ATE255104T1 - Quinolin-derivate und deren verwendung als antibakterielle wirkstoffe - Google Patents

Quinolin-derivate und deren verwendung als antibakterielle wirkstoffe

Info

Publication number
ATE255104T1
ATE255104T1 AT00956221T AT00956221T ATE255104T1 AT E255104 T1 ATE255104 T1 AT E255104T1 AT 00956221 T AT00956221 T AT 00956221T AT 00956221 T AT00956221 T AT 00956221T AT E255104 T1 ATE255104 T1 AT E255104T1
Authority
AT
Austria
Prior art keywords
quinoline derivatives
antibacterial actives
derivatives
actives
antibacterial
Prior art date
Application number
AT00956221T
Other languages
English (en)
Inventor
Roger Edward Markwell
Neil David Pearson
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of ATE255104T1 publication Critical patent/ATE255104T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT00956221T 1999-07-23 2000-07-17 Quinolin-derivate und deren verwendung als antibakterielle wirkstoffe ATE255104T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9917406.2A GB9917406D0 (en) 1999-07-23 1999-07-23 Compounds
PCT/EP2000/006940 WO2001007433A2 (en) 1999-07-23 2000-07-17 Quinoline derivatives and their use as antibacterial agents

Publications (1)

Publication Number Publication Date
ATE255104T1 true ATE255104T1 (de) 2003-12-15

Family

ID=10857875

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00956221T ATE255104T1 (de) 1999-07-23 2000-07-17 Quinolin-derivate und deren verwendung als antibakterielle wirkstoffe

Country Status (9)

Country Link
US (1) US6989447B2 (de)
EP (1) EP1202987B1 (de)
JP (1) JP2003505456A (de)
AT (1) ATE255104T1 (de)
AU (1) AU6825300A (de)
DE (1) DE60006823T2 (de)
ES (1) ES2209955T3 (de)
GB (1) GB9917406D0 (de)
WO (1) WO2001007433A2 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9917408D0 (en) * 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
US6962917B2 (en) * 2000-07-26 2005-11-08 Smithkline Beecham P.L.C. Aminopiperidine quinolines and their azaisosteric analogues with antibacterical activity
EP1719770A3 (de) * 2000-09-21 2008-03-05 Smithkline Beecham Plc Chinolinderivate als antibakterielle Mittel
GB0031086D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0031088D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) * 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
JP4508650B2 (ja) 2002-01-29 2010-07-21 グラクソ グループ リミテッド アミノピペリジン化合物、当該化合物の製法および当該化合物を含有する医薬組成物
EP2181996A1 (de) 2002-01-29 2010-05-05 Glaxo Group Limited Aminopiperidinderivate
TW200406413A (en) 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
GB0217294D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicaments
US6835841B2 (en) 2002-09-13 2004-12-28 Bristol-Myers Squibb Company Asymmetric catalytic hydrogenation process for preparation of chiral cyclic β-aminoesters
US7232832B2 (en) 2002-11-05 2007-06-19 Smithkline Beecham Corporation Antibacterial agents
DE60334016D1 (de) 2002-11-05 2010-10-14 Glaxo Group Ltd Antibakterielle mittel
US7491714B2 (en) 2002-12-04 2009-02-17 Glaxo Group Limited Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents
AR042486A1 (es) * 2002-12-18 2005-06-22 Glaxo Group Ltd Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion .
US7348434B2 (en) 2003-08-08 2008-03-25 Antony Bigot 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them
FR2858619B1 (fr) * 2003-08-08 2006-12-22 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
FR2867472B1 (fr) * 2004-03-12 2008-07-18 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
JP2008505920A (ja) * 2004-07-08 2008-02-28 グラクソ　グループ　リミテッド 抗菌剤
WO2006081264A1 (en) 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
EP1846416A4 (de) 2005-01-25 2009-07-01 Glaxo Group Ltd Antibakterielle wirkstoffe
US7592334B2 (en) 2005-01-25 2009-09-22 Glaxo Group Limited Antibacterial agents
WO2006081179A1 (en) 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
WO2006081289A2 (en) 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
US7842810B2 (en) 2005-03-31 2010-11-30 Janssen Pharmaceutica, Nv Bicyclic pyrazole compounds as antibacterial agents
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
EP1941873A4 (de) 2005-09-22 2012-09-26 Meiji Seika Kaisha Metallo-beta-lactamase-hemmer
CN101374831B (zh) 2006-01-26 2011-04-27 埃科特莱茵药品有限公司 四氢吡喃抗生素
JP2009527562A (ja) * 2006-02-21 2009-07-30 アムゲン インコーポレイティッド ホスホジエステラーゼ１０阻害剤としてのシンノリン誘導体
JP2009528365A (ja) * 2006-02-28 2009-08-06 アムゲン インコーポレイティッド ホスホジエステラーゼ１０阻害剤としてのシンノリン及びキナゾリン誘導体
JP2009529060A (ja) * 2006-03-08 2009-08-13 アムゲン インコーポレイティッド ホスホジエステラーゼ１０阻害剤としてのキノリン及びイソキノリン誘導体
WO2009128019A1 (en) 2008-04-15 2009-10-22 Actelion Pharmaceuticals Ltd Tricyclic antibiotics
US10526343B2 (en) 2018-03-26 2020-01-07 University Of Sharjah Heterocyclic systems and pharmaceutical applications thereof
EP3927703B1 (de) 2019-02-19 2023-04-05 Univerza V Ljubljani Antibakterielle substanzen auf basis monocyclischer fragmente, die mit aminopiperidin-naphthyridin-gerüst gekoppelt sind

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NL7908031A (nl) 1979-11-01 1981-06-01 Acf Chemiefarma Nv Nieuwe chinolinederivaten en farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werk- wijze voor het bereiden van deze verbindingen.
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KR100330553B1 (ko) 1993-10-01 2002-11-27 노파르티스 아게 약물학적활성피리딘유도체및그의제조방법
ATE190978T1 (de) 1994-11-14 2000-04-15 Warner Lambert Co 6-aryl-pyrido(2,3-d)pyrimidine und -naphthyridine zur hemmung der durch protein-tyrosin-kinase hervorgerufenen zellvermehrung
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US5620997A (en) 1995-05-31 1997-04-15 Warner-Lambert Company Isothiazolones
GB9514265D0 (en) 1995-07-13 1995-09-13 Wellcome Found Hetrocyclic compounds
US5707990A (en) 1996-01-30 1998-01-13 Ortho Pharmaceutical Corporation 2-substituted amino and thio alkyl benzoxazine antimicrobial agents
AU2898297A (en) 1996-05-24 1998-01-05 Novartis Ag Use of substance p antagonists for treating social phobia
HRP970371A2 (en) 1996-07-13 1998-08-31 Kathryn Jane Smith Heterocyclic compounds
US6057447A (en) * 1996-07-30 2000-05-02 Zenyaku Kogyo Kabushiki Kaisha Quinoline sulfide derivatives
KR19990037220A (ko) 1997-10-31 1999-05-25 타이도 나오카타 아릴아세트산 아미드 유도체 또는 그 염 및 이를 함유하는 의약
DE69908555T2 (de) * 1998-01-26 2004-05-06 Smithkline Beecham P.L.C., Brentford Chinolinderivate als antibakterielles arzneimittel
GB9822450D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9822440D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
FR2798656B1 (fr) 1999-09-17 2004-12-17 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent

Also Published As

Publication number Publication date
GB9917406D0 (en) 1999-09-22
AU6825300A (en) 2001-02-13
DE60006823T2 (de) 2004-08-12
US20040116452A1 (en) 2004-06-17
DE60006823D1 (de) 2004-01-08
EP1202987B1 (de) 2003-11-26
WO2001007433A3 (en) 2001-05-25
WO2001007433A2 (en) 2001-02-01
US6989447B2 (en) 2006-01-24
ES2209955T3 (es) 2004-07-01
EP1202987A2 (de) 2002-05-08
JP2003505456A (ja) 2003-02-12

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties