'autotaxin (atx) et de l'acide lysophosphatidique
CR20160418A (es) 2014-03-26 2016-11-07 Hoffmann La Roche Nuevos compuestos biciclicos de 7 eslabones
AR102256A1 (es) 2014-10-15 2017-02-15 Actelion Pharmaceuticals Ltd Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi
MA41168A (fr) * 2014-12-17 2017-10-24 Acraf Nouveaux composés antibactériens
MA41898A (fr) 2015-04-10 2018-02-13 Hoffmann La Roche Dérivés de quinazolinone bicyclique
EP3344619B1 (en) 2015-09-04 2020-10-28 H. Hoffnabb-La Roche Ag Phenoxymethyl derivatives
WO2017050747A1 (en) 2015-09-24 2017-03-30 F. Hoffmann-La Roche Ag New bicyclic compounds as dual atx/ca inhibitors
MA42918A (fr) 2015-09-24 2018-08-01 Hoffmann La Roche Composés bicycliques utilisés en tant qu'inhibiteurs d'atx
BR112018006080A2 (pt) 2015-09-24 2018-10-09 F. Hoffmann-La Roche Ag novos compostos bicíclicos como inibidores de dupla ação de atx/ca
AU2016328437A1 (en) 2015-09-24 2018-01-25 F. Hoffmann-La Roche Ag Bicyclic compounds as ATX inhibitors
PL3753929T3 (pl) 2015-12-10 2023-03-13 Bracco Imaging Spa Dimeryczne środki kontrastowe
US10781188B2 (en) 2015-12-10 2020-09-22 Bracco Imaging S.P.A. Contrast agents
MX2021006804A (es) 2015-12-17 2023-01-13 Merck Patent Gmbh Antagonistas policiclicos del receptor 7/8 tipo toll (tlr7/8) y uso de los mismos en el tratamiento de trastornos inmunitarios.
GB201602235D0 (en) * 2016-02-08 2016-03-23 Redx Pharma Plc Antibacterial compounds
CA3012569A1 (en) * 2016-02-08 2017-08-17 Redx Pharma Plc Antibacterial compounds
EP3413976A1 (en) * 2016-02-08 2018-12-19 Redx Pharma PLC Heterocyclic compounds, in particular 2-oxo-4,4,5,5,6,6,7,7-octahydrobenzoxazole derivatives, and their use as antibacterial compounds
JP6909234B2 (ja) 2016-04-13 2021-07-28 ブラッコ・イメージング・ソシエタ・ペル・アチオニＢｒａｃｃｏ Ｉｍａｇｉｎｇ Ｓ．Ｐ．Ａ． 造影剤
AU2017311047B2 (en) 2016-08-08 2021-07-22 Merck Patent Gmbh TLR7/8 antagonists and uses thereof
BR112019011123B1 (pt) 2016-12-12 2024-02-06 Bracco Imaging Spa Agentes de contraste diméricos
TW201833120A (zh) 2017-02-17 2018-09-16 瑞士商愛杜西亞製藥有限公司 芳基噁唑啶酮抗生素化合物
EP3596060B1 (en) 2017-03-16 2023-09-20 F. Hoffmann-La Roche AG New bicyclic compounds as atx inhibitors
RU2019132254A (ru) 2017-03-16 2021-04-16 Ф. Хоффманн-Ля Рош Аг Гетероциклические соединения, пригодные в качестве дуальных ингибиторов atx/ca
WO2019018354A1 (en) 2017-07-18 2019-01-24 Merck Patent Gmbh ANTAGONISTS OF TLR7 / 8 AND USES THEREOF
CN111527093B (zh) * 2017-11-29 2023-06-09 巴格沃克斯研究有限公司 抗菌杂环化合物及其合成
CN109265389B (zh) * 2018-08-31 2020-08-18 南京富润凯德生物医药有限公司 2-(氨基甲基)-1-氧杂-7-氮杂螺[3.5]壬烷衍生物、中间体及其制备方法

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Also Published As

Publication number Publication date
EP2915813B1 (en) 2017-02-01
EP2915813A1 (en) 2015-09-09
PL2144910T3 (pl) 2016-04-29
CN101679415A (zh) 2010-03-24
CA2876878C (en) 2017-07-11
EP2144910A2 (en) 2010-01-20
PL2915813T3 (pl) 2017-07-31
CA2876878A1 (en) 2008-10-23
CN102746297B (zh) 2015-08-26
ES2557172T3 (es) 2016-01-22
US20110039823A1 (en) 2011-02-17
MX351590B (es) 2017-10-20
CN101679415B (zh) 2013-07-31
KR20090130086A (ko) 2009-12-17
EP2905283A1 (en) 2015-08-12
AR066013A1 (es) 2009-07-15
RU2009141311A (ru) 2011-05-20
WO2008126034A2 (en) 2008-10-23
CN102746297A (zh) 2012-10-24
EP2905283B1 (en) 2016-12-14
PL2905283T3 (pl) 2017-06-30
TW200848031A (en) 2008-12-16
RU2470022C2 (ru) 2012-12-20
CA2876879C (en) 2017-11-28
CA2679071C (en) 2016-06-07
CN102746296B (zh) 2015-10-28
KR101495269B1 (ko) 2015-02-26
CA2876879A1 (en) 2008-10-23
ES2622961T3 (es) 2017-07-10
JP5427770B2 (ja) 2014-02-26
JP2010523646A (ja) 2010-07-15
TWI411434B (zh) 2013-10-11
BRPI0809977A8 (pt) 2017-12-26
AU2008238904B2 (en) 2013-11-28
CA2679071A1 (en) 2008-10-23
EP2144910B1 (en) 2015-10-28
CN102746296A (zh) 2012-10-24
WO2008126034A3 (en) 2008-12-31
ES2618492T3 (es) 2017-06-21
MX2009010642A (es) 2009-10-22
CL2008001002A1 (es) 2008-10-17
MX351589B (es) 2017-10-20
US8217029B2 (en) 2012-07-10
AU2008238904A1 (en) 2008-10-23

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25A Requested transfer of rights approved

Owner name: IDORSIA PHARMACEUTICALS LTD (CH)

B25L Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled

Owner name: ACTELION PHARMACEUTICALS LTD (CH)

B25C Requirement related to requested transfer of rights

Owner name: ACTELION PHARMACEUTICALS LTD (CH)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: IDORSIA PHARMACEUTICALS LTD (CH)

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements