ATE312831T1 - Chinolin-derivate und ihre verwendung als antibakterielle wirkstoffe - Google Patents
Chinolin-derivate und ihre verwendung als antibakterielle wirkstoffeInfo
- Publication number
- ATE312831T1 ATE312831T1 AT99950730T AT99950730T ATE312831T1 AT E312831 T1 ATE312831 T1 AT E312831T1 AT 99950730 T AT99950730 T AT 99950730T AT 99950730 T AT99950730 T AT 99950730T AT E312831 T1 ATE312831 T1 AT E312831T1
- Authority
- AT
- Austria
- Prior art keywords
- quinoline derivatives
- antibacterial actives
- derivatives
- actives
- antibacterial
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9822440.5A GB9822440D0 (en) | 1998-10-14 | 1998-10-14 | Medicaments |
| PCT/EP1999/007766 WO2000021952A1 (en) | 1998-10-14 | 1999-10-11 | Quinoline derivatives and their use as antibacterial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE312831T1 true ATE312831T1 (de) | 2005-12-15 |
Family
ID=10840577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99950730T ATE312831T1 (de) | 1998-10-14 | 1999-10-11 | Chinolin-derivate und ihre verwendung als antibakterielle wirkstoffe |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6602882B1 (de) |
| EP (1) | EP1121355B1 (de) |
| JP (1) | JP2002527434A (de) |
| AT (1) | ATE312831T1 (de) |
| AU (1) | AU6339599A (de) |
| DE (1) | DE69928952T2 (de) |
| ES (1) | ES2255306T3 (de) |
| GB (1) | GB9822440D0 (de) |
| MA (1) | MA25009A1 (de) |
| PE (1) | PE20001112A1 (de) |
| WO (1) | WO2000021952A1 (de) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9812644B1 (pt) | 1997-09-15 | 2010-07-13 | quinolonas antimicrobianas, composição farmacêutica e uso das mesmas. | |
| GB9822450D0 (en) * | 1998-10-14 | 1998-12-09 | Smithkline Beecham Plc | Medicaments |
| GB9914486D0 (en) | 1999-06-21 | 1999-08-18 | Smithkline Beecham Plc | Medicaments |
| GB9917408D0 (en) | 1999-07-23 | 1999-09-22 | Smithkline Beecham Plc | Compounds |
| GB9917406D0 (en) | 1999-07-23 | 1999-09-22 | Smithkline Beecham Plc | Compounds |
| SE9902987D0 (sv) | 1999-08-24 | 1999-08-24 | Astra Pharma Prod | Novel compounds |
| US6803369B1 (en) | 2000-07-25 | 2004-10-12 | Smithkline Beecham Corporation | Compounds and methods for the treatment of neoplastic disease |
| AU2001289749B9 (en) | 2000-07-26 | 2004-08-19 | Smithkline Beecham P.L.C. | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity |
| WO2002024684A1 (en) * | 2000-09-21 | 2002-03-28 | Smithkline Beecham P.L.C. | Quinoline derivatives as antibacterials |
| GB0031086D0 (en) * | 2000-12-20 | 2001-01-31 | Smithkline Beecham Plc | Medicaments |
| GB0031088D0 (en) * | 2000-12-20 | 2001-01-31 | Smithkline Beecham Plc | Medicaments |
| GB0101577D0 (en) * | 2001-01-22 | 2001-03-07 | Smithkline Beecham Plc | Compounds |
| GB0104050D0 (en) | 2001-02-19 | 2001-04-04 | Astrazeneca Ab | Chemical compounds |
| GB0107228D0 (en) | 2001-03-22 | 2001-05-16 | Astrazeneca Ab | Chemical compounds |
| GB0112834D0 (en) * | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
| GB0112836D0 (en) | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
| GB0118238D0 (en) * | 2001-07-26 | 2001-09-19 | Smithkline Beecham Plc | Medicaments |
| WO2003037259A2 (en) * | 2001-10-30 | 2003-05-08 | The General Hospital Corporation | Methods for the prevention or treatment of bacterial and fungal infections |
| SE0103818D0 (sv) | 2001-11-15 | 2001-11-15 | Astrazeneca Ab | Chemical compounds |
| JP4445753B2 (ja) | 2002-01-29 | 2010-04-07 | グラクソ グループ リミテッド | アミノピペリジン誘導体 |
| AU2003239302A1 (en) * | 2002-01-29 | 2003-09-02 | Glaxo Group Limited | Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them |
| AR040335A1 (es) | 2002-06-26 | 2005-03-30 | Glaxo Group Ltd | Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto |
| TW200409637A (en) * | 2002-06-26 | 2004-06-16 | Glaxo Group Ltd | Compounds |
| US6900224B2 (en) | 2002-07-31 | 2005-05-31 | The Procter & Gamble Company | Antimicrobial quinolones, their compositions and uses |
| ATE461928T1 (de) * | 2002-11-05 | 2010-04-15 | Glaxosmithkline Llc | Antibakterielle wirkstoffe |
| WO2004041210A2 (en) | 2002-11-05 | 2004-05-21 | Smithkline Beecham Corporation | Antibacterial agents |
| US7491714B2 (en) | 2002-12-04 | 2009-02-17 | Glaxo Group Limited | Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents |
| AR042486A1 (es) * | 2002-12-18 | 2005-06-22 | Glaxo Group Ltd | Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion . |
| EP1603899B1 (de) * | 2003-03-06 | 2009-08-26 | Glaxo Group Limited | Heterozyklische harnstoff-derivate für die behandlung von schmerzen. |
| EP1601665A2 (de) * | 2003-03-07 | 2005-12-07 | Glaxo Group Limited | Harnstoff-derivate und deren verwendung als vanilloidrezeptorantagonisten zur behandlung von schmerzen |
| GB0305426D0 (en) * | 2003-03-08 | 2003-04-16 | Glaxo Group Ltd | Novel compounds |
| FR2867472B1 (fr) * | 2004-03-12 | 2008-07-18 | Aventis Pharma Sa | Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent |
| EP1773831A1 (de) * | 2004-07-08 | 2007-04-18 | Glaxo Group Limited | Antibakterielle mittel |
| US7648980B2 (en) | 2005-01-25 | 2010-01-19 | Glaxo Group Limited | Antibacterial agents |
| WO2006081179A1 (en) | 2005-01-25 | 2006-08-03 | Glaxo Group Limited | Antibacterial agents |
| WO2006081289A2 (en) * | 2005-01-25 | 2006-08-03 | Glaxo Group Limited | Antibacterial agents |
| EP1846417A4 (de) | 2005-01-25 | 2009-12-23 | Glaxo Group Ltd | Antibakterielle wirkstoffe |
| US7592334B2 (en) | 2005-01-25 | 2009-09-22 | Glaxo Group Limited | Antibacterial agents |
| MX2007012234A (es) | 2005-03-31 | 2008-03-18 | Johnson & Johnson | Compuestos de pirazol biciclico como agentes antibacterianos. |
| MY150958A (en) | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| EP1981881B1 (de) | 2006-01-26 | 2011-12-07 | Actelion Pharmaceuticals Ltd. | Tetrahydropyran-antibiotika |
| EP1999125A2 (de) | 2006-03-28 | 2008-12-10 | The Procter and Gamble Company | Kopplungsverfahren zur herstellung von chinolon-zwischenverbindungen |
| ATE507219T1 (de) | 2006-03-28 | 2011-05-15 | Warner Chilcott Co Llc | Malatsalze und polymorphe von (3s,5s)-7-ä3-amino- 5-methyl-piperidinylü-1-cyclopropyl-1,4-dihydro 8-methoxy-4-oxo-3-chinolincarbonsäure |
| MX2009012117A (es) * | 2007-05-09 | 2009-11-23 | Pfizer | Composiciones y derivados heterociclicos sustituidos y su uso farmaceutico como antibacterianos. |
| EP2332939A1 (de) | 2009-11-26 | 2011-06-15 | Æterna Zentaris GmbH | Neuartige Naphthyridinderivate und ihre Verwendung als Kinasehemmer |
| WO2020169593A1 (en) | 2019-02-19 | 2020-08-27 | Univerza V Ljubljani | Antibacterials based on monocyclic fragments coupled to aminopiperidine naphthyridine scaffold |
| TW202128161A (zh) | 2019-10-18 | 2021-08-01 | 美國加利福尼亞大學董事會 | 用於靶向病原性血管之化合物及方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4418299Y1 (de) | 1965-01-16 | 1969-08-07 | ||
| US4472404A (en) | 1982-08-16 | 1984-09-18 | The Dow Chemical Company | 8-Quinolinyl carbamates and their use as urinary tract antimicrobials |
| EP0387510A1 (de) | 1989-02-10 | 1990-09-19 | Bayer Ag | Substituierte 8-Carbamoyloxychinolin-Derivate, Verfahren zu deren Herstellung, sowie deren Verwendung zur Bekämpfung von Schädlingen |
| JPH0495071A (ja) | 1990-08-10 | 1992-03-27 | Kyorin Pharmaceut Co Ltd | カルバミン酸誘導体 |
| JP3169188B2 (ja) * | 1991-01-31 | 2001-05-21 | 杏林製薬株式会社 | カルバミン酸誘導体及びその製造方法 |
| WO1994014801A1 (en) | 1992-12-29 | 1994-07-07 | Smithkline Beecham Plc | Heterocyclic urea derivatives as 5ht2c and 5ht2b antagonists |
| CA2212007C (en) * | 1995-02-02 | 2004-09-14 | Daiichi Pharmaceutical Co., Ltd. | Pyridonecarboxylic acid derivatives substitued by a bicyclic amino group |
| US6008230A (en) | 1995-10-16 | 1999-12-28 | Fujisawa Pharmaceutical Co., Ltd. | Quinoline compounds as H+ -ATPases |
| JP3933244B2 (ja) | 1997-04-04 | 2007-06-20 | 株式会社資生堂 | アルキレンジアミン誘導体及び抗潰瘍剤、抗菌剤 |
| JP2002501061A (ja) * | 1998-01-26 | 2002-01-15 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 抗菌剤用キノリン誘導体 |
| FR2798656B1 (fr) | 1999-09-17 | 2004-12-17 | Aventis Pharma Sa | Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent |
-
1998
- 1998-10-14 GB GBGB9822440.5A patent/GB9822440D0/en not_active Ceased
-
1999
- 1999-10-11 ES ES99950730T patent/ES2255306T3/es not_active Expired - Lifetime
- 1999-10-11 EP EP99950730A patent/EP1121355B1/de not_active Expired - Lifetime
- 1999-10-11 AT AT99950730T patent/ATE312831T1/de not_active IP Right Cessation
- 1999-10-11 US US09/807,341 patent/US6602882B1/en not_active Expired - Fee Related
- 1999-10-11 WO PCT/EP1999/007766 patent/WO2000021952A1/en active IP Right Grant
- 1999-10-11 AU AU63395/99A patent/AU6339599A/en not_active Abandoned
- 1999-10-11 JP JP2000575858A patent/JP2002527434A/ja active Pending
- 1999-10-11 DE DE69928952T patent/DE69928952T2/de not_active Expired - Fee Related
- 1999-10-12 MA MA25816A patent/MA25009A1/fr unknown
- 1999-10-12 PE PE1999001028A patent/PE20001112A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2255306T3 (es) | 2006-06-16 |
| EP1121355A1 (de) | 2001-08-08 |
| US6602882B1 (en) | 2003-08-05 |
| DE69928952T2 (de) | 2007-01-11 |
| AU6339599A (en) | 2000-05-01 |
| MA25009A1 (fr) | 2000-07-01 |
| PE20001112A1 (es) | 2000-10-14 |
| DE69928952D1 (de) | 2006-01-19 |
| WO2000021952A1 (en) | 2000-04-20 |
| EP1121355B1 (de) | 2005-12-14 |
| GB9822440D0 (en) | 1998-12-09 |
| JP2002527434A (ja) | 2002-08-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |