BR9408378A - Composto sal farmaceuticamente aceitável composição farmacêutica e processos para o tratamento de um paciente que sofreu um derrame e que sofre de uma condição de perda progressiva de função de sistema nervoso central e para melhorar os efeitos colaterais causados em um paciente por tratamento antineoplástico de doença que produz danos oxidativos - Google Patents

Composto sal farmaceuticamente aceitável composição farmacêutica e processos para o tratamento de um paciente que sofreu um derrame e que sofre de uma condição de perda progressiva de função de sistema nervoso central e para melhorar os efeitos colaterais causados em um paciente por tratamento antineoplástico de doença que produz danos oxidativos

Info

Publication number
BR9408378A
BR9408378A BR9408378A BR9408378A BR9408378A BR 9408378 A BR9408378 A BR 9408378A BR 9408378 A BR9408378 A BR 9408378A BR 9408378 A BR9408378 A BR 9408378A BR 9408378 A BR9408378 A BR 9408378A
Authority
BR
Brazil
Prior art keywords
patient
nervous system
central nervous
stroke
pharmaceutically acceptable
Prior art date
Application number
BR9408378A
Other languages
English (en)
Portuguese (pt)
Inventor
John M Carney
Original Assignee
Oklahoma Med Res Found
Univ Kentucky Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oklahoma Med Res Found, Univ Kentucky Res Found filed Critical Oklahoma Med Res Found
Publication of BR9408378A publication Critical patent/BR9408378A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/46—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BR9408378A 1993-12-23 1994-12-22 Composto sal farmaceuticamente aceitável composição farmacêutica e processos para o tratamento de um paciente que sofreu um derrame e que sofre de uma condição de perda progressiva de função de sistema nervoso central e para melhorar os efeitos colaterais causados em um paciente por tratamento antineoplástico de doença que produz danos oxidativos BR9408378A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/173,579 US5488145A (en) 1993-12-23 1993-12-23 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps
PCT/US1994/014545 WO1995017876A2 (en) 1993-12-23 1994-12-22 2,4-disulphophenyl butylnitrone, its salts, and their use as pharmaceutical spintraps

Publications (1)

Publication Number Publication Date
BR9408378A true BR9408378A (pt) 1997-08-19

Family

ID=22632663

Family Applications (2)

Application Number Title Priority Date Filing Date
BR9408378A BR9408378A (pt) 1993-12-23 1994-12-22 Composto sal farmaceuticamente aceitável composição farmacêutica e processos para o tratamento de um paciente que sofreu um derrame e que sofre de uma condição de perda progressiva de função de sistema nervoso central e para melhorar os efeitos colaterais causados em um paciente por tratamento antineoplástico de doença que produz danos oxidativos
BR1100626-9A BR1100626A (pt) 1993-12-23 1997-05-13 Composto, sal farmaceuticamente aceitável, e, composição farmacêutica

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR1100626-9A BR1100626A (pt) 1993-12-23 1997-05-13 Composto, sal farmaceuticamente aceitável, e, composição farmacêutica

Country Status (28)

Country Link
US (4) US5488145A (https=)
EP (1) EP0736004B1 (https=)
JP (3) JP3412821B2 (https=)
KR (1) KR100370522B1 (https=)
CN (1) CN1070176C (https=)
AT (1) ATE192736T1 (https=)
AU (1) AU679835B2 (https=)
BR (2) BR9408378A (https=)
CA (1) CA2179521C (https=)
CZ (1) CZ289629B6 (https=)
DE (1) DE69424441T2 (https=)
DK (1) DK0736004T3 (https=)
ES (1) ES2145264T3 (https=)
FI (1) FI111718B (https=)
GR (1) GR3034134T3 (https=)
HR (1) HRP950358B1 (https=)
HU (1) HU221167B1 (https=)
MY (1) MY114178A (https=)
NO (1) NO306457B1 (https=)
NZ (1) NZ279025A (https=)
PL (1) PL185189B1 (https=)
PT (1) PT736004E (https=)
RU (1) RU2159231C2 (https=)
SG (1) SG64903A1 (https=)
SK (1) SK282403B6 (https=)
TW (1) TW299315B (https=)
UA (1) UA45964C2 (https=)
WO (1) WO1995017876A2 (https=)

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US20040208875A1 (en) * 1995-03-15 2004-10-21 Queen's University At Kingston Method for treating amyloidosis
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US6376540B1 (en) * 1996-07-19 2002-04-23 Centaur Pharmaceuticals, Inc. Furan nitrone compounds
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US6046232A (en) * 1997-10-17 2000-04-04 Centaur Pharmaceuticals, Inc. α-aryl-N-alkylnitrones and pharmaceutical compositions containing the same
AU2226999A (en) * 1998-01-16 1999-08-02 Renovis, Inc. Thiophene nitrone compounds
JP2002509143A (ja) * 1998-01-16 2002-03-26 センター ファーマシューティカルズ， インコーポレイテッド チオエーテルフランニトロン化合物
JP2002506022A (ja) * 1998-03-13 2002-02-26 センター ファーマシューティカルズ， インコーポレイテッド 新脈管形成の阻害
US6083989A (en) * 1999-05-18 2000-07-04 Centaur Pharmaceuticals, Inc. Aryl nitrone therapeutics for the treatment of inflammatory bowel disease
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UA66401C2 (en) 1998-12-02 2004-05-17 Sentor Pharmaceuticals Inc 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical composition containing the same
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CA2069961C (en) * 1989-10-17 2000-05-02 John M. Carney Method and compositions for inhibition of disorders associated with oxidative damage
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US5488145A (en) * 1993-12-23 1996-01-30 Oklahoma Medical Research Foundation 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps

Also Published As

Publication number Publication date
NO962637D0 (no) 1996-06-20
US5475032A (en) 1995-12-12
HU221167B1 (en) 2002-08-28
SG64903A1 (en) 1999-05-25
CZ289629B6 (cs) 2002-03-13
FI111718B (fi) 2003-09-15
BR1100626A (pt) 1999-11-23
HK1001768A1 (en) 1998-07-10
CA2179521A1 (en) 1995-07-06
JPH09507232A (ja) 1997-07-22
SK282403B6 (sk) 2002-01-07
ES2145264T3 (es) 2000-07-01
CN1070176C (zh) 2001-08-29
US5780510A (en) 1998-07-14
JP2001010953A (ja) 2001-01-16
PL185189B1 (pl) 2003-03-31
CA2179521C (en) 2002-03-19
EP0736004A1 (en) 1996-10-09
HRP950358B1 (en) 2001-04-30
JP2004075696A (ja) 2004-03-11
FI962589L (fi) 1996-08-20
CZ177596A3 (en) 1996-12-11
NO306457B1 (no) 1999-11-08
KR100370522B1 (ko) 2003-05-16
GR3034134T3 (en) 2000-11-30
RU2159231C2 (ru) 2000-11-20
HU9601739D0 (en) 1996-08-28
AU679835B2 (en) 1997-07-10
ATE192736T1 (de) 2000-05-15
WO1995017876A3 (en) 1995-08-10
PT736004E (pt) 2000-09-29
WO1995017876A2 (en) 1995-07-06
AU1552795A (en) 1995-07-17
PL315154A1 (en) 1996-10-14
NZ279025A (en) 1998-02-26
SK78896A3 (en) 1997-09-10
DE69424441T2 (de) 2000-10-12
UA45964C2 (uk) 2002-05-15
HK1008294A1 (en) 1999-05-07
FI962589A0 (fi) 1996-06-20
US5488145A (en) 1996-01-30
US5508305A (en) 1996-04-16
HUT76788A (en) 1997-11-28
DE69424441D1 (de) 2000-06-15
JP3412821B2 (ja) 2003-06-03
NO962637L (no) 1996-08-13
DK0736004T3 (da) 2000-10-09
EP0736004B1 (en) 2000-05-10
HRP950358A2 (en) 1997-08-31
CN1156447A (zh) 1997-08-06
TW299315B (https=) 1997-03-01
MY114178A (en) 2002-08-30

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