YU67195A - Lipozomni preparat koji sadrži selegilin i/ili njegovu so - Google Patents

Lipozomni preparat koji sadrži selegilin i/ili njegovu so

Info

Publication number
YU67195A
YU67195A YU67195A YU67195A YU67195A YU 67195 A YU67195 A YU 67195A YU 67195 A YU67195 A YU 67195A YU 67195 A YU67195 A YU 67195A YU 67195 A YU67195 A YU 67195A
Authority
YU
Yugoslavia
Prior art keywords
weight
liposomic
pct
selegilin
composition
Prior art date
Application number
YU67195A
Other languages
English (en)
Other versions
YU49313B (sh
Inventor
Mezei
Gaal
Szekacs
Szebeni
Marmarosi
Magyar
Lengyel
Szatmari
Turi
Original Assignee
Chinoin Gyogyszer Es Vegyeszeti Termekek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszeti Termekek filed Critical Chinoin Gyogyszer Es Vegyeszeti Termekek
Publication of YU67195A publication Critical patent/YU67195A/sh
Publication of YU49313B publication Critical patent/YU49313B/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Detergent Compositions (AREA)
  • Dental Preparations (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Ovaj pronalazak obezbeđuje lipozomni preparat koji sadrži kao aktivni sastojak (-)-N-alfa-(2-propinilfeniletilamin) (selegilin) i/ili njegovu so. Ovaj preparat sadrži: 0,1-40 mas.% selegilina i/ili njegove soli, 2-40 mas.% lipida, poželjno fosfolipida, 0-10 mas.% holesterola, 0-20 mas.% alkohola 0-25 mas.% glikola, 0-3 mas.% antioksidansa, 0-3 mas.% konzervansa, 0-20 mas.% agensa koji utiče na viskoznost, 0-50 mas.% ciklodekstrina ili derivata ciklodekstrina, 30-90 mas.% vode. Ovaj pronalazak se odnosi na farmaceutski preparat koji sadrži opisan lipozomni preparat i ako se želi, uobičajene agense za punjenje ili razblaživanje i druge pomoćne agense, poželjno u oralnom, parenteralnom ili transdermalnom obliku. Ovaj pronalazak obezbeđuje postupak za dobijanje lipozomnih preparata koji sadrže selegilin i/ili njegovu so. Stoga lipozomni preparat ovog pronalaska može biti dat za tretiranje Alzheimerove bolesti, Parkinsonove bolesti, depresije, šloga, bolesti kretanja ili mielitisa.
YU67195A 1994-10-24 1995-10-25 Lipozomni preparat koji sadrži selegilin i/ili njegovu so YU49313B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9403073A HU223475B1 (hu) 1994-10-24 1994-10-24 Selegilint tartalmazó liposzoma-készítmény és eljárás ennek előállítására

Publications (2)

Publication Number Publication Date
YU67195A true YU67195A (sh) 1998-07-10
YU49313B YU49313B (sh) 2005-06-10

Family

ID=10985697

Family Applications (1)

Application Number Title Priority Date Filing Date
YU67195A YU49313B (sh) 1994-10-24 1995-10-25 Lipozomni preparat koji sadrži selegilin i/ili njegovu so

Country Status (30)

Country Link
US (1) US5888536A (sh)
EP (1) EP0788349B1 (sh)
JP (1) JPH10507749A (sh)
KR (1) KR100313149B1 (sh)
CN (1) CN1084186C (sh)
AT (1) ATE205387T1 (sh)
AU (1) AU691348B2 (sh)
BG (1) BG63327B1 (sh)
BR (1) BR9509517A (sh)
CA (1) CA2203513C (sh)
CZ (1) CZ287349B6 (sh)
DE (1) DE69522701T2 (sh)
DK (1) DK0788349T3 (sh)
EE (1) EE03418B1 (sh)
ES (1) ES2160718T3 (sh)
FI (1) FI971743A (sh)
HU (1) HU223475B1 (sh)
IL (1) IL115754A (sh)
NO (1) NO316354B1 (sh)
NZ (1) NZ294660A (sh)
PL (1) PL183104B1 (sh)
PT (1) PT788349E (sh)
RO (1) RO116768B1 (sh)
RU (1) RU2159106C2 (sh)
SK (1) SK281599B6 (sh)
TW (1) TW412420B (sh)
UA (1) UA44289C2 (sh)
WO (1) WO1996012472A1 (sh)
YU (1) YU49313B (sh)
ZA (1) ZA958999B (sh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1052983A2 (en) * 1998-01-27 2000-11-22 Thomas N. Thomas Use of an mao-a or mao-b inhibitor for the treatment of vascular disorders
DE19814257A1 (de) 1998-03-31 1999-10-07 Asta Medica Ag Brauseformulierungen
GB9815785D0 (en) * 1998-07-20 1998-09-16 Cerebrus Ltd Chemical compounds
CA2536393A1 (en) * 2003-09-09 2005-06-16 Gilead Sciences, Inc. Use of liposomes which are small unilamellar vesicles for the removal of an entity from a biological sample
US20080233053A1 (en) * 2005-02-07 2008-09-25 Pharmalight Inc. Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients
CN1813679A (zh) * 2005-11-30 2006-08-09 上海医药(集团)有限公司 一种紫杉烷脂质体冻干组合物及其制备方法
US9445975B2 (en) * 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
JP5693026B2 (ja) * 2010-03-12 2015-04-01 株式会社フジモト・コーポレーション セレギリン含有貼付製剤
JP5623102B2 (ja) * 2010-03-12 2014-11-12 株式会社フジモト・コーポレーション セレギリン含有貼付製剤
WO2013168167A1 (en) 2012-05-10 2013-11-14 Painreform Ltd. Depot formulations of a hydrophobic active ingredient and methods for preparation thereof
WO2016051424A1 (en) * 2014-09-29 2016-04-07 Council Of Scientific & Industrial Research A formulation useful for delivery of neuro protecting agent
PL3600435T3 (pl) * 2017-03-23 2024-06-17 Lipid Systems Sp. Z.O.O. Wysokowydajne kapsułkowanie związków hydrofilnych w liposomach jednowarstwowych

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH588887A5 (sh) * 1974-07-19 1977-06-15 Battelle Memorial Institute
US4485054A (en) * 1982-10-04 1984-11-27 Lipoderm Pharmaceuticals Limited Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
US4761288A (en) * 1984-09-24 1988-08-02 Mezei Associates Limited Multiphase liposomal drug delivery system
GB8807504D0 (en) * 1988-03-29 1988-05-05 Sandoz Ltd Improvements in/relating to organic compounds
US4937078A (en) * 1988-08-26 1990-06-26 Mezei Associates Limited Liposomal local anesthetic and analgesic products
FR2713087B1 (fr) * 1993-11-30 1996-02-23 Saurat Jean Hilaire Utilisation de la sélégiline et ses dérivés pour la préparation d'un médicament destiné au traitement du psoriasis.

Also Published As

Publication number Publication date
KR970706797A (ko) 1997-12-01
RU2159106C2 (ru) 2000-11-20
EP0788349B1 (en) 2001-09-12
FI971743A0 (fi) 1997-04-23
PL319875A1 (en) 1997-09-01
HU9403073D0 (en) 1994-12-28
BG101432A (en) 1997-12-30
YU49313B (sh) 2005-06-10
DK0788349T3 (da) 2001-11-26
HUT76053A (en) 1997-06-30
WO1996012472A1 (en) 1996-05-02
RO116768B1 (ro) 2001-06-29
ES2160718T3 (es) 2001-11-16
CN1084186C (zh) 2002-05-08
FI971743A (fi) 1997-04-23
IL115754A0 (en) 1996-01-19
MX9703019A (es) 1997-10-31
SK51797A3 (en) 1997-11-05
CA2203513A1 (en) 1996-05-02
UA44289C2 (uk) 2002-02-15
KR100313149B1 (ko) 2002-02-19
BR9509517A (pt) 1997-12-30
EP0788349A1 (en) 1997-08-13
AU3751895A (en) 1996-05-15
PL183104B1 (pl) 2002-05-31
DE69522701T2 (de) 2002-07-11
IL115754A (en) 1999-07-14
EE03418B1 (et) 2001-06-15
NZ294660A (en) 1998-05-27
PT788349E (pt) 2001-12-28
JPH10507749A (ja) 1998-07-28
NO316354B1 (no) 2004-01-19
BG63327B1 (bg) 2001-10-31
TW412420B (en) 2000-11-21
AU691348B2 (en) 1998-05-14
CN1163563A (zh) 1997-10-29
EE9700102A (et) 1997-10-15
ZA958999B (en) 1996-05-15
ATE205387T1 (de) 2001-09-15
NO971870L (no) 1997-06-24
SK281599B6 (sk) 2001-05-10
US5888536A (en) 1999-03-30
DE69522701D1 (de) 2001-10-18
HU223475B1 (hu) 2004-07-28
CZ287349B6 (en) 2000-10-11
CZ114797A3 (en) 1997-10-15
CA2203513C (en) 2001-10-09
NO971870D0 (no) 1997-04-23

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