BR9713141A - Composição farmcêutica processo e kit para o tratamento ou a prevenção de um quadro fisiológico asociado com um distúrbio isquêmico relacionado com trombose e um paciente, uso de quantidades farmaceuticamente efetivas de um composto com atividade anti-xa e de um composto antagonista de agregação de plaquetas, produto contendo estes compostos, e, uso destes compostos. - Google Patents

Composição farmcêutica processo e kit para o tratamento ou a prevenção de um quadro fisiológico asociado com um distúrbio isquêmico relacionado com trombose e um paciente, uso de quantidades farmaceuticamente efetivas de um composto com atividade anti-xa e de um composto antagonista de agregação de plaquetas, produto contendo estes compostos, e, uso destes compostos.

Info

Publication number
BR9713141A
BR9713141A BR9713141-5A BR9713141A BR9713141A BR 9713141 A BR9713141 A BR 9713141A BR 9713141 A BR9713141 A BR 9713141A BR 9713141 A BR9713141 A BR 9713141A
Authority
BR
Brazil
Prior art keywords
compound
compounds
activity
thrombosis
patient
Prior art date
Application number
BR9713141-5A
Other languages
English (en)
Inventor
Andre Uzan
Alain H Curaudeau
Robert J Leadley
Christopher T Dunwiddie
Mark H Perrone
Original Assignee
Rhone Poulenc Rorer Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21861879&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9713141(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer Pharma filed Critical Rhone Poulenc Rorer Pharma
Publication of BR9713141A publication Critical patent/BR9713141A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"COMPOSIçãO FARMACêUTICA, PROCESSO E KIT PARA O TRATAMENTO OU A PREVENçãO DE UM QUADRO FISIOLóGICO ASSOCIADO COM UM DISTúRBIO ISQUêMICO RELACIONADO COM TROMBOSE EM UM PACIENTE, USO DE QUANTIDADES FARMACEUTICAMENTE EFETIVAS DE UM COMPOSTO COM ATIVIDADE ANTI-XA E DE UM COMPOSTO AMTAGONISTA DE AGREGAçãO DE PLAQUETAS, PRODUTO CONTENDO ESTES COMPOSTOS, E, USO DESTES COMPOSTOS". A invenção refere-se a uma composição farmacêutica compreendendo um composto com atividade anti-Xa, um composto antagonista de agregação de plaquetas e um veículo farmaceuticamente aceitável. A invenção também se refere a um processo para o tratamento ou a prevenção de um quadro trombogênico associado com um distúrbio isquêmico relacionado com trombose em um paciente, compreendendo administrar ao referido paciente quantidades farmaceuticamente efetivas de um composto com atividade anti-Xa e o composto antagonista de agregação de plaquetas. Adicionalmente, esta invenção refere-se ao uso de quantidades farmaceuticamente efetivas de um composto com atividade anti-Xa e um composto antagonista de agregação de plaquetas na preparação de um medicamento para o tratamento ou a prevenção de um quadro fisiológico associado com um distúrbio isquêmico relacionado com trombose. Além disso, esta invenção refere-se a uma pluralidade de recipientes separados, sendo que pelo menos um dos referidos recipientes contém um composto com atividade anti-Xa e pelo menos outro dos referidos recipientes contém um composto antagonista de agregação de plaquetas, e sendo que os referidos recipientes contêm, opcionalmente, um veículo farmacêutico.
BR9713141-5A 1996-11-27 1997-11-24 Composição farmcêutica processo e kit para o tratamento ou a prevenção de um quadro fisiológico asociado com um distúrbio isquêmico relacionado com trombose e um paciente, uso de quantidades farmaceuticamente efetivas de um composto com atividade anti-xa e de um composto antagonista de agregação de plaquetas, produto contendo estes compostos, e, uso destes compostos. BR9713141A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3187896P 1996-11-27 1996-11-27
PCT/US1997/021440 WO1998023279A1 (en) 1996-11-27 1997-11-24 PHARMACEUTICAL COMPOSITION COMPRISING A COMPOUND HAVING ANTI-Xa ACTIVITY AND A PLATELET AGGREGATION ANTAGONIST COMPOUND

Publications (1)

Publication Number Publication Date
BR9713141A true BR9713141A (pt) 2000-02-08

Family

ID=21861879

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9713141-5A BR9713141A (pt) 1996-11-27 1997-11-24 Composição farmcêutica processo e kit para o tratamento ou a prevenção de um quadro fisiológico asociado com um distúrbio isquêmico relacionado com trombose e um paciente, uso de quantidades farmaceuticamente efetivas de um composto com atividade anti-xa e de um composto antagonista de agregação de plaquetas, produto contendo estes compostos, e, uso destes compostos.

Country Status (28)

Country Link
US (2) US6103705A (pt)
EP (1) EP0946185B2 (pt)
JP (1) JP4498471B2 (pt)
KR (1) KR100512671B1 (pt)
CN (1) CN1121224C (pt)
AP (1) AP1390A (pt)
AT (1) ATE283062T1 (pt)
AU (1) AU754936B2 (pt)
BG (1) BG64542B1 (pt)
BR (1) BR9713141A (pt)
CA (1) CA2272317C (pt)
CZ (1) CZ298552B6 (pt)
DE (1) DE69731763T3 (pt)
DK (1) DK0946185T4 (pt)
EA (1) EA002475B1 (pt)
ES (1) ES2230624T5 (pt)
HK (1) HK1023504A1 (pt)
HU (1) HUP9903496A3 (pt)
IL (1) IL129877A (pt)
NO (1) NO327740B1 (pt)
OA (1) OA11049A (pt)
PL (1) PL189116B1 (pt)
PT (1) PT946185E (pt)
SI (1) SI0946185T2 (pt)
SK (1) SK286024B6 (pt)
UA (1) UA63929C2 (pt)
WO (1) WO1998023279A1 (pt)
ZA (1) ZA9710691B (pt)

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Also Published As

Publication number Publication date
CZ298552B6 (cs) 2007-10-31
CN1238693A (zh) 1999-12-15
JP4498471B2 (ja) 2010-07-07
HK1023504A1 (en) 2000-09-15
NO992555D0 (no) 1999-05-27
DK0946185T3 (da) 2005-03-21
ZA9710691B (en) 1998-06-12
ES2230624T5 (es) 2010-10-25
KR100512671B1 (ko) 2005-09-07
KR20000057265A (ko) 2000-09-15
AP1390A (en) 2005-04-15
AP9901517A0 (en) 1999-06-30
DE69731763D1 (de) 2004-12-30
CA2272317C (en) 2001-01-30
AU5454698A (en) 1998-06-22
HUP9903496A3 (en) 2001-03-28
JP2001506603A (ja) 2001-05-22
CN1121224C (zh) 2003-09-17
US20020032214A1 (en) 2002-03-14
ATE283062T1 (de) 2004-12-15
DK0946185T4 (da) 2010-08-30
DE69731763T2 (de) 2005-06-30
EA002475B1 (ru) 2002-06-27
PL189116B1 (pl) 2005-06-30
OA11049A (en) 2002-02-18
BG64542B1 (bg) 2005-07-29
SK67399A3 (en) 2000-07-11
SI0946185T1 (en) 2005-06-30
SI0946185T2 (sl) 2010-08-31
IL129877A (en) 2004-08-31
EP0946185B2 (en) 2010-05-05
AU754936B2 (en) 2002-11-28
IL129877A0 (en) 2000-02-29
US6103705A (en) 2000-08-15
SK286024B6 (sk) 2008-01-07
NO992555L (no) 1999-05-27
EP0946185A1 (en) 1999-10-06
UA63929C2 (uk) 2004-02-16
DE69731763T3 (de) 2010-12-30
PT946185E (pt) 2005-02-28
BG103372A (en) 2000-01-31
NO327740B1 (no) 2009-09-14
EP0946185B1 (en) 2004-11-24
EP0946185A4 (en) 2001-06-27
HUP9903496A2 (hu) 2000-10-28
EA199900499A1 (ru) 2000-04-24
WO1998023279A1 (en) 1998-06-04
CZ174299A3 (cs) 1999-09-15
ES2230624T3 (es) 2005-05-01

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