BRPI0607758A2 - processos para a fabricaÇço do composto e para a reduÇço do composto, e, composto - Google Patents

processos para a fabricaÇço do composto e para a reduÇço do composto, e, composto Download PDF

Info

Publication number
BRPI0607758A2
BRPI0607758A2 BRPI0607758-7A BRPI0607758A BRPI0607758A2 BR PI0607758 A2 BRPI0607758 A2 BR PI0607758A2 BR PI0607758 A BRPI0607758 A BR PI0607758A BR PI0607758 A2 BRPI0607758 A2 BR PI0607758A2
Authority
BR
Brazil
Prior art keywords
formula
compound
pyrimidin
chloro
dimethyl
Prior art date
Application number
BRPI0607758-7A
Other languages
English (en)
Portuguese (pt)
Inventor
Peter Schneider
Chouaib Tahtaoui
Martin Braun
Sorana Greiveldinger-Poenaru
Juergen Jaeger
Laurent Schmitt
Original Assignee
Arpida Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arpida Ag filed Critical Arpida Ag
Publication of BRPI0607758A2 publication Critical patent/BRPI0607758A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
BRPI0607758-7A 2005-02-18 2006-02-10 processos para a fabricaÇço do composto e para a reduÇço do composto, e, composto BRPI0607758A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/EP2005/001695 2005-02-18
EP2005001695 2005-02-18
PCT/EP2006/001179 WO2006087140A1 (en) 2005-02-18 2006-02-10 Novell processes for the preparation of a benzofuran

Publications (1)

Publication Number Publication Date
BRPI0607758A2 true BRPI0607758A2 (pt) 2010-03-23

Family

ID=36283919

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0607758-7A BRPI0607758A2 (pt) 2005-02-18 2006-02-10 processos para a fabricaÇço do composto e para a reduÇço do composto, e, composto
BRPI0607797-8A BRPI0607797A2 (pt) 2005-02-18 2006-02-10 processos para a fabricação do composto, e para a desproteção de um composto, e, composto

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0607797-8A BRPI0607797A2 (pt) 2005-02-18 2006-02-10 processos para a fabricação do composto, e para a desproteção de um composto, e, composto

Country Status (22)

Country Link
US (2) US20080161561A1 (enExample)
EP (3) EP1856106A1 (enExample)
JP (2) JP2008530156A (enExample)
KR (2) KR20070106636A (enExample)
CN (4) CN101115746A (enExample)
AU (2) AU2006215785A1 (enExample)
BG (2) BG109937A (enExample)
BR (2) BRPI0607758A2 (enExample)
CA (2) CA2596668A1 (enExample)
CZ (2) CZ2007537A3 (enExample)
EE (2) EE200700051A (enExample)
HU (2) HUP0700604A3 (enExample)
IL (2) IL184404A0 (enExample)
MX (2) MX2007009282A (enExample)
NO (2) NO20073678L (enExample)
NZ (1) NZ556800A (enExample)
RO (2) RO122912B8 (enExample)
RU (2) RU2397980C2 (enExample)
TR (1) TR200705187T1 (enExample)
TW (2) TW200640912A (enExample)
WO (2) WO2006087143A1 (enExample)
ZA (2) ZA200706421B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101115746A (zh) * 2005-02-18 2008-01-30 阿皮德公开股份有限公司 用于制备苯并呋喃的新方法
US7947293B2 (en) 2008-04-08 2011-05-24 Arpida Ag Aqueous pharmaceutical formulation
MX2010011117A (es) * 2008-04-08 2011-02-24 Acino Pharma Ag Formulacion farmaceutica acuosa.
FR2949465B1 (fr) * 2009-09-01 2011-08-12 Pf Medicament Derives chromones, leur procede de preparation et leurs applications therapeutiques
CN110606831A (zh) * 2018-06-14 2019-12-24 上海度德医药科技有限公司 一种Iclaprim的新中间体及其制备方法和应用
CN110818693B (zh) * 2018-08-07 2023-06-02 上海度德医药科技有限公司 一种艾拉普林甲磺酸盐晶型b及其制备方法
CN109988156B (zh) * 2019-03-12 2021-12-28 广东中科药物研究有限公司 一种氨基嘧啶化合物
CN110372746A (zh) * 2019-07-11 2019-10-25 辽宁石油化工大学 一种合成β-胺基膦氧化合物的方法
CN110713483B (zh) * 2019-11-18 2023-04-07 上海医药工业研究院 艾拉普林中间体及艾拉普林的制备方法
CN110724135B (zh) * 2019-11-18 2023-04-28 上海医药工业研究院有限公司 一种艾拉普林中间体及其制备方法
CN110724108B (zh) * 2019-11-18 2023-04-28 上海医药工业研究院有限公司 一种艾拉普林中间体及其制备方法
CN110746361B (zh) * 2019-11-18 2023-04-21 上海医药工业研究院有限公司 一种艾拉普林中间体及其制备方法
CN110790753B (zh) * 2019-11-18 2023-04-07 上海医药工业研究院 艾拉普林对甲苯磺酸盐、其制备方法和应用
CN110818694B (zh) * 2019-11-18 2023-04-21 上海医药工业研究院有限公司 艾拉普林中间体及其应用
CN110642792B (zh) * 2019-11-18 2023-04-21 上海医药工业研究院有限公司 艾拉普林中间体的制备方法
CN113493461A (zh) * 2020-04-01 2021-10-12 上海医药工业研究院 一种七元杂环化合物或其盐、其制备方法及应用
CN117700410B (zh) * 2023-05-20 2025-07-04 山东康诺生物工程有限公司 一种3-(2-氯乙基)-2-甲基-9-羟基-4H-吡啶并[1,2-a]嘧啶-4-酮的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2709634A1 (de) * 1977-03-05 1978-09-07 Basf Ag Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4438267A (en) * 1980-11-11 1984-03-20 Daluge Susan M Monoheteroring compounds and their use
CA2238521C (en) * 1995-12-04 2005-08-16 F. Hoffmann-La Roche Ag Diaminopyrimidines, pharmaceutical compositions containing them and their use as antibacterial
WO2002010156A1 (en) * 2000-07-29 2002-02-07 Arpida Ag Benzofuran derivatives and their use as antibacterial agents
WO2003000657A1 (en) * 2001-06-20 2003-01-03 Daiichi Pharmaceutical Co., Ltd. Diamine derivatives
CN100443482C (zh) * 2003-07-11 2008-12-17 阿皮德公开股份有限公司 苯并呋喃衍生物及其在制备治疗由细菌引起的感染的药物中的用途
WO2005014586A1 (en) * 2003-08-08 2005-02-17 Arpida Ag Novel process for the preparation of 2h-chromenes
CN101115746A (zh) * 2005-02-18 2008-01-30 阿皮德公开股份有限公司 用于制备苯并呋喃的新方法

Also Published As

Publication number Publication date
IL184405A0 (en) 2007-10-31
CN102140094B (zh) 2012-06-06
RO122912B1 (ro) 2010-04-30
AU2006215788B2 (en) 2011-10-20
RO122853B1 (ro) 2010-03-30
MX2007009283A (es) 2008-02-19
NO20073701L (no) 2007-09-03
NZ556800A (en) 2011-01-28
WO2006087140A1 (en) 2006-08-24
HUP0700605A3 (en) 2008-02-28
EE200700051A (et) 2007-12-17
CN102140094A (zh) 2011-08-03
HUP0700605A2 (en) 2008-01-28
RU2007134583A (ru) 2009-03-27
CA2596668A1 (en) 2006-08-24
AU2006215785A1 (en) 2006-08-24
RO122912B8 (ro) 2010-09-30
RU2397980C2 (ru) 2010-08-27
CZ2007537A3 (cs) 2008-02-20
WO2006087143A8 (en) 2008-11-27
JP2008530156A (ja) 2008-08-07
ZA200706422B (en) 2008-09-25
TR200705187T1 (tr) 2007-11-21
KR20070106635A (ko) 2007-11-02
CN101115743A (zh) 2008-01-30
NO20073678L (no) 2007-09-03
MX2007009282A (es) 2008-02-19
BG109937A (bg) 2008-05-30
JP2009505943A (ja) 2009-02-12
US20080161561A1 (en) 2008-07-03
CN101115746A (zh) 2008-01-30
RU2007134584A (ru) 2009-03-27
HUP0700604A2 (en) 2008-01-28
EP1856109A1 (en) 2007-11-21
EP1856106A1 (en) 2007-11-21
IL184404A0 (en) 2007-10-31
ZA200706421B (en) 2008-11-26
EE200700050A (et) 2007-12-17
US20080221324A1 (en) 2008-09-11
KR20070106636A (ko) 2007-11-02
TW200640912A (en) 2006-12-01
CZ2007536A3 (cs) 2008-02-20
BG109938A (bg) 2008-05-30
CN102079727A (zh) 2011-06-01
CN101115743B (zh) 2011-04-13
EP2270003A1 (en) 2011-01-05
HUP0700604A3 (en) 2008-02-28
TW200640914A (en) 2006-12-01
CA2596669A1 (en) 2006-08-24
WO2006087143A1 (en) 2006-08-24
AU2006215788A1 (en) 2006-08-24
BRPI0607797A2 (pt) 2010-10-19

Similar Documents

Publication Publication Date Title
BG109938A (bg) Нови методи за получаване на бензофуран
FI86189C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara rebeccamycinanaloger.
TW201518253A (zh) 吡咯衍生物的結晶及其製造方法
KR20080070062A (ko) 신규 융합 피롤 유도체
Ponnusamy et al. Drug efficacy of novel 3-O-methoxy-4-halo disubstituted 5, 7-dimethoxy chromans; evaluated via DNA gyrase inhibition, bacterial cell wall lesion and antibacterial prospective
EP0680950B1 (en) Propenone derivatives
Anderson et al. Synthesis and murine antineoplastic activity of bis [carbamoyloxymethyl] derivatives of pyrrolo [2, 1-a] isoquinoline
JP3019265B2 (ja) ６―アミノオクタヒドロインドリジントリオールの誘導体
CN110526854B (zh) 一种ɑ,β-不饱和酮衍生物、制备方法及作为药物的用途
Katayama et al. Anti-cancer activities of pyrazolo [1, 5-a] indole derivatives
KR100755625B1 (ko) 신경이완 활성을 갖는 5-(2-(4-(1,2벤즈이소티아졸-3-일)-1-피페라지닐)에틸)-6-클로로-1,3-디히드로-2ｈ-인돌-2-온의 아실 유도체
WO2004092180A1 (ja) フラボン誘導体、その製造法およびそれらを含む医薬
HU208966B (en) Process for producing 6-(substituted amino-propionyl)-forskoline derivatives
JPS6330920B2 (enExample)
EP2379549B1 (en) 7-azaindirubins, 7'-azaindirubins, 7-7'-diazaindirubin and the corresponding 3'-oxime ether derivates: production thereof, their production and use as a medicament
JPH04230385A (ja) 新規なカルバゾール誘導体およびその塩
CN114957182A (zh) 一类含有黄酮骨架结构的usp8抑制剂及其应用
Wang Design, Synthesis and Evaluation of Tryptophan-Maleimide Hybrids as Potential Antibacterial Agents
HK1111996A (en) Novell processes for the preparation of a benzofuran
Kshirsagar et al. Mechanistic insight into the aromatization of cyclic p-quinonemethides to indoles
Evsikova et al. Carbonate derivatives of 14β-hydroxycodeine
JPH01132585A (ja) Ｄｃ−５２誘導体
岡田邦輔 et al. Second Approach to the Construction of a Pentacyclic Ring System for Neosurugatoxin.
JPH11180972A (ja) ジヒドロナフトピラン誘導体
NO317260B1 (no) Aminoantracyklinonderivater, fremgangsmate for deres fremstilling, farmasoytisk preparat inneholdende slike derivater, og deres anvendelse i behandlingen av amyloidose

Legal Events

Date Code Title Description
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

Free format text: SOLICITA-SE A REGULARIZACAO DA PROCURACAO, UMA VEZ QUE BASEADO NO ARTIGO 216 1O DA LPI, O DOCUMENTO DE PROCURACAO DEVE SER APRESENTADO EM SUA FORMA AUTENTICADA; OU SEGUNDO PARECER DA PROCURADORIA MEMO/INPI/PROC/NO 074/93, DEVE CONSTAR UMA DECLARACAO DE VERACIDADE, A QUAL DEVE SER ASSINADA POR UMA PESSOA DEVIDAMENTE AUTORIZADA A REPRESENTAR O INTERESSADO, DEVENDO A MESMA CONSTAR NO INSTRUMENTO DE PROCURACAO, OU NO SEU SUBSTABELECIMENTO.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2161 DE 05/06/2012.