ATE255104T1 - Quinolin-derivate und deren verwendung als antibakterielle wirkstoffe - Google Patents

Quinolin-derivate und deren verwendung als antibakterielle wirkstoffe

Info

Publication number
ATE255104T1
ATE255104T1 AT00956221T AT00956221T ATE255104T1 AT E255104 T1 ATE255104 T1 AT E255104T1 AT 00956221 T AT00956221 T AT 00956221T AT 00956221 T AT00956221 T AT 00956221T AT E255104 T1 ATE255104 T1 AT E255104T1
Authority
AT
Austria
Prior art keywords
quinoline derivatives
antibacterial actives
derivatives
actives
antibacterial
Prior art date
Application number
AT00956221T
Other languages
English (en)
Inventor
Roger Edward Markwell
Neil David Pearson
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of ATE255104T1 publication Critical patent/ATE255104T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT00956221T 1999-07-23 2000-07-17 Quinolin-derivate und deren verwendung als antibakterielle wirkstoffe ATE255104T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9917406.2A GB9917406D0 (en) 1999-07-23 1999-07-23 Compounds
PCT/EP2000/006940 WO2001007433A2 (en) 1999-07-23 2000-07-17 Quinoline derivatives and their use as antibacterial agents

Publications (1)

Publication Number Publication Date
ATE255104T1 true ATE255104T1 (de) 2003-12-15

Family

ID=10857875

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00956221T ATE255104T1 (de) 1999-07-23 2000-07-17 Quinolin-derivate und deren verwendung als antibakterielle wirkstoffe

Country Status (9)

Country Link
US (1) US6989447B2 (de)
EP (1) EP1202987B1 (de)
JP (1) JP2003505456A (de)
AT (1) ATE255104T1 (de)
AU (1) AU6825300A (de)
DE (1) DE60006823T2 (de)
ES (1) ES2209955T3 (de)
GB (1) GB9917406D0 (de)
WO (1) WO2001007433A2 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9917408D0 (en) * 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
CZ2003243A3 (cs) 2000-07-26 2003-09-17 Smithkline Beecham P. L. C. Aminopiperidinové chinoliny a jejich azaisosterické analogy s antibakteriální aktivitou
EP1719770A3 (de) * 2000-09-21 2008-03-05 Smithkline Beecham Plc Chinolinderivate als antibakterielle Mittel
GB0031088D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0031086D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) * 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
EP1470125A1 (de) 2002-01-29 2004-10-27 Glaxo Group Limited Aminopiperidinderivate
WO2003064431A2 (en) * 2002-01-29 2003-08-07 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
TW200406413A (en) 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
GB0217294D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicaments
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DE60331849D1 (de) 2002-11-05 2010-05-06 Glaxosmithkline Llc Antibakterielle wirkstoffe
ATE479683T1 (de) 2002-11-05 2010-09-15 Glaxo Group Ltd Antibakterielle mittel
AU2003294565A1 (en) 2002-12-04 2004-06-23 Glaxo Group Limited Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents
TW200427688A (en) * 2002-12-18 2004-12-16 Glaxo Group Ltd Antibacterial agents
US7348434B2 (en) 2003-08-08 2008-03-25 Antony Bigot 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them
FR2858619B1 (fr) * 2003-08-08 2006-12-22 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
FR2867472B1 (fr) * 2004-03-12 2008-07-18 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
US20070254872A1 (en) * 2004-07-08 2007-11-01 Glaxo Group Limited Antibacterial Agents
US7709472B2 (en) 2005-01-25 2010-05-04 Glaxo Group Limited Antibacterial agents
JP2008528598A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
EP1846418A4 (de) 2005-01-25 2009-12-23 Glaxo Group Ltd Antibakterielle wirkstoffe
US7648980B2 (en) 2005-01-25 2010-01-19 Glaxo Group Limited Antibacterial agents
JP2008528604A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
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MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
KR101713472B1 (ko) 2005-09-22 2017-03-07 메이지 세이카 파루마 가부시키가이샤 메탈로-β-락타마제 저해제
CA2635126A1 (en) 2006-01-26 2007-08-02 Actelion Pharmaceuticals Ltd Tetrahydropyrane antibiotics
MX2008010671A (es) * 2006-02-21 2008-10-01 Amgen Inc Derivados de cinolina como inhibidores de fosfodiesterasa 10.
WO2007100880A1 (en) * 2006-02-28 2007-09-07 Amgen Inc. Cinnoline and quinazoline derivates as phosphodiesterase 10 inhibitors
US20070299067A1 (en) * 2006-03-08 2007-12-27 Ruiping Liu Quinoline and isoquinoline derivatives as phosphodiesterase 10 inhibitors
EP2276766A1 (de) 2008-04-15 2011-01-26 Actelion Pharmaceuticals Ltd. Tricyclische antibiotika
USD632242S1 (en) * 2008-08-04 2011-02-08 Rebecca Currie Front seat car bag
US10526343B2 (en) 2018-03-26 2020-01-07 University Of Sharjah Heterocyclic systems and pharmaceutical applications thereof
US20220106308A1 (en) 2019-02-19 2022-04-07 Univerza V Ljubljani Antibacterials based on monocyclic fragments coupled to aminopiperidine naphthyridine scaffold

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FR2177511A1 (en) 1972-03-28 1973-11-09 Omnium Chimique Sa Quinolyl pipiridylethyl ketones - with vasodilatory and antispasmodic activity
GB1496371A (en) * 1975-08-18 1977-12-30 Serdex 4-amino-quinoline derivatives process for their preparation and therapeutic applications thereof
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NL7908031A (nl) 1979-11-01 1981-06-01 Acf Chemiefarma Nv Nieuwe chinolinederivaten en farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werk- wijze voor het bereiden van deze verbindingen.
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HUT76853A (en) 1994-11-14 1997-12-29 Warner Lambert Co 6-aryl pyrido[2,3-d]pyrimidines and naphthyridines for inhibiting protein tyrosine kinase mediated cellular proliferation and pharmaceutical compositions containing the same
KR19990008051A (ko) 1995-04-26 1999-01-25 히라타다다시 라디시콜 유도체
US5620997A (en) 1995-05-31 1997-04-15 Warner-Lambert Company Isothiazolones
GB9514265D0 (en) 1995-07-13 1995-09-13 Wellcome Found Hetrocyclic compounds
US5707990A (en) 1996-01-30 1998-01-13 Ortho Pharmaceutical Corporation 2-substituted amino and thio alkyl benzoxazine antimicrobial agents
AU2898297A (en) 1996-05-24 1998-01-05 Novartis Ag Use of substance p antagonists for treating social phobia
HRP970371A2 (en) 1996-07-13 1998-08-31 Kathryn Jane Smith Heterocyclic compounds
US6057447A (en) * 1996-07-30 2000-05-02 Zenyaku Kogyo Kabushiki Kaisha Quinoline sulfide derivatives
KR19990037220A (ko) 1997-10-31 1999-05-25 타이도 나오카타 아릴아세트산 아미드 유도체 또는 그 염 및 이를 함유하는 의약
DE69908555T2 (de) * 1998-01-26 2004-05-06 Smithkline Beecham P.L.C., Brentford Chinolinderivate als antibakterielles arzneimittel
GB9822450D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9822440D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
FR2798656B1 (fr) 1999-09-17 2004-12-17 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent

Also Published As

Publication number Publication date
EP1202987A2 (de) 2002-05-08
ES2209955T3 (es) 2004-07-01
JP2003505456A (ja) 2003-02-12
DE60006823T2 (de) 2004-08-12
EP1202987B1 (de) 2003-11-26
GB9917406D0 (en) 1999-09-22
AU6825300A (en) 2001-02-13
US6989447B2 (en) 2006-01-24
WO2001007433A3 (en) 2001-05-25
WO2001007433A2 (en) 2001-02-01
US20040116452A1 (en) 2004-06-17
DE60006823D1 (de) 2004-01-08

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties