ATE382623T1 - Octahydropyrrolo(3,4-c)pyrrolderivate und deren verwendung als antivirale mitteln - Google Patents

Octahydropyrrolo(3,4-c)pyrrolderivate und deren verwendung als antivirale mitteln

Info

Publication number
ATE382623T1
ATE382623T1 AT05754708T AT05754708T ATE382623T1 AT E382623 T1 ATE382623 T1 AT E382623T1 AT 05754708 T AT05754708 T AT 05754708T AT 05754708 T AT05754708 T AT 05754708T AT E382623 T1 ATE382623 T1 AT E382623T1
Authority
AT
Austria
Prior art keywords
octahydropyrrolo
antiviral agents
pyrrole derivatives
pyrrole
derivatives
Prior art date
Application number
AT05754708T
Other languages
English (en)
Inventor
Eun Lee
Chris Melville
David Rotstein
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE382623T1 publication Critical patent/ATE382623T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT05754708T 2004-06-09 2005-06-01 Octahydropyrrolo(3,4-c)pyrrolderivate und deren verwendung als antivirale mitteln ATE382623T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57875904P 2004-06-09 2004-06-09

Publications (1)

Publication Number Publication Date
ATE382623T1 true ATE382623T1 (de) 2008-01-15

Family

ID=35431500

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05754708T ATE382623T1 (de) 2004-06-09 2005-06-01 Octahydropyrrolo(3,4-c)pyrrolderivate und deren verwendung als antivirale mitteln

Country Status (21)

Country Link
US (2) US7164019B2 (de)
EP (1) EP1761542B1 (de)
JP (1) JP2008501743A (de)
CN (1) CN101001860A (de)
AR (1) AR049209A1 (de)
AT (1) ATE382623T1 (de)
AU (1) AU2005251891A1 (de)
BR (1) BRPI0511982A (de)
CA (1) CA2569910A1 (de)
DE (1) DE602005004144T2 (de)
DK (1) DK1761542T3 (de)
ES (1) ES2297727T3 (de)
IL (1) IL179534A0 (de)
MX (1) MXPA06014404A (de)
NO (1) NO20070137L (de)
PL (1) PL1761542T3 (de)
PT (1) PT1761542E (de)
RU (1) RU2006146608A (de)
TW (1) TW200701981A (de)
WO (1) WO2005121145A2 (de)
ZA (1) ZA200609837B (de)

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JP6886967B2 (ja) 2015-09-04 2021-06-16 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ フェノキシメチル誘導体
AU2016328365B2 (en) 2015-09-24 2020-04-23 F. Hoffmann-La Roche Ag New bicyclic compounds as dual ATX/CA inhibitors
RU2018112230A (ru) 2015-09-24 2019-10-30 Ф. Хоффманн-Ля Рош Аг Бициклические соединения в качестве ингибиторов atx
CN107635995B (zh) 2015-09-24 2022-08-19 豪夫迈·罗氏有限公司 作为atx抑制剂的二环化合物
JP6877413B2 (ja) 2015-09-24 2021-05-26 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 二重ａｔｘ／ｃａ阻害剤としての新規な二環式化合物
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Also Published As

Publication number Publication date
BRPI0511982A (pt) 2008-01-22
EP1761542A2 (de) 2007-03-14
TW200701981A (en) 2007-01-16
ZA200609837B (en) 2008-09-25
DE602005004144T2 (de) 2009-01-29
WO2005121145A2 (en) 2005-12-22
CN101001860A (zh) 2007-07-18
AR049209A1 (es) 2006-07-05
US20060014767A1 (en) 2006-01-19
CA2569910A1 (en) 2005-12-22
DE602005004144D1 (de) 2008-02-14
DK1761542T3 (da) 2008-04-28
US7714018B2 (en) 2010-05-11
WO2005121145A3 (en) 2006-03-02
US20070117859A1 (en) 2007-05-24
JP2008501743A (ja) 2008-01-24
US7164019B2 (en) 2007-01-16
MXPA06014404A (es) 2007-02-19
AU2005251891A1 (en) 2005-12-22
PT1761542E (pt) 2008-03-26
RU2006146608A (ru) 2008-07-20
PL1761542T3 (pl) 2008-06-30
ES2297727T3 (es) 2008-05-01
EP1761542B1 (de) 2008-01-02
NO20070137L (no) 2007-03-06
IL179534A0 (en) 2007-05-15

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