HK1005224A1 - Use of complex lipide as stabilizing additives in pharmaceutical formulation of digestive enzyme mixture. - Google Patents

Use of complex lipide as stabilizing additives in pharmaceutical formulation of digestive enzyme mixture.

Info

Publication number
HK1005224A1
HK1005224A1 HK98103695A HK98103695A HK1005224A1 HK 1005224 A1 HK1005224 A1 HK 1005224A1 HK 98103695 A HK98103695 A HK 98103695A HK 98103695 A HK98103695 A HK 98103695A HK 1005224 A1 HK1005224 A1 HK 1005224A1
Authority
HK
Hong Kong
Prior art keywords
lipide
complex
pharmaceutical formulation
enzyme mixture
digestive enzyme
Prior art date
Application number
HK98103695A
Other languages
English (en)
Inventor
Manfred Galle
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of HK1005224A1 publication Critical patent/HK1005224A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
HK98103695A 1996-08-28 1998-04-30 Use of complex lipide as stabilizing additives in pharmaceutical formulation of digestive enzyme mixture. HK1005224A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19634752 1996-08-28
DE19724845A DE19724845A1 (de) 1996-08-28 1997-06-12 Verwendung von komplexen Lipiden als stabilisierende Zusätze zu pharmazeutischen Zubereitungen von Verdauungsenzymgemischen

Publications (1)

Publication Number Publication Date
HK1005224A1 true HK1005224A1 (en) 1998-12-31

Family

ID=26028823

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98103695A HK1005224A1 (en) 1996-08-28 1998-04-30 Use of complex lipide as stabilizing additives in pharmaceutical formulation of digestive enzyme mixture.

Country Status (22)

Country Link
US (1) US5993806A (xx)
EP (1) EP0826375B1 (xx)
JP (1) JP4593697B2 (xx)
CN (1) CN1199694C (xx)
AR (1) AR008807A1 (xx)
AT (1) ATE284225T1 (xx)
AU (1) AU722151B2 (xx)
BR (1) BR9704554B1 (xx)
CA (1) CA2213151C (xx)
CZ (1) CZ295329B6 (xx)
DE (2) DE19724845A1 (xx)
DK (1) DK0826375T3 (xx)
EE (1) EE04179B1 (xx)
ES (1) ES2235206T3 (xx)
HK (1) HK1005224A1 (xx)
HU (1) HUP9701437A3 (xx)
NO (1) NO973940L (xx)
NZ (1) NZ328616A (xx)
PL (1) PL190140B1 (xx)
PT (1) PT826375E (xx)
SK (1) SK284639B6 (xx)
TR (1) TR199700872A3 (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6074689A (en) * 1998-03-10 2000-06-13 Immucell Corporation Colonic delivery of protein or peptide compositions
KR100367659B1 (ko) * 2000-05-08 2003-01-14 주식회사 바이넥스 선택적 안정화제의 첨가에 따른 자가분해(autolysis)를 통한 고역가 판크레아틴의 제조방법
GB0019118D0 (en) * 2000-08-03 2000-09-27 Danisco Solid phase glycerolysis
RU2299074C2 (ru) * 2000-11-02 2007-05-20 Цилиан Аг Применение полученных из инфузорий ферментов в качестве способствующих пищеварению лекарственных средств
US20030099626A1 (en) * 2001-11-20 2003-05-29 Health Education Corporation Nutrient absorption enhancing compositions and methods
PT1729797E (pt) 2004-03-22 2008-12-17 Solvay Pharm Gmbh Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos
US7153504B2 (en) * 2004-07-30 2006-12-26 Can Technologies, Inc. Stabilized pancreas product
WO2007012069A2 (en) * 2005-07-20 2007-01-25 Brophy James S Modification of particle morphology to improve product functionality
CA2616943C (en) 2005-07-29 2016-04-12 Solvay Pharmaceuticals Gmbh Processes for the manufacture of sterilized pancreatin powder
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
US20110183050A1 (en) * 2006-07-20 2011-07-28 Brophy James S Modification of particle morphology to improve product functionality
US8444967B2 (en) 2010-07-09 2013-05-21 Master Supplements, Inc. Treatment including prebiotic composition for use with probiotics
US20090130063A1 (en) * 2007-11-15 2009-05-21 Solvay Pharmaceuticals Gmbh Process for separating and determining the viral load in a pancreatin sample
PL2391382T3 (pl) 2009-01-29 2014-11-28 Nordmark Arzneimittel Gmbh & Co Kg Preparat farmaceutyczny zawierający lipazę pochodzenia bakteryjnego
DE102009006594A1 (de) 2009-01-29 2010-08-05 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutisches Präparat
CN103221036A (zh) 2010-10-01 2013-07-24 阿普塔利斯制药有限公司 肠溶包衣的低强度胰脂肪酶制剂
CA2920844A1 (en) 2013-08-09 2015-02-12 Allergan Pharmaceuticals International Limited Digestive enzyme composition suitable for enteral administration
EP3613429A1 (en) * 2013-11-05 2020-02-26 Allergan Pharmaceuticals International Limited High potency pancreatin pharmaceutical compositions
JP2014193909A (ja) * 2014-06-04 2014-10-09 Nordmark Arzneimittel Gmbh & Co Kg 医薬調製物
RU2712142C2 (ru) * 2014-11-05 2020-01-24 Эбботт Лабораторис Гмбх Способы получения композиций с улучшенным профилем безопасности, содержащих панкреатин, и композиции, пригодные для фармацевтического применения
US20180028454A1 (en) 2015-02-04 2018-02-01 Abbvie Inc. Pharmaceutical compositions and methods of use thereof to treat pancreatic enzyme insufficiency
DE102015114862A1 (de) * 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Pharmazeutische Zusammensetzung, enthaltend eine bakterielle Lipase
DE102015114857A1 (de) 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Getränk, enthaltend eine pharmazeutische Zusammensetzung

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956483A (en) * 1968-10-24 1976-05-11 Wilson Pharmaceutical & Chemical Corporation Preparing pancreatin
US3991180A (en) * 1972-03-06 1976-11-09 Rohm And Haas Company Stabilization of internally administered pancreatic lipase
DE2512746C3 (de) * 1975-03-22 1980-04-24 Kali-Chemie Pharma Gmbh, 3000 Hannover Verfahren zur Herstellung von keimarmem, faserfreiem Pankreatin
GB1603640A (en) * 1977-07-20 1981-11-25 Gist Brocades Nv Enzyme particles
JPS58148814A (ja) * 1982-03-01 1983-09-05 Fujimoto Seiyaku Kk 消化酵素軟カプセル剤
JPS59169491A (ja) * 1983-03-15 1984-09-25 Duskin Franchise Co Ltd 酵素の安定化法
JPH0229950A (ja) * 1988-07-18 1990-01-31 Nec Corp 光ディスク
JP2679852B2 (ja) * 1989-11-29 1997-11-19 株式会社サム研究所 経口及び局所投与用生物活性蛋白組成物
GB9007052D0 (en) * 1990-03-29 1990-05-30 Skua Investments Ltd Pharmaceutical formulations
NZ241359A (en) * 1991-01-24 1994-08-26 Martek Corp Supplementation of infant formula by the addition of at least two different polyunsaturated fatty acids obtained from at least two different microbial sources; compositions comprising such oils
DE4200002A1 (de) * 1992-01-02 1993-07-08 Rudolf V Dipl Chem Dr Noronha Reinigungstablette fuer die zahnprothesen
WO1995007688A1 (en) * 1993-09-15 1995-03-23 Unilever Plc Skin care method and composition
JPH09125096A (ja) * 1995-10-30 1997-05-13 Koei Sangyo:Kk 液状天然油脂洗剤

Also Published As

Publication number Publication date
ES2235206T3 (es) 2005-07-01
DE59712108D1 (de) 2005-01-13
EE04179B1 (et) 2003-12-15
JPH1077236A (ja) 1998-03-24
HU9701437D0 (en) 1997-10-28
EP0826375A2 (de) 1998-03-04
US5993806A (en) 1999-11-30
HUP9701437A3 (en) 2001-03-28
BR9704554A (pt) 1998-09-15
EE9700249A (et) 1998-04-15
SK284639B6 (sk) 2005-08-04
SK115997A3 (en) 1998-07-08
EP0826375A3 (de) 2002-08-14
DE19724845A1 (de) 1998-03-05
BR9704554B1 (pt) 2011-12-27
EP0826375B1 (de) 2004-12-08
CN1174743A (zh) 1998-03-04
PL190140B1 (pl) 2005-11-30
ATE284225T1 (de) 2004-12-15
TR199700872A2 (xx) 1999-04-21
NO973940L (no) 1998-03-02
PL321825A1 (en) 1998-03-02
NZ328616A (en) 1999-01-28
PT826375E (pt) 2005-02-28
TR199700872A3 (tr) 1999-04-21
NO973940D0 (no) 1997-08-27
HUP9701437A2 (hu) 1998-03-30
JP4593697B2 (ja) 2010-12-08
AR008807A1 (es) 2000-02-23
CA2213151A1 (en) 1998-02-28
CZ218497A3 (cs) 1998-03-18
AU3530997A (en) 1998-03-05
CA2213151C (en) 2008-04-01
DK0826375T3 (da) 2005-01-24
CZ295329B6 (cs) 2005-07-13
AU722151B2 (en) 2000-07-20
CN1199694C (zh) 2005-05-04

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160827