NZ556800A - Novel processes for the preparation of a 2H-chromene (Iclaprim) - Google Patents

Novel processes for the preparation of a 2H-chromene (Iclaprim)

Info

Publication number
NZ556800A
NZ556800A NZ556800A NZ55680006A NZ556800A NZ 556800 A NZ556800 A NZ 556800A NZ 556800 A NZ556800 A NZ 556800A NZ 55680006 A NZ55680006 A NZ 55680006A NZ 556800 A NZ556800 A NZ 556800A
Authority
NZ
New Zealand
Prior art keywords
compound
formula
pyrimidin
dimethyl
dimethoxy
Prior art date
Application number
NZ556800A
Other languages
English (en)
Inventor
Peter Schneider
Chouaib Tahtaoui
Original Assignee
Acino Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acino Pharma Ag filed Critical Acino Pharma Ag
Publication of NZ556800A publication Critical patent/NZ556800A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
NZ556800A 2005-02-18 2006-02-10 Novel processes for the preparation of a 2H-chromene (Iclaprim) NZ556800A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2005001695 2005-02-18
PCT/EP2006/001185 WO2006087143A1 (en) 2005-02-18 2006-02-10 Novel processes for the preparation of a 2h-chromene

Publications (1)

Publication Number Publication Date
NZ556800A true NZ556800A (en) 2011-01-28

Family

ID=36283919

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ556800A NZ556800A (en) 2005-02-18 2006-02-10 Novel processes for the preparation of a 2H-chromene (Iclaprim)

Country Status (22)

Country Link
US (2) US20080161561A1 (enExample)
EP (3) EP1856106A1 (enExample)
JP (2) JP2008530156A (enExample)
KR (2) KR20070106636A (enExample)
CN (4) CN101115746A (enExample)
AU (2) AU2006215785A1 (enExample)
BG (2) BG109937A (enExample)
BR (2) BRPI0607758A2 (enExample)
CA (2) CA2596668A1 (enExample)
CZ (2) CZ2007537A3 (enExample)
EE (2) EE200700051A (enExample)
HU (2) HUP0700604A3 (enExample)
IL (2) IL184404A0 (enExample)
MX (2) MX2007009282A (enExample)
NO (2) NO20073678L (enExample)
NZ (1) NZ556800A (enExample)
RO (2) RO122912B8 (enExample)
RU (2) RU2397980C2 (enExample)
TR (1) TR200705187T1 (enExample)
TW (2) TW200640912A (enExample)
WO (2) WO2006087143A1 (enExample)
ZA (2) ZA200706421B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101115746A (zh) * 2005-02-18 2008-01-30 阿皮德公开股份有限公司 用于制备苯并呋喃的新方法
US7947293B2 (en) 2008-04-08 2011-05-24 Arpida Ag Aqueous pharmaceutical formulation
MX2010011117A (es) * 2008-04-08 2011-02-24 Acino Pharma Ag Formulacion farmaceutica acuosa.
FR2949465B1 (fr) * 2009-09-01 2011-08-12 Pf Medicament Derives chromones, leur procede de preparation et leurs applications therapeutiques
CN110606831A (zh) * 2018-06-14 2019-12-24 上海度德医药科技有限公司 一种Iclaprim的新中间体及其制备方法和应用
CN110818693B (zh) * 2018-08-07 2023-06-02 上海度德医药科技有限公司 一种艾拉普林甲磺酸盐晶型b及其制备方法
CN109988156B (zh) * 2019-03-12 2021-12-28 广东中科药物研究有限公司 一种氨基嘧啶化合物
CN110372746A (zh) * 2019-07-11 2019-10-25 辽宁石油化工大学 一种合成β-胺基膦氧化合物的方法
CN110713483B (zh) * 2019-11-18 2023-04-07 上海医药工业研究院 艾拉普林中间体及艾拉普林的制备方法
CN110724135B (zh) * 2019-11-18 2023-04-28 上海医药工业研究院有限公司 一种艾拉普林中间体及其制备方法
CN110724108B (zh) * 2019-11-18 2023-04-28 上海医药工业研究院有限公司 一种艾拉普林中间体及其制备方法
CN110746361B (zh) * 2019-11-18 2023-04-21 上海医药工业研究院有限公司 一种艾拉普林中间体及其制备方法
CN110790753B (zh) * 2019-11-18 2023-04-07 上海医药工业研究院 艾拉普林对甲苯磺酸盐、其制备方法和应用
CN110818694B (zh) * 2019-11-18 2023-04-21 上海医药工业研究院有限公司 艾拉普林中间体及其应用
CN110642792B (zh) * 2019-11-18 2023-04-21 上海医药工业研究院有限公司 艾拉普林中间体的制备方法
CN113493461A (zh) * 2020-04-01 2021-10-12 上海医药工业研究院 一种七元杂环化合物或其盐、其制备方法及应用
CN117700410B (zh) * 2023-05-20 2025-07-04 山东康诺生物工程有限公司 一种3-(2-氯乙基)-2-甲基-9-羟基-4H-吡啶并[1,2-a]嘧啶-4-酮的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2709634A1 (de) * 1977-03-05 1978-09-07 Basf Ag Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4438267A (en) * 1980-11-11 1984-03-20 Daluge Susan M Monoheteroring compounds and their use
CA2238521C (en) * 1995-12-04 2005-08-16 F. Hoffmann-La Roche Ag Diaminopyrimidines, pharmaceutical compositions containing them and their use as antibacterial
WO2002010156A1 (en) * 2000-07-29 2002-02-07 Arpida Ag Benzofuran derivatives and their use as antibacterial agents
WO2003000657A1 (en) * 2001-06-20 2003-01-03 Daiichi Pharmaceutical Co., Ltd. Diamine derivatives
CN100443482C (zh) * 2003-07-11 2008-12-17 阿皮德公开股份有限公司 苯并呋喃衍生物及其在制备治疗由细菌引起的感染的药物中的用途
WO2005014586A1 (en) * 2003-08-08 2005-02-17 Arpida Ag Novel process for the preparation of 2h-chromenes
CN101115746A (zh) * 2005-02-18 2008-01-30 阿皮德公开股份有限公司 用于制备苯并呋喃的新方法

Also Published As

Publication number Publication date
IL184405A0 (en) 2007-10-31
CN102140094B (zh) 2012-06-06
RO122912B1 (ro) 2010-04-30
AU2006215788B2 (en) 2011-10-20
RO122853B1 (ro) 2010-03-30
MX2007009283A (es) 2008-02-19
NO20073701L (no) 2007-09-03
WO2006087140A1 (en) 2006-08-24
HUP0700605A3 (en) 2008-02-28
EE200700051A (et) 2007-12-17
CN102140094A (zh) 2011-08-03
HUP0700605A2 (en) 2008-01-28
BRPI0607758A2 (pt) 2010-03-23
RU2007134583A (ru) 2009-03-27
CA2596668A1 (en) 2006-08-24
AU2006215785A1 (en) 2006-08-24
RO122912B8 (ro) 2010-09-30
RU2397980C2 (ru) 2010-08-27
CZ2007537A3 (cs) 2008-02-20
WO2006087143A8 (en) 2008-11-27
JP2008530156A (ja) 2008-08-07
ZA200706422B (en) 2008-09-25
TR200705187T1 (tr) 2007-11-21
KR20070106635A (ko) 2007-11-02
CN101115743A (zh) 2008-01-30
NO20073678L (no) 2007-09-03
MX2007009282A (es) 2008-02-19
BG109937A (bg) 2008-05-30
JP2009505943A (ja) 2009-02-12
US20080161561A1 (en) 2008-07-03
CN101115746A (zh) 2008-01-30
RU2007134584A (ru) 2009-03-27
HUP0700604A2 (en) 2008-01-28
EP1856109A1 (en) 2007-11-21
EP1856106A1 (en) 2007-11-21
IL184404A0 (en) 2007-10-31
ZA200706421B (en) 2008-11-26
EE200700050A (et) 2007-12-17
US20080221324A1 (en) 2008-09-11
KR20070106636A (ko) 2007-11-02
TW200640912A (en) 2006-12-01
CZ2007536A3 (cs) 2008-02-20
BG109938A (bg) 2008-05-30
CN102079727A (zh) 2011-06-01
CN101115743B (zh) 2011-04-13
EP2270003A1 (en) 2011-01-05
HUP0700604A3 (en) 2008-02-28
TW200640914A (en) 2006-12-01
CA2596669A1 (en) 2006-08-24
WO2006087143A1 (en) 2006-08-24
AU2006215788A1 (en) 2006-08-24
BRPI0607797A2 (pt) 2010-10-19

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