EE04179B1 - Liitlipiidide kasutamine stabiliseerivate lisanditena seedeensüümide segude ravimpreparaatides - Google Patents

Liitlipiidide kasutamine stabiliseerivate lisanditena seedeensüümide segude ravimpreparaatides

Info

Publication number
EE04179B1
EE04179B1 EE9700249A EE9700249A EE04179B1 EE 04179 B1 EE04179 B1 EE 04179B1 EE 9700249 A EE9700249 A EE 9700249A EE 9700249 A EE9700249 A EE 9700249A EE 04179 B1 EE04179 B1 EE 04179B1
Authority
EE
Estonia
Prior art keywords
pharmaceutical formulations
digestive enzyme
stabilizing additives
enzyme mixtures
compound lipids
Prior art date
Application number
EE9700249A
Other languages
English (en)
Estonian (et)
Other versions
EE9700249A (et
Inventor
Galle Manfred
Original Assignee
Solvay Pharmaceuticals Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharmaceuticals Gmbh filed Critical Solvay Pharmaceuticals Gmbh
Publication of EE9700249A publication Critical patent/EE9700249A/xx
Publication of EE04179B1 publication Critical patent/EE04179B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
EE9700249A 1996-08-28 1997-08-28 Liitlipiidide kasutamine stabiliseerivate lisanditena seedeensüümide segude ravimpreparaatides EE04179B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19634752 1996-08-28
DE19724845A DE19724845A1 (de) 1996-08-28 1997-06-12 Verwendung von komplexen Lipiden als stabilisierende Zusätze zu pharmazeutischen Zubereitungen von Verdauungsenzymgemischen

Publications (2)

Publication Number Publication Date
EE9700249A EE9700249A (et) 1998-04-15
EE04179B1 true EE04179B1 (et) 2003-12-15

Family

ID=26028823

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700249A EE04179B1 (et) 1996-08-28 1997-08-28 Liitlipiidide kasutamine stabiliseerivate lisanditena seedeensüümide segude ravimpreparaatides

Country Status (22)

Country Link
US (1) US5993806A (xx)
EP (1) EP0826375B1 (xx)
JP (1) JP4593697B2 (xx)
CN (1) CN1199694C (xx)
AR (1) AR008807A1 (xx)
AT (1) ATE284225T1 (xx)
AU (1) AU722151B2 (xx)
BR (1) BR9704554B1 (xx)
CA (1) CA2213151C (xx)
CZ (1) CZ295329B6 (xx)
DE (2) DE19724845A1 (xx)
DK (1) DK0826375T3 (xx)
EE (1) EE04179B1 (xx)
ES (1) ES2235206T3 (xx)
HK (1) HK1005224A1 (xx)
HU (1) HUP9701437A3 (xx)
NO (1) NO973940L (xx)
NZ (1) NZ328616A (xx)
PL (1) PL190140B1 (xx)
PT (1) PT826375E (xx)
SK (1) SK284639B6 (xx)
TR (1) TR199700872A2 (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6074689A (en) * 1998-03-10 2000-06-13 Immucell Corporation Colonic delivery of protein or peptide compositions
KR100367659B1 (ko) * 2000-05-08 2003-01-14 주식회사 바이넥스 선택적 안정화제의 첨가에 따른 자가분해(autolysis)를 통한 고역가 판크레아틴의 제조방법
GB0019118D0 (en) * 2000-08-03 2000-09-27 Danisco Solid phase glycerolysis
IL155515A0 (en) * 2000-11-02 2003-11-23 Cilian Ag Use of enzymes obtained from ciliates as medicaments for promoting digestion
US20030099626A1 (en) * 2001-11-20 2003-05-29 Health Education Corporation Nutrient absorption enhancing compositions and methods
PT1729797E (pt) 2004-03-22 2008-12-17 Solvay Pharm Gmbh Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos
US7153504B2 (en) * 2004-07-30 2006-12-26 Can Technologies, Inc. Stabilized pancreas product
AU2006269855A1 (en) * 2005-07-20 2007-01-25 James S. Brophy Modification of particle morphology to improve product functionality
BRPI0614914A2 (pt) 2005-07-29 2011-04-19 Solvay Pharm Gmbh processos para a fabricação de pó de pancreatina esterilizada
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
US20110183050A1 (en) * 2006-07-20 2011-07-28 Brophy James S Modification of particle morphology to improve product functionality
US8444967B2 (en) 2010-07-09 2013-05-21 Master Supplements, Inc. Treatment including prebiotic composition for use with probiotics
US20090130063A1 (en) * 2007-11-15 2009-05-21 Solvay Pharmaceuticals Gmbh Process for separating and determining the viral load in a pancreatin sample
DE102009006594A1 (de) 2009-01-29 2010-08-05 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutisches Präparat
JP5970189B2 (ja) * 2009-01-29 2016-08-17 ノルドマルク・アルツナイミッテル・ゲゼルシヤフト・ミト・ベシュレンクテル・ハフツング・ウント・コンパニー・コマンデイトゲゼルシヤフト 医薬調製物
CL2011002432A1 (es) 2010-10-01 2012-04-20 Aptalis Pharma Ltd Composicion que comprende al menos una enzima digestiva y al menos un portador, en donde el portador comprende celulosa microcristalina que tiene un tamaño de particulas mayor que 100 um; una forma de dosificacion; el envase que la contiene; un proceso para preparar la composicion; y sus usos.
KR20160087794A (ko) 2013-08-09 2016-07-22 앨러간 파마슈티컬스 인터내셔널 리미티드 장관 투여에 적합한 소화 효소 조성물
CA2915671A1 (en) * 2013-11-05 2015-05-14 Aptalis Pharma Ltd. High potency pancreatin pharmaceutical compositions
JP2014193909A (ja) * 2014-06-04 2014-10-09 Nordmark Arzneimittel Gmbh & Co Kg 医薬調製物
RU2712142C2 (ru) * 2014-11-05 2020-01-24 Эбботт Лабораторис Гмбх Способы получения композиций с улучшенным профилем безопасности, содержащих панкреатин, и композиции, пригодные для фармацевтического применения
WO2016126970A1 (en) 2015-02-04 2016-08-11 Abbvie Inc. Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency
DE102015114862A1 (de) * 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutische Zusammensetzung, enthaltend eine bakterielle Lipase
DE102015114857A1 (de) 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Getränk, enthaltend eine pharmazeutische Zusammensetzung

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956483A (en) * 1968-10-24 1976-05-11 Wilson Pharmaceutical & Chemical Corporation Preparing pancreatin
US3991180A (en) * 1972-03-06 1976-11-09 Rohm And Haas Company Stabilization of internally administered pancreatic lipase
DE2512746C3 (de) * 1975-03-22 1980-04-24 Kali-Chemie Pharma Gmbh, 3000 Hannover Verfahren zur Herstellung von keimarmem, faserfreiem Pankreatin
GB1603640A (en) * 1977-07-20 1981-11-25 Gist Brocades Nv Enzyme particles
JPS58148814A (ja) * 1982-03-01 1983-09-05 Fujimoto Seiyaku Kk 消化酵素軟カプセル剤
JPS59169491A (ja) * 1983-03-15 1984-09-25 Duskin Franchise Co Ltd 酵素の安定化法
JPH0229950A (ja) * 1988-07-18 1990-01-31 Nec Corp 光ディスク
JP2679852B2 (ja) * 1989-11-29 1997-11-19 株式会社サム研究所 経口及び局所投与用生物活性蛋白組成物
GB9007052D0 (en) * 1990-03-29 1990-05-30 Skua Investments Ltd Pharmaceutical formulations
NZ241359A (en) * 1991-01-24 1994-08-26 Martek Corp Supplementation of infant formula by the addition of at least two different polyunsaturated fatty acids obtained from at least two different microbial sources; compositions comprising such oils
DE4200002A1 (de) * 1992-01-02 1993-07-08 Rudolf V Dipl Chem Dr Noronha Reinigungstablette fuer die zahnprothesen
EP0719133A1 (en) * 1993-09-15 1996-07-03 Unilever Plc Skin care method and composition
JPH09125096A (ja) * 1995-10-30 1997-05-13 Koei Sangyo:Kk 液状天然油脂洗剤

Also Published As

Publication number Publication date
ATE284225T1 (de) 2004-12-15
US5993806A (en) 1999-11-30
BR9704554A (pt) 1998-09-15
AU722151B2 (en) 2000-07-20
EP0826375B1 (de) 2004-12-08
NO973940L (no) 1998-03-02
PT826375E (pt) 2005-02-28
HK1005224A1 (en) 1998-12-31
SK284639B6 (sk) 2005-08-04
CN1199694C (zh) 2005-05-04
EP0826375A2 (de) 1998-03-04
CZ218497A3 (cs) 1998-03-18
NO973940D0 (no) 1997-08-27
HUP9701437A2 (hu) 1998-03-30
EE9700249A (et) 1998-04-15
BR9704554B1 (pt) 2011-12-27
ES2235206T3 (es) 2005-07-01
NZ328616A (en) 1999-01-28
SK115997A3 (en) 1998-07-08
AR008807A1 (es) 2000-02-23
CA2213151C (en) 2008-04-01
PL190140B1 (pl) 2005-11-30
AU3530997A (en) 1998-03-05
DE19724845A1 (de) 1998-03-05
EP0826375A3 (de) 2002-08-14
CZ295329B6 (cs) 2005-07-13
TR199700872A3 (tr) 1999-04-21
HU9701437D0 (en) 1997-10-28
CN1174743A (zh) 1998-03-04
TR199700872A2 (xx) 1999-04-21
DE59712108D1 (de) 2005-01-13
CA2213151A1 (en) 1998-02-28
PL321825A1 (en) 1998-03-02
HUP9701437A3 (en) 2001-03-28
JP4593697B2 (ja) 2010-12-08
JPH1077236A (ja) 1998-03-24
DK0826375T3 (da) 2005-01-24

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20031231

KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

MM4A Lapsed by not paying the annual fees

Effective date: 20060828