WO2007016610A3 - Antibacterial agents - Google Patents

Antibacterial agents Download PDF

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Publication number
WO2007016610A3
WO2007016610A3 PCT/US2006/030043 US2006030043W WO2007016610A3 WO 2007016610 A3 WO2007016610 A3 WO 2007016610A3 US 2006030043 W US2006030043 W US 2006030043W WO 2007016610 A3 WO2007016610 A3 WO 2007016610A3
Authority
WO
WIPO (PCT)
Prior art keywords
antibacterial agents
quinoxaline
quinoline
mammals
naphthalene
Prior art date
Application number
PCT/US2006/030043
Other languages
French (fr)
Other versions
WO2007016610A2 (en
Inventor
Robert A Daines
Alan T Price
Original Assignee
Glaxo Group Ltd
Robert A Daines
Alan T Price
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Robert A Daines, Alan T Price filed Critical Glaxo Group Ltd
Publication of WO2007016610A2 publication Critical patent/WO2007016610A2/en
Publication of WO2007016610A3 publication Critical patent/WO2007016610A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Naphthalene, quinoline, quinoxaline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.
PCT/US2006/030043 2005-08-02 2006-08-02 Antibacterial agents WO2007016610A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70453805P 2005-08-02 2005-08-02
US60/704,538 2005-08-02

Publications (2)

Publication Number Publication Date
WO2007016610A2 WO2007016610A2 (en) 2007-02-08
WO2007016610A3 true WO2007016610A3 (en) 2007-06-07

Family

ID=37709339

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/030043 WO2007016610A2 (en) 2005-08-02 2006-08-02 Antibacterial agents

Country Status (1)

Country Link
WO (1) WO2007016610A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2008001003A1 (en) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd COMPOUNDS DERIVED FROM OXAZOLIDINONA; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUNDS; AND ITS USE TO PREPARE A MEDICINAL PRODUCT TO TREAT A BACTERIAL INFECTION.
EP2080761A1 (en) 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
TW200940551A (en) 2008-02-20 2009-10-01 Actelion Pharmaceuticals Ltd Azatricyclic antibiotic compounds
WO2009125808A1 (en) * 2008-04-11 2009-10-15 第一三共株式会社 Aminocyclohexyl derivative
WO2009125809A1 (en) * 2008-04-11 2009-10-15 第一三共株式会社 Piperidine derivatives
CA2739373C (en) 2008-10-07 2017-01-24 Christian Hubschwerlen Tricyclic oxazolidinone antibiotic compounds
US20110275661A1 (en) 2008-10-17 2011-11-10 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
MX2011005905A (en) * 2008-12-12 2011-06-20 Actelion Pharmaceuticals Ltd 5-amino-2-(1-hydroxy-ethyl)-tetrahydropyran derivatives.
JP5653935B2 (en) 2009-01-15 2015-01-14 グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ Naphthyridin-2 (1H) -one compounds useful as antibacterial agents
JP2014533747A (en) 2011-11-30 2014-12-15 アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ 3,7-Disubstituted octahydro-2H-pyrido [4,3-e] [1,3] oxazin-2-one antibiotic
AR090844A1 (en) * 2012-04-27 2014-12-10 Actelion Pharmaceuticals Ltd PROCESS TO MANUFACTURE DERIVATIVES OF NAFTIRIDINE
WO2014024056A1 (en) 2012-08-06 2014-02-13 Daiichi Sankyo Company, Limited Pyrrolidine derivatives with antibacterial properties
KR20170043603A (en) 2014-08-22 2017-04-21 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 Tricyclic nitrogen containing compounds for treating neisseria gonorrhoea infection
US9957233B1 (en) 2016-08-05 2018-05-01 Calitor Sciences, Llc Process for preparing substituted quinolin-4-ol compounds
EP3762379A1 (en) 2018-03-07 2021-01-13 Bayer Aktiengesellschaft Identification and use of erk5 inhibitors
EP3927703B1 (en) 2019-02-19 2023-04-05 Univerza V Ljubljani Antibacterials based on monocyclic fragments coupled to aminopiperidine naphthyridine scaffold
CN112961106A (en) * 2021-03-13 2021-06-15 德州学院 Novel synthesis process of 4-hydroxy-6-chloroquinoline
WO2024020068A1 (en) * 2022-07-19 2024-01-25 Ohio State Innovation Foundation Bacterial topoisomerase inhibitors

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004002992A1 (en) * 2002-06-26 2004-01-08 Glaxo Group Limited Compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004002992A1 (en) * 2002-06-26 2004-01-08 Glaxo Group Limited Compounds

Also Published As

Publication number Publication date
WO2007016610A2 (en) 2007-02-08

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