DE60324179D1 - Chinoline und stickstoffhaltige derivatedavon und deren verwendung als antibakterielle mittel - Google Patents
Chinoline und stickstoffhaltige derivatedavon und deren verwendung als antibakterielle mittelInfo
- Publication number
- DE60324179D1 DE60324179D1 DE60324179T DE60324179T DE60324179D1 DE 60324179 D1 DE60324179 D1 DE 60324179D1 DE 60324179 T DE60324179 T DE 60324179T DE 60324179 T DE60324179 T DE 60324179T DE 60324179 D1 DE60324179 D1 DE 60324179D1
- Authority
- DE
- Germany
- Prior art keywords
- derivatedavan
- nitrogenic
- chinoline
- antibacterial agents
- naphthridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title abstract 3
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43090802P | 2002-12-04 | 2002-12-04 | |
| US46960203P | 2003-05-07 | 2003-05-07 | |
| PCT/US2003/038444 WO2004050036A2 (en) | 2002-12-04 | 2003-12-03 | Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60324179D1 true DE60324179D1 (de) | 2008-11-27 |
Family
ID=32474604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60324179T Expired - Lifetime DE60324179D1 (de) | 2002-12-04 | 2003-12-03 | Chinoline und stickstoffhaltige derivatedavon und deren verwendung als antibakterielle mittel |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7491714B2 (de) |
| EP (1) | EP1567520B1 (de) |
| JP (1) | JP2006515862A (de) |
| AT (1) | ATE411312T1 (de) |
| AU (1) | AU2003294565A1 (de) |
| DE (1) | DE60324179D1 (de) |
| ES (1) | ES2312839T3 (de) |
| WO (1) | WO2004050036A2 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003239302A1 (en) | 2002-01-29 | 2003-09-02 | Glaxo Group Limited | Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them |
| TW200406410A (en) | 2002-01-29 | 2004-05-01 | Glaxo Group Ltd | Compounds |
| AR040335A1 (es) * | 2002-06-26 | 2005-03-30 | Glaxo Group Ltd | Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto |
| TW200409637A (en) | 2002-06-26 | 2004-06-16 | Glaxo Group Ltd | Compounds |
| DE60334016D1 (de) | 2002-11-05 | 2010-10-14 | Glaxo Group Ltd | Antibakterielle mittel |
| EP1560821B8 (de) | 2002-11-05 | 2010-05-19 | Glaxo Group Limited | Antibakterielle wirkstoffe |
| AR042486A1 (es) * | 2002-12-18 | 2005-06-22 | Glaxo Group Ltd | Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion . |
| EP1796466A4 (de) | 2004-06-15 | 2009-09-02 | Glaxo Group Ltd | Antibakterielle mittel |
| WO2006014580A1 (en) * | 2004-07-08 | 2006-02-09 | Glaxo Group Limited | Antibacterial agents |
| US7648984B2 (en) * | 2004-07-13 | 2010-01-19 | Glaxo Group Limited | Antibacterial agents |
| CL2008001002A1 (es) * | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| CL2008001003A1 (es) * | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| EP2245028B1 (de) * | 2007-12-18 | 2012-02-22 | Actelion Pharmaceuticals Ltd. | 5-aminocyclylmethyl-oxazolidin-2-eins-derivative |
| TW201309689A (zh) | 2011-02-07 | 2013-03-01 | Daiichi Sankyo Co Ltd | 含胺基之吡咯啶酮衍生物 |
| WO2014024056A1 (en) | 2012-08-06 | 2014-02-13 | Daiichi Sankyo Company, Limited | Pyrrolidine derivatives with antibacterial properties |
| CN113735770B (zh) * | 2021-09-30 | 2023-06-06 | 四川大学 | 一种铑催化的4-苯基噁二唑酮与碳酸亚乙烯酯合成1-氨基异喹啉骨架的方法 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19601265A1 (de) * | 1996-01-16 | 1997-07-17 | Bayer Ag | 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone |
| ES2201674T3 (es) | 1998-01-26 | 2004-03-16 | Smithkline Beecham Plc | Derivados de quinolina con propiedades antibacterianas. |
| GB9822450D0 (en) | 1998-10-14 | 1998-12-09 | Smithkline Beecham Plc | Medicaments |
| GB9822440D0 (en) | 1998-10-14 | 1998-12-09 | Smithkline Beecham Plc | Medicaments |
| EP1144404A1 (de) | 1999-01-20 | 2001-10-17 | Smithkline Beecham Plc | Piperidinylchinoline als proteintyrosinkinasehemmer |
| GB9914486D0 (en) | 1999-06-21 | 1999-08-18 | Smithkline Beecham Plc | Medicaments |
| GB9917406D0 (en) | 1999-07-23 | 1999-09-22 | Smithkline Beecham Plc | Compounds |
| GB9917408D0 (en) | 1999-07-23 | 1999-09-22 | Smithkline Beecham Plc | Compounds |
| US6403610B1 (en) * | 1999-09-17 | 2002-06-11 | Aventis Pharma S.A. | Quinolylpropylpiperidine derivatives, their preparation and the compositions which comprise them |
| FR2798656B1 (fr) | 1999-09-17 | 2004-12-17 | Aventis Pharma Sa | Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent |
| AU4456601A (en) * | 2000-03-28 | 2001-10-08 | Nippon Soda Co., Ltd. | Oxa(thia)zolidine derivative and anti-inflammatory drug |
| BR0112750A (pt) * | 2000-07-26 | 2003-09-09 | Smithkline Beecham Plc | Aminopiperidina quinolinas e seus análogos azaisostéricos com atividade antibacteriana |
| DE60119939T2 (de) | 2000-09-21 | 2006-11-30 | Smithkline Beecham P.L.C., Brentford | Chinolinderivate als antibakterielle mittel |
| FR2816618B1 (fr) | 2000-11-15 | 2002-12-27 | Aventis Pharma Sa | Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent |
| US6603005B2 (en) * | 2000-11-15 | 2003-08-05 | Aventis Pharma S.A. | Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them |
| GB0031086D0 (en) | 2000-12-20 | 2001-01-31 | Smithkline Beecham Plc | Medicaments |
| GB0031088D0 (en) | 2000-12-20 | 2001-01-31 | Smithkline Beecham Plc | Medicaments |
| ATE319710T1 (de) * | 2000-12-21 | 2006-03-15 | Pharmacia & Upjohn Co Llc | Antimikrobielle chinolonderivate und ihre verwendung zur behandlung bakterieller infektionen |
| GB0101577D0 (en) | 2001-01-22 | 2001-03-07 | Smithkline Beecham Plc | Compounds |
| GB0112834D0 (en) * | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
| AU2003239302A1 (en) | 2002-01-29 | 2003-09-02 | Glaxo Group Limited | Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them |
| TW200406410A (en) | 2002-01-29 | 2004-05-01 | Glaxo Group Ltd | Compounds |
| AR040335A1 (es) | 2002-06-26 | 2005-03-30 | Glaxo Group Ltd | Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto |
| TW200409637A (en) | 2002-06-26 | 2004-06-16 | Glaxo Group Ltd | Compounds |
| GB0217294D0 (en) * | 2002-07-25 | 2002-09-04 | Glaxo Group Ltd | Medicaments |
| EP2239260A1 (de) * | 2002-10-10 | 2010-10-13 | Morphochem Aktiengesellschaft Für Kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
| DE60334016D1 (de) * | 2002-11-05 | 2010-10-14 | Glaxo Group Ltd | Antibakterielle mittel |
| EP1560821B8 (de) | 2002-11-05 | 2010-05-19 | Glaxo Group Limited | Antibakterielle wirkstoffe |
| AR042486A1 (es) | 2002-12-18 | 2005-06-22 | Glaxo Group Ltd | Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion . |
| TW200507841A (en) | 2003-03-27 | 2005-03-01 | Glaxo Group Ltd | Antibacterial agents |
| US7232833B2 (en) * | 2003-03-28 | 2007-06-19 | Novexel | 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them |
| FR2852954B1 (fr) | 2003-03-28 | 2006-07-14 | Aventis Pharma Sa | Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent |
| DE10316081A1 (de) * | 2003-04-08 | 2004-10-21 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
-
2003
- 2003-12-03 AU AU2003294565A patent/AU2003294565A1/en not_active Abandoned
- 2003-12-03 JP JP2004571000A patent/JP2006515862A/ja not_active Ceased
- 2003-12-03 US US10/537,034 patent/US7491714B2/en not_active Expired - Fee Related
- 2003-12-03 ES ES03787253T patent/ES2312839T3/es not_active Expired - Lifetime
- 2003-12-03 EP EP03787253A patent/EP1567520B1/de not_active Expired - Lifetime
- 2003-12-03 DE DE60324179T patent/DE60324179D1/de not_active Expired - Lifetime
- 2003-12-03 WO PCT/US2003/038444 patent/WO2004050036A2/en active Application Filing
- 2003-12-03 AT AT03787253T patent/ATE411312T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2312839T3 (es) | 2009-03-01 |
| JP2006515862A (ja) | 2006-06-08 |
| US7491714B2 (en) | 2009-02-17 |
| WO2004050036A2 (en) | 2004-06-17 |
| ATE411312T1 (de) | 2008-10-15 |
| EP1567520B1 (de) | 2008-10-15 |
| EP1567520A2 (de) | 2005-08-31 |
| US20060116512A1 (en) | 2006-06-01 |
| WO2004050036A3 (en) | 2004-09-02 |
| AU2003294565A8 (en) | 2004-06-23 |
| EP1567520A4 (de) | 2006-08-02 |
| AU2003294565A1 (en) | 2004-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |