PL2905283T3 - Pochodne oksazolidynonu - Google Patents

Pochodne oksazolidynonu

Info

Publication number
PL2905283T3
PL2905283T3 PL15154003T PL15154003T PL2905283T3 PL 2905283 T3 PL2905283 T3 PL 2905283T3 PL 15154003 T PL15154003 T PL 15154003T PL 15154003 T PL15154003 T PL 15154003T PL 2905283 T3 PL2905283 T3 PL 2905283T3
Authority
PL
Poland
Prior art keywords
oxazolidinone antibiotics
oxazolidinone
antibiotics
Prior art date
Application number
PL15154003T
Other languages
English (en)
Inventor
Daniel Bur
Christian Hubschwerlen
Georg Rueedi
Jean-Philippe Surivet
Cornelia Zumbrunn
Original Assignee
Actelion Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd. filed Critical Actelion Pharmaceuticals Ltd.
Publication of PL2905283T3 publication Critical patent/PL2905283T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL15154003T 2007-04-11 2008-04-11 Pochodne oksazolidynonu PL2905283T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IB2007051290 2007-04-11
IB2007054587 2007-11-12
IB2007054768 2007-11-23

Publications (1)

Publication Number Publication Date
PL2905283T3 true PL2905283T3 (pl) 2017-06-30

Family

ID=39682545

Family Applications (3)

Application Number Title Priority Date Filing Date
PL08737800T PL2144910T3 (pl) 2007-04-11 2008-04-11 Antybiotyki oksazolidynonowe
PL15154086T PL2915813T3 (pl) 2007-04-11 2008-04-11 Antybiotyki oksazolidynonowe
PL15154003T PL2905283T3 (pl) 2007-04-11 2008-04-11 Pochodne oksazolidynonu

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PL08737800T PL2144910T3 (pl) 2007-04-11 2008-04-11 Antybiotyki oksazolidynonowe
PL15154086T PL2915813T3 (pl) 2007-04-11 2008-04-11 Antybiotyki oksazolidynonowe

Country Status (16)

Country Link
US (1) US8217029B2 (pl)
EP (3) EP2144910B1 (pl)
JP (1) JP5427770B2 (pl)
KR (1) KR101495269B1 (pl)
CN (3) CN102746296B (pl)
AR (1) AR066013A1 (pl)
AU (1) AU2008238904B2 (pl)
BR (1) BRPI0809977A8 (pl)
CA (3) CA2679071C (pl)
CL (1) CL2008001002A1 (pl)
ES (3) ES2622961T3 (pl)
MX (3) MX351589B (pl)
PL (3) PL2144910T3 (pl)
RU (1) RU2470022C2 (pl)
TW (1) TWI411434B (pl)
WO (1) WO2008126034A2 (pl)

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ES2411930T3 (es) 2008-02-20 2013-07-09 Actelion Pharmaceuticals Ltd. Compuestos antibióticos azatricíclicos
RU2501799C2 (ru) 2008-02-22 2013-12-20 Актелион Фармасьютикалз Лтд Поизводные оксазолидинона
ES2399499T3 (es) 2008-08-04 2013-04-01 Actelion Pharmaceuticals Ltd. Derivados de alquilaminometiloxazolidinona tricíclicos
BRPI0920895A8 (pt) 2008-10-07 2017-12-26 Actelion Pharmaceuticals Ltd Compostos antibióticos de oxazolidinona tricíclica
WO2010041219A1 (en) * 2008-10-10 2010-04-15 Actelion Pharmaceuticals Ltd 2-benzothiophenyl-and 2-naphthyl-0xaz0lidin0nes and their azaisostere analogues as antibacterial agents
FR2945533B1 (fr) * 2009-05-12 2011-05-27 Sanofi Aventis Derives de cyclopenta°c!pyrrolyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
EP2388260A1 (de) * 2010-05-21 2011-11-23 Archimica GmbH Herstellungsverfahren für einen Inhibitor eines Blutgerinnungsfaktors
TW201309689A (zh) 2011-02-07 2013-03-01 Daiichi Sankyo Co Ltd 含胺基之吡咯啶酮衍生物
CA2842885A1 (en) 2011-08-11 2013-02-14 Actelion Pharmaceuticals Ltd Quinazoline-2,4-dione derivatives
IN2014CN04126A (pl) 2011-11-08 2015-07-10 Actelion Pharmaceuticals Ltd
DE102012006884A1 (de) * 2012-04-04 2013-10-10 Merck Patent Gmbh Cyclische Amide als MetAP-2 Inhibitoren
IN2014DN09346A (pl) 2012-06-13 2015-07-17 Hoffmann La Roche
JP6163205B2 (ja) 2012-06-20 2017-07-12 ノバルティス アーゲー 補体経路モジュレーターおよびその使用
WO2014024056A1 (en) 2012-08-06 2014-02-13 Daiichi Sankyo Company, Limited Pyrrolidine derivatives with antibacterial properties
KR102179599B1 (ko) 2012-09-25 2020-11-19 에프. 호프만-라 로슈 아게 이환형 유도체
CN103012389A (zh) * 2013-01-24 2013-04-03 中国药科大学 一种利伐沙班中间体的制备方法
AR095079A1 (es) 2013-03-12 2015-09-16 Hoffmann La Roche Derivados de octahidro-pirrolo[3,4-c]-pirrol y piridina-fenilo
CN105764905B (zh) 2013-11-26 2019-06-07 豪夫迈·罗氏有限公司 新的八氢-环丁二烯并[1，2-c；3，4-c’]二吡咯-2基
CN106103446B (zh) 2014-03-26 2019-07-30 豪夫迈·罗氏有限公司 作为自分泌运动因子(atx)和溶血磷脂酸(lpa)生产抑制剂的二环化合物
WO2015144609A1 (en) 2014-03-26 2015-10-01 F. Hoffmann-La Roche Ag Condensed [1,4]diazepine compounds as autotaxin (atx) and lysophosphatidic acid (lpa) production inhibitors
AR102256A1 (es) * 2014-10-15 2017-02-15 Actelion Pharmaceuticals Ltd Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi
MA41168A (fr) * 2014-12-17 2017-10-24 Acraf Nouveaux composés antibactériens
MA41898A (fr) 2015-04-10 2018-02-13 Hoffmann La Roche Dérivés de quinazolinone bicyclique
CA2992889A1 (en) 2015-09-04 2017-03-09 F. Hoffmann-La Roche Ag Phenoxymethyl derivatives
KR20180054830A (ko) 2015-09-24 2018-05-24 에프. 호프만-라 로슈 아게 오토탁신(atx) 억제제로서의 이환형 화합물
CR20180057A (es) 2015-09-24 2018-04-02 Hoffmann La Roche Nuevos compuestos biciclicos como inhibidores duales de atx/ca.
AU2016328365B2 (en) 2015-09-24 2020-04-23 F. Hoffmann-La Roche Ag New bicyclic compounds as dual ATX/CA inhibitors
RU2018112230A (ru) 2015-09-24 2019-10-30 Ф. Хоффманн-Ля Рош Аг Бициклические соединения в качестве ингибиторов atx
US10781188B2 (en) 2015-12-10 2020-09-22 Bracco Imaging S.P.A. Contrast agents
LT3386954T (lt) 2015-12-10 2021-04-12 Bracco Imaging Spa Dimeriniai kontrastiniai agentai
CA3005766A1 (en) 2015-12-17 2017-06-22 Merck Patent Gmbh Polycyclic tlr7/8 antagonists and use thereof in the treatment of immune disorders
EA201891654A1 (ru) * 2016-02-08 2019-01-31 РЭДКС ФАРМА ПиЭлСи Антибактериальные соединения
GB201602235D0 (en) * 2016-02-08 2016-03-23 Redx Pharma Plc Antibacterial compounds
WO2017137743A1 (en) * 2016-02-08 2017-08-17 Redx Pharma Plc Antibacterial compounds
WO2017178301A1 (en) 2016-04-13 2017-10-19 Bracco Imaging Spa Contrast agents
JP7125385B2 (ja) 2016-08-08 2022-08-24 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｔｌｒ７／８アンタゴニストおよびそれらの使用
AU2017375728B2 (en) 2016-12-12 2021-05-27 Bracco Imaging Spa Dimeric contrast agents
TW201833120A (zh) 2017-02-17 2018-09-16 瑞士商愛杜西亞製藥有限公司 芳基噁唑啶酮抗生素化合物
WO2018167113A1 (en) 2017-03-16 2018-09-20 F. Hoffmann-La Roche Ag New bicyclic compounds as atx inhibitors
SG11201908560SA (en) 2017-03-16 2019-10-30 Hoffmann La Roche Heterocyclic compounds useful as dual atx/ca inhibitors
EP3655401B1 (en) * 2017-07-18 2023-09-06 Merck Patent GmbH Tlr7/8 antagonists and uses thereof
WO2019106693A1 (en) * 2017-11-29 2019-06-06 Bugworks Research India Pvt Ltd Anti-bacterial heterocyclic compounds and their synthesis
CN109265389B (zh) * 2018-08-31 2020-08-18 南京富润凯德生物医药有限公司 2-(氨基甲基)-1-氧杂-7-氮杂螺[3.5]壬烷衍生物、中间体及其制备方法

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Also Published As

Publication number Publication date
CA2679071C (en) 2016-06-07
JP5427770B2 (ja) 2014-02-26
WO2008126034A3 (en) 2008-12-31
AU2008238904A1 (en) 2008-10-23
MX351589B (es) 2017-10-20
US8217029B2 (en) 2012-07-10
JP2010523646A (ja) 2010-07-15
AR066013A1 (es) 2009-07-15
CA2679071A1 (en) 2008-10-23
RU2470022C2 (ru) 2012-12-20
BRPI0809977A8 (pt) 2017-12-26
EP2905283A1 (en) 2015-08-12
CA2876879C (en) 2017-11-28
CN101679415A (zh) 2010-03-24
CA2876878A1 (en) 2008-10-23
ES2622961T3 (es) 2017-07-10
EP2915813B1 (en) 2017-02-01
BRPI0809977A2 (pt) 2014-10-07
MX2009010642A (es) 2009-10-22
CN102746296B (zh) 2015-10-28
PL2144910T3 (pl) 2016-04-29
MX351590B (es) 2017-10-20
PL2915813T3 (pl) 2017-07-31
WO2008126034A2 (en) 2008-10-23
CN102746297B (zh) 2015-08-26
ES2618492T3 (es) 2017-06-21
CL2008001002A1 (es) 2008-10-17
CA2876878C (en) 2017-07-11
US20110039823A1 (en) 2011-02-17
CN102746297A (zh) 2012-10-24
KR101495269B1 (ko) 2015-02-26
CN102746296A (zh) 2012-10-24
EP2144910A2 (en) 2010-01-20
EP2905283B1 (en) 2016-12-14
RU2009141311A (ru) 2011-05-20
CA2876879A1 (en) 2008-10-23
CN101679415B (zh) 2013-07-31
EP2915813A1 (en) 2015-09-09
KR20090130086A (ko) 2009-12-17
TWI411434B (zh) 2013-10-11
AU2008238904B2 (en) 2013-11-28
ES2557172T3 (es) 2016-01-22
TW200848031A (en) 2008-12-16
EP2144910B1 (en) 2015-10-28

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