BR9610511A - Molécula de dna de forma circular útil em terapia gênica compreendendo ao menos uma sequência nucléica de interesse processo para sua produção célula recombinante composição farmacêutica utilização de uma molécula de dna e processo de produção de uma proteína recombinante - Google Patents

Molécula de dna de forma circular útil em terapia gênica compreendendo ao menos uma sequência nucléica de interesse processo para sua produção célula recombinante composição farmacêutica utilização de uma molécula de dna e processo de produção de uma proteína recombinante

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Publication number
BR9610511A
BR9610511A BR9610511A BR9610511A BR9610511A BR 9610511 A BR9610511 A BR 9610511A BR 9610511 A BR9610511 A BR 9610511A BR 9610511 A BR9610511 A BR 9610511A BR 9610511 A BR9610511 A BR 9610511A
Authority
BR
Brazil
Prior art keywords
dna molecule
production
gene therapy
pharmaceutical composition
interest
Prior art date
Application number
BR9610511A
Other languages
English (en)
Other versions
BR9610511B1 (pt
BRPI9610511B8 (pt
Inventor
Joel Crouzet
Fabienne Soubrier
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9482580&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9610511(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of BR9610511A publication Critical patent/BR9610511A/pt
Publication of BR9610511B1 publication Critical patent/BR9610511B1/pt
Publication of BRPI9610511B8 publication Critical patent/BRPI9610511B8/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/501—Fibroblast growth factor [FGF] acidic FGF [aFGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/69—Increasing the copy number of the vector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
BRPI9610511A 1995-09-15 1996-09-13 construções de dna, úteis em terapia genética, compreendendo ao menos uma sequência nucléica de interesse e composição farmacêutica. BRPI9610511B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9510825A FR2738842B1 (fr) 1995-09-15 1995-09-15 Molecule d'adn circulaire a origine de replication conditionnelle, leur procede de preparation et leur utilisation en therapie genique
PCT/FR1996/001414 WO1997010343A1 (fr) 1995-09-15 1996-09-13 Molecule d'adn circulaire a origine de replication conditionnelle, leur procede de preparation et leur utilisation en therapie genique

Publications (3)

Publication Number Publication Date
BR9610511A true BR9610511A (pt) 1999-01-26
BR9610511B1 BR9610511B1 (pt) 2010-10-19
BRPI9610511B8 BRPI9610511B8 (pt) 2016-11-08

Family

ID=9482580

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9610511A BRPI9610511B8 (pt) 1995-09-15 1996-09-13 construções de dna, úteis em terapia genética, compreendendo ao menos uma sequência nucléica de interesse e composição farmacêutica.

Country Status (20)

Country Link
US (3) US6977174B2 (pt)
EP (3) EP0850310B1 (pt)
JP (3) JP3818665B2 (pt)
KR (1) KR100522369B1 (pt)
AT (3) ATE284966T1 (pt)
BR (1) BRPI9610511B8 (pt)
CA (1) CA2229307C (pt)
CZ (1) CZ294525B6 (pt)
DE (3) DE69636878T2 (pt)
DK (3) DK0850310T3 (pt)
ES (3) ES2281721T3 (pt)
FR (1) FR2738842B1 (pt)
HU (1) HU224400B1 (pt)
IL (4) IL123641A0 (pt)
NO (1) NO323975B1 (pt)
PT (3) PT850310E (pt)
SK (1) SK285317B6 (pt)
TW (1) TWI231826B (pt)
WO (1) WO1997010343A1 (pt)
ZA (1) ZA967640B (pt)

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Also Published As

Publication number Publication date
NO981044L (no) 1998-03-10
SK285317B6 (sk) 2006-10-05
ATE492642T1 (de) 2011-01-15
IL173399A (en) 2010-11-30
DK0850310T3 (da) 2005-04-25
PT850310E (pt) 2005-05-31
WO1997010343A1 (fr) 1997-03-20
ES2357098T3 (es) 2011-04-18
BR9610511B1 (pt) 2010-10-19
US20090149406A1 (en) 2009-06-11
DK1724354T3 (da) 2011-04-04
TWI231826B (en) 2005-05-01
SK34798A3 (en) 1998-11-04
MX9802005A (es) 1998-08-30
EP0850310A1 (fr) 1998-07-01
DK1508620T3 (da) 2007-05-29
FR2738842B1 (fr) 1997-10-31
JP2000501281A (ja) 2000-02-08
JP2006136328A (ja) 2006-06-01
US20010014476A1 (en) 2001-08-16
EP0850310B1 (fr) 2004-12-15
PT1508620E (pt) 2007-05-31
FR2738842A1 (fr) 1997-03-21
HU224400B1 (hu) 2005-08-29
ATE284966T1 (de) 2005-01-15
JP4585435B2 (ja) 2010-11-24
AU6992496A (en) 1997-04-01
DE69638314D1 (de) 2011-02-03
DE69636878T2 (de) 2007-11-08
NO323975B1 (no) 2007-07-30
EP1724354A2 (fr) 2006-11-22
HUP9900018A3 (en) 2001-10-29
IL123641A0 (en) 1998-10-30
IL207348A0 (en) 2010-12-30
CA2229307A1 (fr) 1997-03-20
CZ78898A3 (cs) 1998-06-17
US20090130674A1 (en) 2009-05-21
ZA967640B (en) 1997-03-25
ES2281721T3 (es) 2007-10-01
BRPI9610511B8 (pt) 2016-11-08
JP3818665B2 (ja) 2006-09-06
EP1724354B1 (fr) 2010-12-22
KR100522369B1 (ko) 2006-10-24
US6977174B2 (en) 2005-12-20
EP1508620A1 (fr) 2005-02-23
IL173399A0 (en) 2006-06-11
AU728231B2 (en) 2001-01-04
EP1508620B1 (fr) 2007-01-24
KR19990044683A (ko) 1999-06-25
JP4756014B2 (ja) 2011-08-24
IL123641A (en) 2006-06-11
NO981044D0 (no) 1998-03-10
DE69634043T2 (de) 2005-08-18
ES2233975T3 (es) 2005-06-16
CA2229307C (fr) 2013-06-11
JP2007325603A (ja) 2007-12-20
DE69634043D1 (de) 2005-01-20
HUP9900018A1 (hu) 1999-04-28
CZ294525B6 (cs) 2005-01-12
DE69636878D1 (de) 2007-03-15
PT1724354E (pt) 2011-03-09
EP1724354A3 (fr) 2008-10-29
ATE352630T1 (de) 2007-02-15

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