MA42918A - Composés bicycliques utilisés en tant qu'inhibiteurs d'atx - Google Patents

Composés bicycliques utilisés en tant qu'inhibiteurs d'atx

Info

Publication number
MA42918A
MA42918A MA042918A MA42918A MA42918A MA 42918 A MA42918 A MA 42918A MA 042918 A MA042918 A MA 042918A MA 42918 A MA42918 A MA 42918A MA 42918 A MA42918 A MA 42918A
Authority
MA
Morocco
Prior art keywords
compounds used
bicyclic compounds
atx inhibitors
atx
inhibitors
Prior art date
Application number
MA042918A
Other languages
English (en)
Inventor
Giorgio Patrick Di
Jérôme Hert
Daniel Hunziker
Patrizio Mattei
Markus Rudolph
Petra Schmitz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA42918A publication Critical patent/MA42918A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
MA042918A 2015-09-24 2016-09-20 Composés bicycliques utilisés en tant qu'inhibiteurs d'atx MA42918A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15186645 2015-09-24

Publications (1)

Publication Number Publication Date
MA42918A true MA42918A (fr) 2018-08-01

Family

ID=54199041

Family Applications (1)

Application Number Title Priority Date Filing Date
MA042918A MA42918A (fr) 2015-09-24 2016-09-20 Composés bicycliques utilisés en tant qu'inhibiteurs d'atx

Country Status (19)

Country Link
US (2) US20180208602A1 (fr)
EP (1) EP3353180B1 (fr)
JP (1) JP6846414B2 (fr)
KR (1) KR20180054830A (fr)
CN (2) CN115124538A (fr)
AR (1) AR106101A1 (fr)
AU (1) AU2016328535A1 (fr)
BR (1) BR112018006024A2 (fr)
CA (1) CA2983782A1 (fr)
CL (1) CL2018000596A1 (fr)
CO (1) CO2017011151A2 (fr)
IL (1) IL255570A (fr)
MA (1) MA42918A (fr)
MX (1) MX2018002217A (fr)
PE (1) PE20180461A1 (fr)
PH (1) PH12018500408A1 (fr)
RU (1) RU2018114289A (fr)
TW (1) TW201720824A (fr)
WO (1) WO2017050732A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
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SI2861566T1 (sl) 2012-06-13 2017-03-31 F. Hoffmann-La Roche Ag Novi diazaspirocikloalkan in azaspirocikloalkan
SG11201500572YA (en) 2012-09-25 2015-02-27 Hoffmann La Roche New bicyclic derivatives
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NO3074400T3 (fr) 2013-11-26 2018-04-14
KR20160128345A (ko) 2014-03-26 2016-11-07 에프. 호프만-라 로슈 아게 오토탁신(atx) 및 리소포스파티드산(lpa) 생성 억제제로서 이환형 화합물
SG11201607845RA (en) 2014-03-26 2016-10-28 Hoffmann La Roche Condensed [1,4]diazepine compounds as autotaxin (atx) and lysophosphatidic acid (lpa) production inhibitors
MA41898A (fr) 2015-04-10 2018-02-13 Hoffmann La Roche Dérivés de quinazolinone bicyclique
JP6886967B2 (ja) 2015-09-04 2021-06-16 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ フェノキシメチル誘導体
EP3353181B1 (fr) 2015-09-24 2021-08-11 F. Hoffmann-La Roche AG Composes bicycliques utiles comme inhibiteurs atx
KR20180054634A (ko) 2015-09-24 2018-05-24 에프. 호프만-라 로슈 아게 이중 오토탁신(atx)/탄산 무수화효소(ca) 억제제로서 신규한 이환형 화합물
JP6876685B2 (ja) 2015-09-24 2021-05-26 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ａｔｘ阻害剤としての二環式化合物
KR20180054830A (ko) 2015-09-24 2018-05-24 에프. 호프만-라 로슈 아게 오토탁신(atx) 억제제로서의 이환형 화합물
EA201891374A1 (ru) 2015-12-10 2018-11-30 Байер Фарма Акциенгезельшафт Замещенные 2-фенил-3-(пиперазинметил)имидазопиридины и их применение
CR20190423A (es) * 2017-03-16 2019-11-01 Hoffmann La Roche Nuevos compuestos biciclícos como inhibidores dobles de atx/ca
CN110382484B (zh) 2017-03-16 2022-12-06 豪夫迈·罗氏有限公司 新的作为atx抑制剂的二环化合物
WO2018227427A1 (fr) 2017-06-14 2018-12-20 Bayer Aktiengesellschaft Dérivés de diazépane pontés substitués et leur utilisation
JOP20190284A1 (ar) 2017-06-14 2019-12-11 Bayer Pharma AG مركبات إيميدازوبيريميدين مستبدلة بديازا ثنائي الحلقة واستخدامها للمعالجة من اضطرابات التنفس
JP2024502337A (ja) 2021-01-05 2024-01-18 ザイダス ライフサイエンシズ リミティド オートタキシンの新規阻害剤

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AR106101A1 (es) 2017-12-13
AU2016328535A1 (en) 2017-11-09
US20180208602A1 (en) 2018-07-26
CN115124538A (zh) 2022-09-30
EP3353180B1 (fr) 2022-03-16
PH12018500408A1 (en) 2018-08-29
CA2983782A1 (fr) 2017-03-30
EP3353180A1 (fr) 2018-08-01
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KR20180054830A (ko) 2018-05-24
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US10787459B2 (en) 2020-09-29
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US20200079779A1 (en) 2020-03-12
TW201720824A (zh) 2017-06-16
WO2017050732A1 (fr) 2017-03-30
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JP6846414B2 (ja) 2021-03-24
BR112018006024A2 (pt) 2020-05-12

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