PL2254887T3 - Pochodne oksazolidynonu - Google Patents

Pochodne oksazolidynonu

Info

Publication number
PL2254887T3
PL2254887T3 PL09711588T PL09711588T PL2254887T3 PL 2254887 T3 PL2254887 T3 PL 2254887T3 PL 09711588 T PL09711588 T PL 09711588T PL 09711588 T PL09711588 T PL 09711588T PL 2254887 T3 PL2254887 T3 PL 2254887T3
Authority
PL
Poland
Prior art keywords
oxazolidinone derivatives
oxazolidinone
derivatives
Prior art date
Application number
PL09711588T
Other languages
English (en)
Inventor
Christian Hubschwerlen
Georg Rueedi
Jean-Philippe Surivet
Acklin Cornelia Zumbrunn
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of PL2254887T3 publication Critical patent/PL2254887T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL09711588T 2008-02-22 2009-02-20 Pochodne oksazolidynonu PL2254887T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IB2008050651 2008-02-22
IB2008054095 2008-10-07
EP09711588.5A EP2254887B9 (en) 2008-02-22 2009-02-20 Oxazolidinone derivatives
PCT/IB2009/050702 WO2009104159A1 (en) 2008-02-22 2009-02-20 Oxazolidinone derivatives

Publications (1)

Publication Number Publication Date
PL2254887T3 true PL2254887T3 (pl) 2013-05-31

Family

ID=40578768

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09711588T PL2254887T3 (pl) 2008-02-22 2009-02-20 Pochodne oksazolidynonu

Country Status (14)

Country Link
US (1) US8349826B2 (pl)
EP (1) EP2254887B9 (pl)
JP (1) JP5404652B2 (pl)
KR (1) KR101592046B1 (pl)
CN (1) CN102015698B (pl)
AR (1) AR070458A1 (pl)
BR (1) BRPI0908208A2 (pl)
CA (1) CA2713187C (pl)
ES (1) ES2398939T3 (pl)
MX (1) MX2010008921A (pl)
PL (1) PL2254887T3 (pl)
RU (1) RU2501799C2 (pl)
TW (1) TWI429643B (pl)
WO (1) WO2009104159A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010008922A (es) 2008-02-20 2010-09-07 Actelion Pharmaceuticals Ltd Compuestos antibioticos azatriciclicos.
BRPI0920895A8 (pt) 2008-10-07 2017-12-26 Actelion Pharmaceuticals Ltd Compostos antibióticos de oxazolidinona tricíclica
AU2009302007B2 (en) * 2008-10-10 2015-01-15 Actelion Pharmaceuticals Ltd Oxazolidinyl antibiotics
CN102164915A (zh) * 2008-10-10 2011-08-24 埃科特莱茵药品有限公司 作为抗菌剂的2-苯并噻吩基-和2-萘基-噁唑烷酮及其氮杂等排体类似物
AR076222A1 (es) 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
JPWO2012108376A1 (ja) 2011-02-07 2014-07-03 第一三共株式会社 アミノ基含有ピロリジノン誘導体
RU2014108919A (ru) 2011-08-11 2015-09-20 Актелион Фармасьютиклз Лтд Хиназолин-2,4-дионовые производные
PL2776431T3 (pl) * 2011-11-08 2016-11-30 Stanowiące antybiotyki pochodne 2-okso-oksazolidyno-3,5-diylu
JP2014533747A (ja) 2011-11-30 2014-12-15 アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd 3,7−二置換オクタヒドロ−2H−ピリド[4,3−e][1,3]オキサジン−2−オン抗生物質
WO2014024056A1 (en) 2012-08-06 2014-02-13 Daiichi Sankyo Company, Limited Pyrrolidine derivatives with antibacterial properties
JP2016504408A (ja) 2013-01-09 2016-02-12 アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd 抗菌活性を有するオキサジアゾロン誘導体
PL2986607T3 (pl) 2013-04-16 2017-11-30 Idorsia Pharmaceuticals Ltd Przeciwbakteryjne pochodne biaromatyczne
JP2016518401A (ja) 2013-05-08 2016-06-23 アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd 抗菌活性を有するフタリド誘導体
AR102256A1 (es) 2014-10-15 2017-02-15 Actelion Pharmaceuticals Ltd Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi
GB201602235D0 (en) * 2016-02-08 2016-03-23 Redx Pharma Plc Antibacterial compounds
CA3012569A1 (en) * 2016-02-08 2017-08-17 Redx Pharma Plc Antibacterial compounds
JP2019504850A (ja) * 2016-02-08 2019-02-21 レデックス ファーマ ピーエルシーRedx Pharma Plc 複素環式化合物、特に2−オキソ−4,4,5,5,6,6,7,7−オクタヒドロベンズオキサゾール誘導体、および抗菌化合物としてのこれらの使用
TW201833120A (zh) 2017-02-17 2018-09-16 瑞士商愛杜西亞製藥有限公司 芳基噁唑啶酮抗生素化合物
CN110382505B (zh) * 2017-06-08 2023-04-04 巴格沃克斯研究有限公司 可用作抗菌剂的杂环化合物及其生产方法
WO2019106693A1 (en) 2017-11-29 2019-06-06 Bugworks Research India Pvt Ltd Anti-bacterial heterocyclic compounds and their synthesis
PL3774790T3 (pl) * 2018-03-28 2023-07-31 Bugworks Research, Inc. Oksazolidynonowe związki antybiotykowe oraz sposób ich wytwarzania

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2168696B (en) 1984-12-21 1989-01-11 Boehringer Biochemia Srl Fluoro coumarins as antilymphoedema agents
CA2012681A1 (en) * 1989-03-31 1990-09-30 Masayasu Okuhira Quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
CN1163892A (zh) * 1996-01-16 1997-11-05 拜尔公司 2-氧代-和2-硫代-1,2-二氢喹啉基-噁唑烷酮类化合物
DE19601265A1 (de) * 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
DE19604223A1 (de) * 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
AU1026901A (en) 1999-10-29 2001-05-08 Syngenta Participations Ag Novel herbicides
GB0031086D0 (en) 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
FR2852954B1 (fr) * 2003-03-28 2006-07-14 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
CA2572442A1 (fr) * 2004-07-30 2006-03-09 Palumed S.A. Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
DE602006013878D1 (de) 2005-12-22 2010-06-02 Glaxo Group Ltd Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel
WO2007093904A1 (en) * 2006-02-14 2007-08-23 Pfizer Products Inc. Benzoxazinone and benzoxazepinone oxazolidinones as antibacterial agents
JP5171618B2 (ja) 2006-05-26 2013-03-27 富山化学工業株式会社 新規な複素環化合物またはその塩ならびにその中間体
NZ573706A (en) 2006-06-16 2011-09-30 Pharma Mar Sa Antitumoral dihydropyran-2-one compounds
JP2010511018A (ja) 2006-12-01 2010-04-08 ガラパゴス・ナムローゼ・フェンノートシャップ 変性疾患及び炎症性疾患の治療に有用なトリアゾロピリジン化合物
CL2008001003A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
CL2008001002A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.

Also Published As

Publication number Publication date
TW200940534A (en) 2009-10-01
MX2010008921A (es) 2010-09-07
KR101592046B1 (ko) 2016-02-05
EP2254887A1 (en) 2010-12-01
WO2009104159A1 (en) 2009-08-27
JP2011512401A (ja) 2011-04-21
KR20100124282A (ko) 2010-11-26
TWI429643B (zh) 2014-03-11
RU2501799C2 (ru) 2013-12-20
JP5404652B2 (ja) 2014-02-05
EP2254887B9 (en) 2013-05-29
RU2010138840A (ru) 2012-03-27
CN102015698A (zh) 2011-04-13
ES2398939T3 (es) 2013-03-22
CA2713187C (en) 2016-06-07
AR070458A1 (es) 2010-04-07
ES2398939T9 (es) 2013-07-24
CN102015698B (zh) 2014-08-27
US20100331308A1 (en) 2010-12-30
BRPI0908208A2 (pt) 2015-08-25
EP2254887B1 (en) 2012-12-19
US8349826B2 (en) 2013-01-08
CA2713187A1 (en) 2009-08-27
AU2009215247A1 (en) 2009-08-27

Similar Documents

Publication Publication Date Title
HK1256310A1 (zh) N-磺酰基吡咯衍生物
PL2254887T3 (pl) Pochodne oksazolidynonu
IL210548A0 (en) Spiroaminodihydrothiazine derivatives
EP2376494A4 (en) DIHYDROPYRIMIDOPIRYMIDINE DERIVATIVES
ZA201100799B (en) Imidazopyridin-2-one derivatives
SG10201506608RA (en) 3-deazaneplanocin derivatives
ZA201100876B (en) Pyrrolopyridinylpyrimidin-2-ylamine derivatives
EP2291078A4 (en) OXAZOLBENZIMIDAZOLDERIVATE
ZA201102449B (en) Morpholinopurine derivatives
EP2279532A4 (en) OXAZOLBENZIMIDAZOLDERIVATE
GB0812031D0 (en) Thiazole derivatives
IL210869A0 (en) Imidazothiadiazoles derivatives
IL208336A0 (en) Pyrisazinone derivatives
ZA201100948B (en) Acylaminobenzamide derivatives
IL211290A0 (en) New 2-amidothiadiazole derivatives
IL210164A0 (en) Thiazolylpiperidine derivatives
ZA201005382B (en) Substituted heteroarylamide diazepinopyrimidone derivatives
ZA201005381B (en) Substituted heteroarylamide oxazepinopyrimidone derivatives
ZA201008052B (en) 2-phenyl-4-cyclopropyl-pyrimidine derivatives
IL218696A0 (en) 2-oxo-1- pyrrolidinyl imidazothiadiazole derivatives
ZA201105050B (en) Quinazolinamide derivatives
EP2292613A4 (en) DIHYDROINDOLINONDERIVATE
ZA201005986B (en) Novel heterocycles
IL213051A0 (en) Difluorophenyldiacylhydrazide derivatives
GB2461167B (en) Novel amidoxime derivatives