BR9704554A - Utilização de lipídios complexos como adições de estabilização para composições farmacêuticas de misturas de enzimas de digestão - Google Patents

Utilização de lipídios complexos como adições de estabilização para composições farmacêuticas de misturas de enzimas de digestão

Info

Publication number
BR9704554A
BR9704554A BR9704554A BR9704554A BR9704554A BR 9704554 A BR9704554 A BR 9704554A BR 9704554 A BR9704554 A BR 9704554A BR 9704554 A BR9704554 A BR 9704554A BR 9704554 A BR9704554 A BR 9704554A
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
enzyme mixtures
complex lipids
digestion enzyme
stabilizing additions
Prior art date
Application number
BR9704554A
Other languages
English (en)
Other versions
BR9704554B1 (pt
Inventor
Manfred Galle
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of BR9704554A publication Critical patent/BR9704554A/pt
Publication of BR9704554B1 publication Critical patent/BR9704554B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
BRPI9704554-3A 1996-08-28 1997-08-28 utilizaÇço de lipÍdios complexos como adiÇÕes de estabilizaÇço para composiÇÕes farmacÊuticas de misturas de enzimas de digestço, composiÇÕes farmacÊuticas soléveis em Água e kit para preparaÇço de soluÇÕes aquosas. BR9704554B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19634752 1996-08-28
DE19724845A DE19724845A1 (de) 1996-08-28 1997-06-12 Verwendung von komplexen Lipiden als stabilisierende Zusätze zu pharmazeutischen Zubereitungen von Verdauungsenzymgemischen

Publications (2)

Publication Number Publication Date
BR9704554A true BR9704554A (pt) 1998-09-15
BR9704554B1 BR9704554B1 (pt) 2011-12-27

Family

ID=26028823

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9704554-3A BR9704554B1 (pt) 1996-08-28 1997-08-28 utilizaÇço de lipÍdios complexos como adiÇÕes de estabilizaÇço para composiÇÕes farmacÊuticas de misturas de enzimas de digestço, composiÇÕes farmacÊuticas soléveis em Água e kit para preparaÇço de soluÇÕes aquosas.

Country Status (22)

Country Link
US (1) US5993806A (pt)
EP (1) EP0826375B1 (pt)
JP (1) JP4593697B2 (pt)
CN (1) CN1199694C (pt)
AR (1) AR008807A1 (pt)
AT (1) ATE284225T1 (pt)
AU (1) AU722151B2 (pt)
BR (1) BR9704554B1 (pt)
CA (1) CA2213151C (pt)
CZ (1) CZ295329B6 (pt)
DE (2) DE19724845A1 (pt)
DK (1) DK0826375T3 (pt)
EE (1) EE04179B1 (pt)
ES (1) ES2235206T3 (pt)
HK (1) HK1005224A1 (pt)
HU (1) HUP9701437A3 (pt)
NO (1) NO973940L (pt)
NZ (1) NZ328616A (pt)
PL (1) PL190140B1 (pt)
PT (1) PT826375E (pt)
SK (1) SK284639B6 (pt)
TR (1) TR199700872A3 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6074689A (en) * 1998-03-10 2000-06-13 Immucell Corporation Colonic delivery of protein or peptide compositions
KR100367659B1 (ko) * 2000-05-08 2003-01-14 주식회사 바이넥스 선택적 안정화제의 첨가에 따른 자가분해(autolysis)를 통한 고역가 판크레아틴의 제조방법
GB0019118D0 (en) * 2000-08-03 2000-09-27 Danisco Solid phase glycerolysis
RU2299074C2 (ru) * 2000-11-02 2007-05-20 Цилиан Аг Применение полученных из инфузорий ферментов в качестве способствующих пищеварению лекарственных средств
US20030099626A1 (en) * 2001-11-20 2003-05-29 Health Education Corporation Nutrient absorption enhancing compositions and methods
PT1729797E (pt) * 2004-03-22 2008-12-17 Solvay Pharm Gmbh Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos
US7153504B2 (en) * 2004-07-30 2006-12-26 Can Technologies, Inc. Stabilized pancreas product
CA2616062A1 (en) * 2005-07-20 2007-01-25 James S. Brophy Modification of particle morphology to improve product functionality
AU2006274835B2 (en) 2005-07-29 2012-05-24 Abbott Laboratories Gmbh Processes for the manufacture of sterilized pancreatin powder
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
US20110183050A1 (en) * 2006-07-20 2011-07-28 Brophy James S Modification of particle morphology to improve product functionality
US8444967B2 (en) 2010-07-09 2013-05-21 Master Supplements, Inc. Treatment including prebiotic composition for use with probiotics
US20090130063A1 (en) * 2007-11-15 2009-05-21 Solvay Pharmaceuticals Gmbh Process for separating and determining the viral load in a pancreatin sample
DK2391382T3 (da) 2009-01-29 2014-08-25 Nordmark Arzneimittel Gmbh & Co Kg Farmaceutisk præparat indeholdende lipase af bakteriel oprindelse
DE102009006594A1 (de) 2009-01-29 2010-08-05 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutisches Präparat
KR101968457B1 (ko) 2010-10-01 2019-04-11 앨러간 파마슈티컬스 인터내셔널 리미티드 장용 코팅된 저 강도 췌장 리파제 제제
JP2016537387A (ja) 2013-08-09 2016-12-01 アラガン ファーマシューティカルズ インターナショナル リミテッド 経腸投与に適した消化酵素組成物
CN106659773A (zh) * 2013-11-05 2017-05-10 阿勒根制药国际有限公司 高效的胰酶药物组合物
JP2014193909A (ja) * 2014-06-04 2014-10-09 Nordmark Arzneimittel Gmbh & Co Kg 医薬調製物
EP3215181A1 (en) * 2014-11-05 2017-09-13 Abbott Laboratories GmbH Processes for producing compositions with improved safety profile comprising pancreatin and compositions suitable for pharmaceutical use
WO2016126970A1 (en) 2015-02-04 2016-08-11 Abbvie Inc. Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency
DE102015114862A1 (de) * 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutische Zusammensetzung, enthaltend eine bakterielle Lipase
DE102015114857A1 (de) 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Getränk, enthaltend eine pharmazeutische Zusammensetzung

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956483A (en) * 1968-10-24 1976-05-11 Wilson Pharmaceutical & Chemical Corporation Preparing pancreatin
US3991180A (en) * 1972-03-06 1976-11-09 Rohm And Haas Company Stabilization of internally administered pancreatic lipase
DE2512746C3 (de) * 1975-03-22 1980-04-24 Kali-Chemie Pharma Gmbh, 3000 Hannover Verfahren zur Herstellung von keimarmem, faserfreiem Pankreatin
GB1603640A (en) * 1977-07-20 1981-11-25 Gist Brocades Nv Enzyme particles
JPS58148814A (ja) * 1982-03-01 1983-09-05 Fujimoto Seiyaku Kk 消化酵素軟カプセル剤
JPS59169491A (ja) * 1983-03-15 1984-09-25 Duskin Franchise Co Ltd 酵素の安定化法
JPH0229950A (ja) * 1988-07-18 1990-01-31 Nec Corp 光ディスク
JP2679852B2 (ja) * 1989-11-29 1997-11-19 株式会社サム研究所 経口及び局所投与用生物活性蛋白組成物
GB9007052D0 (en) * 1990-03-29 1990-05-30 Skua Investments Ltd Pharmaceutical formulations
RU2093996C1 (ru) * 1991-01-24 1997-10-27 Мартек Корпорейшн Способ добавления в детскую питательную смесь докозагексановой кислоты и арахидоновой кислоты (варианты) и композиция (варианты)
DE4200002A1 (de) * 1992-01-02 1993-07-08 Rudolf V Dipl Chem Dr Noronha Reinigungstablette fuer die zahnprothesen
EP0719133A1 (en) * 1993-09-15 1996-07-03 Unilever Plc Skin care method and composition
JPH09125096A (ja) * 1995-10-30 1997-05-13 Koei Sangyo:Kk 液状天然油脂洗剤

Also Published As

Publication number Publication date
SK115997A3 (en) 1998-07-08
EP0826375B1 (de) 2004-12-08
ES2235206T3 (es) 2005-07-01
DE19724845A1 (de) 1998-03-05
CZ295329B6 (cs) 2005-07-13
TR199700872A2 (xx) 1999-04-21
DK0826375T3 (da) 2005-01-24
AU3530997A (en) 1998-03-05
EE9700249A (et) 1998-04-15
HK1005224A1 (en) 1998-12-31
BR9704554B1 (pt) 2011-12-27
PL190140B1 (pl) 2005-11-30
NZ328616A (en) 1999-01-28
EP0826375A3 (de) 2002-08-14
AR008807A1 (es) 2000-02-23
CN1199694C (zh) 2005-05-04
JP4593697B2 (ja) 2010-12-08
US5993806A (en) 1999-11-30
HU9701437D0 (en) 1997-10-28
CA2213151C (en) 2008-04-01
NO973940L (no) 1998-03-02
PT826375E (pt) 2005-02-28
TR199700872A3 (tr) 1999-04-21
CA2213151A1 (en) 1998-02-28
HUP9701437A3 (en) 2001-03-28
ATE284225T1 (de) 2004-12-15
HUP9701437A2 (hu) 1998-03-30
JPH1077236A (ja) 1998-03-24
PL321825A1 (en) 1998-03-02
EE04179B1 (et) 2003-12-15
EP0826375A2 (de) 1998-03-04
AU722151B2 (en) 2000-07-20
CZ218497A3 (cs) 1998-03-18
DE59712108D1 (de) 2005-01-13
CN1174743A (zh) 1998-03-04
NO973940D0 (no) 1997-08-27
SK284639B6 (sk) 2005-08-04

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Legal Events

Date Code Title Description
FB34 Technical and formal requirements: requirement - article 34 of industrial property law
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/12/2011, OBSERVADAS AS CONDICOES LEGAIS.

B25D Requested change of name of applicant approved
B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time
B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)