BR9509517A - Composição lipossômica composição farmacéutica e processo para a preparação de composições lipossómicas - Google Patents
Composição lipossômica composição farmacéutica e processo para a preparação de composições lipossómicasInfo
- Publication number
- BR9509517A BR9509517A BR9509517A BR9509517A BR9509517A BR 9509517 A BR9509517 A BR 9509517A BR 9509517 A BR9509517 A BR 9509517A BR 9509517 A BR9509517 A BR 9509517A BR 9509517 A BR9509517 A BR 9509517A
- Authority
- BR
- Brazil
- Prior art keywords
- weight
- composition
- pct
- liposomic
- selegilin
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 2
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 208000003926 Myelitis Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000000945 filler Substances 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 201000003152 motion sickness Diseases 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
- Dental Preparations (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9403073A HU223475B1 (hu) | 1994-10-24 | 1994-10-24 | Selegilint tartalmazó liposzoma-készítmény és eljárás ennek előállítására |
| PCT/HU1995/000052 WO1996012472A1 (en) | 1994-10-24 | 1995-10-20 | Liposome composition containing selegilin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9509517A true BR9509517A (pt) | 1997-12-30 |
Family
ID=10985697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9509517A BR9509517A (pt) | 1994-10-24 | 1995-10-20 | Composição lipossômica composição farmacéutica e processo para a preparação de composições lipossómicas |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US5888536A (pt) |
| EP (1) | EP0788349B1 (pt) |
| JP (1) | JPH10507749A (pt) |
| KR (1) | KR100313149B1 (pt) |
| CN (1) | CN1084186C (pt) |
| AT (1) | ATE205387T1 (pt) |
| AU (1) | AU691348B2 (pt) |
| BG (1) | BG63327B1 (pt) |
| BR (1) | BR9509517A (pt) |
| CA (1) | CA2203513C (pt) |
| CZ (1) | CZ287349B6 (pt) |
| DE (1) | DE69522701T2 (pt) |
| DK (1) | DK0788349T3 (pt) |
| EE (1) | EE03418B1 (pt) |
| ES (1) | ES2160718T3 (pt) |
| FI (1) | FI971743A0 (pt) |
| HU (1) | HU223475B1 (pt) |
| IL (1) | IL115754A (pt) |
| NO (1) | NO316354B1 (pt) |
| NZ (1) | NZ294660A (pt) |
| PL (1) | PL183104B1 (pt) |
| PT (1) | PT788349E (pt) |
| RO (1) | RO116768B1 (pt) |
| RU (1) | RU2159106C2 (pt) |
| SK (1) | SK281599B6 (pt) |
| TW (1) | TW412420B (pt) |
| UA (1) | UA44289C2 (pt) |
| WO (1) | WO1996012472A1 (pt) |
| YU (1) | YU49313B (pt) |
| ZA (1) | ZA958999B (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2319318A1 (en) * | 1998-01-27 | 1999-07-29 | Thomas N. Thomas | Methods of treatment using mao-a and mao-b inhibitors such as l-deprenyl |
| DE19814257A1 (de) | 1998-03-31 | 1999-10-07 | Asta Medica Ag | Brauseformulierungen |
| GB9815785D0 (en) * | 1998-07-20 | 1998-09-16 | Cerebrus Ltd | Chemical compounds |
| CN102293746A (zh) * | 2003-09-09 | 2011-12-28 | 吉里德科学公司 | 治疗性脂质体 |
| WO2006082588A2 (en) * | 2005-02-07 | 2006-08-10 | Pharmalight Inc. | Method and device for ophthalmic administration of active pharmaceutical ingredients |
| CN1813679A (zh) * | 2005-11-30 | 2006-08-09 | 上海医药(集团)有限公司 | 一种紫杉烷脂质体冻干组合物及其制备方法 |
| US9445975B2 (en) * | 2008-10-03 | 2016-09-20 | Access Business Group International, Llc | Composition and method for preparing stable unilamellar liposomal suspension |
| JP5693026B2 (ja) * | 2010-03-12 | 2015-04-01 | 株式会社フジモト・コーポレーション | セレギリン含有貼付製剤 |
| JP5623102B2 (ja) * | 2010-03-12 | 2014-11-12 | 株式会社フジモト・コーポレーション | セレギリン含有貼付製剤 |
| WO2013168172A1 (en) * | 2012-05-10 | 2013-11-14 | Painreform Ltd. | Depot formulations of a local anesthetic and methods for preparation thereof |
| AU2015326378B2 (en) * | 2014-09-29 | 2021-01-21 | Council Of Scientific & Industrial Research | A formulation useful for delivery of neuro protecting agent |
| EP3600435B1 (en) * | 2017-03-23 | 2024-03-20 | Lipid Systems sp. z.o.o. | High-efficiency encapsulation of hydrophilic compounds in unilamellar liposomes |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH588887A5 (pt) * | 1974-07-19 | 1977-06-15 | Battelle Memorial Institute | |
| US4485054A (en) * | 1982-10-04 | 1984-11-27 | Lipoderm Pharmaceuticals Limited | Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV) |
| US4761288A (en) * | 1984-09-24 | 1988-08-02 | Mezei Associates Limited | Multiphase liposomal drug delivery system |
| GB8807504D0 (en) * | 1988-03-29 | 1988-05-05 | Sandoz Ltd | Improvements in/relating to organic compounds |
| US4937078A (en) * | 1988-08-26 | 1990-06-26 | Mezei Associates Limited | Liposomal local anesthetic and analgesic products |
| FR2713087B1 (fr) * | 1993-11-30 | 1996-02-23 | Saurat Jean Hilaire | Utilisation de la sélégiline et ses dérivés pour la préparation d'un médicament destiné au traitement du psoriasis. |
-
1994
- 1994-10-24 HU HU9403073A patent/HU223475B1/hu not_active IP Right Cessation
-
1995
- 1995-10-20 ES ES95935530T patent/ES2160718T3/es not_active Expired - Lifetime
- 1995-10-20 JP JP8513742A patent/JPH10507749A/ja active Pending
- 1995-10-20 SK SK517-97A patent/SK281599B6/sk unknown
- 1995-10-20 NZ NZ294660A patent/NZ294660A/en not_active IP Right Cessation
- 1995-10-20 RO RO97-00792A patent/RO116768B1/ro unknown
- 1995-10-20 EE EE9700102A patent/EE03418B1/xx not_active IP Right Cessation
- 1995-10-20 CA CA002203513A patent/CA2203513C/en not_active Expired - Fee Related
- 1995-10-20 UA UA97052395A patent/UA44289C2/uk unknown
- 1995-10-20 PT PT95935530T patent/PT788349E/pt unknown
- 1995-10-20 AT AT95935530T patent/ATE205387T1/de not_active IP Right Cessation
- 1995-10-20 WO PCT/HU1995/000052 patent/WO1996012472A1/en active IP Right Grant
- 1995-10-20 AU AU37518/95A patent/AU691348B2/en not_active Ceased
- 1995-10-20 KR KR1019970702682A patent/KR100313149B1/ko not_active IP Right Cessation
- 1995-10-20 BR BR9509517A patent/BR9509517A/pt not_active IP Right Cessation
- 1995-10-20 RU RU97108051/14A patent/RU2159106C2/ru not_active IP Right Cessation
- 1995-10-20 PL PL95319875A patent/PL183104B1/pl not_active IP Right Cessation
- 1995-10-20 EP EP95935530A patent/EP0788349B1/en not_active Expired - Lifetime
- 1995-10-20 CZ CZ19971147A patent/CZ287349B6/cs not_active IP Right Cessation
- 1995-10-20 CN CN95195853A patent/CN1084186C/zh not_active Expired - Fee Related
- 1995-10-20 DK DK95935530T patent/DK0788349T3/da active
- 1995-10-20 US US08/817,433 patent/US5888536A/en not_active Expired - Fee Related
- 1995-10-20 DE DE69522701T patent/DE69522701T2/de not_active Expired - Fee Related
- 1995-10-24 ZA ZA958999A patent/ZA958999B/xx unknown
- 1995-10-24 IL IL11575495A patent/IL115754A/xx not_active IP Right Cessation
- 1995-10-24 TW TW084111224A patent/TW412420B/zh not_active IP Right Cessation
- 1995-10-25 YU YU67195A patent/YU49313B/sh unknown
-
1997
- 1997-04-22 BG BG101432A patent/BG63327B1/bg unknown
- 1997-04-23 NO NO19971870A patent/NO316354B1/no unknown
- 1997-04-23 FI FI971743A patent/FI971743A0/fi not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB36 | Technical and formal requirements: requirement - article 36 of industrial property law | ||
| FB36 | Technical and formal requirements: requirement - article 36 of industrial property law | ||
| FB36 | Technical and formal requirements: requirement - article 36 of industrial property law | ||
| FF | Decision: intention to grant | ||
| FG9A | Patent or certificate of addition granted | ||
| B24C | Patent annual fee: request for for restoration |
Free format text: REFERENTE 13A E 14A ANUIDADES. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2049 DE 13/04/2010 E COMPROVAR RECOLHIMENTO DA 15A , 16A , 17A E 18A ANUIDADES. |